LOCUS       NP_848851                293 aa            linear   ROD 30-APR-2024
DEFINITION  ELMO domain-containing protein 2 [Mus musculus].
ACCESSION   NP_848851
VERSION     NP_848851.3
DBSOURCE    REFSEQ: accession NM_178736.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 293)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 293)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 293)
  AUTHORS   Turn,R.E., Linnert,J., Gigante,E.D., Wolfrum,U., Caspary,T. and
            Kahn,R.A.
  TITLE     Roles for ELMOD2 and Rootletin in ciliogenesis
  JOURNAL   Mol Biol Cell 32 (8), 800-822 (2021)
   PUBMED   33596093
  REMARK    GeneRIF: Roles for ELMOD2 and Rootletin in ciliogenesis.
REFERENCE   4  (residues 1 to 293)
  AUTHORS   Turn,R.E., East,M.P., Prekeris,R. and Kahn,R.A.
  TITLE     The ARF GAP ELMOD2 acts with different GTPases to regulate
            centrosomal microtubule nucleation and cytokinesis
  JOURNAL   Mol Biol Cell 31 (18), 2070-2091 (2020)
   PUBMED   32614697
  REMARK    GeneRIF: The ARF GAP ELMOD2 acts with different GTPases to regulate
            centrosomal microtubule nucleation and cytokinesis.
REFERENCE   5  (residues 1 to 293)
  AUTHORS   Zhou,C.X., Shi,L.Y., Li,R.C., Liu,Y.H., Xu,B.Q., Liu,J.W., Yuan,B.,
            Yang,Z.X., Ying,X.Y. and Zhang,D.
  TITLE     GTPase-activating protein Elmod2 is essential for meiotic
            progression in mouse oocytes
  JOURNAL   Cell Cycle 16 (9), 852-860 (2017)
   PUBMED   28324667
  REMARK    GeneRIF: Elmod2 is the GTPase-activating protein essential to
            meiosis progression of mouse oocytes, most likely by regulating
            mitochondrial dynamics.
REFERENCE   6  (residues 1 to 293)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK084950.1 and AC122890.4.
            
            On Jan 7, 2010 this sequence version replaced NP_848851.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036746.1, BC079654.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 39.72 cM"
     Protein         1..293
                     /product="ELMO domain-containing protein 2"
                     /note="ELMO domain containing 2"
                     /calculated_mol_wt=34616
     Region          110..268
                     /region_name="ELMO_CED12"
                     /note="ELMO/CED-12 family; pfam04727"
                     /db_xref="CDD:461411"
     CDS             1..293
                     /gene="Elmod2"
                     /gene_synonym="9830169G11Rik"
                     /coded_by="NM_178736.5:144..1025"
                     /db_xref="CCDS:CCDS22450.1"
                     /db_xref="GeneID:244548"
                     /db_xref="MGI:MGI:2445165"
ORIGIN      
        1 mfvslweffy ghffrfwmkw llrqmtgkce lqrifdtygg aqrtyriens ltysknkvlq
       61 natrvaqsel drcianimke knicsekdts fqicmrtcll qitgykqlyh dvenvrkkpy
      121 dsanaqhekm llklwsllmp tkkltarisk qwadigfqgd dpktdfrgmg ilglinlvyf
      181 senytseahq ilsrsnhpkl gysyaivgin ltemaysllk sealklhlyn fvpgvptmeh
      241 fhqfycylvy efdkfwleee pesimyfnly rekfherikg llmdcnavlt lkt
//
