LOCUS       NM_001381867            5666 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus EMSY, BRCA2-interacting transcriptional repressor
            (Emsy), transcript variant 3, mRNA.
ACCESSION   NM_001381867 XM_030242480
VERSION     NM_001381867.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5666)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5666)
  AUTHORS   Marzio,A., Kurz,E., Sahni,J.M., Di Feo,G., Puccini,J., Jiang,S.,
            Hirsch,C.A., Arbini,A.A., Wu,W.L., Pass,H.I., Bar-Sagi,D.,
            Papagiannakopoulos,T. and Pagano,M.
  TITLE     EMSY inhibits homologous recombination repair and the interferon
            response, promoting lung cancer immune evasion
  JOURNAL   Cell 185 (1), 169-183 (2022)
   PUBMED   34963055
  REMARK    GeneRIF: EMSY inhibits homologous recombination repair and the
            interferon response, promoting lung cancer immune evasion.
REFERENCE   3  (bases 1 to 5666)
  AUTHORS   Ezell,S.A., Polytarchou,C., Hatziapostolou,M., Guo,A., Sanidas,I.,
            Bihani,T., Comb,M.J., Sourvinos,G. and Tsichlis,P.N.
  TITLE     The protein kinase Akt1 regulates the interferon response through
            phosphorylation of the transcriptional repressor EMSY
  JOURNAL   Proc Natl Acad Sci U S A 109 (10), E613-E621 (2012)
   PUBMED   22315412
  REMARK    GeneRIF: Akt1 regulates the interferon response through
            phosphorylation of the transcriptional repressor EMSY
REFERENCE   4  (bases 1 to 5666)
  AUTHORS   Vosseller,K., Trinidad,J.C., Chalkley,R.J., Specht,C.G.,
            Thalhammer,A., Lynn,A.J., Snedecor,J.O., Guan,S.,
            Medzihradszky,K.F., Maltby,D.A., Schoepfer,R. and Burlingame,A.L.
  TITLE     O-linked N-acetylglucosamine proteomics of postsynaptic density
            preparations using lectin weak affinity chromatography and mass
            spectrometry
  JOURNAL   Mol Cell Proteomics 5 (5), 923-934 (2006)
   PUBMED   16452088
REFERENCE   5  (bases 1 to 5666)
  AUTHORS   Ekblad,C.M., Chavali,G.B., Basu,B.P., Freund,S.M., Veprintsev,D.,
            Hughes-Davies,L., Kouzarides,T., Doherty,A.J. and Itzhaki,L.S.
  TITLE     Binding of EMSY to HP1beta: implications for recruitment of HP1beta
            and BS69
  JOURNAL   EMBO Rep 6 (7), 675-680 (2005)
   PUBMED   15947784
REFERENCE   6  (bases 1 to 5666)
  AUTHORS   Hughes-Davies,L., Huntsman,D., Ruas,M., Fuks,F., Bye,J., Chin,S.F.,
            Milner,J., Brown,L.A., Hsu,F., Gilks,B., Nielsen,T., Schulzer,M.,
            Chia,S., Ragaz,J., Cahn,A., Linger,L., Ozdag,H., Cattaneo,E.,
            Jordanova,E.S., Schuuring,E., Yu,D.S., Venkitaraman,A., Ponder,B.,
            Doherty,A., Aparicio,S., Bentley,D., Theillet,C., Ponting,C.P.,
            Caldas,C. and Kouzarides,T.
  TITLE     EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer
  JOURNAL   Cell 115 (5), 523-535 (2003)
   PUBMED   14651845
REFERENCE   7  (bases 1 to 5666)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC111124.8.
            
            On Apr 17, 2020 this sequence version replaced XM_030242480.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.225621.1,
                                           SRR7974084.313.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               AC111124.8         75793-75896
            105-213             AC111124.8         77518-77626
            214-313             AC111124.8         84466-84565
            314-388             AC111124.8         85847-85921
            389-564             AC111124.8         90702-90877
            565-824             AC111124.8         94850-95109
            825-1101            AC111124.8         101963-102239
            1102-1356           AC111124.8         105650-105904
            1357-1506           AC111124.8         110830-110979
            1507-1677           AC111124.8         112901-113071
            1678-1814           AC111124.8         116758-116894
            1815-1988           AC111124.8         119213-119386
            1989-2187           AC111124.8         121505-121703
            2188-2352           AC111124.8         129623-129787
            2353-2508           AC111124.8         131543-131698
            2509-2660           AC111124.8         135186-135337
            2661-3221           AC111124.8         137058-137618
            3222-3701           AC111124.8         138560-139039
            3702-5666           AC111124.8         141486-143450
FEATURES             Location/Qualifiers
     source          1..5666
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 53.86 cM"
     gene            1..5666
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /note="EMSY, BRCA2-interacting transcriptional repressor"
                     /db_xref="GeneID:233545"
                     /db_xref="MGI:MGI:1924203"
     exon            1..104
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            105..213
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..3896
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /note="isoform 3 is encoded by transcript variant 3;
                     protein EMSY; BRCA2-interacting transcriptional repressor
                     EMSY"
                     /codon_start=1
                     /product="BRCA2-interacting transcriptional repressor EMSY
                     isoform 3"
                     /protein_id="NP_001368796.1"
                     /db_xref="GeneID:233545"
                     /db_xref="MGI:MGI:1924203"
                     /translation="MPVVWPTLLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKE
                     KKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPL
                     MPRLVPQTAFTVTANAVANAAVQHNASLPVPAETASKDGVSCSDEDEKPRKRRRTNSS
                     SSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPST
                     QTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITAS
                     QASLVTSSSNGNSSSTSSPISSTVAVTTVVSSTPSVVMSTVAQGVSTSAIKVASTRLP
                     SPKSLVSGPTQILAQFPKQHQQSPKQQLQQVQQQTQQPVAQPSSVSQQQQPQQSALPP
                     GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV
                     TTPTGTQATYTRPTVSPSLGRVATTPGAATYVKTTSGSIITVVPKSLATLGGKIISSN
                     IVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTLQTVP
                     AGAKPAIITATRPITKMIVTQPKGIGSAVQPAAKIIPTKIVYGQQGKTQVLIKPKPVT
                     FQATVVSEQTRQLVTETLQQASRVADASNSSAQEGKEEPQGYTDSSSSSTESSQSSQD
                     SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEK
                     LESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTVSHRSQPQQP
                     SQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGT
                     EEGEVEEMDTLDPQTGLFYRSALTQSQSTKQQKLSQPQLEQTQLQVKTLQCFQTKQKQ
                     TIHLQADQLQHKLTQMPQLSIRHQKLNPLQQEQAQPKPDAQHTQHTVVAKDRQLPTLM
                     AQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMALPSSEKQPASQVEQP
                     IITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILQMS
                     LMEAQIDTNVEHMVVDPPKKALATNVLTGEAGALPSTHVVVAGMTKCRESCSSPSAVG
                     PPLTTRKIEAAGVPTTGQFMRIQNVGQKKAEESPTEIIIQAIPQYAIPCHSSSNVVVE
                     PSGLLELNNFTSQQLDDDETAMEQDIDSSTEDGTEPSPSQSAVERS"
     exon            214..313
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            314..388
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            389..564
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            565..824
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            825..1101
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1356
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1506
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1507..1677
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..1814
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1815..1988
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1989..2187
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2188..2352
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2353..2508
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2509..2660
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2661..3221
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3222..3701
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3702..5666
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5058..5063
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /note="hexamer: TATAAA"
     regulatory      5062..5067
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /note="hexamer: AATAAG"
     polyA_site      5081
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /note="major polyA site"
     polyA_site      5085
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
     regulatory      5625..5630
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5666
                     /gene="Emsy"
                     /gene_synonym="2210018M11Rik; 2310016L09Rik"
ORIGIN      
        1 gtcgccatct tgccccttct gaggcaccgc aaacaaacct aattcctggt gtcccctagt
       61 cttggcggag gagcctttta gatgagcccc gaaaggccgg gcagggagga caagctcttt
      121 ggggctacca gacagaagca gcaatgcctg ttgtgtggcc aacccttttg gatctcagca
      181 gggatgaatg caaacggatt cttcgaaaat tggaactgga ggcatatgct ggagttatca
      241 gtgcacttcg ggcacaaggg gacctcacca aggaaaagaa agatcttctt ggagagctct
      301 caaaagtcct tagcatctca acagagcgcc accgtgctga agttcggaga gcagtaaacg
      361 atgaacggtt aacaacaatt gcacataata tgtctggacc taatagttct tcagagtggt
      421 ccatcgaagg acgtagattg gtacctctga tgcccaggct ggttccccag actgccttca
      481 ctgtaacagc gaatgctgtg gccaatgcag ctgtccagca caatgcgtcc cttcctgtgc
      541 ctgcagagac agcaagcaaa gacggcgtta gctgctcaga tgaagatgaa aaacccagaa
      601 aacgcaggcg aacaaactcc tctagctcct cccctgttgt cctcaaggaa gttccaaagg
      661 ctgttgttcc ggtctcaaag acgatcactg tgcctgtgag tggaagtccc aagatgagca
      721 acattatgca gagcattgcc aactccttac caccccatat gtcacctgtg aaaataacgt
      781 ttaccaaacc atcaacacag acaacaaaca caacaacaca gaaggttatt atagtgacca
      841 catcaccaag ttcaaccttt gtgcccaaca ttctctccaa atctcataac tatgcagcag
      901 tcactaagct tgtaccaaca tcagtcattg cctccacgac tcagaagcca cctgttgtta
      961 taactgcgtc ccaggcctct ctggtcacca gtagcagcaa tggcaacagc agttctacgt
     1021 catcacctat ttctagtaca gttgcagtaa caacggtggt atcttccaca ccgtccgtgg
     1081 tcatgtcaac agtagcacaa ggtgtatcca catcagcaat caaagtggca tcgacaagac
     1141 ttccttcccc caaaagctta gtgagtggcc ctacccagat tcttgcacag tttcctaaac
     1201 agcatcagca gtctcctaag cagcagttac agcaagtaca acaacagaca cagcagccag
     1261 tggcccagcc ttcttcagtg tctcagcagc agcagcctca gcagtcagca ttgccgcctg
     1321 gtatcaaacc taccatccag atcaaacagg agtcaggtgt taaaatcatc acacagcagg
     1381 ttcaaccaag taaaatctta cccaaaccag tgactgcaac tctacccacc agtagcaatt
     1441 ccccaattat ggtggttagc agtaatggtg caattatgac aactaaactg gtaaccactc
     1501 ctaccggtac tcaggcaacc tatacccggc caacagtgag cccatcctta ggtcgtgtgg
     1561 ctacaacccc tggagctgca acctatgtga aaactaccag tggcagcatc atcactgtag
     1621 tacccaaatc attagctacc ttgggaggca agataattag cagtaatatt gtttctggaa
     1681 cgactaccaa aatcactaca atcccaatga cttccaagcc caatgtgatt gttgtacaaa
     1741 agactacagg aaaaggaacg accattcaag gcctccctgg caaaaacgtt gtcacaacct
     1801 tgctaaatgc tggaggagaa aagactcttc agacagtgcc agctggagcc aagccagcta
     1861 taattactgc tacaagaccc atcaccaaaa tgattgtaac acagcccaaa ggaataggtt
     1921 ccgcagtaca gccagcagct aaaatcattc caacaaaaat tgtgtatgga caacaaggga
     1981 aaacacaggt tctaattaaa cccaaaccag tgacatttca agctacagtt gtcagtgaac
     2041 aaacaaggca gctggtaaca gaaacattac agcaagcatc cagggtagca gatgccagta
     2101 attcatctgc tcaggaagga aaagaggagc cacagggtta cacagacagt agttcttctt
     2161 ccacagagtc ctcccagagt tctcaagatt cccagcctgt agttcatgta attgcttccc
     2221 ggcgtcagga ttggtcagaa catgagattg caatggagac tagccccacc ataatatatc
     2281 aggatgtatc cagtgaatca caatcagcca cttcaacaat caaagctctg ttagaactcc
     2341 aacagacaac agtaaaggaa aaattggaat ctaaaccaag acaacccact attgacttga
     2401 gtcaaatggc agtacctatt cagatgaccc aggaaaagag acattctcct gagagtccat
     2461 ccattgctgt ggtagagtca gaactagttg ctgaatacat caccacggtc agccatcgct
     2521 cccagcccca acagccttcc cagccccagc ggaccctgct tcaacatgtg gctcagtcac
     2581 agactgcgac gcagacttcg gtggtagtaa agtccatccc agcgtcttcc cctggagcaa
     2641 tcacccacat catgcagcag gcattaagca gtcacaccgc ttttacgaaa cacagtgagg
     2701 aacttggaac tgaggagggt gaggttgaag agatggacac attggatcct cagacaggtc
     2761 tgttttaccg ctctgccctg acacaatcgc agtcaaccaa acagcagaaa cttagccagc
     2821 cccagctgga acagactcag ctgcaagtga aaactctgca gtgcttccag accaaacaga
     2881 agcagaccat ccacctgcag gcagaccaac tccagcacaa actcacacag atgccccagc
     2941 tctctatcag gcatcagaaa ctgaatcctc tccagcagga acaagcacag cccaagccag
     3001 atgcacagca cacacagcat actgtggtgg ccaaagacag gcagcttcct accttaatgg
     3061 cacagccccc gcaaactgta gtacaggtgc ttgccgtgaa aaccacacag cagcttccta
     3121 aactgcagca agctccgaac caaccaaaaa tctacgtgca accccaaact cctcagagcc
     3181 agatggcact cccctcttca gagaaacagc ctgcaagcca ggtggagcag ccaattataa
     3241 ctcaaggatc ctctgttaca aagataacat ttgaggggcg ccagcctccc acagttacaa
     3301 agataactgg tggcagttct gttcctaagc tgacatcacc agttacaagc atatctccca
     3361 ttcaggcctc tgagaagaca gcagtgtcag acattttgca aatgtctttg atggaagctc
     3421 agattgatac aaatgtagaa catatggtag tggatccccc aaagaaggct ctagccacca
     3481 atgtgctcac tggtgaggca ggagctctac cctccaccca tgtggtggtg gcagggatga
     3541 cgaaatgtag agagtcctgt tcaagtccat ctgctgttgg ccctccccta acgaccagaa
     3601 aaatcgaagc agcaggagtg cctacgacag gccagttcat gcgtattcag aatgtaggcc
     3661 aaaagaaagc tgaagagagc ccaacagaaa ttatcatcca ggccattccc cagtatgcta
     3721 ttccttgtca ctccagctcc aatgtggtgg tggagcccag tgggcttcta gagttgaaca
     3781 acttcaccag tcagcagcta gatgacgacg agacagccat ggagcaggac atagacagca
     3841 gcacggagga cgggactgag cccagcccct ctcagagcgc tgtagaacgg tcctagtgtg
     3901 cagacgccgg agtgcacttt agagcctgcg tggttaccaa atgtccaggg aaacttaaaa
     3961 tttgttatag taaaaaagaa aaaaaaaaaa aagaaagaaa gaaaaaagca ctttgctcat
     4021 atttaggctg gggacctaga agcattttaa caaaattaaa ctcacagagg aatgtacttt
     4081 aaaaaaaaaa aatagaaaaa gaaaaaaaaa aaagcagagg aaacgatgca ccccatggag
     4141 cccggcacct tgttggtgct aagcagcgag aagagacttt cctgtgagtg gtcctcgact
     4201 gctttccact gagcaaatac caccagagag tatgaaaagg aaaagaaagg agaatatgaa
     4261 gagtttgtat ttttgaaatg atgtatctga acagtttttc aaaaattgtg tttgtttttg
     4321 caaatccctg gagatgttga tttggctagc attttacatt tgctcagttc atgattagtt
     4381 tatgaatacc tagggaagtc ctggcattgg agtccttgct ggacggtaga catcagtcag
     4441 gttgctgcct gggcagtttg gggtggcttg tacatgtgct ccttggttgt atactaattt
     4501 attgtggagt tccacacttg cctatttatt taatgtaaat gttttgaagc aggccgaatc
     4561 ccttttccta catgtcctgg gaagctggat ccctggcctt cccaccttcc caccccctca
     4621 ccccccttta agaagacgga ttagagaaga tttggtccgg aagcagagga aaagacattt
     4681 ctagcccaaa ggaaatgctc agtggtgttc ctgaaaatga gctctgctca ttggatgctt
     4741 tctcgacacc gacgttgcac acccgtgttg gactgagact ttgaaaacaa ctttgactta
     4801 ctttggttta aatcctttga aatgtatgaa aatgttcact tacagttcta aatgtaatgt
     4861 ttttaagttt ttaatttttt agggtgcagt ttgtttacgt gcaggtgtgg tcttgtgatt
     4921 gctgtctatc acaagtagag tgaagggtaa gggatgggag ggtaagaatt ttgacaagct
     4981 gtggcaaagg aaactatacc tttcattttt aaaaagtgta aatagaaaag tttttaacgg
     5041 ttttatatga atttcactat aaataagcat tttaagactg acaaatgttg aactgtatat
     5101 acatttatca acttaactgc ccagtttttg gtgctgaagt actgtaagta gaatttatca
     5161 gtagcgtcct aatttctgtg tctacacctg gggagaagct gtgatgctgt agttaatcaa
     5221 cttacacaag tgcttacact tgtgtaactt acactgataa tctcggcagg agcatccctg
     5281 agacacctac cttgtggtgg tgattgtccc catttctact aggtgaaagt tactcaccca
     5341 tagatggagc tcttggatag cattttattg tacaaatgtg tttcaacaac cactttgtga
     5401 ctgttcctag ctaaggggaa atttaacttc tcttgggtca tagacatctt taagaagctg
     5461 attattctat gaactctctc accaaaaaaa tacacatgcc aggacacgtg ttaagatttt
     5521 gcatacaatt ttagggactt aagaactccc aagaccatcc atgtattcca ggttaagcct
     5581 tctgttatgg tcagctcatt acttacaggt gtaagttttt atcaaataaa atatcttttg
     5641 gatacacatg gatcaggaaa taagaa
//
