LOCUS       NM_001368627            5724 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus EF-hand calcium binding domain 14 (Efcab14),
            transcript variant 2, mRNA.
ACCESSION   NM_001368627
VERSION     NM_001368627.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5724)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5724)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 5724)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK028618.1 and AL626806.14.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK030011.1, AK028618.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2682              AK028618.1         10-2691
            2683-5724           AL626806.14        58573-61614         c
FEATURES             Location/Qualifiers
     source          1..5724
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 53.06 cM"
     gene            1..5724
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /note="EF-hand calcium binding domain 14"
                     /db_xref="GeneID:230648"
                     /db_xref="MGI:MGI:2442397"
     exon            1..1071
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             890..2344
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /note="isoform 2 is encoded by transcript variant 2;
                     EF-hand calcium-binding domain-containing protein 14"
                     /codon_start=1
                     /product="EF-hand calcium-binding domain-containing
                     protein 14 isoform 2"
                     /protein_id="NP_001355556.1"
                     /db_xref="CCDS:CCDS89810.1"
                     /db_xref="GeneID:230648"
                     /db_xref="MGI:MGI:2442397"
                     /translation="MKKRKELNALIGLAGDHRRKKTKQGSGSHRLLRTEPPDSDSESS
                     TDEEEFGAIGNRSRFVKGDYARCCKICCPLCAFVILAACVVASVGLVWMQMALKEDLD
                     VLKEKFRTMESNQKSSFQEIPKLNEELLSKQKQLEKIESGELGLSRVWINITEMNKQI
                     SLLSSAVNHLKASVKSAADLLSLPSTVEGLQKSVASIGNTLNSVHLAVEVIQKTVDEH
                     RTTLGLLQGSMENNGSNQILPSPSPPSELDNKSHSESAKQDILYLHNSLEEVNSTVVE
                     YQRQNDLKLKGMSETLSNLTQRLSLIESHVVALSKAEQRTNVSSSTMENRAATLKRES
                     LVTNRSDTVQAQSMKKEDNSNSQVSELREKLQLISALTNKPESNRPPETTDEEQVQNF
                     TSDPSALPEFSQLLRNQIETQVKPLSLPGISSIKDLQDLFHKTGQDVDGMLTYQELWN
                     SLGSAMPRPESLRAFDSNGDGRYSFLELRLALGI"
     exon            1072..1220
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1366
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..1465
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..1576
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1663
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1664..1855
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1856..1936
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1937..2048
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2049..2168
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2169..5724
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5636..5641
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5658
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /note="major polyA site"
     regulatory      5695..5700
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      5724
                     /gene="Efcab14"
                     /gene_synonym="4732418C07Rik"
ORIGIN      
        1 aagtgagcta agactggagc tatggcccgg gtctggagcc tgcggcggcc gccaccgcca
       61 gcacatccag agaagtcgcg accgaagcag gggccggaga cgcggctgga ctggccgcgg
      121 cgcgtgtgag ttgcggaagt cgctggtggc ggaacacttc aggctggcgg agcggtggtc
      181 acccctcatc actgcgcccc ctccaggccc tagcagcagg gctcccgctc ctctcgcgcg
      241 ggtctctaca aactcaggac agaagccacg ggaaggtgat catcccgaat cctggtgggc
      301 gtcccggcct gggagttttc taggcgccca ggcagtgttg gcgctctcct gtcaccacct
      361 ctccagttaa ggatcagcga gttcccactg cctgctctgc aaagtctcct ctcctcccat
      421 tcaaaaacaa gtttattttc cttctgcatt gggaatcttg tcccagagat ctaaagtacc
      481 ttagttttgt gtatctttct cccgctttct ggagcactcc tagaaatatt ggttgcctac
      541 acgacttaga atctcgtgct tgacttagcg ggttgttttg tttcgttttc cttttgacag
      601 gtaatagttg tttcagaaat ttatccattt agatctccag ttccttggcc atctctatgt
      661 aacttccccc accccccatc ccccatccac ctgagtccaa ttttctctgg gctctattct
      721 ccagccctca gtagatctgg tcagtcccac ctctgggtgg gagtgatcag ggggctcagg
      781 cccaggattt ccaaccctgg aaggcagctc caagtcagcg agagagttgg gtgttggcta
      841 cgaacctggc agctcaggag tgggcccgcc actcaccccc cacaaaaaga tgaaaaagcg
      901 caaagagctc aatgcgttga tcggcctggc tggtgaccat cggagaaaga agaccaagca
      961 aggctcaggc agccaccgcc tgcttcgcac tgagcctcct gactcagact cagagtccag
     1021 cacagacgaa gaggaatttg gagcaattgg aaatcgctct cgttttgtca agggagacta
     1081 tgcccgatgc tgcaagatct gctgtcccct ctgtgccttt gtcatcctcg cagcctgcgt
     1141 tgtggcctct gtgggcttgg tgtggatgca aatggctctc aaggaggatc tggatgtcct
     1201 caaggaaaaa tttagaacaa tggagtctaa tcagaagagc tcattccagg aaatccccaa
     1261 acttaatgag gaacttctca gcaaacaaaa acaacttgag aagattgagt ctggggagct
     1321 gggcttaagc agagtctgga tcaacatcac agaaatgaat aagcagattt ctctcttgag
     1381 ttctgcagta aaccacctaa aagccagcgt caagtcagcc gcagacttac ttagtctgcc
     1441 tagcactgta gaaggacttc agaagagtgt ggcttccatt ggcaatactt taaacagtgt
     1501 ccaccttgct gtagaggtga tacagaagac tgtggatgag cacaggacaa ccttggggtt
     1561 actgcagggc agtatggaga acaatggaag caaccagatc ttgccatcac cttcacctcc
     1621 atcagagctt gacaataaat cccacagtga aagtgcaaaa caggatatcc tgtacctgca
     1681 caactcctta gaggaagtca acagtactgt agtggaatac cagagacaga atgaccttaa
     1741 actcaaggga atgagcgaga ccctcagtaa cctgacacag agactcagcc tgatagaaag
     1801 ccatgtggtt gcactgagca aggcagaaca gagaacaaac gtgagctcca gcacgatgga
     1861 gaatagggct gccactctga aaagagagtc tttggtgacc aacagaagtg acactgtaca
     1921 ggcgcaaagc atgaagaaag aagataattc aaattctcag gtatccgagc ttcgagaaaa
     1981 actgcagctg atcagtgctc tcacaaacaa acctgaaagc aacaggcctc cggagaccac
     2041 agatgaagag caagtacaga acttcacatc agatccttca gcattgccag aattttcaca
     2101 gcttcttaga aaccaaattg agacccaagt aaaacctctc tccctgcctg ggatttctag
     2161 catcaaagat cttcaggatt tattccacaa gactggtcaa gatgtggatg ggatgctgac
     2221 ctaccaggaa ctctggaact ccctaggttc tgccatgcca agaccagaga gcttgagagc
     2281 atttgattcg aatggagatg gaagatactc tttcctggaa ctaagattag ctttaggtat
     2341 ctagtctcat caggtatatt tgaaacggat atgtagcctg gactacctaa aaatctactt
     2401 aactaaaaag acagaaaaaa acaaaaacaa aaaccttctt gactaactct tcagccctcc
     2461 agtcctttat actactataa caaacacatt gtcacctttt aacttgtttg aaaacactat
     2521 ttaaaaaatt atttttttaa aaaaatttac ttaaagtatg atgtttagaa atctatgatt
     2581 tcatgaagcc agtgagatgt tgtaacttaa agttgccagg aaaaaaaaat aaagccctct
     2641 tctctctttc ctgttttttg aggggaagag aatttacctt ttaaagctgg aaagtgtatg
     2701 tatatagaga taataagtca gtttatattt catatgaatt tgccttaaat tagatgcact
     2761 ttatagagcc tcagaatatg tcttttcttt gaaagatgag tctcttctgt ttgtaaatat
     2821 ataagatgaa agattgtgca taatgtgtag aaagacgatt ggctttgaat ggaatgaatg
     2881 aatgacttgt tatgagtaac tgacagtctg ctctgggtgg caactgaacc tcttcacacc
     2941 tccttaaggc agccctcaaa tgcttgggca ccaccatagg gtttgaagct ggggcatcag
     3001 ttcaggtatg gatgctgtgc agagggtgcc agttccaaac tcaggaaagt cagattctgg
     3061 gccactgctc ctattcctaa cctaagaacc agagaagtct tactgggatt ttcctcattt
     3121 ttaattatct ttcaaggatt atgagcgtaa aagttactcg gtgggaaatt atatgttttc
     3181 ccctcaagaa gtgggtcttc tctgcccacc cactctagac taccttaaag ttgtaactgc
     3241 ctaccttcag caccatgtcc agtcagaaat gggaaggttc atgtccttgg ctgctatccc
     3301 aaactagttg cccagagcac tagagaaaag ctctgagtac cctttgattt tacctttagg
     3361 ataaccaaga atttgctcta tttcttggca ggatgcctaa agccaaaatg tggtctgatg
     3421 aaacaggaaa tcatattctt tcttcctaat tgttcactca aaaggagcta tgggttttct
     3481 gtccagagga taccacatgg agcaggcgtg cttggagcag gagccttctg gtgatggggc
     3541 tgttttccca ggtctaaaga gcatctgtga tgcttccgct tacatgcttt gtgggcaggc
     3601 caggacaggt ctgataggag cagatcacca ttcgctgaca tgttgagaca ctcccagtgc
     3661 tcttaggcgt ctctggcagc tccagcagaa gaccttacag aaccgcaggt tgctgtagcc
     3721 gtcagggaaa cactggagaa gctgttgtga tggcagggct tctttactaa agatcattgc
     3781 tgtttaattt cgatcaagtt gccctgtcag ctatagatac agtctagtac ctttaacctt
     3841 taaagacatt tggttttcgc tttgctttgc cttgcttttt atattttgtt tcttttatat
     3901 atgatattca gcttagtgtt ggcttttttt ttctctagac attaaaactc agtgaaggca
     3961 agacaagttt tcctgtgcat gagtcttctt agctcatgtt tctctctctt taaatttttt
     4021 gccttaatgt ttgccttgct catctatgct gtcaccttct tggaaaggtt aaaaatacag
     4081 ttcaaacatt atcctggctc tttaggtaac tcttgttctc ctggctgcct tccatactaa
     4141 acacacacac acacacacac acacacacac acacatccgt acagattttg taacaaccaa
     4201 ataaagttct agcaataaat tgaattattc tgctatattt gtatatattg taccataaat
     4261 agtatgtctg tacctggaag gtttttcttt ttttctttct ttctttcttt cttttttttt
     4321 ttttttttga gaactgattt atatgaaata tactgagggt aatgtagctt gtccttttta
     4381 gtttcaagtt ctcatttgta ggcagatact ttcaagacac cttaactctt tgtggtatat
     4441 gcttttcagt gaggaagcag gatttgtttc ttggactttc ttctggtttt tccatgtcaa
     4501 gaagcttgtc tgccagcatc acccctgagc catgtgatgt ctcttatcaa actgaccaga
     4561 ggtagccata actgccctct gacattctat acgtttctca tcctgactat ggcattacca
     4621 gatctaggca gaggttgcta tcctttgcta gaaattggac agactcactg gcttaggagc
     4681 cccaaaaacc tatcaatcgg tgaagattgg gtcttcattt gtttattgtc ttaccttgtg
     4741 catccagtgc cttgtgttag tcaagcttca ccagccacag atcacctcta agagaactca
     4801 atggtagtgg tggtgagttt ggctttggat ttcaatcctt tggccttatc agtcagtagc
     4861 taagagtact tcccacctta gtttcttaaa gtgttaccct tggtcctttg ctttatgtac
     4921 catctaccat aatatttact gaaagaccat tcacaagcca gtcatggtag tacatacctg
     4981 taatcccagc ccttgggaga ctgagacagg aaagtaatga gttctagtcc agtctgggct
     5041 ccatagtgag atcttgtctc agaaaagtac ctggcttaaa tatgactgta gtaacattca
     5101 aggaggagca gagcaatgga tgcttggctc ttaagaatgg gtctaatgca gaagagctga
     5161 ggcagacagt ctcacttcac gaccagcttg tttcccttcc attgcagttt gctctttacc
     5221 attgctggac agccccatca gccccctccc tggtcccagc gtcacagctg aaggttttga
     5281 ctgtgatggg ctcacactta taatggccta ttgagttgtt tttagtgaca gcttttgttt
     5341 gctacacacc tcattggctt gcttaccaac catctagatg tggtcccttc tctcatattc
     5401 aagccagaac acatttgggt attcctgaga ctagagagtg tgtattgttt gttatataaa
     5461 cctaacctac cttgttgttt tctcatatta agaacggtaa atctacttta tattaatgga
     5521 actattttgg taatacataa gcaattttgg ttttgtttag agtggattca aggtttccat
     5581 gacttcattt gagctttact tacttcctat caatatagcc attttaattt atctaaataa
     5641 aacattacgt ttctctcact gtgtctgact agaattttcc ctgctcccct gataattaaa
     5701 gggggaaacc tgctttaatc ttta
//
