LOCUS       NM_010112               3571 bp    mRNA    linear   ROD 12-SEP-2023
DEFINITION  Mus musculus embryonal Fyn-associated substrate (Efs), mRNA.
ACCESSION   NM_010112
VERSION     NM_010112.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3571)
  AUTHORS   Wong W, Estep JA, Treptow AM, Rajabli N, Jahncke JN, Ubina T,
            Wright KM and Riccomagno MM.
  TITLE     An adhesion signaling axis involving Dystroglycan, beta1-Integrin,
            and Cas adaptor proteins regulates the establishment of the
            cortical glial scaffold
  JOURNAL   PLoS Biol 21 (8), e3002212 (2023)
   PUBMED   37540708
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3571)
  AUTHORS   Vahedi-Hunter TA, Estep JA, Rosette KA, Rutlin ML, Wright KM and
            Riccomagno MM.
  TITLE     Cas Adaptor Proteins Coordinate Sensory Axon Fasciculation
  JOURNAL   Sci Rep 8 (1), 5996 (2018)
   PUBMED   29662228
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3571)
  AUTHORS   Lee M, Yoon J, Song H, Lee B, Lam DT, Yoon J, Baek K, Clevers H and
            Jeong Y.
  TITLE     Tcf7l2 plays crucial roles in forebrain development through
            regulation of thalamic and habenular neuron identity and
            connectivity
  JOURNAL   Dev Biol 424 (1), 62-76 (2017)
   PUBMED   28219675
REFERENCE   4  (bases 1 to 3571)
  AUTHORS   Gurdziel K, Vogt KR, Walton KD, Schneider GK and Gumucio DL.
  TITLE     Transcriptome of the inner circular smooth muscle of the developing
            mouse intestine: Evidence for regulation of visceral smooth muscle
            genes by the hedgehog target gene, cJun
  JOURNAL   Dev Dyn 245 (5), 614-626 (2016)
   PUBMED   26930384
REFERENCE   5  (bases 1 to 3571)
  AUTHORS   Riccomagno MM, Sun LO, Brady CM, Alexandropoulos K, Seo S, Kurokawa
            M and Kolodkin AL.
  TITLE     Cas adaptor proteins organize the retinal ganglion cell layer
            downstream of integrin signaling
  JOURNAL   Neuron 81 (4), 779-786 (2014)
   PUBMED   24559672
REFERENCE   6  (bases 1 to 3571)
  AUTHORS   Ishino M, Ohba T, Inazawa J, Sasaki H, Ariyama Y and Sasaki T.
  TITLE     Identification of an Efs isoform that lacks the SH3 domain and
            chromosomal mapping of human Efs
  JOURNAL   Oncogene 15 (14), 1741-1745 (1997)
   PUBMED   9349509
REFERENCE   7  (bases 1 to 3571)
  AUTHORS   Yamabhai M and Kay BK.
  TITLE     Examining the specificity of Src homology 3 domain--ligand
            interactions with alkaline phosphatase fusion proteins
  JOURNAL   Anal Biochem 247 (1), 143-151 (1997)
   PUBMED   9126384
REFERENCE   8  (bases 1 to 3571)
  AUTHORS   Alexandropoulos K and Baltimore D.
  TITLE     Coordinate activation of c-Src by SH3- and SH2-binding sites on a
            novel p130Cas-related protein, Sin
  JOURNAL   Genes Dev 10 (11), 1341-1355 (1996)
   PUBMED   8647432
REFERENCE   9  (bases 1 to 3571)
  AUTHORS   Ishino M, Ohba T, Sasaki H and Sasaki T.
  TITLE     Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which
            contains a Src homology 3 domain and associates with Fyn
  JOURNAL   Oncogene 11 (11), 2331-2338 (1995)
   PUBMED   8570184
REFERENCE   10 (bases 1 to 3571)
  AUTHORS   Polte TR and Hanks SK.
  TITLE     Interaction between focal adhesion kinase and Crk-associated
            tyrosine kinase substrate p130Cas
  JOURNAL   Proc Natl Acad Sci U S A 92 (23), 10678-10682 (1995)
   PUBMED   7479864
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT025533.11 and AK030321.1.
            
            [WARNING] On Sep 25, 2023 this sequence was replaced by
            NM_010112.5.
            
            On Dec 9, 2009 this sequence version replaced NM_010112.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK030321.1, BC005438.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-874               CT025533.11        91889-92762
            875-3571            AK030321.1         2-2698
FEATURES             Location/Qualifiers
     source          1..3571
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 27.99 cM"
     gene            1..3571
                     /gene="Efs"
                     /note="embryonal Fyn-associated substrate"
                     /db_xref="GeneID:13644"
                     /db_xref="MGI:MGI:105311"
     exon            1..1351
                     /gene="Efs"
                     /inference="alignment:Splign:2.1.0"
     exon            1352..1630
                     /gene="Efs"
                     /inference="alignment:Splign:2.1.0"
     exon            1631..1771
                     /gene="Efs"
                     /inference="alignment:Splign:2.1.0"
     exon            1772..2491
                     /gene="Efs"
                     /inference="alignment:Splign:2.1.0"
     exon            2492..2581
                     /gene="Efs"
                     /inference="alignment:Splign:2.1.0"
     exon            2582..3571
                     /gene="Efs"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagctccccg gagcgcgcgg accagaccac cccgcggtct gctgcgcggt cccgaggagg
       61 aaggtgcggg ggagagtggc cgggctgggg cgcgcagttt ggcccgaggg tctggagctg
      121 aaactcaaca ccgcctcgga aaggatcgtc ccctttccct acagcttccc cttccccctt
      181 cctccccctt ctcttaatcc cctggcccga gcccctcgcg agaggaatgg gcctgcgggg
      241 aggggaggga gagcttgccg agggggagcg ggagcccggg caagggaggg aaggggcgcg
      301 gagtgcaagg ggtgatcggg ggccgcgcgc gaccccggac cttttctaac cctcagtgtc
      361 cccacctcga ccctaggcga gcccacagca ctgctcctcc ccttctctgt tcccttttgc
      421 tcggtgcctt tttcttcatt tcccaagaca cctggagctt ccctaagctt tgggacgcgc
      481 cgagggcccg gtccagggtg tgtgagcggg gactggggcc agaggggtgc ctggggcaaa
      541 gggtggtgcg cgcccttgag cgctgagact gagaggtgcc tggcggccac ctccaagacc
      601 cggctgtgtt gagaaggagt gtggccggga gagctcgcct cggcgcgggc ctgggcagac
      661 agcccagctc caccgccacg cgctcttagg ccttttggcg ccggcctttg cgctgacttg
      721 agcgagtttg gcgacacgca gctcagttgt cgctcctcct ccttccccgc gggtcccgcc
      781 gcagtggccc ggctgccacg accacagaca gccctgggag caccgctctg cgccgctggg
      841 ggagggttgg ccccaagagt cgctcgtcca gcccaaccac tcaggcggct tctcccagcc
      901 ctcggggcta gcctgagctg cttggagagg cgtcgaaagc agccacagct cctgtctctt
      961 agcctgggaa gtgagctgtg agcccatgtg agtccaggag gcctctgcga cttaaggcgg
     1021 cagctgtggg ggcctggagc cccgagagac cctgggggac aatttagagc gcgccccttg
     1081 gatgaggtcc cgcagcgacg cccaggcccg ccttactcct cctcctgctt ggccaagctg
     1141 cctcctattt ggaaagtttt gtgggttttc tttctcttcc tccaactttg gggggaggca
     1201 tctatctcct caagcgctac agcttggggt gaccttctga cttggaggcc gggaaccatg
     1261 gtgtggggca gccatcgctg aagtcagcga aacagagcct ggcctgaagc aggcgacgct
     1321 ggaggccaga gccatggcca ttgccacgtc ggcccagctt gcccgggcat tgtacgacaa
     1381 cactgcagag tccccccagg aactgtcctt ccgccgaggg gatgttctac gggtactgca
     1441 gagggagggt gctggtggac ttgatggttg gtgcctctgc tctctgcatg gccagcaggg
     1501 tattgtccct gctaacagag tgaagctcct tcctgctggc ccagcaccca agcctagcct
     1561 ctgcccagca tctcccaccc agcctggctc atcatgtccc accccagagc gtggctgtga
     1621 ggagcaggag gtgtatgtaa taccaccacc agctcgaccc tgctctgcct cgggacttcc
     1681 agctagatcc tgctcaccct cttctgactc catctacaag gtcccccgag gcaatgggat
     1741 gcagctgact gcctccagag acgtggcaga ggtctatgat gtgcctccca acatcctccg
     1801 ggctccctcc agctgtccct atgactcccc agcctccttt tcctgtcctg tggccccagt
     1861 tgtcccacag ccccccagag aggatgaagc gccctacgat gtgcctctgg ccttaaagcc
     1921 acctgcagag ctggagcggg atccggagtg ggaagggggc cgggagccag ggcctcctct
     1981 ttacgctgcc ccttccaacc tgaaacgggc ctcggctctg ctcaacctgt acgaagcacc
     2041 cgaggaactc ctggcaaatg gagaaagcag ggatgcagat gaaggcattt acgatgtgcc
     2101 tctgctgggg ccagagccac cgtccccaga gcctccagtg gcttcttcct ccactgacct
     2161 ggacactgtg gcccagcttc cgaccagaag ctccccaccc caacacaggc ccaggctacc
     2221 atccactgag agcctgtccc gccgccctct gcctgccctc cctgtctctg aggctcctgc
     2281 tccttctcca gctccttctc ctgccccagg ccgaaagggc agtatccagg acaggcctct
     2341 accccctccc ccaccctgcc tgcctggtta tgggggcctc aaacccgagg gagatccaga
     2401 gtgcagggag gtagccaatg atccagcagg ccctcacaat gaatatgaag gcatcccaat
     2461 ggccgaggaa tatgactacg tgcatctgaa gggtgtggat acagctcagg gttctagacc
     2521 cctggataaa gctttcccag tggatcctga attgctggag aggggactgg cggaacggaa
     2581 ggaagctctg tccccagagg agccactggt cctgtccact ggagacctcc aacttctgca
     2641 cttctacgca gggcagtgcc agagccatta ctcagctctg caagctgccg tggcagctct
     2701 cgtggccagc acccaggcca accagccacc atgtctcttt gtgccccacg gcaaaagagt
     2761 ggtggtggct gctcaccgcc tggtgtttgt tggagacacc ctaggccggc tggcagcctc
     2821 tgcagctctc agagcacagg tgggggctgc aggcacaatg ctggcccaaa ctctgcgggc
     2881 cactgtgctt gctgtcaagg gggctgcctt aggctaccca tctgacactg cagtccaaga
     2941 gatggcgcga tgcgtggcag agcttgcagg gcaggcccta cgctttacca ccctactcga
     3001 tggtctgctc ccctgagggc ctgttcgtcc agccttcccc tcccctgcct accagagccc
     3061 tgcactccgt gttgaggacg gctagaggtt catctctttc ggtcatttta gccactcacc
     3121 gaggtctctc tttccccata tctactgcct tttgtatgag ccattttgta taaattattt
     3181 atatttaata tttcttgctt tgtccaggca ggcatcaggc catctggggt agggagggac
     3241 tggattctcc tcgttatcct gtgtggaggt cgctggactg ccttctgcct tggggagttt
     3301 ggaacacaga aaatcaggtg gctgaaactt ggtgccacac agagcctctg tcctgtttct
     3361 tggctgaaga tgacaatgta atagtctgag aaacaccaga gagcttctcc cctcacaagt
     3421 caggagagcc ggccacagac aggcatggca tgcacctcaa taaacgctgc cgtatggttc
     3481 ctgactctgc ttcttgaaag cttgagggga cgaggcctgg cacccttccc cattcctgtg
     3541 agacacatac tgtaattttg ctccaaagac c
//
