LOCUS       NM_007920               4232 bp    mRNA    linear   ROD 01-JAN-2023
DEFINITION  Mus musculus E74 like ETS transcription factor 1 (Elf1), transcript
            variant 1, mRNA.
ACCESSION   NM_007920
VERSION     NM_007920.4
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4232)
  AUTHORS   Zhang L, Li X, Feng X, Berkman T, Ma R, Du S, Wu S, Huang C,
            Amponsah A, Bekker A and Tao YX.
  TITLE     E74-like factor 1 contributes to nerve trauma-induced nociceptive
            hypersensitivity through transcriptionally activating matrix
            metalloprotein-9 in dorsal root ganglion neurons
  JOURNAL   Pain 164 (1), 119-131 (2023)
   PUBMED   35507368
  REMARK    GeneRIF: E74-like factor 1 contributes to nerve trauma-induced
            nociceptive hypersensitivity through transcriptionally activating
            matrix metalloprotein-9 in dorsal root ganglion neurons.
REFERENCE   2  (bases 1 to 4232)
  AUTHORS   Kumazoe M, Yamashita M, Nakamura Y, Takamatsu K, Bae J, Yamashita
            S, Yamada S, Onda H, Nojiri T, Kangawa K and Tachibana H.
  TITLE     Green Tea Polyphenol EGCG Upregulates Tollip Expression by
            Suppressing Elf-1 Expression
  JOURNAL   J Immunol 199 (9), 3261-3269 (2017)
   PUBMED   28954885
  REMARK    GeneRIF: Green Tea Polyphenol EGCG Upregulates Tollip Expression by
            Suppressing Elf-1 Expression
            Erratum:[J Immunol. 2018 Feb 23;:. PMID: 29475984]
REFERENCE   3  (bases 1 to 4232)
  AUTHORS   Parashar K, Kopping E, Frank D, Sampath V, Thanassi DG and Carpino
            N.
  TITLE     Increased Resistance to Intradermal Francisella tularensis LVS
            Infection by Inactivation of the Sts Phosphatases
  JOURNAL   Infect Immun 85 (9), e00406-17 (2017)
   PUBMED   28630061
  REMARK    GeneRIF: Herein, the authors demonstrate that mice lacking Sts
            expression are significantly resistant to infection by the live
            vaccine strain of Francisella tularensis.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4232)
  AUTHORS   Brooke-Bisschop T, Savory JGA, Foley T, Ringuette R and Lohnes D.
  TITLE     Essential roles for Cdx in murine primitive hematopoiesis
  JOURNAL   Dev Biol 422 (2), 115-124 (2017)
   PUBMED   28065741
REFERENCE   5  (bases 1 to 4232)
  AUTHORS   Ohta Y, Okabe T, Larmour C, Di Rocco A, Maijenburg MW, Phillips A,
            Speck NA, Wakitani S, Nakamura T, Yamada Y, Enomoto-Iwamoto M,
            Pacifici M and Iwamoto M.
  TITLE     Articular cartilage endurance and resistance to osteoarthritic
            changes require transcription factor Erg
  JOURNAL   Arthritis Rheumatol 67 (10), 2679-2690 (2015)
   PUBMED   26097038
REFERENCE   6  (bases 1 to 4232)
  AUTHORS   Blagosklonny MV.
  TITLE     A node between proliferation, apoptosis, and growth arrest
  JOURNAL   Bioessays 21 (8), 704-709 (1999)
   PUBMED   10440867
  REMARK    Review article
REFERENCE   7  (bases 1 to 4232)
  AUTHORS   Araki K, Imaizumi T, Sekimoto T, Yoshinobu K, Yoshimuta J, Akizuki
            M, Miura K, Araki M and Yamamura K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   8  (bases 1 to 4232)
  AUTHORS   Serdobova I, Pla M, Reichenbach P, Sperisen P, Ghysdael J, Wilson
            A, Freeman J and Nabholz M.
  TITLE     Elf-1 contributes to the function of the complex interleukin
            (IL)-2-responsive enhancer in the mouse IL-2 receptor alpha gene
  JOURNAL   J Exp Med 185 (7), 1211-1221 (1997)
   PUBMED   9104808
REFERENCE   9  (bases 1 to 4232)
  AUTHORS   Davis JN and Roussel MF.
  TITLE     Cloning and expression of the murine Elf-1 cDNA
  JOURNAL   Gene 171 (2), 265-269 (1996)
   PUBMED   8666284
REFERENCE   10 (bases 1 to 4232)
  AUTHORS   Gunther CV and Graves BJ.
  TITLE     Identification of ETS domain proteins in murine T lymphocytes that
            interact with the Moloney murine leukemia virus enhancer
  JOURNAL   Mol Cell Biol 14 (11), 7569-7580 (1994)
   PUBMED   7935472
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC057134.1, AK132456.1 and AK142807.1.
            
            [WARNING] On Jun 2, 2023 this sequence was replaced by NM_007920.5.
            
            On Nov 5, 2013 this sequence version replaced NM_007920.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer protein (isoform 1). Variants 1
            and 2 encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057134.1, SRR7652917.772442.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3405              BC057134.1         1-3405
            3406-4216           AK132456.1         3060-3870
            4217-4232           AK142807.1         3277-3292
FEATURES             Location/Qualifiers
     source          1..4232
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14"
     gene            1..4232
                     /gene="Elf1"
                     /gene_synonym="Elf-1; mElf-1; p70; Sts1"
                     /note="E74 like ETS transcription factor 1"
                     /db_xref="GeneID:13709"
                     /db_xref="MGI:MGI:107180"
     exon            1..444
                     /gene="Elf1"
                     /gene_synonym="Elf-1; mElf-1; p70; Sts1"
                     /inference="alignment:Splign:2.1.0"
     exon            445..744
                     /gene="Elf1"
                     /gene_synonym="Elf-1; mElf-1; p70; Sts1"
                     /inference="alignment:Splign:2.1.0"
     CDS             673..2511
                     /gene="Elf1"
                     /gene_synonym="Elf-1; mElf-1; p70; Sts1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ETS-related transcription factor Elf-1; E74-like factor 1"
                     /codon_start=1
                     /product="ETS-related transcription factor Elf-1 isoform
                     1"
                     /protein_id="NP_031946.1"
                     /db_xref="CCDS:CCDS27301.1"
                     /db_xref="GeneID:13709"
                     /db_xref="MGI:MGI:107180"
                     /translation="MAAVVQQNDLVFEFASNGMEDEQQLGDPAIFPAVIVEHVPGADI
                     LNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHNGDETIETIEAA
                     EALLNIDSPSPPVLDEKQINNNIFSSSEDDIVAPITHVSVTLDGIPEVMETQQVQETN
                     ADSPGASSPEQRKRKKGRKTKPPRPDSPTTTPNISVKKKNKDGKGNTIYLWEFLLALL
                     QDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGI
                     LAKVEGQRLVYQFKEMPKDLIYIDDEDPSSSIESSDQSLSSTTASSRNQANRSRVSSS
                     PGIKGGAATILKPGNSKAANPKDPVEVGQPSEVLRTVQPSQAPYPTQLFRTVHVVQPV
                     QAVPEEATIASTMQEEAANSSVPSIRTIQASTQVPVVVSPGNQQLHTVTVPLTTVIAS
                     IDPSSGAGSQKFILQTIPSSQPMTVLKENVMLQSQKPGSPSIVLSPTQVQQVLTSNVQ
                     SICNGAGSVASAPSFSATTPVVTFSRSSQLVAHPPGTVITSVIKAQETKTLKQEVEKK
                     AEDDLNEDAEKSAQQPQPYVMVLSSSNGFSSQVAVKQNELLEPNSF"
     exon            745..925
                     /gene="Elf1"
                     /gene_synonym="Elf-1; mElf-1; p70; Sts1"
                     /inference="alignment:Splign:2.1.0"
     exon            926..1036
                     /gene="Elf1"
                     /gene_synonym="Elf-1; mElf-1; p70; Sts1"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1201
                     /gene="Elf1"
                     /gene_synonym="Elf-1; mElf-1; p70; Sts1"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1285
                     /gene="Elf1"
                     /gene_synonym="Elf-1; mElf-1; p70; Sts1"
                     /inference="alignment:Splign:2.1.0"
     exon            1286..1478
                     /gene="Elf1"
                     /gene_synonym="Elf-1; mElf-1; p70; Sts1"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1925
                     /gene="Elf1"
                     /gene_synonym="Elf-1; mElf-1; p70; Sts1"
                     /inference="alignment:Splign:2.1.0"
     exon            1926..4232
                     /gene="Elf1"
                     /gene_synonym="Elf-1; mElf-1; p70; Sts1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggagccgc gggccccgag cgtccgaccc aggctccatc ccgcggtcct cacgcctccc
       61 gggatccaga acctccactc ccgagctggc tcgcagccga gaggctcgat cgcctccccc
      121 cagccccggc cgcacgccgc cgttcccaca gccggcgccg ccctcggctt tgccggcttg
      181 cccgcccgct ctgtgaccgg ggagcagccc gggacctgac ggctgagaaa gaaaggcgca
      241 gccgcccgtt ccgggagcgc acggggcgcc cggcttcggc tcagaacttt ccaggggcgc
      301 gcaccggccc cgctcctccc ccccgccacg cccgcgcgct ccgccgggct cgtgcccgcg
      361 cgtggggcag cggccgcggg ggcggcttcg gcggcgcgag ttgcagcaga gtggctgagt
      421 ggtagcggcg ctgacgctag tcagggacaa gaagacctag tgaatgattt cagaaaacgt
      481 gcctgttttc ttagaatgtc aatgcagcaa gcaggtctga aggactcctt tcaccgaaga
      541 gcgtcttgtc tgcagtaact tcacagacct gcctgagagg ctcttcccaa actccactgc
      601 accctacctg ctgctccaga ctggaagctg cttaggcctt ttctcatgtg gatctaaggg
      661 gaatgcttta ctatggctgc tgttgtccaa cagaacgacc tagtgtttga atttgcaagt
      721 aacggcatgg aggacgagca gcagcttggt gatcctgcta tatttcctgc tgttattgtg
      781 gaacatgttc ctggtgctga tattctcaat agttatgctg gtctagcttg tgtggaagag
      841 cctaatgaca tgattactga gagctcattg gatgttgctg aagaagaaat catagacgat
      901 gacgatgacg acatcaccct tacagttgag gcttcttgtc ataatggaga tgaaacaatt
      961 gagaccattg aggctgccga ggcactcctc aatatagatt ctcccagccc tcctgtactg
     1021 gatgaaaagc aaatcaataa taatatattt agctcctctg aagatgacat cgttgcccca
     1081 atcacccatg tgtccgtcac attagatggg attcctgaag tgatggaaac tcagcaagtg
     1141 caagagacaa atgcagactc cccaggagcc tcctccccag agcagcgcaa gagaaagaaa
     1201 ggaaggaaaa caaaaccacc acggccagat tccccgacga ctacaccaaa tatctctgtg
     1261 aaaaagaaaa ataaagatgg gaagggaaac acaatttacc tttgggagtt tttgctggcc
     1321 ctgcttcagg acaaagctac ctgtcctaag tacatcaagt ggacgcagcg agaaaagggc
     1381 atttttaagc tggttgattc taaagccgtg tctagattgt gggggaagca caaaaacaaa
     1441 cctgacatga actacgagac catggggaga gcactcaggt actattacca aagaggtatt
     1501 cttgcaaaag tggaaggtca gcgcttggtg tatcagttta aagaaatgcc aaaagatctt
     1561 atctacatag atgatgagga tccaagttcc agcatagagt cttcggatca gtccttatcg
     1621 tcaacaaccg catcaagtcg gaatcaagca aaccgatcaa gagtatcttc aagtccagga
     1681 attaaaggag gggccgctac aattctaaag cccgggaatt ctaaagctgc aaaccccaaa
     1741 gatccggtgg aagttggaca accttcagaa gttctgagga cagtgcaacc ctcacaggct
     1801 ccctatccta cccagctctt ccgaactgtt catgtagtac agccagtaca agctgtccca
     1861 gaggaagcaa ccatagccag caccatgcag gaggaagcag caaattcttc agttccaagt
     1921 attaggacta tacaggcttc aacccaggtt ccagtagtgg tgtctcctgg caaccaacag
     1981 ttacatacag taacagtgcc actcacaacg gttatagcca gcatagaccc atcatcaggt
     2041 gctgggtctc agaaattcat tttacaaacc attccatcgt cacagcccat gacagtactg
     2101 aaagaaaatg tcatgctaca gtcacagaag ccaggctctc cttcaattgt cctcagcccc
     2161 acccaagtac agcaggtcct cacaagcaat gttcagtcca tttgcaatgg agcgggcagt
     2221 gtggcatccg caccatcgtt cagcgcgacg acacctgtgg tgactttctc tcggagttca
     2281 cagctggtcg cacacccacc gggcactgtg atcacttctg ttatcaaagc tcaggaaaca
     2341 aaaactctta agcaagaggt ggagaaaaag gccgaagatg atttgaatga agatgctgag
     2401 aaaagtgccc agcagcccca gccttatgtg atggtgttat ccagttcaaa cgggttttcc
     2461 tctcaggtag ccgtcaaaca gaatgaactg ctagagccca actcttttta atacaccaaa
     2521 ggaattatgg gtgggtattt ttttaattga actcattttt cggttgtctg accataacat
     2581 gatttttttc taagatgaaa tccacagaag ttcttaactg ttaaaaagtt acttttgact
     2641 ttgctagata aggaggcgaa cccaagtgtg tgtctcctct gaatgtctca gaactcagtt
     2701 gtgaaggagc aggaggttta gacgatgaag aaattcttga ctgtttttca gttgctatat
     2761 catattttaa aagtttcttt tctagcttga cactgtacta gcttcctgaa ttgtttgaaa
     2821 atactactta aatataagac aacaggaaat ttatatagga aacattttca ttccacttgt
     2881 ataatttaag tcttagctct ttcagatgca agaaacttat actattaaaa ttgttgcgat
     2941 gtcacttagc ttgactttaa agttggctgg actgttatac tatgaatata ctacgaattt
     3001 gtaaactatc attataaatt gaagtgtata tgctcagtat attggcatat atgtgtaatt
     3061 ccagcactgg gaggaggaca aagggcaatc aggagttcaa ggccagcctt agctatatag
     3121 tgagtttgaa gccagcctgg gctacatgta accttcccaa aaaaatccaa aacaacaaca
     3181 aaaatattta agtgtgccta tgataatgtc tgaacctgag tttaagaaat gtgatgtagc
     3241 cgggcgtggt ggcacacgcc tttaatccca gcacttggga ggcagacgca ggtgaatttc
     3301 tgagtttgag gccagcctgg tctacagagt gagttccagg acagccaggg ctatacagaa
     3361 accctgtctc aaaacaaaca aacaaataaa aaaagaaatg tgatattata aaggcaacac
     3421 ttgtgacact tccactagct aggtgtgtaa ccctgggtag gccactccat ctcctaggtg
     3481 tgtaaccctg gacaggacat ttcacctgct agtctgtgct attctggtaa aatgaaggga
     3541 tgcattggac tagacaaaat gatctaaaag tttccttatt ataaatttta ggattttatt
     3601 atctgtactt taaaattatt tcaaatatta ccagattatc tccttatgta aaggtaaaat
     3661 actgcttaaa aatattttcc tcacaaaatt actatcaggt ctgccataaa ttcttcctaa
     3721 gttctctgct cattaatctt cagaccacag ttactaaaac tgtggcttag tagtaagctg
     3781 agggctaaat gagagactgc tattctaaga gcatcagggc tctgagggcc aaagaagcaa
     3841 tgggagtcct gagctagtat agctgtgtca cttattataa aagcataact gttttttatt
     3901 tggatcattt tttactgtgg gtgaagggga ggggaagttg catacaaaga tatatatcca
     3961 agtttccgaa gtagagtttt tagattactt tttcaatgta aataatgtat atttaatgtc
     4021 acaagaaatt gttttctgca aattctctag tatagaaagt tttgtagaag aaaaattatt
     4081 gtgtttaggg gtataatatt atatgttttc atattatgaa atgaatttgt atttaaacaa
     4141 aaatttaaat tttggaatcc tctaaacatt tttgtatctt taattgttat tattaaatca
     4201 tgtaaaagtt ctcaatattt ctgttttcaa gc
//
