LOCUS       NM_030172               2069 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus EF-hand calcium binding domain 11 (Efcab11), mRNA.
ACCESSION   NM_030172 XM_354690
VERSION     NM_030172.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2069)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2069)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 2069)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC160931.2 and
            AC155266.2.
            
            [WARNING] On Feb 21, 2025 this sequence was replaced by
            NM_030172.3.
            
            On Nov 17, 2006 this sequence version replaced NM_030172.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011507.1, BC049109.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-161               AC160931.2         55767-55927
            162-257             AC160931.2         56352-56447
            258-303             AC160931.2         60807-60852
            304-405             AC160931.2         83570-83671
            406-496             AC160931.2         84509-84599
            497-2069            AC155266.2         79969-81541
FEATURES             Location/Qualifiers
     source          1..2069
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 50.25 cM"
     gene            1..2069
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /note="EF-hand calcium binding domain 11"
                     /db_xref="GeneID:78767"
                     /db_xref="MGI:MGI:1926017"
     exon            1..161
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..575
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /note="EF-hand domain-containing protein C14orf143
                     homolog"
                     /codon_start=1
                     /product="EF-hand calcium-binding domain-containing
                     protein 11"
                     /protein_id="NP_084448.1"
                     /db_xref="CCDS:CCDS26104.1"
                     /db_xref="GeneID:78767"
                     /db_xref="MGI:MGI:1926017"
                     /translation="MFLSEAGARPRAGEASASERRKWVKVFKACDEDNKGYLSREDFK
                     VAIVMLFGYKPSKIEADAVMSSVNPNTSGVSLEGFLSAVKRKKEARLYRNEIRQIFTA
                     FDVHYRGFLTLEDFKRAFSRVAPKLPARTVLEVFREADQDSDGHVSFRDFEYAMNHGQ
                     SK"
     exon            162..257
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            258..303
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            304..405
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            406..496
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            497..2069
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      677..682
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /note="hexamer: AGTAAA"
     polyA_site      694
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /note="major polyA site"
     regulatory      1490..1495
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1515
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
     regulatory      1828..1833
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1860
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
     regulatory      2041..2046
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2068
                     /gene="Efcab11"
                     /gene_synonym="2610021K21Rik; 2610110A13Rik"
                     /note="major polyA site"
ORIGIN      
        1 agcggtggtg ggcgaggccg cagtggctgg tctgtgttct cgctgcagcg gaggagacgc
       61 ctggcttggt ctccgtgtcg gtggcgatgt tcttgtcaga ggcaggcgca aggccccgag
      121 caggcgaagc cagcgcctca gaacgcagga aatgggtgaa agtatttaaa gcatgcgatg
      181 aagacaacaa aggctaccta agccgagagg actttaaggt tgcgattgta atgctgtttg
      241 ggtacaaacc ctccaagata gaagcggatg ctgtgatgtc ttcagtaaat cccaacactt
      301 ctggtgtttc acttgagggg tttttgagtg ccgtaaagag aaagaaggaa gcgcgactct
      361 atcggaatga gataaggcag atcttcacag ctttcgacgt gcactatcgt ggatttttaa
      421 ctctagaaga tttcaagagg gcgtttagtc gagtggctcc caagctacca gcgaggacag
      481 tgctggaggt gttcagggag gcagatcaag actcagatgg tcacgtcagc ttccgagact
      541 ttgaatacgc catgaaccat gggcagtcaa aatgagccgg gtgcttgtga actacttgga
      601 cagctcgatg gattgtaatc tagttgaagg tctcacagac ctcaatctag gaagggtatg
      661 aaactgtgta cttgtgagta aactcttagt tagagctttt gaatgctgat attggaccta
      721 gagatgggaa tctcctgtgt gtgtctccag cagccctgag tcaggctgct actgctggcc
      781 ctgccaccca gtgggtttgg agtttttccc cctctctgct cttgtcagct ttctgtcctc
      841 tatcctgtgg gttggaggct ctgctaactc cgcatgagtc cctcactctt gtcagctccg
      901 ggaaaagtta cctttgctct gctagcagtg tcattgccat tcacttgctc cacctcggct
      961 gaacatcaag cttactgtgt ccaagcaatg agctagtgct aggaaaacaa agactctgag
     1021 atgatgcgcc tggggtacag agaggtgcac agggcacctg tgtacaaagc ctaggaggaa
     1081 gcagctctgg ctaggccatc agccattctt tatacagaga agtccaggat gtaactgggg
     1141 tcttaatggg cagaagggtg tggtctttgg ttccctttag gatagcctgg acctgagcct
     1201 gggcttcttt cttcagagaa gctagctaga gaagctggcc ggcagccctc tgccacacac
     1261 ttctggttct aggtagttct gccctggacc tgaagctcca gccatcctag agttaggagt
     1321 ctccactccc tgccatgccc ctgggcgcca gtgatcacat caagtcacaa catacagctc
     1381 agcatctact aaagataact ctgaaatacc aacattgtcc ttgtaagtgt ttcacaacat
     1441 taacatttgt ggtataatta atgcaattta tgtttttaaa gtgttaaaca ttaaacgatc
     1501 aagtagaaat ataaatttgt atagccaaca ttcaacaagc ttcatgctca tataaattat
     1561 tagtagatag ccttaagaaa aataaagttt ttagctatgc taaaccagag gaacctaaga
     1621 gatgggataa ctaaatgtaa tttgactgaa atgtaatttg gtctcctaac gggcccctag
     1681 ggaccatacg gtagagatga accaagcctg gacttcctct gctacttgtg atagtgtggg
     1741 agactgggtg atggatagat aggatttcta ctgttttcat gatttttcta taaatctaaa
     1801 attatcctca aacggagttt gttaaaaatt aaaggcttag tcaaacattc ataaactaaa
     1861 tgaagaagca atgaaaataa tttctcaaca tgaatgaaat attatttcag aggcagaaat
     1921 gaattactgg tatcattgag aagtgtgtat gactttgtgc acagtagtcc agtttctgac
     1981 tttgttcagc aagtgttttc attataagac aaaccaaatc attgatcctg atctcaaaat
     2041 attaaagaga tatttttgat ttcttaaat
//
