LOCUS       NM_001136070            1976 bp    mRNA    linear   ROD 16-DEC-2022
DEFINITION  Mus musculus eukaryotic translation initiation factor 2D (Eif2d),
            transcript variant 1, mRNA.
ACCESSION   NM_001136070
VERSION     NM_001136070.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1976)
  AUTHORS   Malnar-Dragojevic D, Trachtulec Z and Vincek V.
  TITLE     Assignment of the mouse ligatin gene (Lgtn) to chromosome 1F by in
            situ hybridization
  JOURNAL   Genomics 40 (1), 192-193 (1997)
   PUBMED   9070942
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK139052.1.
            
            [WARNING] On Apr 28, 2023 this sequence was replaced by
            NM_001136070.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK139052.1, AK166085.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..1976
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 56.9 cM"
     gene            1..1976
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /note="eukaryotic translation initiation factor 2D"
                     /db_xref="GeneID:16865"
                     /db_xref="MGI:MGI:109342"
     exon            1..219
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     CDS             164..1876
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ligatin"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 2D
                     isoform 1"
                     /protein_id="NP_001129542.1"
                     /db_xref="CCDS:CCDS48354.1"
                     /db_xref="GeneID:16865"
                     /db_xref="MGI:MGI:109342"
                     /translation="MFAKAFRVKSNTAIKGSDRRKLRADVTAAFPALGTDQISELIPG
                     KEELNVVKLYVHKGDSVTVYTSGGNPILFELEKNLYPTVYTLWAYPDILPTFITWPLV
                     LEKLVGGADLMLPGVVVPPTGLPQVQQGDLCAIALVGNRAPVAIGVAAMSTAQMLASG
                     LKGKGVSVLHTYQDHLWRSGDKSSPPAIAPLDPTDSCEEKVHLGLQGNLKSLTLDGEE
                     ENGQVPLREASEDTSSRAPSQDSLDGKPLQEQMDDLLLRCFLHALKSRVKKADLPLLT
                     STLLGSHMFSCCPEGQQLDIKKSSYKKLSKFLQHMQQEQIVQVKELSKGVESIVAVDW
                     RHPRITSFVIPEPSLTSQTVQEVSREQPYLPPDIKSLYCVPANMTQLFLESGHKKGST
                     LEGSEVRKIITDYAKRNRLVDADNRNLVKLDPILCDCILEKNEQHLVTKLPWDCLLTR
                     CLKNMQPAYQVTFPGQEPILKKGKLCPIDITLALKTYNKKVTVVRNLETYGLDPCSVA
                     AILQQRCQASTIVSPAPGAKDSLQVQVQGNQIHHLGQLLLEEYRLPGKYIQGLEKAPK
                     PGKK"
     exon            220..410
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            411..494
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            495..585
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            586..693
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            694..908
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            909..1026
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1072
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            1073..1176
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1326
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1416
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1512
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1633
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            1634..1808
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     exon            1809..1976
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1957..1962
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /note="putative"
     polyA_site      1976
                     /gene="Eif2d"
                     /gene_synonym="D1Ertd5e; Lgtn"
                     /note="putative"
ORIGIN      
        1 agcatcaggg ctagggccgg gttcctagca ggctgttttt tggcgccgag tctcagcatg
       61 gctgcctcca gggttgaggg tccgggagcc gccactcctt cgttttgttg accgcccctg
      121 gcgtctgtgc tcttcttgtc tttcctgagc tactccagca gacatgttcg ctaaggcctt
      181 tcgggtcaag tccaacacag ccatcaaggg ctcggacagg agaaagctcc gggccgatgt
      241 gacagctgct ttccctgccc tgggaacaga tcagatctct gaattgatac ctggaaagga
      301 agagctaaat gttgtgaagt tgtatgttca caaaggggat tcggtgactg tgtacacgag
      361 tggtggtaac cccatcctat ttgaactgga gaaaaatttg tatccaacag tgtacacact
      421 gtgggcctat ccggatattc taccaacttt tataacatgg cctctggtat tggaaaaact
      481 ggtcggggga gcagatttga tgctgccagg ggtagtggtg ccccctactg gtcttcctca
      541 agtacagcaa ggcgacctct gtgccattgc cttggtgggg aacagagcgc ccgttgcaat
      601 tggagtggcc gccatgtcca cagctcagat gctggcttca ggcctgaagg gaaaaggtgt
      661 ctctgtgctc cacacttatc aggaccactt gtggagatct ggagacaagt cctctccacc
      721 tgccattgcc ccactggacc ccacagatag ctgcgaagag aaggtgcacc ttggtctgca
      781 gggaaacctg aagagcctga ccctggacgg agaggaggag aacgggcagg ttcctctccg
      841 agaagcctct gaggacacca gctccagggc cccgagccag gattccttgg acggcaagcc
      901 ccttcaggaa caaatggacg atctgttact gcggtgcttc cttcatgccc tgaagagtcg
      961 agtcaagaaa gctgacctcc cgttgctcac cagcactctc cttggcagtc acatgttctc
     1021 ctgctgtcct gaaggacagc aactggatat aaagaagtca agctataaaa agctctctaa
     1081 gttcctgcag cacatgcagc aggagcagat tgtccaggtc aaggagctga gcaaaggggt
     1141 ggagagcatt gtggctgtgg actggaggca cccgaggatc acgtctttcg tcatccccga
     1201 gccttccctg acttcccaga ctgtccagga agttagcagg gaacagccct atctccctcc
     1261 agatataaaa tccctctact gtgtcccagc caacatgacc cagctcttcc tggagtctgg
     1321 ccacaagaag gggagcaccc ttgagggcag tgaggtccga aagatcatca cggactatgc
     1381 caagagaaac agactggtgg atgcagacaa cagaaatctg gtgaagttgg atcctatctt
     1441 atgtgactgc atcttagaga aaaatgagca gcacttggtc acgaagctcc catgggactg
     1501 tctcctgacc aggtgtttga aaaatatgca gcctgcctac caagtaacat ttcctggcca
     1561 ggaacccatt ctaaagaaag ggaaactctg tccaattgat atcacccttg cactgaagac
     1621 ctataataaa aaggtgactg tggtccggaa cttggagacc tatggtctag atccgtgctc
     1681 agtggccgcc attctccagc agcgatgtca ggcaagcacc atcgtctctc ctgcccctgg
     1741 ggccaaagac agtctgcagg tgcaggtcca gggaaaccag atccaccacc ttggccagct
     1801 actgcttgaa gagtatcggc tccctggaaa atacatccaa ggcctagaaa aggcccccaa
     1861 acctggcaag aagtgacaga ctcattttat gcagtggacc ccatgggaac ccaggttctg
     1921 agctggtaac tgatacgagc agttttggct tttgcaaata aaaactgtaa ttcttt
//
