LOCUS       NM_027236               2469 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus eukaryotic translation initiation factor 1A domain
            containing (Eif1ad), mRNA.
ACCESSION   NM_027236 XM_129120
VERSION     NM_027236.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2469)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2469)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC122861.4.
            
            On Mar 21, 2007 this sequence version replaced NM_027236.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024640.1, AK158977.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-398               AC122861.4         101318-101715
            399-617             AC122861.4         102563-102781
            618-726             AC122861.4         102927-103035
            727-835             AC122861.4         103122-103230
            836-883             AC122861.4         103400-103447
            884-2469            AC122861.4         104431-106016
FEATURES             Location/Qualifiers
     source          1..2469
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 4.31 cM"
     gene            1..2469
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
                     /note="eukaryotic translation initiation factor 1A domain
                     containing"
                     /db_xref="GeneID:69860"
                     /db_xref="MGI:MGI:1917110"
     exon            1..398
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
                     /inference="alignment:Splign:2.1.0"
     exon            399..617
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
                     /inference="alignment:Splign:2.1.0"
     CDS             531..1043
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
                     /note="eukaryotic translation initiation factor 1A
                     domain-containing protein"
                     /codon_start=1
                     /product="probable RNA-binding protein EIF1AD"
                     /protein_id="NP_081512.1"
                     /db_xref="CCDS:CCDS29459.1"
                     /db_xref="GeneID:69860"
                     /db_xref="MGI:MGI:1917110"
                     /translation="MSQASKRKHVVQEVLGEHMVPSDHQQIVKVLRTPGNNLHEVETA
                     QGQRFLVSMPSKYRKNIWIKRGDFLIVDPIEEGEKVKAEISFVLCKNHVRSLQKEGHW
                     PEAFSEVAEKQNNMNRESQPELPAEPQLSGEGSSSEDDSDLFVNTNHRQYHESEEESE
                     EDEEEEEEAA"
     exon            618..726
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
                     /inference="alignment:Splign:2.1.0"
     exon            727..835
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
                     /inference="alignment:Splign:2.1.0"
     exon            836..883
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
                     /inference="alignment:Splign:2.1.0"
     exon            884..2469
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1180..1185
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
                     /note="hexamer: ATTAAA"
     polyA_site      1206
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
                     /note="major polyA site"
     regulatory      2440..2445
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
                     /note="hexamer: AATAAA"
     polyA_site      2465
                     /gene="Eif1ad"
                     /gene_synonym="2010003J03Rik; Eif1ad1"
ORIGIN      
        1 gcttttgttt ctccagcggc ccttccggtc tgtgggatcg agacctccga ggagaatgcg
       61 ttttcctgcc ccgcactcgg aacttaggct tgcctcactt gatggaggga agagttaaag
      121 ggacggacga agagggggcg ggaaatccgg aggacctctg agcgccccgg aatcgcaatt
      181 cccggcgcgg tttcctcagg tctgtcacct cagaccggca gacgggaggg aggaacaacg
      241 gaggattggg gccgagcgtc cagaccggcg ttaccgtcgg ggccacctgc aggtcacagt
      301 tgtttgctct ttggtccctc gctgtcgagg cgcgtcgtgg acgagctact gtcgccgtca
      361 acctggaaag cggagcgtgc tggtgtggcg ccgagcgggg cgaggtggca ctttttcgta
      421 taaggctgct tctcttgaaa gcagtcctgg cttctaaggc tggcatccaa ataattctgg
      481 aagaagaact gacagtctgt gcaccctaac aaccctggac agaaaccagc atgtctcagg
      541 ccagcaagag gaagcatgtg gtgcaggagg tgctggggga gcacatggtg ccttctgacc
      601 accagcaaat agtgaaagtc ctcaggactc ctgggaacaa tctgcatgag gtggaaacag
      661 cacaggggca gcgcttcctg gtgagcatgc cctccaaata ccgcaagaac atctggatca
      721 agagagggga tttcctcatt gttgacccta ttgaagaagg agaaaaagtg aaggctgaga
      781 tctcttttgt gctctgcaag aaccatgtcc gctctctaca gaaggagggt cactggcctg
      841 aggccttctc tgaggtagct gagaaacaga acaatatgaa cagagagagt caaccagaac
      901 tccctgctga gccacagctg tcaggagaag ggtcaagttc tgaagatgat tctgacctct
      961 ttgtcaacac caatcacaga cagtatcatg agagtgagga ggagagtgaa gaagacgagg
     1021 aggaggagga ggaggcagcc tgagccccag gacccacttc tctatttgct cagggactac
     1081 cccttggctt ttctgggctt ggacatcccc agggtgccct gcagatcttt tcctttggat
     1141 gaggacaaag atggcccctt tctgaactga cctaaaagaa ttaaacccct ggtgggtgat
     1201 gacttacact ggtgtctgag tggctctctg tggagggaag ctcatggtga agtctcttcg
     1261 gtggtggaag ccttggtcac gtatgaggag aatggaaagg aaatggtttg gcctaactct
     1321 gctgcatgtg tctggttcac agtacctctc tgtacacttt atgcctcgct ctacactgtg
     1381 ccttactggg tcttcttcat acctgctttc gtttagtcgt gattccaata gttaagcttg
     1441 ttgcctagga cctagtactc acttgcctct taagcacagc tgaggacaaa cctcttggtg
     1501 ccttgttgtc ccttattgca acagtgcata ctacctgctg ccatacaaac aacacccatg
     1561 caccctgtct ctcttcacct taggcacctg tcatttccag aatgtgtctg tggtcaggat
     1621 aacctcctta ccgtctcatg tttttttaat ttttccaatt tcctcagggt ataaatttcc
     1681 tgtaatcttg agatggtctg taacgtaggt ttgcttggga atcactgtat agcctaggct
     1741 gaccaactca atggctgtcc tgcccacagg catgaacctg tggggctcct aaccttttat
     1801 tagaggctat tgcaacgccc ttaccccttg tacctcagca tcaaaaggct gatcgtggca
     1861 actcagacct ctgctcatga ctgcctccat tcatttactc actctcattg ccttagttca
     1921 cagatccttc agtagcccag gtactcacta aacttcgagc ttctgtgaac tgtgtctgtc
     1981 ctcgcttgtt ggaaggcttt tgcttctggc tatacactgc tagcattaac ccagcccctg
     2041 ctgaatacca ttgaaattga cctctcagct cagtattgcc cctgctggtc atttgctcca
     2101 tcccacagtg gaactcttca accctgttgc ccactcctaa tgtgtgtgtg tgtgtgtgtg
     2161 tgtgtgtgtg tgtgtgtgtg ttttccgtgt gcacttgtac taatggaact tctactttgg
     2221 agcctttctg agggattttg tttttctgtt gtgggtagtt ggttgagtgt ggaggcatgt
     2281 attagcttca tatgctatat agaatctctt atttttgaac aaatcttatg atcataccct
     2341 ctctggcttt catttatgtc cgtcatgttt gctttttgtg atagtaaatg tatacttggg
     2401 tatacacatg tataaaatac agatgtatat acatggaaaa ataaactaga tgggttaaag
     2461 atgaaccta
//
