LOCUS       NP_001398855             548 aa            linear   ROD 01-MAY-2025
DEFINITION  eukaryotic translation initiation factor 3 subunit D [Mus
            musculus].
ACCESSION   NP_001398855 XP_006521255
VERSION     NP_001398855.1
DBSOURCE    REFSEQ: accession NM_001411926.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 548)
  AUTHORS   Fujii,K., Zhulyn,O., Byeon,G.W., Genuth,N.R., Kerr,C.H., Walsh,E.M.
            and Barna,M.
  TITLE     Controlling tissue patterning by translational regulation of
            signaling transcripts through the core translation factor eIF3c
  JOURNAL   Dev Cell 56 (21), 2928-2937 (2021)
   PUBMED   34752747
REFERENCE   2  (residues 1 to 548)
  AUTHORS   Distler,U., Schmeisser,M.J., Pelosi,A., Reim,D., Kuharev,J.,
            Weiczner,R., Baumgart,J., Boeckers,T.M., Nitsch,R., Vogt,J. and
            Tenzer,S.
  TITLE     In-depth protein profiling of the postsynaptic density from mouse
            hippocampus using data-independent acquisition proteomics
  JOURNAL   Proteomics 14 (21-22), 2607-2613 (2014)
   PUBMED   25211037
REFERENCE   3  (residues 1 to 548)
  AUTHORS   Zeng,L., Wan,Y., Li,D., Wu,J., Shao,M., Chen,J., Hui,L., Ji,H. and
            Zhu,X.
  TITLE     The m subunit of murine translation initiation factor eIF3
            maintains the integrity of the eIF3 complex and is required for
            embryonic development, homeostasis, and organ size control
  JOURNAL   J Biol Chem 288 (42), 30087-30093 (2013)
   PUBMED   24003236
REFERENCE   4  (residues 1 to 548)
  AUTHORS   Masutani,M., Sonenberg,N., Yokoyama,S. and Imataka,H.
  TITLE     Reconstitution reveals the functional core of mammalian eIF3
  JOURNAL   EMBO J 26 (14), 3373-3383 (2007)
   PUBMED   17581632
REFERENCE   5  (residues 1 to 548)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL589650.20.
            
            On Sep 9, 2022 this sequence version replaced XP_006521255.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13948564.586086.1,
                                           SRR7345562.4810811.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 36.92 cM"
     Protein         1..548
                     /product="eukaryotic translation initiation factor 3
                     subunit D"
                     /note="eukaryotic translation initiation factor 3, subunit
                     7 (zeta); translation initiation factor eIF3 p66;
                     eIF-3-zeta; eukaryotic translation initiation factor 3
                     subunit 7"
                     /calculated_mol_wt=63858
     Region          4..521
                     /region_name="eIF-3_zeta"
                     /note="Eukaryotic translation initiation factor 3 subunit
                     7 (eIF-3); pfam05091"
                     /db_xref="CDD:461547"
     Site            53
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0007744|PubMed:23806337; propagated from
                     UniProtKB/Swiss-Prot (O70194.2)"
     Site            161
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O15371; propagated from
                     UniProtKB/Swiss-Prot (O70194.2)"
     Region          285..299
                     /region_name="RNA gate.
                     /evidence=ECO:0000250|UniProtKB:K7IM66"
                     /note="propagated from UniProtKB/Swiss-Prot (O70194.2)"
     Region          523..548
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (O70194.2)"
     Site            528
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:17242355,
                     ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (O70194.2)"
     Site            529
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:17242355; propagated from
                     UniProtKB/Swiss-Prot (O70194.2)"
     CDS             1..548
                     /gene="Eif3d"
                     /gene_synonym="66/67kDa; eIF3p66; Eif3s7"
                     /coded_by="NM_001411926.1:359..2005"
                     /db_xref="GeneID:55944"
                     /db_xref="MGI:MGI:1933181"
ORIGIN      
        1 makfmtpviq dnpsgwgpca vpeqfrdmpy qpfskgdrlg kvadwtgaty qdkrytnkys
       61 sqfgggsqya yfheedetsf qlvdtartqk tayqrnrmrf aqrnlrrdkd rrnmvqfnlq
      121 tlpksakqke rerirlqkkf qkqfgvrqkw dqksqkprds svevrsdwev keemdfpqlm
      181 kmrylevsep qdieccgale yydkafdrit trsekplrsi krifhtvttt ddpvirklak
      241 tqgnvfatda ilatlmsctr svyswdivvq rvgsklffdk rdnsdfdllt vsetaneppq
      301 degnsfnspr nlameatyin hnfsqqclrm grerynfpnp npfveddmdk neiasvayry
      361 rrwklgddid livrcehdgv mtgangevsf iniktlnewd srhcngvdwr qkldsqrgav
      421 iatelknnsy klarwtccal lagseylklg yvsryhvkds srhvilgtqq fkpnefasqi
      481 nlsvenawgi lrcvidicmk leegkylilk dpnkqvirvy slpdgtfsse edeedeeeee
      541 eeeeeeet
//
