LOCUS       NM_133916               2966 bp    mRNA    linear   ROD 11-MAR-2025
DEFINITION  Mus musculus eukaryotic translation initiation factor 3, subunit B
            (Eif3b), mRNA.
ACCESSION   NM_133916 XM_001476110
VERSION     NM_133916.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2966)
  AUTHORS   Perez,R.C., Yang,X., Familari,M., Martinez,G., Lovicu,F.J.,
            Hime,G.R. and de Iongh,R.U.
  TITLE     TOB1 and TOB2 mark distinct RNA processing granules in
            differentiating lens fiber cells
  JOURNAL   J Mol Histol 55 (1), 121-138 (2024)
   PUBMED   38165569
REFERENCE   2  (bases 1 to 2966)
  AUTHORS   Gregorio,I., Mereu,M., Contarini,G., Bello,L., Semplicini,C.,
            Burgio,F., Russo,L., Sut,S., Dall'Acqua,S., Braghetta,P.,
            Semenza,C., Pegoraro,E., Papaleo,F., Bonaldo,P. and Cescon,M.
  TITLE     Collagen VI deficiency causes behavioral abnormalities and cortical
            dopaminergic dysfunction
  JOURNAL   Dis Model Mech 15 (9) (2022)
   PUBMED   35946603
REFERENCE   3  (bases 1 to 2966)
  AUTHORS   Chen,X., Xue,G., Zhao,J., Zhang,Y., Zhang,S., Wang,W., Li,Y.,
            Yuan,J., He,L., Chan,C.Y., Liu,Y., Chen,W., Zhao,Y., Hu,P., Sun,H.,
            Kwok,C.K. and Wang,H.
  TITLE     Lockd promotes myoblast proliferation and muscle regeneration via
            binding with DHX36 to facilitate 5' UTR rG4 unwinding and Anp32e
            translation
  JOURNAL   Cell Rep 39 (10), 110927 (2022)
   PUBMED   35675771
REFERENCE   4  (bases 1 to 2966)
  AUTHORS   Fujii,K., Zhulyn,O., Byeon,G.W., Genuth,N.R., Kerr,C.H., Walsh,E.M.
            and Barna,M.
  TITLE     Controlling tissue patterning by translational regulation of
            signaling transcripts through the core translation factor eIF3c
  JOURNAL   Dev Cell 56 (21), 2928-2937 (2021)
   PUBMED   34752747
REFERENCE   5  (bases 1 to 2966)
  AUTHORS   Tang,X., Xie,X., Wang,X., Wang,Y., Jiang,X. and Jiang,H.
  TITLE     The Combination of piR-823 and Eukaryotic Initiation Factor 3 B
            (EIF3B) Activates Hepatic Stellate Cells via Upregulating TGF-beta1
            in Liver Fibrogenesis
  JOURNAL   Med Sci Monit 24, 9151-9165 (2018)
   PUBMED   30556540
  REMARK    GeneRIF: data illustrate a novel mechanism of piR-823 in HSC
            activities. The combination of piR-823 and EIF3B increased
            TGF-beta1 expression, which activates HSCs in liver fibrosis.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2966)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 2966)
  AUTHORS   Ballif,B.A., Villen,J., Beausoleil,S.A., Schwartz,D. and Gygi,S.P.
  TITLE     Phosphoproteomic analysis of the developing mouse brain
  JOURNAL   Mol Cell Proteomics 3 (11), 1093-1101 (2004)
   PUBMED   15345747
REFERENCE   8  (bases 1 to 2966)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 2966)
  AUTHORS   Koyanagi-Katsuta,R., Akimitsu,N., Hamamoto,H., Arimitsu,N.,
            Hatano,T. and Sekimizu,K.
  TITLE     Embryonic lethality of mutant mice deficient in the p116 gene
  JOURNAL   J Biochem 131 (6), 833-837 (2002)
   PUBMED   12038979
  REMARK    GeneRIF: results indicate that p116 plays an essential role in the
            early stages of mouse development[eIF3 p116]
REFERENCE   10 (bases 1 to 2966)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC131670.5.
            
            On or before Sep 5, 2008 this sequence version replaced
            XM_001476110.1, NM_133916.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK033722.1, AK170938.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-522               AC131670.5         134418-134939
            523-715             AC131670.5         140375-140567
            716-835             AC131670.5         141550-141669
            836-893             AC131670.5         141896-141953
            894-1022            AC131670.5         142130-142258
            1023-1180           AC131670.5         142523-142680
            1181-1312           AC131670.5         145165-145296
            1313-1379           AC131670.5         145375-145441
            1380-1426           AC131670.5         146084-146130
            1427-1637           AC131670.5         148037-148247
            1638-1710           AC131670.5         151361-151433
            1711-1833           AC131670.5         152398-152520
            1834-1912           AC131670.5         153429-153507
            1913-2051           AC131670.5         155026-155164
            2052-2177           AC131670.5         156099-156224
            2178-2255           AC131670.5         156850-156927
            2256-2364           AC131670.5         157237-157345
            2365-2481           AC131670.5         157433-157549
            2482-2966           AC131670.5         157987-158471
FEATURES             Location/Qualifiers
     source          1..2966
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 78.97 cM"
     gene            1..2966
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /note="eukaryotic translation initiation factor 3, subunit
                     B"
                     /db_xref="GeneID:27979"
                     /db_xref="MGI:MGI:106478"
     exon            1..522
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..2468
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /note="eukaryotic translation initiation factor 3, subunit
                     9 (eta); eIF-3-eta; eIF3 p116; eukaryotic translation
                     initiation factor 3 subunit 9"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 3
                     subunit B"
                     /protein_id="NP_598677.1"
                     /db_xref="CCDS:CCDS19819.1"
                     /db_xref="GeneID:27979"
                     /db_xref="MGI:MGI:106478"
                     /translation="MQDAENVAVPEAAEERAEPARQQPASESPPTDEAAGSGGSEVGQ
                     TEDAEEDAEAGPEPEVRAKPAAQSEEETATSPAASPTPQSAERSPSQEPSAPGKAEAV
                     GEQARGHPSAGAEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGD
                     VLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYPEEDGKT
                     KGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPF
                     KDLGNLRYWLEEAECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPK
                     GTYLATFHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQA
                     IIIWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKS
                     LKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHW
                     QKNGDYLCVKVDRTPKGTQGVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKF
                     AVLHGEAPRISVSFYHVKSNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGAL
                     AFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQK
                     NNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRR
                     TMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIP
                     LGSQE"
     exon            523..715
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            716..835
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            836..893
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            894..1022
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1180
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1181..1312
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1379
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1380..1426
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1637
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1638..1710
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1711..1833
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1834..1912
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1913..2051
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2052..2177
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..2255
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2256..2364
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2365..2481
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2482..2966
                     /gene="Eif3b"
                     /gene_synonym="D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116;
                     Eif3s9; PRT1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacttctggg agtcggaagc agggcggccg agccgggtga gaagcagcgc gggcccatgc
       61 aggacgctga gaacgtggcg gtgcccgagg cggccgagga gcgggctgag cccgcgaggc
      121 agcagccggc ctccgagtcg ccgccgacgg acgaggcggc agggtctggg gggtccgaag
      181 tggggcagac ggaagacgcc gaagaagacg ccgaggccgg accggagccc gaagtgaggg
      241 ccaagccggc ggcccaatcc gaagaggaaa cggcgacgag tccggccgcc tcgcccacgc
      301 cgcagtcggc ggagcggtcc ccgtcgcagg agccctctgc tcccgggaag gcagaggccg
      361 ttggcgagca ggcccggggg cacccctcgg ctggagcgga ggaggagggc gggtctgatg
      421 ggagcgcggc tgaggcggag ccgcgggctc tggagaacgg agaggcagat gagccctcct
      481 tcagcgaccc cgaggatttc gtagacgacg tgagcgagga agaactactt ggtgatgtac
      541 tcaaagatcg gcctcaggaa gcggacggga ttgactcggt gattgttgta gacaacgtcc
      601 ctcaggtggg gccagaccga cttgagaaac tcaaaaatgt catccacaag atcttctcca
      661 agtttgggaa aatcataaat gactattacc ctgaggagga cggaaagacg aaagggtaca
      721 tctttctgga gtacgcttct cccgcccatg ctgtggatgc tgtgaaaaac gccgatggct
      781 acaagctgga caagcagcac acgttccggg tcaacctctt caccgacttt gacaagtaca
      841 tgacgatcag cgatgagtgg gacattccag agaagcagcc tttcaaagac ctgggcaatt
      901 tgcgttactg gctggaagag gcagagtgta gagatcagta cagtgtgatt tttgagagcg
      961 gagaccggac gtccatcttc tggaatgacg tcaaggaccc agtctcaatt gaagaaagag
     1021 cgagatggac agagacgtac gtgcgctggt cccctaaggg tacctacctg gccactttcc
     1081 atcagcgggg tatcgccctc tggggagggg acaagttcaa gcagattcag aggttcagcc
     1141 accaaggcgt gcagctcatc gacttctctc cgtgtgaaag atacttggta acgttcagcc
     1201 ctctgatgga cactcaggat gaccctcagg ccatcatcat ctgggacatc ctcacgggcc
     1261 ataagaagag aggttttcac tgcgaaagct cagcccactg gcccatcttc aagtggagcc
     1321 atgatggcaa attctttgca agaatgaccc tggatactct tagcatctat gaaacacctt
     1381 ccatgggcct tttggacaag aagagtttga agatctctgg aattaaagac ttttcttggt
     1441 ctccgggtgg taacatcatt gctttttggg tgcctgaaga caaagatatt ccagccaggg
     1501 tgaccctgat gcagctcccc accagacagg agatccgagt gaggaatttg ttcaatgtgg
     1561 ttgattgcaa gctgcactgg cagaaaaatg gagattacct atgtgtaaaa gtggacagga
     1621 ctccgaaagg cacacaggga gttgtcacaa attttgaaat attccgaatg agggagaagc
     1681 aggtacctgt tgatgttgtt gagatgaaag aaaccatcat agcctttgcc tgggaaccca
     1741 atggcagtaa gtttgccgtg cttcatggtg aggcccctcg gatctctgtc tccttctacc
     1801 acgtgaagag caacgggaag attgaactca tcaagatgtt tgacaagcag caagccaaca
     1861 ccatcttctg gagtccccag gggcagttcg tggtgctggc cgggctgagg agcatgaacg
     1921 gtgccttggc gtttgtcgac acttcagact gcaccgtcat gaacattgca gagcactaca
     1981 tggcctccga tgttgaatgg gacccaactg gccgctacgt ggttacctct gtgtcgtggt
     2041 ggagccacaa ggtggacaat gcttactggc tgtggacctt ccaaggtcgc cttctgcaga
     2101 agaacaacaa ggaccgcttc tgccagctgc tctggagacc aaggccccca acactcctca
     2161 gccaggatca gataaagcaa attaaaaagg atctgaagaa gtactccaag atctttgagc
     2221 agaaggatcg cttgagccag tccaaagctt caaaggaact ggtggaaaga aggcggacca
     2281 tgatggagga cttccggcaa taccggaaaa tggcccagga actctacatg aagcagaaga
     2341 acgagcgtct agagctacga ggaggggtgg acactgacga gctggacagc aacgtggatg
     2401 actgggagga agagaccatt gagttttttg tcaccgagga agtcattcct ctgggaagtc
     2461 aggagtgatc tcagcactgt gtgtcaccgt gccgtgccca ggatccgagg ccacccttca
     2521 cggcgagcct cgtgctgggc tcttacctgt gctttcttgc tctggactgc gagtgcaccc
     2581 agggttcttc tatcccgaca cagctctgtg ccttcagccc caggtccaca gcggggacac
     2641 tcgagcctct gctctcacct tgccctgttt gggtttttat cagccgtgtc tgcattggag
     2701 cctcactgca gtgttcctgg tggctcctct taactcctgc tgctgtccat ggggtttcca
     2761 gagccttcac ctacagctca gtggggtttc cattcacgga cttgctgttc ctgtgggcca
     2821 gtgtcgtgtg gcctggagac catcaggagt ctgcacaccc accacttact tgtgccagaa
     2881 actctggagg cacccacacc tcccacctgt tcaggttgtg gcagcctctg tgcaggttgg
     2941 atgtggaaat aaaagcaacc ctgtgt
//
