LOCUS       NM_145549               2176 bp    mRNA    linear   ROD 26-NOV-2024
DEFINITION  Mus musculus EF-hand calcium binding domain 7 (Efcab7), mRNA.
ACCESSION   NM_145549 XM_355566
VERSION     NM_145549.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2176)
  AUTHORS   Fish,E.W., Boschen,K.E. and Parnell,S.E.
  TITLE     Efcab7 deletion sensitizes mice to the teratogenic effects of
            gastrulation-stage alcohol exposure
  JOURNAL   Reprod Toxicol 130, 108729 (2024)
   PUBMED   39366525
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2176)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2176)
  AUTHORS   Boschen,K.E., Ptacek,T.S., Berginski,M.E., Simon,J.M. and
            Parnell,S.E.
  TITLE     Transcriptomic analyses of gastrulation-stage mouse embryos with
            differential susceptibility to alcohol
  JOURNAL   Dis Model Mech 14 (6) (2021)
   PUBMED   34137816
REFERENCE   4  (bases 1 to 2176)
  AUTHORS   Pusapati,G.V., Hughes,C.E., Dorn,K.V., Zhang,D., Sugianto,P.,
            Aravind,L. and Rohatgi,R.
  TITLE     EFCAB7 and IQCE regulate hedgehog signaling by tethering the
            EVC-EVC2 complex to the base of primary cilia
  JOURNAL   Dev Cell 28 (5), 483-496 (2014)
   PUBMED   24582806
REFERENCE   5  (bases 1 to 2176)
  AUTHORS   Cui,C.Y., Kunisada,M., Esibizione,D., Grivennikov,S.I., Piao,Y.,
            Nedospasov,S.A. and Schlessinger,D.
  TITLE     Lymphotoxin-beta regulates periderm differentiation during
            embryonic skin development
  JOURNAL   Hum Mol Genet 16 (21), 2583-2590 (2007)
   PUBMED   17673451
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX324127.8, MF597759.1, CU326395.5 and CR536609.3.
            
            On Apr 17, 2020 this sequence version replaced NM_145549.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC020077.1, SRR7345562.3015564.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               BX324127.8         21165-21274
            111-298             BX324127.8         23113-23300
            299-510             MF597759.1         4975-5186
            511-597             MF597759.1         6127-6213
            598-793             MF597759.1         8768-8963
            794-912             MF597759.1         9387-9505
            913-1054            MF597759.1         19535-19676
            1055-1164           CU326395.5         6887-6996
            1165-1322           CU326395.5         10022-10179
            1323-1456           CU326395.5         11129-11262
            1457-1605           CU326395.5         14171-14319
            1606-1815           CU326395.5         19065-19274
            1816-1923           CR536609.3         2644-2751
            1924-2176           CR536609.3         4256-4508
FEATURES             Location/Qualifiers
     source          1..2176
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 45.71 cM"
     gene            1..2176
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /note="EF-hand calcium binding domain 7"
                     /db_xref="GeneID:230500"
                     /db_xref="MGI:MGI:2385199"
     exon            1..110
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            111..298
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            299..510
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            511..597
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            598..793
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            794..912
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1054
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1164
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1322
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            1323..1456
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            1457..1605
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            1606..1815
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            1816..1923
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     exon            1924..2176
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2153..2158
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /note="hexamer: AATACA"
     polyA_site      2176
                     /gene="Efcab7"
                     /gene_synonym="mKIAA1799"
                     /note="major polyA site"
ORIGIN      
        1 agttgctatg gtaatctaaa aaaggcggag gtctgtccgg ttgcgccgag aggttcgcgg
       61 atctactaac gaaaattggc tgctcttctt ggtttgtgag ctgaaattag aatggccagc
      121 aaccctggaa gtgatgcagc tttgggtact cagaacccac tgctttctgg gagtcctcga
      181 acaaagaaat tcccactaac tgaacaggag gtgttttata tgaactgtag agccgcctac
      241 ttaactatct tcaaaagcag cttggaaaac attatttcta aagatcaact ttacctagct
      301 cttcagcatg caggaagaaa tccatcccaa aagaccatta ataagtattg gactcctcaa
      361 actgccaaac taaattttga tgatttttgt ataattttaa gcaaggaaaa gcctacttca
      421 aaagcagaat tgctaaaatc atttaaaaaa ttagatgtaa atgatgatgg tgctattcta
      481 cactctgacc ttcagaaata tctaacaaag agaggtgaga agatgactca ggaagaagtg
      541 aatgctgtca taaatttggc tgatataaat gctaatggaa agtttgacta cgttaagttt
      601 tgtaaattat acatgacaac cagtgagcag tgtctcaaga ctacactaga aagactggag
      661 gccgacagta aactgaggcg tcaacagttt ggaagccaca tggaagggtc ccctgaaagg
      721 ggtccgtcac cagcaccaaa accgtcacct agggtcataa gaaaaaatga ccaagaaaca
      781 ttctcaagca aaggtgacac aagccatgcc ttactgtcaa caactagaaa gttcaaaaca
      841 tctgtctcct tcacaatgac catgagcgct aacagtaacc aagactcaac attaactgag
      901 ccaaacttaa aggattggca gtgtgcacag tcaaaaggct gcttcttttt agaagaagac
      961 ggtgaagttg tcagtcatca gtacaaaatg cacatagctc agagatctgt gctttaccta
     1021 acaattaagc cgttatatct gagtcaagtg gaaggaaaac gttgcccctg gttatcggtt
     1081 gacacagcct tatatattct taagaaaaat gagaatccag cagagccaca gctcatgtgc
     1141 tttactgaac tacgaaacag agaagtgttt ggatggactg gtgaactaga agcaggaatt
     1201 tattggttaa ttccttccac aactggctgt aggctaaaaa aagaaacaaa accagtaaca
     1261 gaagaagccc agcttgtaca tagagatgaa acaggggaat tatctcttac aagtgagttt
     1321 aggtcaactt tatcagagat atttgaagta attgatttag atggcaatgg tctgattagc
     1381 cttgaagagt acaatttttt cgaattgaga acaagtggtg agaagtgtga tgaggatgcc
     1441 tgggctgtct gcagagaaaa ctttgacaca aagaagaatg aattaacaag acagggcttt
     1501 atggacttgc atctgatgga agcaaatgac cgagaaggag accctcttga cctgtgggtg
     1561 actctgcatt ccatgggcta taataaggct ctggagctga cagaggcatg cccatttgtc
     1621 atcaacatct acgctgaaag atgcaagcca agaatcaaag ttgtccatat ggaggcatgc
     1681 agtgggcaac ttgaaaaggc catttgcaaa tctgtccttg atagaagcga tgctaaagtc
     1741 atggatggct atgaaaatat aatcgtacat acttgcaatt atgacacatg gataacatca
     1801 attattgaaa ataagtcaga taataaagtg attattcaca tcaataacga actgagtaaa
     1861 aactgtgtca acaacagagg actcaacatc tttgcagtag aagtggcacc aagatctaca
     1921 atggtgtgtc aacatgtaat gcccctgaat gaacaagaag aatggatata ttgttgtgtg
     1981 tattctcttg tagcttaaat aattccattt ggagctatca aactaagaag tattttagat
     2041 cgactatttt atttattaac tacatacttt tccatgtaac tggtgtactt aataatctgt
     2101 ttcatttcta tgcatttata ttttatgtca gtgttttata ttttattatt aaaatacaaa
     2161 tagtgtttta aaagta
//
