LOCUS       NM_019397               2700 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus EGF-like-domain, multiple 6 (Egfl6), mRNA.
ACCESSION   NM_019397
VERSION     NM_019397.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2700)
  AUTHORS   Wilson,C.L., Hung,C.F., Burkel,B.M., Ponik,S.M., Gharib,S.A. and
            Schnapp,L.M.
  TITLE     Nephronectin is required to maintain right lung lobar separation
            during embryonic development
  JOURNAL   Am J Physiol Lung Cell Mol Physiol 324 (3), L335-L344 (2023)
   PUBMED   36719987
REFERENCE   2  (bases 1 to 2700)
  AUTHORS   Angelozzi,M., Pellegrino da Silva,R., Gonzalez,M.V. and Lefebvre,V.
  TITLE     Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly
            proliferative, and myofibroblast-like osteodermal progenitors
  JOURNAL   Cell Rep 40 (2), 111045 (2022)
   PUBMED   35830813
REFERENCE   3  (bases 1 to 2700)
  AUTHORS   Chen,K., Liao,S., Li,Y., Jiang,H., Liu,Y., Wang,C., Kuek,V.,
            Kenny,J., Li,B., Huang,Q., Hong,J., Huang,Y., Chim,S.M.,
            Tickner,J., Pavlos,N.J., Zhao,J., Liu,Q., Qin,A. and Xu,J.
  TITLE     Osteoblast-derived EGFL6 couples angiogenesis to osteogenesis
            during bone repair
  JOURNAL   Theranostics 11 (20), 9738-9751 (2021)
   PUBMED   34815781
  REMARK    GeneRIF: Osteoblast-derived EGFL6 couples angiogenesis to
            osteogenesis during bone repair.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2700)
  AUTHORS   Bian,Q., Cheng,Y.H., Wilson,J.P., Su,E.Y., Kim,D.W., Wang,H.,
            Yoo,S., Blackshaw,S. and Cahan,P.
  TITLE     A single cell transcriptional atlas of early synovial joint
            development
  JOURNAL   Development 147 (14) (2020)
   PUBMED   32580935
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2700)
  AUTHORS   Abbasi,F., Kodani,M., Emori,C., Kiyozumi,D., Mori,M., Fujihara,Y.
            and Ikawa,M.
  TITLE     CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are
            Dispensable for Female Fertility in Mice
  JOURNAL   Cells 9 (4), 821 (2020)
   PUBMED   32231122
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2700)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   7  (bases 1 to 2700)
  AUTHORS   Manabe,R., Tsutsui,K., Yamada,T., Kimura,M., Nakano,I., Shimono,C.,
            Sanzen,N., Furutani,Y., Fukuda,T., Oguri,Y., Shimamoto,K.,
            Kiyozumi,D., Sato,Y., Sado,Y., Senoo,H., Yamashina,S., Fukuda,S.,
            Kawai,J., Sugiura,N., Kimata,K., Hayashizaki,Y. and Sekiguchi,K.
  TITLE     Transcriptome-based systematic identification of extracellular
            matrix proteins
  JOURNAL   Proc Natl Acad Sci U S A 105 (35), 12849-12854 (2008)
   PUBMED   18757743
REFERENCE   8  (bases 1 to 2700)
  AUTHORS   Osada,A., Kiyozumi,D., Tsutsui,K., Ono,Y., Weber,C.N., Sugimoto,N.,
            Imai,T., Okada,A. and Sekiguchi,K.
  TITLE     Expression of MAEG, a novel basement membrane protein, in mouse
            hair follicle morphogenesis
  JOURNAL   Exp Cell Res 303 (1), 148-159 (2005)
   PUBMED   15572035
  REMARK    GeneRIF: MAEG may play a role as a mediator regulating
            epithelial-mesenchymal interaction through binding to RGD-binding
            integrins including alpha8beta1 during hair follicle development.
REFERENCE   9  (bases 1 to 2700)
  AUTHORS   Buchner,G., Broccoli,V., Bulfone,A., Orfanelli,U., Gattuso,C.,
            Ballabio,A. and Franco,B.
  TITLE     MAEG, an EGF-repeat containing gene, is a new marker associated
            with dermatome specification and morphogenesis of its derivatives
  JOURNAL   Mech Dev 98 (1-2), 179-182 (2000)
   PUBMED   11044626
REFERENCE   10 (bases 1 to 2700)
  AUTHORS   Buchner,G., Orfanelli,U., Quaderi,N., Bassi,M.T., Andolfi,G.,
            Ballabio,A. and Franco,B.
  TITLE     Identification of a new EGF-repeat-containing gene from human Xp22:
            a candidate for developmental disorders
  JOURNAL   Genomics 65 (1), 16-23 (2000)
   PUBMED   10777661
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL672174.8.
            
            On Apr 28, 2007 this sequence version replaced NM_019397.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ245672.1, AK078534.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-261               AL672174.8         187459-187719       c
            262-374             AL672174.8         170412-170524       c
            375-467             AL672174.8         164945-165037       c
            468-587             AL672174.8         158973-159092       c
            588-707             AL672174.8         154428-154547       c
            708-842             AL672174.8         150826-150960       c
            843-965             AL672174.8         148424-148546       c
            966-1286            AL672174.8         140417-140737       c
            1287-1367           AL672174.8         138203-138283       c
            1368-1469           AL672174.8         133975-134076       c
            1470-1735           AL672174.8         129317-129582       c
            1736-2700           AL672174.8         125010-125974       c
FEATURES             Location/Qualifiers
     source          1..2700
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 77.66 cM"
     gene            1..2700
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /note="EGF-like-domain, multiple 6"
                     /db_xref="GeneID:54156"
                     /db_xref="MGI:MGI:1858599"
     exon            1..261
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
     exon            262..374
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
     exon            375..467
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
     exon            468..587
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
     exon            588..707
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
     exon            708..842
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
     exon            843..965
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1286
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1367
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
     exon            1368..1469
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1735
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
     exon            1736..2700
                     /gene="Egfl6"
                     /gene_synonym="Maeg"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctccagggcg cccccagcca ctcacagctc caaacgttcc ccagctctcc acctctgcgc
       61 gggctgccac agagcctgcc agctgcgcgc aaaaccaagg tcctgaccag cgaagcagag
      121 aagaggcggt ggcccctctg tttcgtaggt cctgaggggc tcaggacaag aaaggagccc
      181 acccccggcc agtatgcagc cgccctgggg cctggcgctt cctctgctgc tcccctgggt
      241 gacaggtgga gtagggacca gtccatggga ttatgggttg tcagcactgg cacaccagcc
      301 tggggtctgt cagtatggaa ctaagatggc ctgctgctat ggctggaaaa ggaacaacaa
      361 gggagtatgc gaagctatgt gtgagcccag gtgcaagttc ggtgagtgtg tgggaccgaa
      421 taaatgtaga tgctttccag gatacaccgg gaagacctgc actcaagatg tgaatgagtg
      481 tggagtcaaa ccccggccgt gccagcacag atgtgtgaat acacatggta gctacaaatg
      541 cttttgcctc agcggccaca tgcttctacc agatgctaca tgttcaaact ccaggacgtg
      601 tgccagacta aactgccagt acggctgtga agacacagag gaagggccac ggtgtgtgtg
      661 tccatcctct ggcctccgcc tgggcccaaa tggaagagta tgcctagata tcgatgaatg
      721 tgcgtctagc aaagcagtct gcccttccaa tcgaagatgc gtgaacacgt ttggaagcta
      781 ctactgcaaa tgtcacattg gttttgagct gaaatatatc ggtcgccgat atgattgtgt
      841 agatataaat gagtgtgctc tgaataccca tccgtgcagc ccccatgcca attgcctcaa
      901 tacccgagga tccttcaagt gcaaatgcaa gcagggatat aggggcaatg gcctgcagtg
      961 ttctgtgatc cctgaacatt ctgtgaagga aatactcaca gcacctggga ccatcaaaga
     1021 ccgaatcaag aagttactgg ctcacaagcg caccatgaag aaaaaggtga aactaaaaat
     1081 ggtcacccca agacccgcca gtacacgtgt ccctaaggtc aacttgcctt acagctctga
     1141 ggagggtgtt tccaggggca gaaactatga tggagaacaa aaaaagaagg aagagggaaa
     1201 gagagagagg cttgaagaag agaaaggaga gaaaaccctg aggaacgagg tggaacagga
     1261 gcgaaccctc cgaggggatg tattctcccc taaggtaaat gaagcagagg atttggatct
     1321 ggtctacgtc caaagaaaag agctaaattc caaactgaag cacaaagact taaacatctc
     1381 agttgactgc agctttgatc ttggggtctg tgattggaaa caggatagag aagatgattt
     1441 tgactggcat cctgctgatc gagacaatga tgttggttac tatatggcag tccctgcact
     1501 ggcagggcac aagaagaata ttggccgatt gaaacttctc cttcccaact tgacacccca
     1561 aagcaacttc tgtttgctct ttgattaccg gctggctggg gacaaagtag gaaaacttcg
     1621 agtgttcgtg aaaaatagca acaatgccct ggcatgggaa gagactaaaa atgaggatgg
     1681 aaggtggagg acaggaaaaa tccagttgta ccaagggatc gatactacca aaagtgtcat
     1741 ttttgaagca gagcgtggca aaggcaaaac tggagagatt gcagtggatg gagtcttgct
     1801 ggtgtcaggc ttgtgtcccg atgacttttt atctgtagaa ggttgactgt cactgtcctc
     1861 ctttgtagct tcatatgtgg cttttaaaat gtcatttctc tagggtatct ttttatatca
     1921 cagcctagga ctcttccatc ttataattac aagctgacag tgtacaatgt tccaacagaa
     1981 atattatcat aacatgcctt ttttgtatca aatgtactaa gacttgccta tatatagtgc
     2041 cactgtgcct tctcatttgt ttctgaattt tccacatttt attacaaaat gtagaaatgc
     2101 tagcccatct ccccctgccc tatacatttg ctcttcctat ataagttggt gaactttcct
     2161 atataacaac atagaataac aacaacagaa aatgataagt acagataaat ggttaattgt
     2221 tggggctggg aaaatggccc agtggttaaa agtattcatt cctctcgagg acccaggatc
     2281 aatttccagc atccacatgg cagctcacaa ccatctggaa ctccagttcc agagaatcca
     2341 atgcccttct ggcctttgtg gaaactttca tatgtatggt atacatgcat acactacact
     2401 acactacact acacacacac acacacacac acacacacac acacacacac acatacacac
     2461 acagagtaaa tcaatttctt aaattgttta actttcacgg tacttcttgg aaacaatgac
     2521 attaaacata gatttgtgcc tttgtggctc agcctgctct ttcatagtca agcttgctca
     2581 tttaattttt ttataatcat atccagtaaa cggccttgtg tcatagtaag ataaaatggt
     2641 atcttactga ctctgtttac ttatgtgtac aattctggaa aataaatttt tttattctat
//
