LOCUS       NM_026892                917 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus eukaryotic translation initiation factor 1B (Eif1b),
            mRNA.
ACCESSION   NM_026892
VERSION     NM_026892.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 917)
  AUTHORS   Salamon,I., Park,Y., Miskic,T., Kopic,J., Matteson,P., Page,N.F.,
            Roque,A., McAuliffe,G.W., Favate,J., Garcia-Forn,M., Shah,P.,
            Judas,M., Millonig,J.H., Kostovic,I., De Rubeis,S., Hart,R.P.,
            Krsnik,Z. and Rasin,M.R.
  TITLE     Celf4 controls mRNA translation underlying synaptic development in
            the prenatal mammalian neocortex
  JOURNAL   Nat Commun 14 (1), 6025 (2023)
   PUBMED   37758766
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 917)
  AUTHORS   Zurkirchen,L., Varum,S., Giger,S., Klug,A., Hausel,J., Bossart,R.,
            Zemke,M., Cantu,C., Atak,Z.K., Zamboni,N., Basler,K. and Sommer,L.
  TITLE     Yin Yang 1 sustains biosynthetic demands during brain development
            in a stage-specific manner
  JOURNAL   Nat Commun 10 (1), 2192 (2019)
   PUBMED   31097699
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 917)
  AUTHORS   Zhu,F., Yan,P., Zhang,J., Cui,Y., Zheng,M., Cheng,Y., Guo,Y.,
            Yang,X., Guo,X. and Zhu,H.
  TITLE     Deficiency of TPPP2, a factor linked to oligoasthenozoospermia,
            causes subfertility in male mice
  JOURNAL   J Cell Mol Med 23 (4), 2583-2594 (2019)
   PUBMED   30680919
  REMARK    GeneRIF: Deficiency of TPPP2 might affect the translation of
            specific proteins, such as eEf1b, altering the structure and
            function of sperm mitochondria, and resulting in decreased sperm
            count, motility and fertility.
REFERENCE   5  (bases 1 to 917)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 917)
  AUTHORS   Tachikawa,K., Sasaki,S., Maeda,T. and Nakajima,K.
  TITLE     Identification of molecules preferentially expressed beneath the
            marginal zone in the developing cerebral cortex
  JOURNAL   Neurosci Res 60 (2), 135-146 (2008)
   PUBMED   18055048
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AI154212.1, AK013965.1 and AK005192.1.
            
            On Dec 2, 2008 this sequence version replaced NM_026892.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005192.1, BY712983.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                AI154212.1         7-33
            28-266              AK013965.1         1-239
            267-917             AK005192.1         234-884
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 71.67 cM"
     gene            1..917
                     /gene="Eif1b"
                     /gene_synonym="1500010M16Rik; 3110001N14Rik; Gc20"
                     /note="eukaryotic translation initiation factor 1B"
                     /db_xref="GeneID:68969"
                     /db_xref="MGI:MGI:1916219"
     exon            1..236
                     /gene="Eif1b"
                     /gene_synonym="1500010M16Rik; 3110001N14Rik; Gc20"
                     /inference="alignment:Splign:2.1.0"
     CDS             206..547
                     /gene="Eif1b"
                     /gene_synonym="1500010M16Rik; 3110001N14Rik; Gc20"
                     /note="translation factor sui1 homolog"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 1b"
                     /protein_id="NP_081168.1"
                     /db_xref="CCDS:CCDS23628.1"
                     /db_xref="GeneID:68969"
                     /db_xref="MGI:MGI:1916219"
                     /translation="MSTIQNLQSFDPFADATKGDDLLPAGTEDYIHIRIQQRNGRKTL
                     TTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLLEVGI
                     VKEEQLKVHGF"
     exon            237..400
                     /gene="Eif1b"
                     /gene_synonym="1500010M16Rik; 3110001N14Rik; Gc20"
                     /inference="alignment:Splign:2.1.0"
     exon            401..502
                     /gene="Eif1b"
                     /gene_synonym="1500010M16Rik; 3110001N14Rik; Gc20"
                     /inference="alignment:Splign:2.1.0"
     exon            503..917
                     /gene="Eif1b"
                     /gene_synonym="1500010M16Rik; 3110001N14Rik; Gc20"
                     /inference="alignment:Splign:2.1.0"
     regulatory      880..885
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Eif1b"
                     /gene_synonym="1500010M16Rik; 3110001N14Rik; Gc20"
                     /note="hexamer: AATAAA"
     polyA_site      903
                     /gene="Eif1b"
                     /gene_synonym="1500010M16Rik; 3110001N14Rik; Gc20"
                     /note="major polyA site"
ORIGIN      
        1 aaatacgcgg cgccggccat tttgtgcgag aagccgcagc gccgcctccc tgctcgcgcc
       61 ccaccgccgc ctccgcgtct tcctgcgccc cgggcttccg ccgcttcatt gatttccgtt
      121 tctcgccgct gcagcctcct gacacggtga tccgggcggg ccccgcggga attctatcct
      181 ctcaccggcc tcacactagt gtcgcatgtc cactatccag aacctccaat ctttcgaccc
      241 ctttgctgat gcaactaagg gcgacgactt actcccggca gggactgagg actacattca
      301 tataaggatc cagcagcgca acggcaggaa gacgctgacc actgtgcagg gcattgcgga
      361 cgattatgac aaaaagaaac ttgtgaaagc tttcaaaaag aaatttgcct gcaatggaac
      421 tgtgattgaa caccctgagt acggagaggt tattcagctt caaggggacc aaaggaagaa
      481 catctgccag tttcttctgg aggttggcat cgtcaaggag gagcagctga aggttcacgg
      541 gttctaagat gaacccaagc gtggcgagtt tcttaaatgg ttttgttctc taactcagtt
      601 tggctgcctc gggagatgat tctttacagt aaacgacaga ctttgcgttt atttaatcat
      661 tcagacttcc actcacacct gcatggctac agaaaacacg gggtatgtag gctcctgagt
      721 cataaggaaa tcgcggtgag atgggaacga agcccgagtc cgtcctaaca tgtttccaat
      781 ggaaaaggtt ttgttgtgag tgtttgttgt tagttttatt ttcacttgac tgttaaatgt
      841 ttttgttgtt gtattaaacc atgtatgttg cggcttaaca ataaaaagaa agtgtgcatc
      901 ctttatgagc gctgacc
//
