LOCUS       NM_033146                838 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus ER membrane protein complex subunit 9 (Emc9),
            transcript variant 1, mRNA.
ACCESSION   NM_033146
VERSION     NM_033146.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Guna,A., Volkmar,N., Christianson,J.C. and Hegde,R.S.
  TITLE     The ER membrane protein complex is a transmembrane domain insertase
  JOURNAL   Science 359 (6374), 470-473 (2018)
   PUBMED   29242231
REFERENCE   2  (bases 1 to 838)
  AUTHORS   Yawata,M., Murata,S., Tanaka,K., Ishigatsubo,Y. and Kasahara,M.
  TITLE     Nucleotide sequence analysis of the approximately 35-kb segment
            containing interferon-gamma-inducible mouse proteasome activator
            genes
  JOURNAL   Immunogenetics 53 (2), 119-129 (2001)
   PUBMED   11345588
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC174678.2.
            
            On Mar 23, 2023 this sequence version replaced NM_033146.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU560347.1, AB054001.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-371               AC174678.2         75883-76253
            372-448             AC174678.2         76410-76486
            449-518             AC174678.2         79040-79109
            519-613             AC174678.2         79190-79284
            614-838             AC174678.2         79422-79646
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 28.19 cM"
     gene            1..838
                     /gene="Emc9"
                     /gene_synonym="1500005A01Rik; Cgi112; Fam158a"
                     /note="ER membrane protein complex subunit 9"
                     /db_xref="GeneID:85308"
                     /db_xref="MGI:MGI:1934682"
     exon            1..371
                     /gene="Emc9"
                     /gene_synonym="1500005A01Rik; Cgi112; Fam158a"
                     /inference="alignment:Splign:2.1.0"
     CDS             174..794
                     /gene="Emc9"
                     /gene_synonym="1500005A01Rik; Cgi112; Fam158a"
                     /note="isoform 1 is encoded by transcript variant 1;
                     UPF0172 protein FAM158A; family with sequence similarity
                     158, member A"
                     /codon_start=1
                     /product="ER membrane protein complex subunit 9 isoform 1"
                     /protein_id="NP_149158.1"
                     /db_xref="CCDS:CCDS27117.1"
                     /db_xref="GeneID:85308"
                     /db_xref="MGI:MGI:1934682"
                     /translation="MGEVEISARAYGKMCLHASRYPHAAVNGLLLAPATGSGECLCLT
                     DCVPLFHSHLALSVMLEVALNQVDVWGAQAGLVVAGYYHANAVLDDQSPGPLALKIAG
                     RIAEFFPRAVLIMLDNKKLVTRPRVPPVIVLENQGLQWVPKDKNLVMWRDWEESRQMV
                     GALLEGRAHQHLVDFDCHLDDIRQDWTNQRLNTQITQWSGSTDGNA"
     exon            372..448
                     /gene="Emc9"
                     /gene_synonym="1500005A01Rik; Cgi112; Fam158a"
                     /inference="alignment:Splign:2.1.0"
     exon            449..518
                     /gene="Emc9"
                     /gene_synonym="1500005A01Rik; Cgi112; Fam158a"
                     /inference="alignment:Splign:2.1.0"
     exon            519..613
                     /gene="Emc9"
                     /gene_synonym="1500005A01Rik; Cgi112; Fam158a"
                     /inference="alignment:Splign:2.1.0"
     exon            614..838
                     /gene="Emc9"
                     /gene_synonym="1500005A01Rik; Cgi112; Fam158a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      814..819
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Emc9"
                     /gene_synonym="1500005A01Rik; Cgi112; Fam158a"
                     /note="hexamer: AATAAA"
     polyA_site      838
                     /gene="Emc9"
                     /gene_synonym="1500005A01Rik; Cgi112; Fam158a"
                     /note="major polyA site"
ORIGIN      
        1 gcagttggac cgaattctac cttgctaggg acgggctgca gagagtggtc gccaggcgtc
       61 aggggcatct tacacccaag tgagaaggga ggcacagggc gaggccaagc tcgcctctgg
      121 tggtcaggga gccgccttag tgggggttcg ggtgccggca ggccccgctc gctatggggg
      181 aggtggagat ctccgcccga gcctacggga agatgtgtct gcacgcctct cggtacccac
      241 acgctgctgt caacgggttg ttgctggctc ccgcgacggg gtccggagaa tgcctctgcc
      301 tcaccgactg tgtgcccctc ttccacagcc atctggcctt gtccgtcatg ctggaggtcg
      361 cgctcaacca ggtggatgtg tggggcgcgc aggccggtct ggtggtagct gggtactacc
      421 atgccaatgc ggttttggat gaccagagcc ccgggcctct ggccttgaaa atcgctgggc
      481 gaattgcaga attcttcccc agggcagtgc ttattatgct ggataataag aaattggtga
      541 ctcggcctcg tgtacctcca gtcattgtcc tggagaacca gggtcttcag tgggtgccca
      601 aggacaagaa cttagtgatg tggagagatt gggaggagtc acgacagatg gtgggtgcgc
      661 tgttggaggg ccgggctcac cagcatcttg tggactttga ctgccatctt gatgacattc
      721 ggcaggactg gaccaaccag cggcttaaca ctcaaatcac tcaatggagt ggttccacag
      781 atggaaatgc ctaagtcaga agggtccaca tacaataaag acatgggctg gtgggcaa
//
