LOCUS       NM_025344               1507 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus eukaryotic translation initiation factor 3, subunit F
            (Eif3f), mRNA.
ACCESSION   NM_025344
VERSION     NM_025344.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1507)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1507)
  AUTHORS   Fujii,K., Zhulyn,O., Byeon,G.W., Genuth,N.R., Kerr,C.H., Walsh,E.M.
            and Barna,M.
  TITLE     Controlling tissue patterning by translational regulation of
            signaling transcripts through the core translation factor eIF3c
  JOURNAL   Dev Cell 56 (21), 2928-2937 (2021)
   PUBMED   34752747
REFERENCE   3  (bases 1 to 1507)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1507)
  AUTHORS   Docquier,A., Pavlin,L., Raibon,A., Bertrand-Gaday,C., Sar,C.,
            Leibovitch,S., Candau,R. and Bernardi,H.
  TITLE     eIF3f depletion impedes mouse embryonic development, reduces adult
            skeletal muscle mass and amplifies muscle loss during disuse
  JOURNAL   J Physiol 597 (12), 3107-3131 (2019)
   PUBMED   31026345
  REMARK    GeneRIF: eIF3f depletion impedes mouse embryonic development,
            reduces adult skeletal muscle mass and amplifies muscle loss during
            disuse.
REFERENCE   5  (bases 1 to 1507)
  AUTHORS   Varum,S., Baggiolini,A., Zurkirchen,L., Atak,Z.K., Cantu,C.,
            Marzorati,E., Bossart,R., Wouters,J., Hausel,J., Tuncer,E.,
            Zingg,D., Veen,D., John,N., Balz,M., Levesque,M.P., Basler,K.,
            Aerts,S., Zamboni,N., Dummer,R. and Sommer,L.
  TITLE     Yin Yang 1 Orchestrates a Metabolic Program Required for Both
            Neural Crest Development and Melanoma Formation
  JOURNAL   Cell Stem Cell 24 (4), 637-653 (2019)
   PUBMED   30951662
REFERENCE   6  (bases 1 to 1507)
  AUTHORS   Csibi,A., Leibovitch,M.P., Cornille,K., Tintignac,L.A. and
            Leibovitch,S.A.
  TITLE     MAFbx/Atrogin-1 controls the activity of the initiation factor
            eIF3-f in skeletal muscle atrophy by targeting multiple C-terminal
            lysines
  JOURNAL   J Biol Chem 284 (7), 4413-4421 (2009)
   PUBMED   19073596
  REMARK    GeneRIF: MAFbx/Atrogin-1 controls the activity of the initiation
            factor eIF3-f in skeletal muscle atrophy by targeting multiple
            C-terminal lysines.
REFERENCE   7  (bases 1 to 1507)
  AUTHORS   Lagirand-Cantaloube,J., Offner,N., Csibi,A., Leibovitch,M.P.,
            Batonnet-Pichon,S., Tintignac,L.A., Segura,C.T. and Leibovitch,S.A.
  TITLE     The initiation factor eIF3-f is a major target for atrogin1/MAFbx
            function in skeletal muscle atrophy
  JOURNAL   EMBO J 27 (8), 1266-1276 (2008)
   PUBMED   18354498
  REMARK    GeneRIF: Key target that accounts for E3 ubiquitin ligase MAFbx
            (atrogin1, Fbxo32) function during muscle atrophy; has a major role
            in skeletal muscle hypertrophy.
REFERENCE   8  (bases 1 to 1507)
  AUTHORS   Masutani,M., Sonenberg,N., Yokoyama,S. and Imataka,H.
  TITLE     Reconstitution reveals the functional core of mammalian eIF3
  JOURNAL   EMBO J 26 (14), 3373-3383 (2007)
   PUBMED   17581632
REFERENCE   9  (bases 1 to 1507)
  AUTHORS   Harris,T.E., Chi,A., Shabanowitz,J., Hunt,D.F., Rhoads,R.E. and
            Lawrence,J.C. Jr.
  TITLE     mTOR-dependent stimulation of the association of eIF4G and eIF3 by
            insulin
  JOURNAL   EMBO J 25 (8), 1659-1668 (2006)
   PUBMED   16541103
REFERENCE   10 (bases 1 to 1507)
  AUTHORS   Min,S.H., Simmen,R.C., Alhonen,L., Halmekyto,M., Porter,C.W.,
            Janne,J. and Simmen,F.A.
  TITLE     Altered levels of growth-related and novel gene transcripts in
            reproductive and other tissues of female mice overexpressing
            spermidine/spermine N1-acetyltransferase (SSAT)
  JOURNAL   J Biol Chem 277 (5), 3647-3657 (2002)
   PUBMED   11709547
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK152037.1, BC083190.1 and AK136797.1.
            
            On Mar 25, 2009 this sequence version replaced NM_025344.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660819.274129.1, AK136797.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                AK152037.1         2-16
            16-1256             BC083190.1         1-1241
            1257-1507           AK136797.1         1256-1506
FEATURES             Location/Qualifiers
     source          1..1507
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 57.21 cM"
     gene            1..1507
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /note="eukaryotic translation initiation factor 3, subunit
                     F"
                     /db_xref="GeneID:66085"
                     /db_xref="MGI:MGI:1913335"
     exon            1..393
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..1103
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /EC_number="3.4.19.12"
                     /note="eukaryotic translation initiation factor 3, subunit
                     5 (epsilon); eIF3 p47; deubiquitinating enzyme eIF3f;
                     eIF-3-epsilon"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 3
                     subunit F"
                     /protein_id="NP_079620.2"
                     /db_xref="CCDS:CCDS21731.1"
                     /db_xref="GeneID:66085"
                     /db_xref="MGI:MGI:1913335"
                     /translation="MASPAVPANVPPATAAAAPAPVVTAAPASAPTPSTPAPTPAATP
                     AASPAPVSSDPAVAAPAAPGQTPASAPAPAQTPAPSQPGPALPGPFPGGRVVRLHPVI
                     LASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEVAVDMEFAKNM
                     YELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPNPIHLTVDTGLQHGRMSIK
                     AYVSTLMGVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMKTCFSPNRVIGLSSDLQQV
                     GGASARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIVPDDFETMLNSN
                     INDLLMVTYLANLTQSQIALNEKLVNL"
     exon            394..464
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /inference="alignment:Splign:2.1.0"
     exon            465..544
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /inference="alignment:Splign:2.1.0"
     exon            545..682
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /inference="alignment:Splign:2.1.0"
     exon            683..774
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /inference="alignment:Splign:2.1.0"
     exon            775..911
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1025
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1507
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1227..1232
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /note="hexamer: AATAAA"
     polyA_site      1256
                     /gene="Eif3f"
                     /gene_synonym="0610037M02Rik; Eif3s5"
                     /note="major polyA site"
ORIGIN      
        1 ctctctttct cggcaagatg gcttctccgg ccgtaccggc taatgtccct cctgccactg
       61 cagccgcagc cccggcgccg gtcgtcaccg cagccccggc ttcagccccg accccatcca
      121 cgccagctcc gacaccggct gcgactcccg ctgcgtcccc ggcgcccgtc tcgtctgatc
      181 ctgctgtagc tgcgcctgca gccccgggcc agaccccagc ctccgcgcca gccccagcgc
      241 agacgccggc gccttcgcag cccgggcccg ccctcccggg gcctttcccg ggcggccgcg
      301 tggtcaggct acaccccgtc attttggcct cgatcgtgga cagctacgaa cgccgcaacg
      361 agggagctgc ccgagttatt ggaaccctgt tgggaactgt tgacaagcac tcggtagaag
      421 tcaccaactg cttttcggtg ccacacaatg agtcagaaga tgaagtggct gttgacatgg
      481 aatttgctaa gaatatgtat gaattacata aaaaagtctc cccaaatgag ctcatcctag
      541 gctggtatgc cacaggccat gacatcacag aacactcagt gctgatccat gagtactaca
      601 gcagggaggc cccgaacccc attcacctca cggtggacac aggtctccag catgggcgca
      661 tgagcatcaa ggcctatgtc agcactttaa tgggtgtccc tgggaggacc atgggagtga
      721 tgttcacacc tctcacagtg aagtacgcgt attatgacac tgaacgcatt ggagttgacc
      781 tcatcatgaa gacgtgtttt agccccaacc gggtgattgg actctcaagt gacttacaac
      841 aagtgggagg ggcctcagct cgcatccagg atgctctaag cactgtatta cagtatgctg
      901 aggatgtgct gtctgggaaa gtgtctgctg acaacacggt gggccgcttc ttgatgagcc
      961 ttgtcaacca agtacccaag atagttcctg atgactttga gaccatgctc aacagcaaca
     1021 tcaatgacct gctgatggtg acctacctgg ccaatctcac ccagtcacag attgccctca
     1081 acgagaaact tgtaaacctg tgaatgagcc ccaagaggca cttgtgctgg tcgaggtttt
     1141 caccacaggg ctgagaccga agtggaggca aagggtttct ttgtggtctt gagtcacggt
     1201 gactcagtca gctgcttgtg actccaaata aacatagctt accttttgta aatgaacttt
     1261 atctgatgcg agtttattgt cggccaggag aaagaagcat gttcctgaac tcgcacggaa
     1321 gccagggagt gggcactgtg gggagaagct ggttatgttg gcatgactca cccacagtgg
     1381 ctgctcccac agcctaggct gcggtagtgt cacccagccc cacaccaagc agctttttct
     1441 tggcacagtg gtttacagtg atactttttt cttcttctaa cttaggataa tagcaaatgg
     1501 aatctcc
//
