LOCUS       NM_028013               4470 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus endonuclease domain containing 1 (Endod1), mRNA.
ACCESSION   NM_028013
VERSION     NM_028013.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4470)
  AUTHORS   Tang,Z., Zeng,M., Wang,X., Guo,C., Yue,P., Zhang,X., Lou,H.,
            Chen,J., Mu,D., Kong,D., Carr,A.M. and Liu,C.
  TITLE     Synthetic lethality between TP53 and ENDOD1
  JOURNAL   Nat Commun 13 (1), 2861 (2022)
   PUBMED   35606358
  REMARK    GeneRIF: Synthetic lethality between TP53 and ENDOD1.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4470)
  AUTHORS   Miller,J.A., Nathanson,J., Franjic,D., Shim,S., Dalley,R.A.,
            Shapouri,S., Smith,K.A., Sunkin,S.M., Bernard,A., Bennett,J.L.,
            Lee,C.K., Hawrylycz,M.J., Jones,A.R., Amaral,D.G., Sestan,N.,
            Gage,F.H. and Lein,E.S.
  TITLE     Conserved molecular signatures of neurogenesis in the hippocampal
            subgranular zone of rodents and primates
  JOURNAL   Development 140 (22), 4633-4644 (2013)
   PUBMED   24154525
REFERENCE   3  (bases 1 to 4470)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   4  (bases 1 to 4470)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK173036.1 and BY483505.1.
            
            On Nov 15, 2007 this sequence version replaced NM_028013.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK173036.1, AK078056.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164133, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4454              AK173036.1         1-4454
            4455-4470           BY483505.1         347-362
FEATURES             Location/Qualifiers
     source          1..4470
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 3.96 cM"
     gene            1..4470
                     /gene="Endod1"
                     /gene_synonym="2210414F18Rik; 2310067E08Rik"
                     /note="endonuclease domain containing 1"
                     /db_xref="GeneID:71946"
                     /db_xref="MGI:MGI:1919196"
     exon            1..572
                     /gene="Endod1"
                     /gene_synonym="2210414F18Rik; 2310067E08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             273..1778
                     /gene="Endod1"
                     /gene_synonym="2210414F18Rik; 2310067E08Rik"
                     /note="endonuclease domain-containing 1 protein"
                     /codon_start=1
                     /product="endonuclease domain-containing 1 protein
                     precursor"
                     /protein_id="NP_082289.2"
                     /db_xref="CCDS:CCDS22821.1"
                     /db_xref="GeneID:71946"
                     /db_xref="MGI:MGI:1919196"
                     /translation="MGCARWLALGGLLALAGLLQARLLLPQQAGFGECDRFFYKGTPP
                     AGLATEAHVRICQRFAGSERFATLYSPGHRIPVFSAFRAARPASRSAEQRGLLEPQID
                     DPDSNLEEVIDEANALTSVDNLGSKQALNADYIDSDYEIGQLYPFPLNSDLQMATFPL
                     TNSVPMTQSFRERWHMNLNSLMDRALIPHCSEGKDLYILTGAVPSEHRVKGKVTIPEF
                     VWLAACCAVPGEGWAMGFIKHTQDIDVIEDVMLRDLEKLLPHKPQLFQDNCGEMEQDT
                     EKMKKILEVVNQVQDEERSLQSQERMSPLASTQSQRSALLSPEAPPEGGSSFLGQVLG
                     FLATPFIKLFQLIYYLVTAVLRNIVHLLWLVAKQAINTVESCLYHLGEATVSYLVAIG
                     QELVSIPWKVLKVVAKVIRAFLRILCCLLKAVCRALSIPLRVLVDVATFPVYTVGAIP
                     IVCKDIAVGLGGTLSLLFDTAFGTVGGLFQIVFSVFKRIGYKVTLDNSGEF"
     exon            573..4470
                     /gene="Endod1"
                     /gene_synonym="2210414F18Rik; 2310067E08Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2099..2104
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Endod1"
                     /gene_synonym="2210414F18Rik; 2310067E08Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2121
                     /gene="Endod1"
                     /gene_synonym="2210414F18Rik; 2310067E08Rik"
                     /note="major polyA site"
     regulatory      2380..2385
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Endod1"
                     /gene_synonym="2210414F18Rik; 2310067E08Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2402
                     /gene="Endod1"
                     /gene_synonym="2210414F18Rik; 2310067E08Rik"
     regulatory      4433..4438
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Endod1"
                     /gene_synonym="2210414F18Rik; 2310067E08Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4455
                     /gene="Endod1"
                     /gene_synonym="2210414F18Rik; 2310067E08Rik"
                     /note="major polyA site"
ORIGIN      
        1 cgcaaggtcc gacttctcag cgccagccct ggggacagcc ccttgggcta agccagtcca
       61 gcgcggaggg ggagctctgg cacacagcag cgccgcggca ggtgtccggt ctccaggggt
      121 gggtgcagcc gcagaaagcc gcggctgagc actgcagcca tcttcggggt ggaggcggag
      181 aaggggcgcg gccttggccc agagccgccc cgccagagag gctcaccgcg gacttccctg
      241 ctctagcggc gcccggccgc gcagaggccg ccatgggctg tgcgcgctgg ctggcgctgg
      301 gcggcctcct ggccctggca gggctgttgc aggcccggct gctgctcccg cagcaagcgg
      361 gcttcggcga atgcgaccgt ttcttctaca aggggacccc acccgccggg ctggcgaccg
      421 aagcgcacgt gaggatctgt caacgcttcg cgggctccga gcgcttcgcc actctgtaca
      481 gtcctggcca ccgcatcccc gtgttctccg cgtttcgcgc tgcgcgcccg gcgtcccgca
      541 gtgccgagca gcgcgggctg ctggagccgc agattgatga ccctgacagc aacctcgagg
      601 aggtcattga cgaggccaac gctctcacct cagtggacaa tctgggaagc aagcaagcct
      661 tgaatgcaga ctacattgac tctgactatg aaatcggaca gctgtaccca tttcctctta
      721 acagtgacct ccagatggcc acattcccgc tcacaaattc agttccaatg acccagtctt
      781 tccgggaacg atggcacatg aatctcaaca gcctcatgga ccgagccttg atcccacact
      841 gcagtgaagg caaagacctg tatatcctca cgggggctgt tccctcagag cacagagtta
      901 agggcaaagt gactatccct gaattcgtct ggctggcagc ttgctgtgca gtccctggag
      961 aaggctgggc catgggcttc atcaagcaca cccaggacat tgatgtcata gaagatgtga
     1021 tgctgagaga ccttgagaag ctgcttcctc ataagcctca actgttccag gacaactgtg
     1081 gtgagatgga gcaagataca gagaagatga agaagattct ggaagtggtc aaccaagtcc
     1141 aagatgagga gcggtctctg cagtctcaag agagaatgag tcccctcgcc agcacccaaa
     1201 gccagaggtc tgccctgctg tccccagaag caccaccaga gggagggagc agttttctgg
     1261 gacaagtcct gggtttcctt gctaccccat tcattaagct tttccagtta atttattacc
     1321 ttgttacagc ggtcttaagg aatatagtcc atctcctttg gttggttgcc aagcaggcaa
     1381 taaacactgt tgagagttgc ctataccatc taggcgaagc cactgtctca tacctcgtgg
     1441 ccattggaca agagctggtg agcattccct ggaaagtgct caaggttgtg gccaaagtca
     1501 tccgggcctt cctccggatc ctctgctgtc tgctgaaggc tgtctgccga gctctgagca
     1561 tccctctccg agtccttgtg gatgtagcca ctttccctgt gtatactgtg ggggccattc
     1621 ccattgtgtg caaggacatt gctgtgggcc tgggtggcac cctctcactc ctctttgaca
     1681 ctgcttttgg caccgtaggt ggcttgtttc agattgtttt tagtgtcttc aagcggattg
     1741 gctacaaggt tactttagac aattccgggg agttctagaa cttaaaaacc tagtaatgtc
     1801 cattgtggtg aattttgatt ttctctttta aacagcaggt ttctgttcct tgtcagctac
     1861 tgtgttatgt ttacccagca ggtgtgtatt tttctgcaaa agagtatggc acgctttaaa
     1921 tttgatctaa aagaaatgtt cagggcaggc tcaatgccgt gctccatgtg cgtctgcaac
     1981 tatacaggtg tgcttccctg cgtctgctaa ctttaggact gcgctccgac tcagagggaa
     2041 acacctggca tgacccaggc ttcttatgaa aattataaat aaggaagaag aggatgacat
     2101 taaatgctga aagaaacggt atctcgtgtc tcccaatact cttggagagt taaggcaaac
     2161 taggtctgag tattgttgtc cggtctcagc gtctcctttt cttcctctcc tactctagca
     2221 gtgagccggt gactgctctg ctgaaatttc tccctctcgg tggtagcatc tgctggggct
     2281 ctgacctttg cctaggtctc cagagcttgg ttgagtttaa ttttctccca aagtcaattt
     2341 tgctgaatca caataagcat tttatgccaa atataacaca ataaaaattg aatgcagccc
     2401 cagttggagt agagctggtc cctccaggtg tagaggaagc agcatgaagc agtgctgtgt
     2461 gtccacaggc atgcctaggg aggtttgggt caacttagat tacatcactg gttggtgaca
     2521 ttaaacacaa agatctgcat gttaatctaa tgtgaaactt catattttgc agcatctaat
     2581 ccatcaagtg agtattcagg accataaaac agtctgattt ctctcctgaa acaattattt
     2641 gttataacta tctaggtaat agaaaaaaaa tgaaaaacat tctggtccac ttgggtagaa
     2701 gtatatctct gtacatattt aagaattatt atctcttaga tcattatttt tatagtgtgt
     2761 ttgaggctaa aaatctacca gtccttcatt aatgcaagtt aaatttgaga gcttatttcc
     2821 agttttgatc aatcacttgt tattttaaat cttgcactag aaattataac aaaaggagcc
     2881 aaacttgctt tgtgggaacc aaatattccc atggtgagaa tggattttct agtatcttct
     2941 tcttagcatt ccaaagagtt gctatgaagg agagaggggc caagtgttca cttaacttgg
     3001 ggacgtggcc catggttgtc tggaaattag ttgtaaagac ttggagtcta gaaagaaacc
     3061 acagaggggg cagaacacca gctgttccca gggaacgaat gtgtgtggag ccggaattaa
     3121 atgctgcagg aaaagattcg aatagcacca gagaggacta gcagcagcga gcaagcttcc
     3181 ttgcggccat gacagccact ggtcgggaca gcagacgagc ccttgctcag gtgatgcaca
     3241 ccctttatca aggctcctgg cagcaccttt atgactttcc tctgtcaatg ggagggtgag
     3301 gcttgccctg gcactgatga gtcccacgca gaggcacaag gaggctgtat tgaccttgct
     3361 cgcaggctaa tggaagccag tcatggtgag ctaggacacc ccatcacacc agggtgtgcc
     3421 tccctgggtg taactagcat tttatcacca tcaagacgac aggctctgta tcaactggat
     3481 gtggcatggt taacgaaatg ccaggtattc acaggagaca ttgtgctgac tgcatctcag
     3541 cgaagccccc ttcccctttc agtgaataat ttgcattctg agaggcccta ggagggcact
     3601 cattgtgcac aaacccctta taaggaatca tttggaaaca ctccacccaa ccccctgctg
     3661 ccatattcag ctgtctggtt atttattttt gtgtgacttt ttttttttaa tatgggaaag
     3721 gataataagg caaatgtttc aaacaaaaca aaacaaaaca aacagacaaa aatatatcct
     3781 tcaggttaga gggccgagac ccttcattct ggagtttctt gttggcaggg cctctggttc
     3841 actggaacta gctgtatttg tttttaaagt ccttccagat ctctgggctg atggcccatc
     3901 cccaaaaggc tacttaggct tctgacatgg aggtttagga agttgaaccc tgtcttcagc
     3961 ttggagtttt tgctgtggct tcattctctt ctcaggccct tggggacgtt ggccaacttt
     4021 gtcatttgtg gagctgcttt tctagcctgt gccagccatg ttctcagaca cgccgctctc
     4081 ccttagtgcc ttttccaccc agcgcaaact agggaatgga aggaagccca aggaagctcc
     4141 ctctgctctt cttcatccat ttacctagca acatgcattc ggtcatcaag gttgcagagg
     4201 tggaaagtgc tccatctata aggagtttcc agcatggtag gaaaaaacat ggcacgatcc
     4261 gtgctttgat catgctttga tcatagcaag caccacacgg agagtatttg acccgtttcc
     4321 tgcagcacag gaagaaaacc tgcaagatca ggaagatgaa cactttaatg agcgtgagac
     4381 aaaaccatgt tgaccgtaac tatgtacagt gctgtgcacc ttgcagatgc tcaataaagt
     4441 cgctgctgac agtcactggt tctgtgggct
//
