LOCUS       NM_153560               4245 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus estrogen-induced osteoclastogenesis regulator 1
            (Eeig1), mRNA.
ACCESSION   NM_153560
VERSION     NM_153560.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4245)
  AUTHORS   Yamashita,Y., Hayashi,M., Liu,A., Sasaki,F., Tsuchiya,Y.,
            Takayanagi,H., Saito,M. and Nakashima,T.
  TITLE     Fam102a translocates Runx2 and Rbpjl to facilitate Osterix
            expression and bone formation
  JOURNAL   Nat Commun 16 (1), 9 (2025)
   PUBMED   39747056
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4245)
  AUTHORS   Jeong,E., Kim,J., Go,M. and Lee,S.Y.
  TITLE     Early estrogen-induced gene 1 facilitates osteoclast formation
            through the inhibition of interferon regulatory factor 8 expression
  JOURNAL   FASEB J 34 (9), 12894-12906 (2020)
   PUBMED   32741026
  REMARK    GeneRIF: Early estrogen-induced gene 1 facilitates osteoclast
            formation through the inhibition of interferon regulatory factor 8
            expression.
REFERENCE   3  (bases 1 to 4245)
  AUTHORS   Choi,H.K., Kang,H.R., Jung,E., Kim,T.E., Lin,J.J. and Lee,S.Y.
  TITLE     Early estrogen-induced gene 1, a novel RANK signaling component, is
            essential for osteoclastogenesis
  JOURNAL   Cell Res 23 (4), 524-536 (2013)
   PUBMED   23478294
REFERENCE   4  (bases 1 to 4245)
  AUTHORS   Torres-Padilla,M.E. and Zernicka-Goetz,M.
  TITLE     Role of TIF1alpha as a modulator of embryonic transcription in the
            mouse zygote
  JOURNAL   J Cell Biol 174 (3), 329-338 (2006)
   PUBMED   16880268
REFERENCE   5  (bases 1 to 4245)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Kitamura,H., Nakagawa,T., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
REFERENCE   6  (bases 1 to 4245)
  AUTHORS   Torelli,D., Rovati,C., Lo Dico,C. and Frizzi,R.
  TITLE     [Indications for kidney transplantation in the treatment of
            advanced chronic renal insufficiency]
  JOURNAL   Minerva Chir 34 (21), 1443-1447 (1979)
   PUBMED   399665
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928710.6.
            
            On Jan 12, 2022 this sequence version replaced NM_153560.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC023752.1, AK170536.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-901               AL928710.6         128942-129842
            902-1022            AL928710.6         151637-151757
            1023-1052           AL928710.6         151928-151957
            1053-1169           AL928710.6         153649-153765
            1170-1216           AL928710.6         157029-157075
            1217-1374           AL928710.6         157212-157369
            1375-1479           AL928710.6         159011-159115
            1480-1696           AL928710.6         159198-159414
            1697-1818           AL928710.6         159879-160000
            1819-1888           AL928710.6         160098-160167
            1889-4245           AL928710.6         161005-163361
FEATURES             Location/Qualifiers
     source          1..4245
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 22.09 cM"
     gene            1..4245
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /note="estrogen-induced osteoclastogenesis regulator 1"
                     /db_xref="GeneID:98952"
                     /db_xref="MGI:MGI:2138935"
     exon            1..901
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /inference="alignment:Splign:2.1.0"
     exon            902..1022
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1052
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1169
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /inference="alignment:Splign:2.1.0"
     exon            1170..1216
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1374
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /inference="alignment:Splign:2.1.0"
     exon            1375..1479
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /inference="alignment:Splign:2.1.0"
     exon            1480..1696
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1818
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /inference="alignment:Splign:2.1.0"
     exon            1819..1888
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /inference="alignment:Splign:2.1.0"
     exon            1889..4245
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4223..4228
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /note="hexamer: ATTAAA"
     polyA_site      4245
                     /gene="Eeig1"
                     /gene_synonym="C230093N12Rik; Fam102a"
                     /note="major polyA site"
ORIGIN      
        1 attctccgag cagcgccgag ctgcgtcggg ctcagccggc tgcgtccgga ggtgcgggcg
       61 acggcgccgc tgtgctccag cggtgctaac cgaggcagaa gccatccggc cgggtcggaa
      121 ggcgcctgag actcgggcag ggcaggagcg gcgtaggtcc caggactgag cgggaggcgg
      181 accggcacac gttcccggcc cggcagagcc tcccgaagcg gtccctgcag agccgggtcg
      241 gtcgccgagg tggcttccgc ttcccggggc ctcacctgcg caggccgcgg tgcgccaggt
      301 gcggaggcgt gtgcgtcgcc tgggcacctc ccacggcagc cagcggggcg gaggcggggc
      361 cgccgcccgg gtctccagcg gttcgcccgg ccgtctccgt cagtctcacc ggtccgccgg
      421 gccccgcgga tcgggatgct gctgctcgct tgcgagccgc cctccacgcc agcccccgct
      481 gccggggccg cacctcgctg tttacatgtc agtggagccc gggttccccg agggtgagag
      541 cagccggctc actggacctg gggctccgaa ctcagatcct ctcctgcccg cagcctccgc
      601 cgccatctgg actggatcca gctctggtgt ttttgaggag gggggtgtgg tgtcgggaaa
      661 ggaatcctgg ggttttctag tatccccttc tttttttctt ttttcttttc tttttctttt
      721 tggccctgcg ggcttcagac tcagggaact tgctcatggc ttttttgatg aagaagaaga
      781 aatttaaatt tcaaaccact ttcaccttgg aggagctgac tgcggtcccc ttcgtgaacg
      841 gggtcctctt ttgcaaggtc cggctgctgg atggcgggga ttttgtcagc ttgtcgtcca
      901 gggaggaggt gcaggagaac tgtgtacgat ggcggaagag gttcaccttt gtgtgtaaaa
      961 tgagtgccaa cccggccaca ggcctgctgg acccctgcat ctttcgagtg tctgtgcgca
     1021 aggagctgaa aggtgggaag gcgtattcca agctgggctt cactgacttg aacctagccg
     1081 agtttgcagg ctcaggctcc accgtccgct gctgcctatt ggaaggatac gacaccaaga
     1141 atacccgcca ggacaactcc atcctcaagg tcaccattgg catgttcctg ctctctgggg
     1201 acccctgttt caagacgcca ccgtctaccg ccaaatccat ctccatcccg ggccaggact
     1261 cctccctgca gctgacgtgt aaaggtggtg ggaccagcag cggtggcagc agcagcacca
     1321 attccctaac tggatcccgg ccccccaaga cccggcccac catcctgggc tcaggactac
     1381 cagaggagcc agaccagagc ctgtccagtc ctgaggaggt gttccactct ggccactccc
     1441 gcaactccag ctatgccagc cagcagtcca agctatctgg ctacagtaca gagcactctc
     1501 gctcctccag cctgtctgac ttgacacacc gcagaaatac atccaccagc agcagcgcct
     1561 ctggtggcct cagtatggct gtagagggtc ctgagggcat ggagagggag catcggccct
     1621 ctgagaagcc acctcggcct cctgagaagc ccccacgccc cccacgcccc ttgcatctat
     1681 cagatcgctc ttttcggcga aagaaagact ctgtggagag ccacccaacc tgggtagatg
     1741 acactcgaat tgatgcagac gacattgtgg agaagataat gcagagccag gacttcactg
     1801 atggcagcaa cactgaggac agtaaccttc ggctgttcgt gagccgtgat ggctccacca
     1861 cactgagcgg cattcagctg ggcaacagag tctcctcggg agtctacgag ccagtcgtaa
     1921 ttgagagcca ctgagggacc caggagtccg gctgaagaag ggtcctgcca tctctggcac
     1981 ccaggcccgt ggcattcctg gaggatctgc tctgcattgc atctgtgcct cctcttactc
     2041 tagccacact ggcccccaaa gcgtcattcc attttcctcc catccaccct ggaaccactg
     2101 gtcctgggtg ccactgtgaa tattgtcctc cgaaccacta gaaaatgggg caagatggag
     2161 ctggccagga ctgccctgac tggagaggac ctgggcccag caaaggacac agccattcca
     2221 tgttgggtgc ttgtggcctg ccccatccct ccatccccca cgacccactt caggagcagc
     2281 agcttcagcc aggctgacgg ggcacttgct ccattgtccc tgcccttcac gagctgggcc
     2341 accccagaac cctgccacct gtgaccctct gcttactgct tcactgtctt ttctctatcc
     2401 tgaggagacc tgcaggcagc tctctcctgg gagctaagac ctcaaacccc acactctgga
     2461 ttgagacccc acctccttaa ctgtcctcct gctgccctgc agcctgcact ttgcacatgc
     2521 ttgtccccag cacagccacc ggcccttgcc cttctccaga cctcctgggt gctgtctgct
     2581 gtgcaaccag acctagggta cagtcgcccg gctggaacgt ggcactaccc cttccctcta
     2641 attaacccca aactcagacc caagaccgga gcctagaagg gcctgagcat catggttcca
     2701 tctgcccagg gctgggtcct gagcagctgg ccttcctgca ggaaaggaag gacgaggccc
     2761 agccgtgctg ggtaagcaaa ggccttttcc cctgctctca tgtcagccgg cctgggctgg
     2821 gttccaggct agagagtcag ccaggtggcc tgtgactggg tgaactggag ctggcttcct
     2881 gccagacgag cctcagccct cctgggcaag gggtgtgctt tccctgggga gtcttccccc
     2941 tactactcac cctcttggta cctccccaac cccagcactt tctgtcctat aatttgctta
     3001 aggagagtat aggctgccag ctcagccctg gataaattcc caccccctta agtttcactc
     3061 actttgtatc aacccagcag gctggtgttt ccttggcccc ttaaggtgtt tttcctcctg
     3121 agttcacagt tcttgtattc cttccacccc aacaagggga gataggtgcc tctgttcccc
     3181 attccacctg caccccagca gggctgggga taggcgagta tgggacattg tttctgtggg
     3241 tggggatggc tggactcccc aggttgggaa ggtccttgcc tagtttgtgt cttcctcagc
     3301 tagcaaaagt tggggctgtg gtcttagagc tgcctggtgt caggaccaga tcatttctat
     3361 aggttctgta gccgttgttt taatcagcag atgaatgtta gaagatgctg ccaaggcaag
     3421 gcagaacatg gctagagaag gttccggcag ctcagattcc atcctgccca gcaggtgcct
     3481 ggcactttaa gggactctgg cagctctgtt cctaggtgag gtgaccacca gaagatggac
     3541 agagccctag tgtgcttgtc tactaccttc cccagtcagc attgttttgg tctagttcta
     3601 aattccaggg ctccaaacca agcagttggt actgtcagga agactgcccc aaaccaagag
     3661 cccctgccta actcaagcca aggtctggga ctggatggcc actccagtag acgagagctg
     3721 ccacatcctc tgcttccagg cactgggcca ggataactta gctgaaaaca tgaccacaac
     3781 caaatgaaca ctggtggcag ccagaggcta agagcctttc ctcctgcgct cagtgatccc
     3841 cacgggtgcc cagagcacct ggacttcaaa ttctatatac aaagatagag gatatattag
     3901 aggtattttt gaaaaggaat tggtctatgc aatgccagtt tgggacctgt aagacagttt
     3961 aatgtttcta ttagagagat ataaaagatc tgcaatattt ttagggttct tttctggtta
     4021 ccctacagct gaccacgtgg tctggcagga tgagcaggcc catcttcttc tgtggggaga
     4081 atttgctttt gtgttattcc tttctaacca ggttaccact gcaccccatt ccgtgggctg
     4141 ttcatatctg tctcagctta taatagaaaa ttatgtcata tggggaaatc agcctagtgt
     4201 caatgtttgg tttgggggtg gaattaaatg ccgatgtttt tgtta
//
