LOCUS       NM_145941               5358 bp    mRNA    linear   ROD 08-AUG-2024
DEFINITION  Mus musculus eukaryotic translation initiation factor 4, gamma 1
            (Eif4g1), transcript variant 1, mRNA.
ACCESSION   NM_145941
VERSION     NM_145941.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5358)
  AUTHORS   Borisova,E., Newman,A.G., Couce Iglesias,M., Dannenberg,R.,
            Schaub,T., Qin,B., Rusanova,A., Brockmann,M., Koch,J., Daniels,M.,
            Turko,P., Jahn,O., Kaplan,D.R., Rosario,M., Iwawaki,T.,
            Spahn,C.M.T., Rosenmund,C., Meierhofer,D., Kraushar,M.L.,
            Tarabykin,V. and Ambrozkiewicz,M.C.
  TITLE     Protein translation rate determines neocortical neuron fate
  JOURNAL   Nat Commun 15 (1), 4879 (2024)
   PUBMED   38849354
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5358)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 5358)
  AUTHORS   Kim,S.H., Choi,J.H., Marsal-Garcia,L., Amiri,M., Yanagiya,A. and
            Sonenberg,N.
  TITLE     The mRNA translation initiation factor eIF4G1 controls
            mitochondrial oxidative phosphorylation, axonal morphogenesis, and
            memory
  JOURNAL   Proc Natl Acad Sci U S A 120 (25), e2300008120 (2023)
   PUBMED   37307456
  REMARK    GeneRIF: The mRNA translation initiation factor eIF4G1 controls
            mitochondrial oxidative phosphorylation, axonal morphogenesis, and
            memory.
REFERENCE   4  (bases 1 to 5358)
  AUTHORS   Liang,R., Shen,X., Wang,F., Wang,X., DesJarlais,A., Syed,A.,
            Saba,R., Tan,Z., Yu,F., Ji,X., Shrestha,S., Ren,Y., Yang,J.,
            Park,Y., Schwartz,R.J., Soibam,B., McConnell,B.K., Stewart,M.D.,
            Kumar,A. and Liu,Y.
  TITLE     H19X-encoded miR-322(424)/miR-503 regulates muscle mass by
            targeting translation initiation factors
  JOURNAL   J Cachexia Sarcopenia Muscle 12 (6), 2174-2186 (2021)
   PUBMED   34704401
REFERENCE   5  (bases 1 to 5358)
  AUTHORS   Morandell,J., Schwarz,L.A., Basilico,B., Tasciyan,S., Dimchev,G.,
            Nicolas,A., Sommer,C., Kreuzinger,C., Dotter,C.P., Knaus,L.S.,
            Dobler,Z., Cacci,E., Schur,F.K.M., Danzl,J.G. and Novarino,G.
  TITLE     Cul3 regulates cytoskeleton protein homeostasis and cell migration
            during a critical window of brain development
  JOURNAL   Nat Commun 12 (1), 3058 (2021)
   PUBMED   34031387
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5358)
  AUTHORS   Strong,R. and Belsham,G.J.
  TITLE     Sequential modification of translation initiation factor eIF4GI by
            two different foot-and-mouth disease virus proteases within
            infected baby hamster kidney cells: identification of the 3Cpro
            cleavage site
  JOURNAL   J Gen Virol 85 (Pt 10), 2953-2962 (2004)
   PUBMED   15448358
  REMARK    Erratum:[J Gen Virol. 2004 Dec;85(Pt 12):3817]
REFERENCE   7  (bases 1 to 5358)
  AUTHORS   Orton,K.C., Ling,J., Waskiewicz,A.J., Cooper,J.A., Merrick,W.C.,
            Korneeva,N.L., Rhoads,R.E., Sonenberg,N. and Traugh,J.A.
  TITLE     Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK
            inhibits phosphorylation and interaction of eIF4G with Mnk
  JOURNAL   J Biol Chem 279 (37), 38649-38657 (2004)
   PUBMED   15234964
  REMARK    GeneRIF: eIF4G binding to Mnk is inhibted by Mnk1 phosphorylation
            by caspase-activated Pak2/gamma-PAK
REFERENCE   8  (bases 1 to 5358)
  AUTHORS   Joshi,B., Cameron,A. and Jagus,R.
  TITLE     Characterization of mammalian eIF4E-family members
  JOURNAL   Eur J Biochem 271 (11), 2189-2203 (2004)
   PUBMED   15153109
REFERENCE   9  (bases 1 to 5358)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   10 (bases 1 to 5358)
  AUTHORS   Kimball,S.R., Horetsky,R.L., Ron,D., Jefferson,L.S. and
            Harding,H.P.
  TITLE     Mammalian stress granules represent sites of accumulation of
            stalled translation initiation complexes
  JOURNAL   Am J Physiol Cell Physiol 284 (2), C273-C284 (2003)
   PUBMED   12388085
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC087898.19.
            
            On Mar 30, 2022 this sequence version replaced NM_145941.3.
            
            Summary: This gene encodes a member of the eukaryotic translation
            initiation factors (eIF) that play important roles in translation
            initiation by mediating recruitment of additional initiation
            factors and providing a scaffold for ribosome/mRNA-bridging. Along
            with eIF4A and eIF4E, the encoded protein forms the eIF4F complex
            that bridges the 5' UTR with the polyadenylated 3' UTR resulting in
            mRNA circularization, enhanced translation initiation and mRNA
            stability. Through its association with eIF3, the encoded protein
            mediates recruitment of the 43S pre-initiation complex to mRNA.
            Alternative splicing of this gene results in multiple transcript
            variants. Pseudogenes for this gene have been identified on
            chromosomes 2 and 13. [provided by RefSeq, Jan 2015].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079675.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849379, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-69                AC087898.19        32238-32306         c
            70-163              AC087898.19        31153-31246         c
            164-250             AC087898.19        30800-30886         c
            251-271             AC087898.19        30308-30328         c
            272-448             AC087898.19        29594-29770         c
            449-548             AC087898.19        29285-29384         c
            549-661             AC087898.19        27316-27428         c
            662-754             AC087898.19        26440-26532         c
            755-821             AC087898.19        26164-26230         c
            822-1634            AC087898.19        25089-25901         c
            1635-1723           AC087898.19        24313-24401         c
            1724-1910           AC087898.19        24038-24224         c
            1911-2044           AC087898.19        23798-23931         c
            2045-2203           AC087898.19        23536-23694         c
            2204-2389           AC087898.19        23192-23377         c
            2390-2587           AC087898.19        22875-23072         c
            2588-2734           AC087898.19        22309-22455         c
            2735-2971           AC087898.19        21460-21696         c
            2972-3076           AC087898.19        21198-21302         c
            3077-3236           AC087898.19        20933-21092         c
            3237-3337           AC087898.19        20606-20706         c
            3338-3440           AC087898.19        19501-19603         c
            3441-3537           AC087898.19        19159-19255         c
            3538-3764           AC087898.19        18737-18963         c
            3765-3883           AC087898.19        18483-18601         c
            3884-4056           AC087898.19        18182-18354         c
            4057-4182           AC087898.19        17839-17964         c
            4183-4264           AC087898.19        17652-17733         c
            4265-4363           AC087898.19        16477-16575         c
            4364-4498           AC087898.19        16249-16383         c
            4499-4580           AC087898.19        16062-16143         c
            4581-4721           AC087898.19        15782-15922         c
            4722-5358           AC087898.19        12231-12867         c
FEATURES             Location/Qualifiers
     source          1..5358
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 12.49 cM"
     gene            1..5358
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /note="eukaryotic translation initiation factor 4, gamma
                     1"
                     /db_xref="GeneID:208643"
                     /db_xref="MGI:MGI:2384784"
     exon            1..69
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            70..163
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..4906
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /note="isoform a is encoded by transcript variant 1"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 4 gamma
                     1 isoform a"
                     /protein_id="NP_666053.2"
                     /db_xref="CCDS:CCDS28055.1"
                     /db_xref="GeneID:208643"
                     /db_xref="MGI:MGI:2384784"
                     /translation="MNKAPQPTGPPPARSPGLPQPAFPPGQTAPVVFSTPQATQMNTP
                     SQPRQGGFRSLQHFYPSRAQPPSSAASRVQSAAPARPGPAPHVYPAGSQVMMIPSQIS
                     YSASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQ
                     FPASVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQT
                     GGSLEPQPNGESPQVAVIIRPDDRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSP
                     PPILEPGSESNLGVLSIPGDTMTTGMIPMSVEESTPISCETGEPYCLSPEPTLAEPIL
                     EVEVTLSKPIPESEFSSSPLQVSTALVPHKVETHEPNGVIPSEDLEPEVESSTEPAPP
                     PLSPCASESLVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKKVSSAALASILSP
                     APPVAPSDTSPAQEEEMEEDDDDEEGGEAESEKGGEDVPLDSTPVPAQLSQNLEVAAA
                     TQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEVDPAVPEVENQPPTGSNPSPESEGSM
                     VPTQPEETEETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGF
                     QFIFASMQKPEGLPHITDVVLDKANKTPLRQLDPSRLPGINCGPDFTPSFANLGRPAL
                     SNRGPPRGGPGGELPRGPAGLGPRRSQQGPRKETRKIISSVIMTEDIKLNKAEKAWKP
                     SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERL
                     KGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFE
                     KDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKM
                     LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKIIKE
                     KKTSSRIRFMLQDVLDLRQSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAK
                     GSDKRRGGPPGPPINRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQL
                     FAPGGRLSWGKGSSGGSGAKPSDTASEATRPATLNRFSALQQTLPAENTDNRRVVQRS
                     SLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPE
                     GLRKAASLTEDRGRDPVKREATLPPVSPPKAALSVDEVEKKSKAIIEEYLHLNDMKEA
                     VQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLY
                     ETLELAEDMEIDIPHVWLYLAELITPILQEDGVPMGELFREITKPLRPMGKATSLLLE
                     ILGLLCKSMGPKKVGMLWREAGLSWREFLAEGQDVGSFVAEKKVEYTLGEESEAPGQR
                     TLAFEELRRQLEKLLKDGGSNQRVFDWIDANLNEQQIASNTLVRALMTTVCYSAIIFE
                     TPLRVDVQVLKVRARLLQKYLCDEQKELQALYALQALVVTLEQPANLLRMFFDALYDE
                     DVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFNWLREAEDEESDHN"
     exon            164..250
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            251..271
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            272..448
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            449..548
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            549..661
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            662..754
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            755..821
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            822..1634
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1723
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            1724..1910
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            1911..2044
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            2045..2203
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            2204..2389
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            2390..2587
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            2588..2734
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            2735..2971
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            2972..3076
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            3077..3236
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            3237..3337
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            3338..3440
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            3441..3537
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            3538..3764
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            3765..3883
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            3884..4056
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            4057..4182
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            4183..4264
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            4265..4363
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            4364..4498
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            4499..4580
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            4581..4721
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     exon            4722..5358
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5338..5343
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /note="hexamer: ATTAAA"
     polyA_site      5358
                     /gene="Eif4g1"
                     /gene_synonym="E030015G23Rik; eIF-4-gamma 1; eIF-4G 1;
                     eIF-4G1; eIF4GI"
                     /note="major polyA site"
ORIGIN      
        1 ggaaatggtt gtggactacg tctgtgcggc tgcgtggggc tcggccgcgc ggactgaagg
       61 agactgaagg tgctgggggg accctaatgt ggcaccaaat gaaatgaaca aagctcccca
      121 gcccacaggc cccccacccg ccaggtcccc tggactccca cagccagcgt ttcccccggg
      181 gcagactgca ccggtggtgt ttagcacgcc tcaagcgaca caaatgaaca cgccttctca
      241 gccccgccag ggaggattca ggtctctgca gcacttctac cctagccggg cccagccccc
      301 tagcagtgca gcctcccgag tgcagagtgc agcccctgcc cgtcctggcc cagctcccca
      361 tgtctaccct gctggatccc aagtaatgat gatcccttcc cagatctcct actcagcctc
      421 ccaaggagcc tactatatcc ctggacaggg gcgttccaca tatgttgtcc caacacagca
      481 gtaccctgtg cagccaggag ccccaggctt ctatccaggt gcaagcccta ccgagtttgg
      541 gacctatgct ggagcctatt acccagccca aggtgtgcag cagtttcctg ctagtgtggc
      601 tcctgcccca gttttgatga accagccacc ccagattgct cctaagaggg aacggaaaac
      661 tatccgaatt cgagacccaa accaaggagg gaaggatatc acagaagaga tcatgtctgg
      721 ggcccgcact gcctccacac ccactcctcc ccagacggga ggcagtctgg agcctcaacc
      781 caatggggag tcgcctcagg ttgctgtcat tatccggcca gatgaccggt cgcagggagc
      841 agccattggg gggcggccag gactgcctgg cccagagcat agccctggca cagaatctca
      901 gccttcgtcg ccttctccaa ccccatcacc acccccaatt ttggagccgg ggtctgagtc
      961 taatcttgga gtcctctcta ttcctgggga cactatgaca acagggatga taccaatgtc
     1021 tgtagaagaa tcgaccccta tctcttgtga aactggggag ccgtattgcc tctctccaga
     1081 acccactctt gccgaaccca tactggaagt agaagtgaca ctcagcaaac ccattccaga
     1141 atctgagttc tcttccagtc ctctccaggt ttccacggcc ctggtgcctc acaaggttga
     1201 aactcatgag cccaatggcg tgatcccatc tgaggatctg gaaccagagg tggagtcaag
     1261 cacagagcca gctcctcccc ctctatcacc ttgtgcttct gaatcgctcg tgcccattgc
     1321 tccaactgcc cagcctgagg aactgctcaa cggagccccc tcaccaccag ctgtggattt
     1381 aagcccagtc agtgagccag aggaacaggc caagaaggtt tcatcagcag cactggccag
     1441 cattctctct cctgctccac ctgtggctcc ttcagatact tctcctgctc aggaggaaga
     1501 aatggaagaa gatgacgatg acgaagaagg tggagaagct gagagtgaga agggaggaga
     1561 ggacgtcccc cttgacagta ctcctgtccc agcccagctg tctcagaatt tagaggtggc
     1621 agcagctacc caggtggcag tgtctgtgcc aaagaggaga cggaaaatta aagagctaaa
     1681 taagaaggag gctgtaggag accttctaga tgccttcaag gaggtggacc cagcagtacc
     1741 agaggtagag aatcagcctc ccactggcag caacccaagc ccagagtctg agggcagcat
     1801 ggtgcccaca cagcctgagg aaacagaaga aacctgggac tctaaggaag acaaaattca
     1861 taatgctgag aacatccagc ctggggagca gaagtatgag tacaagtcag atcagtggaa
     1921 gcctctaaac cttgaagaaa agaagcgtta tgacagagaa ttcctgctgg gctttcagtt
     1981 catctttgcc agcatgcaga agccagaagg attgccccat atcactgatg tggtgctgga
     2041 caaggccaat aaaacaccac ttcggcaact ggatccctcc agactacctg gcataaactg
     2101 tggcccagat ttcactccat cttttgccaa tcttggccga ccagccctca gcaaccgtgg
     2161 gcccccgagg ggtgggccag gtggggagct gccccgaggg ccggctggcc tgggacccag
     2221 gcgctctcag cagggcccac gaaaggaaac tcgcaagatc atttcctcag tgataatgac
     2281 tgaagacata aaactaaata aagcagagaa ggcttggaaa cccagtagca aacggacagc
     2341 agctgataag gatcgagggg aagaggatgc tgatggaagc aagacccagg acctgttccg
     2401 cagggtacgc tccatcctga ataagctgac accccagatg tttcagcagc tgatgaagca
     2461 ggtgacacag ctggccattg acacggagga acgcctcaaa ggagttattg acctcatctt
     2521 tgagaaagcc atttcagagc ccaacttctc tgtggcttat gccaacatgt gccgctgcct
     2581 catggcgctg aaagtgccca ctacagaaaa gccaacagta actgtgaatt ttcgaaaact
     2641 gttgttaaat cggtgccaga aggaatttga gaaagacaaa gatgatgatg aagtttttga
     2701 aaaaaagcaa aaagagatgg atgaagctgc tacggcagaa gaacggggac gcctgaaaga
     2761 agagctagaa gaagcccggg acatagctag gcggcgctct ttagggaata tcaagtttat
     2821 tggagagtta ttcaagttga agatgttaac agaagcaata atgcatgact gtgtggtcaa
     2881 gctacttaag aaccatgatg aggagtccct ggaatgcctc tgccgcctcc tcaccactat
     2941 aggcaaagac ctggactttg caaaagccaa gcctcgaatg gatcagtatt tcaaccaaat
     3001 ggaaaaaatc attaaagaaa agaagacctc atctcgcatc cgttttatgc tgcaggatgt
     3061 actcgatctg cggcagagta attgggtgcc acgccgaggg gatcagggtc ctaagactat
     3121 tgatcaaatt cacaaggagg ctgagatgga agagcaccga gaacatatta aagtacagca
     3181 gctcatggcc aagggcagcg acaaacgtcg gggtggccct ccaggcccgc ctatcaaccg
     3241 tggccttcca cttgtagatg atggtggctg gaatacagtc cccattagca aaggcagtcg
     3301 ccccattgac acctcacggc tcaccaagat cacaaagcct ggttccattg attctaacaa
     3361 ccagcttttt gcacctggag gacgactgag ttggggcaag ggcagcagtg ggggctcagg
     3421 agccaagccc tcagacacag catcggaagc tactcgtcca gctaccttga atcgcttttc
     3481 tgctcttcaa caaacattac ccgcagagaa cacagataac agacgtgttg tacagaggag
     3541 tagcttgagc cgggaacgag gtgagaaagc tggggaccgg ggagaccgac tagagcggag
     3601 tgagcgggga ggtgaccgtg gggaccgact tgatcgtgcc agaacacctg ccaccaagcg
     3661 aagttttagc aaagaagtgg aggagcgaag tagagagcgg ccatcccagc ctgagggact
     3721 ccgcaaggca gctagcctca cagaggatcg tggtcgggat cctgtgaagc gggaagccac
     3781 tctacctcca gtgagccctc caaaggctgc gctgtctgtg gatgaggtgg agaagaaatc
     3841 taaggccatc attgaggaat atctccatct caatgacatg aaggaggcag tacagtgtgt
     3901 ccaggagctg gcttcaccct ccttgctctt catcttcgta cggcttggta tcgagtccac
     3961 gctggagcgt agtaccattg ctcgtgagca tatggggcga ctactgcacc aactgctctg
     4021 tgcggggcac ctctctactg cccagtacta tcaagggctg tatgaaacac tagaattggc
     4081 tgaggacatg gaaattgata tccctcatgt atggctttac ctggcagaac tgattacacc
     4141 tattctccag gaagatgggg tgcccatggg agagctcttc agggaaatta cgaagcctct
     4201 gagacccatg ggcaaagcta cttctttatt gctggagatc ctgggtctct tatgcaagag
     4261 catgggtccc aaaaaggtgg ggatgctgtg gcgagaggct gggctgagct ggagggaatt
     4321 tctagcagag ggccaagacg ttggctcatt tgtggctgaa aagaaggtgg aatatacctt
     4381 gggagaagaa tctgaagctc ctggccagag gacacttgcc tttgaggagc ttcgtaggca
     4441 gctagagaag ctgctgaagg acggcggcag taatcagcgt gtgttcgact ggatagacgc
     4501 caacctaaat gagcagcaga tagcatccaa tacattagtt cgagccctca tgacaactgt
     4561 ctgttattct gcaattatct ttgagactcc tctccgagtg gatgttcaag tgttgaaagt
     4621 gcgagcaaga ctgctgcaga aatacctgtg tgatgagcag aaggagctac aagcactcta
     4681 tgctctccag gcccttgtag tgaccttaga acagcctgcc aacctgcttc ggatgttctt
     4741 tgatgctcta tatgatgagg acgtggtgaa ggaagacgcc ttctacagct gggagagcag
     4801 caaggatcct gctgaacagc agggcaaggg tgtggccctt aaatctgtca cagcattctt
     4861 caattggctt cgtgaggctg aggacgagga gtctgatcac aactgatggc gggtggggca
     4921 ggggacttgg agccatggac acgtggatgg cccagccagc cagccgcctg gactgcaggg
     4981 gggcggcagc agcagtggcg gcagtggcag tgggtgcctg tagtgcgatg tgtcttgagc
     5041 taataaagtg gctgatgagg caggatggct tggggctgcc tgggcccccc ccccctccag
     5101 gatgctgcca agtgtctctc tcctcccccc agggcacaga gatatatata aagtcttgaa
     5161 atttggtgtg tctttgcggg gggaagggca ctaccgcctg cctctagggt ccttttttat
     5221 tttctgaaat cactcttggg actgccgtcc tcgctgctgg gggcatatgc cccagcccct
     5281 gcaccacccc tgctgctgcc tgggcagggg aaaggggggg gcacggtgcc tgtaattatt
     5341 aaacatgaat tcaattaa
//
