LOCUS       NM_172706               8648 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus endosome-lysosome associated apoptosis and autophagy
            regulator family member 2 (Elapor2), transcript variant 1, mRNA.
ACCESSION   NM_172706
VERSION     NM_172706.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8648)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8648)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8648)
  AUTHORS   Araki,T., Kusakabe,M. and Nishida,E.
  TITLE     A transmembrane protein EIG121L is required for epidermal
            differentiation during early embryonic development
  JOURNAL   J Biol Chem 286 (8), 6760-6768 (2011)
   PUBMED   21177533
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158121.12, AC157783.7 and AC157555.9.
            
            On Jan 18, 2018 this sequence version replaced NM_172706.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133610.1, AK034358.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849387, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-339               AC158121.12        176195-176533
            340-460             AC157783.7         136021-136141
            461-656             AC157783.7         154924-155119
            657-804             AC157783.7         166327-166474
            805-891             AC157783.7         173728-173814
            892-997             AC157783.7         176360-176465
            998-1150            AC157783.7         177248-177400
            1151-1239           AC157783.7         178045-178133
            1240-1420           AC157783.7         183433-183613
            1421-1549           AC157783.7         184148-184276
            1550-1640           AC157783.7         190364-190454
            1641-1743           AC157783.7         191070-191172
            1744-1881           AC157783.7         193449-193586
            1882-2145           AC157783.7         196463-196726
            2146-2319           AC157783.7         197377-197550
            2320-2509           AC157783.7         201107-201296
            2510-2606           AC157783.7         202637-202733
            2607-2708           AC157783.7         203463-203564
            2709-2835           AC157555.9         125445-125571       c
            2836-3014           AC157555.9         123251-123429       c
            3015-3180           AC157555.9         121717-121882       c
            3181-8648           AC157555.9         100088-105555       c
FEATURES             Location/Qualifiers
     source          1..8648
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 3.69 cM"
     gene            1..8648
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /note="endosome-lysosome associated apoptosis and
                     autophagy regulator family member 2"
                     /db_xref="GeneID:231014"
                     /db_xref="MGI:MGI:2443264"
     exon            1..339
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     CDS             154..3240
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; estrogen-induced gene 121-like protein; UPF0577
                     protein KIAA1324-like homolog"
                     /codon_start=1
                     /product="endosome/lysosome-associated apoptosis and
                     autophagy regulator family member 2 isoform 1 precursor"
                     /protein_id="NP_766294.2"
                     /db_xref="CCDS:CCDS19089.1"
                     /db_xref="GeneID:231014"
                     /db_xref="MGI:MGI:2443264"
                     /translation="MLLLTLRRAKGRDRGRPAGGPRRALSLPWSPAWICCWALAGCQA
                     VWAGDSSSSGRPLPACQEKDYHFEYTECDSTGSRWRVAIPNSAVDCSGLPDPVKGKEC
                     TFSCASGEYLEMKNQVCSKCVEGTYSLGSGIKFDEWDELPAGFSNVATFMDTVVGPSD
                     SRPDGCNNSSWLPRGNYIESNRDDCTVSLIYAVHLKKSGYVFFEYQYVDNNIFFEFFI
                     QNDQCQEMDATTDKWVKLTDNGEWGSHSVMLKSGTNILYWRTTGILMGSKAVKPVLVK
                     NITIEGVAYTSECFPCKPGTFSNKPGSFNCQMCPRNTYSEKGAKECIRCKEDSQFSEE
                     GASECVDRPPCTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGEKK
                     DCPPCNPGFYNNGSSSCHPCPPGTFSDGTKECKSCPAGTEPALGFEYKWWNVLPANMK
                     TSCFNVGNSKCDGMNGWEVAGDHIRSGAGGSDNDYLILNLHIPGFKPPTSMTGATGSE
                     LGRITFVFETLCSADCVLYFMVDINRKSTNVVESWGGTKEKQAYTHVIFKNATFTFTW
                     AFQRTNQGQDNRRFINDVVKIYSITATNAVDGVAASCRACALGSEQSASSCVPCPPGH
                     YIEKETNQCKECPADTYLSIHQVYGKEACIPCGPGSKSTQDHSLCYSDCFFYHEKENQ
                     TLHYDFRNLSSVGSLMNGPSFTSKGTKYFHFFNISLCGHEGRKMALCTNNISDFTVKE
                     MVTGSDDYTNLVGAFVCQSTIIPSESKGFRAALSSQSIILADMFLGVTVDTALQNVNI
                     KEDMFPVSPSQVPDVHFFYKSSTATTSCINGRSTAVKMRCNPMRPGAGVISVPSKCPA
                     GTCDGCTFYFLWESAEACPLCTEHDFHEIEGACKRGLQEILYVWNEPKWCIKGISLPE
                     KKLSTCETVDFWLKVGAGVGAFTAVLLVALTCYFWKKNQKLEYKYSKLVMTTNSKECE
                     LPAADSCAIMEGEDNEEDVVYSNKQSLLGKLKSLATKEKDDHFESVQLKSSRCPNI"
     exon            340..460
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            461..656
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            657..804
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            805..891
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            892..997
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1150
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1239
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1420
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1549
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1640
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            1641..1743
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            1744..1881
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            1882..2145
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            2146..2319
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            2320..2509
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            2510..2606
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            2607..2708
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            2709..2835
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            2836..3014
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            3015..3180
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     exon            3181..8648
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4677..4682
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /note="hexamer: AATAAT"
     polyA_site      4706
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /note="major polyA site"
     regulatory      5793..5798
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /note="hexamer: ATTAAA"
     polyA_site      5812
                     /gene="Elapor2"
                     /gene_synonym="9330182L06Rik; Eig121l"
                     /note="major polyA site"
ORIGIN      
        1 ctctggcgtg acgggagctc gggcgccggc tgcccgcgct gcgagcggcc gagctgtaag
       61 cgtgcagatc agcccagttg agctgagccc agaggaggca agagcacggt cctcgcttcc
      121 cagactcctc gccggagtcc attcagtgcc gggatgctgc tgctcaccct gcggcgggcg
      181 aaaggcaggg atcgggggcg accggccggg ggtccccgcc gcgcgctctc gctgccctgg
      241 agccccgcct ggatttgctg ctgggcgctc gcaggctgcc aggcagtttg ggctggagac
      301 tcgtcctcct ctggccgccc gcttcctgcg tgccaagaga aagattacca ctttgaatat
      361 acagaatgtg atagcactgg ctccaggtgg agggtcgcca ttccgaattc tgcagtggat
      421 tgctctggcc tgcctgaccc agtgaaaggc aaagaatgca ctttctcctg tgcttctgga
      481 gagtatctag aaatgaagaa ccaggtatgc agtaaatgtg tggaaggcac ctactccttg
      541 ggcagtggca tcaaatttga tgaatgggat gaattgccgg caggattttc caacgttgca
      601 acattcatgg acactgtggt gggcccttct gacagcaggc cagatggctg taacaactct
      661 tcttggcttc ctcgtgggaa ctatatagag tctaaccgtg atgactgcac tgtgtctttg
      721 atctacgctg tgcacctgaa gaagtctggc tacgtcttct ttgagtacca gtacgtggac
      781 aacaacatct tctttgagtt ctttattcag aatgaccagt gccaggagat ggatgccacc
      841 acagacaagt gggtgaagct cacagacaat ggagaatggg gctcccattc tgtaatgctg
      901 aaatcaggca caaatattct gtactggaga acgacaggca tccttatggg ttctaaggca
      961 gtcaagcccg tgctagtaaa gaatatcacc atcgaagggg tggcatacac ctcagagtgc
     1021 tttccatgta agccaggcac tttcagcaac aaaccaggct catttaactg ccagatgtgt
     1081 cccagaaaca cctattctga gaagggtgct aaagaatgta ttaggtgtaa ggaggactcc
     1141 cagttttcag aggaaggagc cagtgagtgt gtggatcgcc caccctgcac taccaaagac
     1201 tatttccaga tccatacccc ctgtgacgaa gaagggaaga cacagataat gtacaagtgg
     1261 atagagccaa aaatctgcag ggaggatctc acagatgcta ttaggctgcc cccttctgga
     1321 gagaagaagg attgtcctcc ttgcaaccca ggattctata acaatggatc gtcttcttgc
     1381 catccctgcc ctccggggac gttttcagat ggaacaaagg aatgcaagtc atgtccggcc
     1441 ggaacagagc cagcacttgg gtttgaatat aaatggtgga atgtcctccc tgccaacatg
     1501 aaaacttcct gcttcaatgt tgggaattcc aagtgcgatg gaatgaacgg ttgggaggtg
     1561 gctggagatc acatccggag tggagctgga ggctctgaca atgactatct catcttaaac
     1621 ttgcacatcc caggatttaa accaccaacg tctatgactg gagccacagg ttcggaactg
     1681 ggaaggataa catttgtgtt tgagactctc tgctcagctg actgtgtttt gtacttcatg
     1741 gtggatataa atagaaaaag caccaatgtg gtggaatcat ggggaggaac caaagaaaag
     1801 caagcttata cgcatgtcat attcaagaat gcaacgttta catttacatg ggcgttccag
     1861 aggacaaacc aaggtcaaga taacagacga ttcatcaatg atgtggtgaa gatttattct
     1921 atcacagcca ctaatgcagt tgatggggta gcagcgtcat gtcgtgcctg tgccctgggc
     1981 tctgagcagt cggcctcatc atgtgtaccc tgccccccag gccactacat tgagaaggaa
     2041 accaaccagt gcaaggagtg tccagctgac acctacctgt ccatccacca ggtctatggc
     2101 aaggaagctt gcattccgtg tgggcctgga agtaaaagca cccaggacca ctcgctttgc
     2161 tatagcgact gctttttcta ccatgaaaaa gaaaaccaga ctctgcacta tgacttccgc
     2221 aacctcagca gtgtaggctc gctgatgaat ggccccagct tcacctccaa gggaacgaaa
     2281 tacttccatt tcttcaatat cagtttatgt ggacatgagg ggagaaagat ggctctctgt
     2341 accaacaata tttcagactt tacggtaaag gaaatggtga cagggtcaga tgattacaca
     2401 aatttggttg gagcatttgt atgccagtca actattattc cttctgaaag taagggcttc
     2461 cgggcagccc tgtcgtcaca gtctatcatt ctggcagata tgtttttagg tgtcactgtt
     2521 gacactgcct tgcaaaacgt taatatcaag gaggatatgt tcccagtgtc accgagccaa
     2581 gtaccagatg ttcatttctt ttataagtct tccacagcca ccacatcttg tattaatgga
     2641 cgatcgactg ctgtgaagat gaggtgtaat cccatgagac ctggtgcagg tgtgatatca
     2701 gtccccagca agtgtccagc tggcacctgt gatggttgta ccttctactt tctatgggag
     2761 agtgcagaag cttgccctct gtgcacagaa catgacttcc atgagatcga gggagcctgc
     2821 aagagagggc ttcaggaaat attatatgta tggaatgaac ctaagtggtg cattaaagga
     2881 atttctttgc ccgaaaagaa gttgtcaacc tgcgaaactg ttgacttttg gctgaaagtg
     2941 ggagctggtg tgggcgcgtt cacagccgtt ttgttggtgg ctttaacatg ctacttttgg
     3001 aaaaagaatc aaaagctgga atacaaatat tctaaattag taatgacgac taactcaaaa
     3061 gagtgtgaac tcccagctgc agacagctgt gctatcatgg aaggagaaga taatgaagag
     3121 gatgttgtat attccaacaa acagtcacta ctaggaaaac ttaagtcttt ggccacaaag
     3181 gaaaaagatg accactttga gtctgttcag ctgaaatcct caagatgccc caatatatga
     3241 agagacaatg ctgtagcatt caggaccccc attaggactt gtcctcacat ctgacatggc
     3301 tgtgatctca caaaggaggt gtgccaatga gaggaggagg caaaaatgct gattgcctta
     3361 taacatgtca catactttgt caaactacag aagacagatg atgtgggtct cactgaagat
     3421 gaagcttaac tcaggaagag atttagctgt atatacacat aactgaaacc caagtttaag
     3481 cccaccaatg cactgctgag catgccatat gattactggg taactttaat tctttatact
     3541 gtctacatac aaaatatgtg ttggaaggca gacataaaca tatgccttgt gtttccacgt
     3601 atgtcttgtt cttgtacttt gggagaagat ttggaaaaaa aattaagtta taattatttt
     3661 tacttttctt tctccaagac ttgaaaacat cttttttttt taattaaaat gatgagtaat
     3721 gaaagacaaa ttttcatagg ttattttctc ttaacttcag aagcctagga tatcagtaat
     3781 attttgtgaa gttatttaat tttgttatct aagatgataa tcccttttaa aaattctttc
     3841 cttgtttgaa ctagtatgaa aaatttaatt gtttgaagga atctcatggg atgggattgg
     3901 aggtgataaa agccaagaag aagcctcaac attccattaa tttagacaat ctggcattat
     3961 cagaagtcaa aggcttaaag catttgagtg ttgttaaaga ataaaaggtg tgtgcggagc
     4021 accttgttta gtaaacccct gcatagtcat gaggaaggag agatacagct taaccctaag
     4081 cacagaaaac tctgcttgtt tgggctacaa gtgtcagctg ggccatccct cctcaccagg
     4141 caccaaccag agcactgcag gtttttatgt tttctttgct agaagacttt gaggattatg
     4201 aatttcttga agattttatt tttaagccaa taaggaagaa gttcaatttt tgaaatgcat
     4261 atacttgtat tcatagtaac caccttctta gcaatgcatt gttcttgttc gaaagcaacc
     4321 cagaaacttg tgacatttct catgatggat taccagtatt agtgtgactt ggatattatt
     4381 tttgaaagaa gtttgacggt gaacttgatc aagcttgtgt aaacatttag acctgggaat
     4441 tagagtatct tacccattat tgatataaga tgttctggtt tgtttccaat aaaccaataa
     4501 tctttataga tcttaatcca gatatttaaa aagatttttg attggctgaa ggaggcaaag
     4561 cttatgagta aggttttcac catgtgtttt tcctggtgtt tcagtgcttg taatatttga
     4621 ttttgtgggt gatgtagtct ttatttttgt gaaaaatggg agaaaatgaa taaatgaata
     4681 attgtgctta ttggccagag ggtaaaccac tagacctttt tgctaccact aaaagaatgg
     4741 ttgaatgcat gtgtatatgt gtgtgtgcat gtacatgtgt gtatgtgagt atgtatgtat
     4801 ctactactaa gtataaaaat aggtgatgta ttattgtttg tcataagact gaagagaatg
     4861 ttacttagca taatttttgc atttaatttc ttgaatattc taaattattt tggctttgct
     4921 cacttttgtc ccaatgtcag aatattggca tggctttccc tatcataatc aaaatttaac
     4981 caggagagtg gaaatacact tgaaatatca ctcagaggaa ctggtgcaaa gtacagactg
     5041 gacagagtca gaaagattct tctgtcacct gtcactcttc ttcaccctct cctgtgctca
     5101 acatgtatgt tccaagccat agaaataatt gggatttgct cccaggtact tctttctctt
     5161 gtcactggac tgaaatctgt gacatgtcaa aaatgcctta aactttaatg aactctctga
     5221 aaatgtagtt gatattgaag aacttatttt atttctaatt ttagatatta aatagatttt
     5281 cattttgtca gctcagtccc atctttggat tcccatggct tgtcatttta ttctaagaga
     5341 tgaagaacta tgacagaata ttatgaggag aatatgcaga ccaattttag ctataaaatt
     5401 gtttagtttt atgtatggcc tttgataagc ccagtgaaat gttaaaagct ataactaaat
     5461 tattctgcct ctatgaccta ttgacactta ctctccccat cacaaccagt gatagaaaaa
     5521 tacattattt attatttttt ctaaaaggca tactttggag ccttaaatac ttcattaagt
     5581 caactgttgt gtataacatc tcttagcact gtgtcaaaac atatttaagt catttttcta
     5641 ctggatgaga acatgtcttc tatggataaa ttatattatg ctatttaaca atgttgagca
     5701 atttggtata tattcacttg atttaaatga ctgaatttta ttattattgg cccttttcct
     5761 ttttggttac taataatcat atccttctta ggattaaaca tatttcatag tactttttgt
     5821 atagactttt gtcattattt ttctccccta aaatgataaa atggtttaag ttagtacagt
     5881 ggaagaatta cttgagagca gttattcacc atttgggttc tcaggtgttg ggtaacagtg
     5941 ggtttgcttc tttaagtccc atctagccaa gtgtcattgg atgtcttttg gtaacagtgt
     6001 ttcccatggc tcatggtcat ttttagtggg aggctgatat gtttctattt tcctcataaa
     6061 acccagttgc ttggttagtg tgaaatgtgc tgctaatact tatattctca tactgatgcc
     6121 ttctgaggat cagacgctga catacaaaat agtgtagatt cctaagatgt ggtactagag
     6181 aggcttccat gtctatttac ttgtgatgta gggtgtacct cagtgctcac ccatttacca
     6241 ggtccagctt caatatgaaa ctgcaaatgt catttagttt tcctttaatg attgttggtt
     6301 cagcaaacac ctccaatttt gtcgaacaaa gtatcaatta agaccttggt tagctggatt
     6361 tttcttcatt gtaataactc ccgagagtta gtacaataat aatagagagg cttctattta
     6421 aaatacctta tgagttttgg ctaatgattg ggcaatattt tctccatgtc agataactga
     6481 ttttaaaatt ctattggctg ctttccaaat aaaaagagga aaccaataag aattatgtaa
     6541 atccaagcct gctgttgcag tgaaagatgg ttaatggctt cacccatggg tgtgtgcctt
     6601 tgtctcaagg tgctagttca gacctctctt tgtggctttt cacattttcc cacacagaca
     6661 ggctactgga ttgcaaatat tctcaatggg gaagcaggtg atgcaggtcc tagctgagag
     6721 aacatgtgca cccaaagcct gtaaagacag agattacctt tctcggtcat tctttacatc
     6781 tgtcttctgt gttgtccaga agccggcttg ccttgcagtt taaaaatagg aacagctttc
     6841 cttcaccatt ctaaacttgg gtgtgcggga aaatctatta atatttaagc tagagaagat
     6901 gcagagtata gtaactgttc agaaacacaa ggcaagcagc tagcttgctt ctaaaagttt
     6961 ctttaatgaa taggatctat tatttagctt gggaattctt aaatttaggg aagttttgct
     7021 gagatcaatc tatcggcttt acattctgga agggtaaaat gttgttacta atgtggggga
     7081 aaaggcttcc aaaactattt tttaatggct tgcataaaaa tgattttata atgcctgttt
     7141 tccatacata tgttgaatgt tcataaaaat tatttctagg gatcatatgg taggtggtga
     7201 aattctaatt aaaaacaaga ctttgtagca aggatgaaaa aaatgacaag agctgcctgt
     7261 tactatattt ttagtgtact gacagggcat aaaatacaga gagtataaaa gccccagcct
     7321 tccaaactac agttgtctca tgatttagac acaacctgat tgtcgtgctt taagatccat
     7381 gatcagcttg actgtgagag gcatcagctg tacctctgaa cagcccatct gatattgcca
     7441 tcctcagact gtcacattcc atcaggggac tgagtttatt ttctctctca tcagcttgca
     7501 gagccactgt cccaagcaga cgctcattcc gattctgctt atcaattcac tgtgctattt
     7561 agtgtctttg aatctgttac tcaacctacc ctagctcact ccctgaattt caggcactta
     7621 cttgagtgtg agaattcaag gagcactcag caccactgtt ttctaattgg ctagagctag
     7681 attccttagg tcgctcattc aaatgcatgc ataagaagag caaatctagc tttctgtttc
     7741 cttccaggcc aatctccttg gccattatgc ccctgttcat tctttttaga ttactaaaaa
     7801 tataattact atggcttctt tacttcaaat actatctctc atgtatttaa ttctatactt
     7861 cactcctttc tcttttgttc ttgactgctt ttcagatatt ttcttgtgca tgcaaaacaa
     7921 acaccaattg atttatatcc gcatctctag tttgtgcttt tcaaatgcag gaactagatg
     7981 gacttgatct cattgtcttt ctgttgtggg ctacttagtg gcctctcaaa aatatgtcca
     8041 tatcctagtc cctgaaccct gagaacacta ttttatttta aaataaaaac aaaacaaaca
     8101 ccaaaacaaa agaaaacagc tacaacaaga aacttcaaac aaatggccta ttaagaatat
     8161 ggaggtgata agtatcctgg gttatctagg tcactctgca cctaacgaca catgaaattt
     8221 taggagacaa aagacaagac agacacagtg gtgaatatga tatggtgact gaacagagtt
     8281 tgaaatgatg tggccagagg ccagggaact ctaactacca ggtgctagga aaaggatgag
     8341 atgggcgatt tctttgaatc tataaggcag cctggtcctt ctgactcctt cactgtgaca
     8401 gaataacttt ttgttgtttt aagccacata cattataaca tttttcccca tcaacacagg
     8461 aaaaaatgta ctctctgccc tgtatgtgac ataggtttta cagatagatg tattctcaat
     8521 atttaacccg acattgataa attatttgtg actaaaagtt tgatagaagc agggaagtat
     8581 ttagtaagat tcttacccat actattcatg ccttattttg agttaataaa atatttaaag
     8641 ttaatgac
//
