LOCUS       NM_012011               1784 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus eukaryotic translation initiation factor 2, subunit 3,
            structural gene Y-linked (Eif2s3y), transcript variant 1, mRNA.
ACCESSION   NM_012011
VERSION     NM_012011.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1784)
  AUTHORS   Li,Y., Wu,W., Xu,W., Wang,Y., Wan,S., Chen,W., Yang,D., Zhang,M.,
            Wu,X., Yang,X., Du,X., Wang,C., Han,M., Chen,Y., Li,N. and Hua,J.
  TITLE     Eif2s3y alleviated LPS-induced damage to mouse testis and
            maintained spermatogenesis by negatively regulating Adamts5
  JOURNAL   Theriogenology 211, 65-75 (2023)
   PUBMED   37586163
  REMARK    GeneRIF: Eif2s3y alleviated LPS-induced damage to mouse testis and
            maintained spermatogenesis by negatively regulating Adamts5.
REFERENCE   2  (bases 1 to 1784)
  AUTHORS   Szakats,S., McAtamney,A., Cross,H. and Wilson,M.J.
  TITLE     Sex-biased gene and microRNA expression in the developing mouse
            brain is associated with neurodevelopmental functions and
            neurological phenotypes
  JOURNAL   Biol Sex Differ 14 (1), 57 (2023)
   PUBMED   37679839
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1784)
  AUTHORS   Song,Y., Chen,M., Zhang,Y., Li,J., Liu,B., Li,N., Chen,M., Qiao,M.,
            Wang,N., Cao,Y., Lu,S., Chen,J., Sun,W., Gao,F. and Wang,H.
  TITLE     Loss of circSRY reduces gammaH2AX level in germ cells and impairs
            mouse spermatogenesis
  JOURNAL   Life Sci Alliance 6 (2), e202201617 (2022)
   PUBMED   36414375
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1784)
  AUTHORS   Liu,W., Li,N., Zhang,M., Arisha,A.H. and Hua,J.
  TITLE     The Role of Eif2s3y in Mouse Spermatogenesis and ESC
  JOURNAL   Curr Stem Cell Res Ther 17 (8), 750-755 (2022)
   PUBMED   34727865
  REMARK    GeneRIF: The Role of Eif2s3y in Mouse Spermatogenesis and ESC.
REFERENCE   5  (bases 1 to 1784)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1784)
  AUTHORS   Ehrmann,I.E., Ellis,P.S., Mazeyrat,S., Duthie,S., Brockdorff,N.,
            Mattei,M.G., Gavin,M.A., Affara,N.A., Brown,G.M., Simpson,E.,
            Mitchell,M.J. and Scott,D.M.
  TITLE     Characterization of genes encoding translation initiation factor
            eIF-2gamma in mouse and human: sex chromosome localization, escape
            from X-inactivation and evolution
  JOURNAL   Hum Mol Genet 7 (11), 1725-1737 (1998)
   PUBMED   9736774
REFERENCE   7  (bases 1 to 1784)
  AUTHORS   Mazeyrat,S., Saut,N., Sargent,C.A., Grimmond,S., Longepied,G.,
            Ehrmann,I.E., Ellis,P.S., Greenfield,A., Affara,N.A. and
            Mitchell,M.J.
  TITLE     The mouse Y chromosome interval necessary for spermatogonial
            proliferation is gene dense with syntenic homology to the human
            AZFa region
  JOURNAL   Hum Mol Genet 7 (11), 1713-1724 (1998)
   PUBMED   9736773
REFERENCE   8  (bases 1 to 1784)
  AUTHORS   Ashley,T., Lieman,J. and Ward,D.C.
  TITLE     Multicolor FISH with a telomere repeat and Sry sequences shows that
            Sxr (Sex reversal) in the mouse is a new type of chromosome
            rearrangement
  JOURNAL   Cytogenet Cell Genet 71 (3), 217-222 (1995)
   PUBMED   7587380
REFERENCE   9  (bases 1 to 1784)
  AUTHORS   Jackson-Grusby,L., Kuo,A. and Leder,P.
  TITLE     A variant limb deformity transcript expressed in the embryonic
            mouse limb defines a novel formin
  JOURNAL   Genes Dev 6 (1), 29-37 (1992)
   PUBMED   1339380
REFERENCE   10 (bases 1 to 1784)
  AUTHORS   Mather,P.B. and Holmes,R.S.
  TITLE     Biochemical genetics of aldehyde dehydrogenase isozymes in the
            mouse: evidence for stomach- and testis-specific isozymes
  JOURNAL   Biochem Genet 22 (11-12), 981-995 (1984)
   PUBMED   6543304
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY711372.1, AK009448.1, AC145392.2 and AI661184.1.
            
            On Oct 19, 2017 this sequence version replaced NM_012011.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ006584.1, AK153974.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                BY711372.1         2-39
            39-794              AK009448.1         27-782
            795-848             AC145392.2         13640-13693         c
            849-1776            AK009448.1         837-1764
            1777-1784           AI661184.1         2-9                 c
FEATURES             Location/Qualifiers
     source          1..1784
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="Y"
                     /map="Y"
     gene            1..1784
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /note="eukaryotic translation initiation factor 2, subunit
                     3, structural gene Y-linked"
                     /db_xref="GeneID:26908"
                     /db_xref="MGI:MGI:1349430"
     exon            1..91
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     exon            92..155
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     exon            156..283
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     exon            284..405
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     exon            406..500
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     exon            501..659
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     exon            660..794
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     exon            795..889
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     exon            890..1034
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1204
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1377
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     exon            1378..1784
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1759..1764
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /note="hexamer: AATAAA"
     polyA_site      1784
                     /gene="Eif2s3y"
                     /gene_synonym="Eif-2gy; Spy; Tfy"
                     /note="major polyA site"
ORIGIN      
        1 acttccttct ttcgtgagca agatggcggg cggagaagcc ggtgtcactc tcgggcagcc
       61 gcatctttct cgtcaggatc ttgccacttt ggatgttacc aagttgactc cgctttcacg
      121 tgaaattatc agcagacaag ccacaattaa tataggcaca attggtcatg ttgctcatgg
      181 aaaatctaca gttgtaaaag ccatttctgg tgttcacact gtccgattca aaaatgaact
      241 agaaaggaat attaccataa aacttggata tgctaatgcc aaaatttata agcttgatga
      301 ctcaagttgt cctcgaccag aatgttacag atcttgtgga agtagtacac ctgatgagtt
      361 tccttcagat attccaggga ccaaaggaaa cttcagacta gtcagacatg tttcctttgt
      421 tgattgtcct ggtcatgata ttttgatggc aactatgctg aatggggcag cagtgatgga
      481 tgcagctctt ctgttgatag ctggtaatga atcttgtcct caacctcaga cttctgaaca
      541 cctggctgcc attgaaatta tgaagctaaa acatattttg attctgcaaa ataaaattga
      601 tttggtgaaa gaaagccagg ctaaagaaca gtatgaacag atacttgcat ttgtacaggg
      661 tacagtagcc gaaggagctc ctattattcc aatttctgct cagttaaaat acaatattga
      721 agttgtatgt gagtatatag taaagaaaat tccagtacct ctaagagact ttacttcaga
      781 accccgactt attgttattc ggtcttttga tgttaacaaa cctggctgtg aagttgatga
      841 ccttaaaggg ggtgtagctg gtggtagtat tttaaaaggc gtattaaagg tgggacaaga
      901 gatagaagtg agacctggta ttgtttctaa agacggagaa gggaagctta tgtgtaaacc
      961 aatcttttcc aagattgtat ccctttttgc agaacacaat gatcttcagt atgctgctcc
     1021 aggtggtctt attggagttg gaacaaaaat tgacccaacg ttatgccgag cagatagaat
     1081 ggttgggcag gtccttggtg ctgttggagc attacctgag atattcacag agttagaaat
     1141 ttcctacttc ctactgagac ggctcctagg tgtacgtaca gaaggagaca agaaagcagc
     1201 aaaagttcaa aagctatcca agaatgaagt actcatggtg aacatagggt ccttgtctac
     1261 aggaggcaga gttagtgcag tcaaggcaga tttgggtaaa attgttctaa ccaatccagt
     1321 atgcacagaa gtaggagaaa aaattgctct aagccgacga gttgagaaac actggcgttt
     1381 aattggttgg ggccagataa gaagaggcgt gactatcaag ccaacaatag atgatgaatg
     1441 agatgataca tttggatgaa accaggaatt ttttcataac agtcttagag atattttcaa
     1501 atctaaaaag taggacatct aaagaaggaa ataaatttca cagcttatta ttatattagt
     1561 aaaaattgcc aggttatttt cattttcagt agaaaaaaat tgatgtctgt aaaaaaaaat
     1621 gacaaacttc ttgatacatt taatctgcaa ttcaacaaat agtattattg ttgtagcttg
     1681 atagttaaca actgttgctg tgcaccactg aacttacagt aaagaaagtt tttcttatgt
     1741 ttgaaggatt gttactctaa taaaaacttg aaggctggat tcaa
//
