LOCUS       NM_080288               5576 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus engulfment and cell motility 1 (Elmo1), transcript
            variant 3, mRNA.
ACCESSION   NM_080288
VERSION     NM_080288.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5576)
  AUTHORS   Li,C., Zhang,M., Du,Y., Liu,S., Li,D., Zhang,S., Ji,F., Zhang,J.
            and Jiao,J.
  TITLE     Compromised cell competition exhausts neural stem cells pool
  JOURNAL   Cell Prolif 57 (12), e13710 (2024)
   PUBMED   39010274
REFERENCE   2  (bases 1 to 5576)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 5576)
  AUTHORS   Sharma,A., Achi,S.C., Ibeawuchi,S.R., Anandachar,M.S.,
            Gementera,H., Chaudhury,U., Usmani,F., Vega,K., Sayed,I.M. and
            Das,S.
  TITLE     The crosstalk between microbial sensors ELMO1 and NOD2 shape
            intestinal immune responses
  JOURNAL   Virulence 14 (1), 2171690 (2023)
   PUBMED   36694274
  REMARK    GeneRIF: The crosstalk between microbial sensors ELMO1 and NOD2
            shape intestinal immune responses.
REFERENCE   4  (bases 1 to 5576)
  AUTHORS   Yu,S., Geng,X., Liu,H., Zhang,Y., Cao,X., Li,B. and Yan,J.
  TITLE     ELMO1 Deficiency Reduces Neutrophil Chemotaxis in Murine
            Peritonitis
  JOURNAL   Int J Mol Sci 24 (9), 8103 (2023)
   PUBMED   37175809
  REMARK    GeneRIF: ELMO1 Deficiency Reduces Neutrophil Chemotaxis in Murine
            Peritonitis.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5576)
  AUTHORS   Tran,V., Nahle,S., Robert,A., Desanlis,I., Killoran,R.,
            Ehresmann,S., Thibault,M.P., Barford,D., Ravichandran,K.S.,
            Sauvageau,M., Smith,M.J., Kmita,M. and Cote,J.F.
  TITLE     Biasing the conformation of ELMO2 reveals that myoblast fusion can
            be exploited to improve muscle regeneration
  JOURNAL   Nat Commun 13 (1), 7077 (2022)
   PUBMED   36400788
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5576)
  AUTHORS   Grimsley,C.M., Lu,M., Haney,L.B., Kinchen,J.M. and
            Ravichandran,K.S.
  TITLE     Characterization of a novel interaction between ELMO1 and ERM
            proteins
  JOURNAL   J Biol Chem 281 (9), 5928-5937 (2006)
   PUBMED   16377631
REFERENCE   7  (bases 1 to 5576)
  AUTHORS   Katoh,H., Fujimoto,S., Ishida,C., Ishikawa,Y. and Negishi,M.
  TITLE     Differential distribution of ELMO1 and ELMO2 mRNAs in the
            developing mouse brain
  JOURNAL   Brain Res 1073-1074, 103-108 (2006)
   PUBMED   16443196
REFERENCE   8  (bases 1 to 5576)
  AUTHORS   Kakoki,M., Tsai,Y.S., Kim,H.S., Hatada,S., Ciavatta,D.J.,
            Takahashi,N., Arnold,L.W., Maeda,N. and Smithies,O.
  TITLE     Altering the expression in mice of genes by modifying their 3'
            regions
  JOURNAL   Dev Cell 6 (4), 597-606 (2004)
   PUBMED   15068798
REFERENCE   9  (bases 1 to 5576)
  AUTHORS   Papin,J. and Subramaniam,S.
  TITLE     Bioinformatics and cellular signaling
  JOURNAL   Curr Opin Biotechnol 15 (1), 78-81 (2004)
   PUBMED   15102471
  REMARK    Review article
REFERENCE   10 (bases 1 to 5576)
  AUTHORS   Gumienny,T.L., Brugnera,E., Tosello-Trampont,A.C., Kinchen,J.M.,
            Haney,L.B., Nishiwaki,K., Walk,S.F., Nemergut,M.E., Macara,I.G.,
            Francis,R., Schedl,T., Qin,Y., Van Aelst,L., Hengartner,M.O. and
            Ravichandran,K.S.
  TITLE     CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is
            required for phagocytosis and cell migration
  JOURNAL   Cell 107 (1), 27-41 (2001)
   PUBMED   11595183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC126555.3, AC124183.4, AC165346.4, AC132085.3, AC153143.4 and
            AC124751.4.
            
            On Apr 27, 2011 this sequence version replaced NM_080288.1.
            
            Transcript Variant: This variant (3) represents the longer
            transcript and encodes the longer isoform (3).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK220253.1, SRR7652917.851623.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-265               AC126555.3         47434-47698         c
            266-416             AC124183.4         107968-108118
            417-457             AC124183.4         130748-130788
            458-530             AC124183.4         131753-131825
            531-581             AC124183.4         164187-164237
            582-751             AC124183.4         173618-173787
            752-787             AC124183.4         184171-184206
            788-887             AC124183.4         197134-197233
            888-1039            AC124183.4         203426-203577
            1040-1118           AC124183.4         205526-205604
            1119-1169           AC124183.4         209334-209384
            1170-1292           AC124183.4         210505-210627
            1293-1424           AC124183.4         212976-213107
            1425-1529           AC165346.4         29467-29571         c
            1530-1638           AC132085.3         87375-87483         c
            1639-1775           AC132085.3         10959-11095         c
            1776-1939           AC153143.4         7889-8052           c
            1940-2052           AC153143.4         19-131              c
            2053-2160           AC124751.4         64372-64479         c
            2161-2243           AC124751.4         56972-57054         c
            2244-2321           AC124751.4         46441-46518         c
            2322-5576           AC124751.4         38345-41599         c
FEATURES             Location/Qualifiers
     source          1..5576
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 7.21 cM"
     gene            1..5576
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /note="engulfment and cell motility 1"
                     /db_xref="GeneID:140580"
                     /db_xref="MGI:MGI:2153044"
     exon            1..265
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            266..416
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     CDS             339..2522
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /note="isoform 3 is encoded by transcript variant 3;
                     engulfment and cell motility protein 1; engulfment and
                     cell motility 1, ced-12 homolog"
                     /codon_start=1
                     /product="engulfment and cell motility protein 1 isoform
                     3"
                     /protein_id="NP_525027.1"
                     /db_xref="CCDS:CCDS26265.1"
                     /db_xref="GeneID:140580"
                     /db_xref="MGI:MGI:2153044"
                     /translation="MPPPSDIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLA
                     NHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLE
                     ALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLT
                     AFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQK
                     VAQEITIGQLIPHLQGTDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRYIIL
                     THVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDA
                     ESEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQ
                     DAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDR
                     SFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQN
                     LSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLN
                     ARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPH
                     MKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLT
                     RNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN"
     exon            417..457
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            458..530
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            531..581
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            582..751
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            752..787
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            788..887
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1039
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1118
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1169
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            1170..1292
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1424
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..1529
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1638
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            1639..1775
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            1776..1939
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            1940..2052
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            2053..2160
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            2161..2243
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            2244..2321
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     exon            2322..5576
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3729..3734
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /note="hexamer: AATAAA"
     polyA_site      3751
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /note="major polyA site"
     regulatory      5557..5562
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
                     /note="hexamer: AATAAA"
     polyA_site      5576
                     /gene="Elmo1"
                     /gene_synonym="6330578D22Rik; C230095H21Rik; CED-12"
ORIGIN      
        1 agatgcaaga tgtgtctctg gccagcagga ggaaggaaga ggaagtgaga gcagcggcag
       61 ccggcggcag cggccagcga cccgagtcta agtgcgtgcg ttcgggcagc ggcagcgggc
      121 gaggatgggc acgagataga ggcagagcca ccgccgtccg cgcctccgag agcggcgaca
      181 gagcctcggg caccggtcta cgtctcctgc cccggcgctc cggcctctgg gaaccctcgt
      241 tgcggcgtcc tgagaccccg ggcaggttta gacacgtgtg ccggtccacg cggtaggacc
      301 tccgtttcta cctgctttgt acttcctcca gtcacacaat gccgccgcct tcggacatcg
      361 tgaaggtggc catagaatgg cctggcgcct accctaaact catggagatt gaccagaaaa
      421 agccactgtc tgccattata aaggaagtct gtgatgggtg gtctcttgcc aaccatgaat
      481 attttgcact gcagcacgct gatagttcaa acttctacat cacagaaaag aatcgcaacg
      541 aaataaaaaa tggcacgatc cttcgattaa ccacatctcc agctcagaat gcccagcagc
      601 tccatgaacg aatacagtca tcaagtatgg atgccaagtt ggaagccctg aaggacttgg
      661 ccagcctctc ccgggatgtt acctttgctc aggagttcat aaacctggat ggcatctcac
      721 ttctcactca gatggtggaa agtggcactg aacgatacca gaagttgcag aagattatga
      781 agccctgctt tggagacatg ctgtccttca ctctcacagc ctttgtggag ttgatggacc
      841 acggcattgt atcatgggat acattctcag tggccttcat taagaagata gccagctttg
      901 tgaacaagtc tgccatagac atctcaatcc tccagcggtc cttggccatt ctggagtcaa
      961 tggttctcaa cagtcatgac ctctaccaaa aggtagccca ggagatcacc attggccaac
     1021 tcattcctca tcttcagggg acagaccaag aaatacaaac ttacaccatt gctgtaatca
     1081 acgcactttt cctcaaagct cctgatgaga ggagacagga gatggcgaat attttggctc
     1141 agaagcagct gcgctacatc attttaacac atgtcatccg agcacagcgg gccatcaaca
     1201 atgagatggc acaccagtta tatgttctcc aagtgctgac ctttaacctt ctggaagaca
     1261 ggatgatgac taagatggac ccccaggacc aggcccaaag ggacatcata tttgaacttc
     1321 gaagaattgc tttcgatgca gagtcagaac ctaataacag cagtggcagc atggagaaac
     1381 gcaagtccat gtacactcgg gattataaaa aacttggctt cattaatcac gtcaatcctg
     1441 ccatggactt cacacagacc cctcctggga tgctggctct ggacaacatg ctgtatttcg
     1501 ctaagcacca ccaggatgca tacatccgga tcgtgctaga gaacagcagc cgagaagata
     1561 aacatgagtg ccccttcggc cgcagcagta tagagctgac caagatgctg tgtgagatcc
     1621 tcaaagtggg cgagctgcct agtgagacct gcaacgactt tcacccgatg ttcttcaccc
     1681 atgacagatc ttttgaggaa ttcttctgca tttgcattca actcctgaac aaaacatgga
     1741 aggaaatgag ggcaacatct gaagacttca acaaggtaat gcaggtggtg aaggagcagg
     1801 ttatgagagc gcttacaacc aagcctagtt ccctggacca gttcaaaagc aagctgcaaa
     1861 acctgagcta caccgagatc ctgaaaatcc gccagtctga gaggatgaac caggaagatt
     1921 tccagtctcg cccgattttg gaactaaagg agaagatcca gccagaaatc ttagagctga
     1981 ttaaacagca gcgcctgaac cgccttgtgg aagggacctg ctttaggaaa ctcaatgctc
     2041 gccggagaca agacaagttt tggtattgtc ggctttcacc aaatcacaag gtcttacatt
     2101 atggcgactt ggaagagagc ccccaaggag aagtgcccca cgattccctg caggacaaat
     2161 tgccggtggc agatatcaaa gcagtggtga cgggaaagga ctgccctcat atgaaagaga
     2221 aaggtgccct taaacaaaac aaggaggtgc ttgaacttgc tttctccatc ttatacgact
     2281 caaattgcca actgaacttc attgctcctg ataagcatga gtactgcatc tggacagatg
     2341 ggctgaatgc actgcttggg aaggacatga tgagtgacct gacacgcaat gacctggaca
     2401 ccctgctgag catggagatc aagcttcgcc tgctggacct ggaaaacatc cagatcccgg
     2461 atgcacctcc gcctatcccc aaggaaccta gcaactatga ctttgtctat gactgtaact
     2521 gaactggctg cacccagacg cattcctccc aaactggaag atctagctat cagcagagag
     2581 cagagcaaac acatccacat gctgcaactg cccttgggtg gaggggaagc tgcagcttcc
     2641 tttggcctca tttttaaccc tagcgccacc cccccccccc atcttctctg gcatctcacc
     2701 ttctacttca atctatttcc tgacgcagtg ttttagatcc tctaccattg ctacagctca
     2761 gcgatgggtc atgagcaaaa gtcaccacta gtaacagtcg aagagtcctc tcattatatc
     2821 cagctatggg catttccttc cttccttcct tccttccttc cttccttcct tccttccttc
     2881 cttccttcct tccttcattc ttgcctggag taggaaagcc agttagcccc aagctgcccc
     2941 atatttgctc accaaaccaa gagaaattcc taaggccagg gttggataaa atagctctgc
     3001 tactggatta gaagaccaaa ggcctcctac cccttctctc tagggtcacc tcacaccatc
     3061 agctctatgt gagttgagat tgctttcaca ttgcctctct ctccctttcc tgccttggcc
     3121 ttgctctggt ccactttggt ctcacttgta gcagcagcat cctcattgta gttgtctaca
     3181 gcatcaggtc tcccaaactg tccacagagt ccatgcctgt tccttgtctg cactgtgacc
     3241 atgaccaatc cctctatcac actgtctagt cttgggcttc ctctctttgc cccagcccag
     3301 gcctgccttc ttcatttctt cgagctccca gcccttagca gaaagcacaa atgaagtcag
     3361 tagtcctgct ccatctctga taaactaaac ctaaccgccc ctaaggcggc tgttgctatc
     3421 taacagttcc gtgtgacctt ctctctgggg ctcctgctac agcccaggtt ttccagggtg
     3481 gtcaagctgt cagacatcca agtttacatc gttgtaatta ttataggtct ttaaatttta
     3541 caagggtttg gggttatttt gttttgtttt gttggctttg tttttgtata aaagagtcta
     3601 acattttttg ccaaacagat atatatttaa tgaagagata cataaatgtg tgtactttcc
     3661 agcttttttt taattatttt aatcccaaac atcttcctga gagtaacact cccttaaaca
     3721 tgctgtggaa taaaattaaa tgtgaagagt tggggagctg gtgttttgat ttagtaatgt
     3781 gggcgcttgc tactccagca tatccatcac ctgggaattt gttagagatg caaagcagac
     3841 agcccctcca gacttctgaa ccacgatgtt tgagtaggtg ttcatttggg aagcactgat
     3901 cgtgagctct aaagcattgc cgatatcatt tctaggatgc acaccccaac tcaccaagga
     3961 aatgagactc actgtacaaa aatatgatct attcctttta tattgctgct tcctcggcat
     4021 actttcccat tattgtctcc ttaccatttc atgacttata gagccagtcc aattaaagac
     4081 actactgaca ccaaggggac atgttgaacc acggaaaaag aatacaaacc tacacacctg
     4141 aaatcagtta cgccaaagcc aatcttactg tgaattaata agttcccaac agagcacaac
     4201 agagatttct tcttaagtca gctcccctac aaatgtcata tggatcgtaa gctctaaggg
     4261 ctgggaggga tgacagaacc ccatgcagtg cagctaagcc actctgaact ggcagccaag
     4321 atctagatac atgcaggtga ctgctctttg tggctgtcaa gatggtcaat tacaggttgg
     4381 cctgggctcc agtgacatgg tccagagcac tccataaatt gcaaaatcca tagtcattca
     4441 caggggtcat tctttccact agagtgccca catcggagtg ttaggctgac atttcctcca
     4501 tccttaagct tggatcttat taacatgcat gcccttcctg atggagtcat ctactgttct
     4561 acctgctgtg tgataagtta gataaaagga agtggataga ggcagagcac ttttcacttc
     4621 aaagtttaag agatgcacct cctggggcct ggatgggaag aattcatctc ctggtattcc
     4681 tactttggcc cataaattag aaatttgtgg ggacattttt tttctttttc atgtatatat
     4741 ataatacttg tgcacaagtg tgggacagca tagtgttttg gtccatgtta cactgggtag
     4801 tgagaaagtc tctctattgc catgaccatt tatcatatct atatagtgaa tacactggaa
     4861 atcccctctt ctagtgatct cgagatatac aatcttgtga actgtatcca cacactcctg
     4921 cactgtagga ccccagaatg tagccctcct aactatcatt gtacccactg tataccccat
     4981 gtgctctctc cagcctccag tattgactcc ttattcagct acaggattcc atggtgggtg
     5041 ttctgcttac tgtccttgag aatatttcat ttaataatgt cttccagtcc cacccgaggt
     5101 gttgaaagtg actgtatttt atctttttat ggctccataa tagtccattg tgtacccaca
     5161 ccaccattta ttttttcact cacctgttgc taggcactga agtagatccc acatccccag
     5221 gttttgtgaa tactgctgca gtaaatatga gtacaggttc ctcctggtga gcttttgtat
     5281 ggaagacaca ccttttcata gactgacagc gtcttaagga cacgctctca ttgttctgca
     5341 tttcttttat tttgtggcaa ggtggggaag gatggttgcc catattcaac atctcaccta
     5401 tttcccaagg ctgcttaaga catttcccac acacattgag acccgtgcct caagttggat
     5461 acttctggcg tcaactgtcc aagccccatg tagtgcaaac aagaatcctg tttatcatga
     5521 agtccaagtt ctgttctcca atctggcttt atctgaaata aaaaattgta tctgaa
//
