LOCUS       NM_028889               1866 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus EF hand domain containing 1 (Efhd1), transcript
            variant 1, mRNA.
ACCESSION   NM_028889
VERSION     NM_028889.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1866)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1866)
  AUTHORS   Ebeid,M., Barnas,K., Zhang,H., Yaghmour,A., Noreikaite,G. and
            Bjork,B.C.
  TITLE     PRDM16 expression and function in mammalian cochlear development
  JOURNAL   Dev Dyn 251 (10), 1666-1683 (2022)
   PUBMED   35451126
REFERENCE   3  (bases 1 to 1866)
  AUTHORS   Eberhardt,D.R., Lee,S.H., Yin,X., Balynas,A.M., Rekate,E.C.,
            Kraiss,J.N., Lang,M.J., Walsh,M.A., Streiff,M.E., Corbin,A.C.,
            Li,Y., Funai,K., Sachse,F.B. and Chaudhuri,D.
  TITLE     EFHD1 ablation inhibits cardiac mitoflash activation and protects
            cardiomyocytes from ischemia
  JOURNAL   J Mol Cell Cardiol 167, 1-14 (2022)
   PUBMED   35304170
REFERENCE   4  (bases 1 to 1866)
  AUTHORS   Ulisse,V., Dey,S., Rothbard,D.E., Zeevi,E., Gokhman,I., Dadosh,T.,
            Minis,A. and Yaron,A.
  TITLE     Regulation of axonal morphogenesis by the mitochondrial protein
            Efhd1
  JOURNAL   Life Sci Alliance 3 (7), e202000753 (2020)
   PUBMED   32414840
  REMARK    GeneRIF: Regulation of axonal morphogenesis by the mitochondrial
            protein Efhd1.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1866)
  AUTHORS   Stein,M., Dutting,S., Mougiakakos,D., Bosl,M., Fritsch,K.,
            Reimer,D., Urbanczyk,S., Steinmetz,T., Schuh,W., Bozec,A.,
            Winkler,T.H., Jack,H.M. and Mielenz,D.
  TITLE     A defined metabolic state in pre B cells governs B-cell development
            and is counterbalanced by Swiprosin-2/EFhd1
  JOURNAL   Cell Death Differ 24 (7), 1239-1252 (2017)
   PUBMED   28524857
  REMARK    GeneRIF: coordinated expression of EFhd1 in pro B cells and by the
            pre BCR regulates metabolic changes and pro/pre B-cell development.
REFERENCE   6  (bases 1 to 1866)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1866)
  AUTHORS   Tominaga,M., Kurihara,H., Honda,S., Amakawa,G., Sakai,T. and
            Tomooka,Y.
  TITLE     Molecular characterization of mitocalcin, a novel mitochondrial
            Ca2+-binding protein with EF-hand and coiled-coil domains
  JOURNAL   J Neurochem 96 (1), 292-304 (2006)
   PUBMED   16336229
REFERENCE   8  (bases 1 to 1866)
  AUTHORS   Lin,Q., Donahue,S.L., Moore-Jarrett,T., Cao,S., Osipovich,A.B. and
            Ruley,H.E.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
REFERENCE   9  (bases 1 to 1866)
  AUTHORS   Tominaga,M. and Tomooka,Y.
  TITLE     Novel genes cloned from a neuronal cell line newly established from
            a cerebellum of an adult p53(-/-) mouse
  JOURNAL   Biochem Biophys Res Commun 297 (3), 473-479 (2002)
   PUBMED   12270117
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158961.3.
            
            On Sep 28, 2017 this sequence version replaced NM_028889.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC019531.1, AK016491.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-402               AC158961.3         91334-91735         c
            403-550             AC158961.3         66473-66620         c
            551-685             AC158961.3         58325-58459         c
            686-1866            AC158961.3         45247-46427         c
FEATURES             Location/Qualifiers
     source          1..1866
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 44.15 cM"
     gene            1..1866
                     /gene="Efhd1"
                     /gene_synonym="4931430I01Rik; mitocalcin; PP3051"
                     /note="EF hand domain containing 1"
                     /db_xref="GeneID:98363"
                     /db_xref="MGI:MGI:1921607"
     exon            1..402
                     /gene="Efhd1"
                     /gene_synonym="4931430I01Rik; mitocalcin; PP3051"
                     /inference="alignment:Splign:2.1.0"
     exon            403..550
                     /gene="Efhd1"
                     /gene_synonym="4931430I01Rik; mitocalcin; PP3051"
                     /inference="alignment:Splign:2.1.0"
     exon            551..685
                     /gene="Efhd1"
                     /gene_synonym="4931430I01Rik; mitocalcin; PP3051"
                     /inference="alignment:Splign:2.1.0"
     exon            686..1866
                     /gene="Efhd1"
                     /gene_synonym="4931430I01Rik; mitocalcin; PP3051"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1835..1840
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Efhd1"
                     /gene_synonym="4931430I01Rik; mitocalcin; PP3051"
                     /note="hexamer: AATAAA"
     polyA_site      1864
                     /gene="Efhd1"
                     /gene_synonym="4931430I01Rik; mitocalcin; PP3051"
                     /note="major polyA site"
ORIGIN      
        1 accgagcgtc agaaagccac gagcccgcaa agagcgcaca actctctgtc cccgtaccgg
       61 atcgcgaacc tcagttccat caccacaacc cgccatcatg tccagcgagg agctggcctg
      121 caagctgcag cgccggttga gacttgaggt gcgggcagag accgaccagg gcgaccccca
      181 gcctgcaccc tgcgatgccc cagccgggca cccggagcct gaaccgcctg cccgggcgcc
      241 cacagccagc gcggactccg aactgaacct caagctgagc cgcaggctgg acatccacca
      301 gggtacagcg cggccgggcc gctctaaggt cttcaatccc tacaccgagt tcccggagtt
      361 cagccgccgc ctcctgaagg atctggagaa gatgttcaaa acgtatgatg ctggaaggga
      421 cggctttatt gacctgatgg agctgaaact catgatggag aaactggggg cccctcagac
      481 ccacctgggc ctgaagagca tgatcaagga ggtggatgag gacttcgacg ggaagctcag
      541 cttccgggag ttcctgctca ttttccacaa ggctgctgct ggtgagctgc aggaggacag
      601 tgggttgctg gcactggcca agttttccga gattgatgtc gccctggaag gtgtcagagg
      661 tgccaagaac ttcttcgaag ccaaggccca ggccttgtca tgttccagta agttcgaagc
      721 tgagttaaaa gctgagcaag aagagcggaa acgggaggag gaggcccgga ggctccgcca
      781 ggcagccttc cgggagctca aggcagcttt cagcgcgtag tcctgctgac ctgacctttg
      841 accgcggctg tgccttacta acaccctgga ggtgatgacc aggatttttc acatttttat
      901 ccctgcagcc ctctgctcag atgacctccc cttcacggcc caggcctgtt tcttagtgct
      961 tctggataac cagtaacttg ctttcgtcct tcccagggtc ctggtccctt ccaaacggtt
     1021 tgccagccag cctttccagc cttcacccct ctgctgttat ctgtagattc gtttcttctt
     1081 ggaaacctta tttatccctg cggagtccta tgtcaactcc tgttcatcta cggttctcag
     1141 aggacatgtt gcctgtcggc cccgggtagt ttttcctttg tgttccttgt attgtttcct
     1201 ggtcagcgtc tgtctgcctt cttgttatta cccagattcc attgacttct ttttcaccgt
     1261 cttccacgct agtgtgatga tgggatttga aggagcactt gtggatcaat accaatatcc
     1321 cctcaccaac cagggactag tttgatgcta tctttgcctg tctcttggct cttaacaatg
     1381 cctaccctct tgttccccct cgttcatttc ccagtccagc cattttccca ctcctaagtt
     1441 ctttactgtt aagaatgaga gaatcgtcag aagtaatatt agtgagtaga aggatagctg
     1501 tcacccgacc ccattcaaat cagagtggac ctgtgaaact ctcaagtgac atccaaggtc
     1561 ttttgaaatc atgaccaaat tcccgtgtct gacaacagtt ccagagaact gaaagaaatg
     1621 tattctcgcc catgagacag atttttgtat cttgagtttc ttgggacttc tcacaaatac
     1681 ctggggaggg gggttatgta ttttttaaca aaaccaaaac caaaaattct taatgtcata
     1741 tttatttgac ttgtaacttg taactctttt gtaactgctg tctttacaat aaagaaaaca
     1801 tctgcccttc tatcttaaca gctgtttact tttaaataaa acatgcaaat gatctttgcc
     1861 ttcata
//
