LOCUS       NM_025462               1000 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus EEF1A lysine methyltransferase 4 (Eef1akmt4), mRNA.
ACCESSION   NM_025462
VERSION     NM_025462.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Katayama,S., Tomaru,Y., Kasukawa,T., Waki,K., Nakanishi,M.,
            Nakamura,M., Nishida,H., Yap,C.C., Suzuki,M., Kawai,J., Suzuki,H.,
            Carninci,P., Hayashizaki,Y., Wells,C., Frith,M., Ravasi,T.,
            Pang,K.C., Hallinan,J., Mattick,J., Hume,D.A., Lipovich,L.,
            Batalov,S., Engstrom,P.G., Mizuno,Y., Faghihi,M.A., Sandelin,A.,
            Chalk,A.M., Mottagui-Tabar,S., Liang,Z., Lenhard,B. and
            Wahlestedt,C.
  CONSRTM   RIKEN Genome Exploration Research Group; Genome Science Group
            (Genome Network Project Core Group); FANTOM Consortium
  TITLE     Antisense transcription in the mammalian transcriptome
  JOURNAL   Science 309 (5740), 1564-1566 (2005)
   PUBMED   16141073
REFERENCE   2  (bases 1 to 1000)
  AUTHORS   Carninci,P., Kasukawa,T., Katayama,S., Gough,J., Frith,M.C.,
            Maeda,N., Oyama,R., Ravasi,T., Lenhard,B., Wells,C., Kodzius,R.,
            Shimokawa,K., Bajic,V.B., Brenner,S.E., Batalov,S., Forrest,A.R.,
            Zavolan,M., Davis,M.J., Wilming,L.G., Aidinis,V., Allen,J.E.,
            Ambesi-Impiombato,A., Apweiler,R., Aturaliya,R.N., Bailey,T.L.,
            Bansal,M., Baxter,L., Beisel,K.W., Bersano,T., Bono,H., Chalk,A.M.,
            Chiu,K.P., Choudhary,V., Christoffels,A., Clutterbuck,D.R.,
            Crowe,M.L., Dalla,E., Dalrymple,B.P., de Bono,B., Della Gatta,G.,
            di Bernardo,D., Down,T., Engstrom,P., Fagiolini,M., Faulkner,G.,
            Fletcher,C.F., Fukushima,T., Furuno,M., Futaki,S., Gariboldi,M.,
            Georgii-Hemming,P., Gingeras,T.R., Gojobori,T., Green,R.E.,
            Gustincich,S., Harbers,M., Hayashi,Y., Hensch,T.K., Hirokawa,N.,
            Hill,D., Huminiecki,L., Iacono,M., Ikeo,K., Iwama,A., Ishikawa,T.,
            Jakt,M., Kanapin,A., Katoh,M., Kawasawa,Y., Kelso,J., Kitamura,H.,
            Kitano,H., Kollias,G., Krishnan,S.P., Kruger,A., Kummerfeld,S.K.,
            Kurochkin,I.V., Lareau,L.F., Lazarevic,D., Lipovich,L., Liu,J.,
            Liuni,S., McWilliam,S., Madan Babu,M., Madera,M., Marchionni,L.,
            Matsuda,H., Matsuzawa,S., Miki,H., Mignone,F., Miyake,S.,
            Morris,K., Mottagui-Tabar,S., Mulder,N., Nakano,N., Nakauchi,H.,
            Ng,P., Nilsson,R., Nishiguchi,S., Nishikawa,S., Nori,F., Ohara,O.,
            Okazaki,Y., Orlando,V., Pang,K.C., Pavan,W.J., Pavesi,G.,
            Pesole,G., Petrovsky,N., Piazza,S., Reed,J., Reid,J.F., Ring,B.Z.,
            Ringwald,M., Rost,B., Ruan,Y., Salzberg,S.L., Sandelin,A.,
            Schneider,C., Schonbach,C., Sekiguchi,K., Semple,C.A., Seno,S.,
            Sessa,L., Sheng,Y., Shibata,Y., Shimada,H., Shimada,K., Silva,D.,
            Sinclair,B., Sperling,S., Stupka,E., Sugiura,K., Sultana,R.,
            Takenaka,Y., Taki,K., Tammoja,K., Tan,S.L., Tang,S., Taylor,M.S.,
            Tegner,J., Teichmann,S.A., Ueda,H.R., van Nimwegen,E., Verardo,R.,
            Wei,C.L., Yagi,K., Yamanishi,H., Zabarovsky,E., Zhu,S., Zimmer,A.,
            Hide,W., Bult,C., Grimmond,S.M., Teasdale,R.D., Liu,E.T.,
            Brusic,V., Quackenbush,J., Wahlestedt,C., Mattick,J.S., Hume,D.A.,
            Kai,C., Sasaki,D., Tomaru,Y., Fukuda,S., Kanamori-Katayama,M.,
            Suzuki,M., Aoki,J., Arakawa,T., Iida,J., Imamura,K., Itoh,M.,
            Kato,T., Kawaji,H., Kawagashira,N., Kawashima,T., Kojima,M.,
            Kondo,S., Konno,H., Nakano,K., Ninomiya,N., Nishio,T., Okada,M.,
            Plessy,C., Shibata,K., Shiraki,T., Suzuki,S., Tagami,M., Waki,K.,
            Watahiki,A., Okamura-Oho,Y., Suzuki,H., Kawai,J. and Hayashizaki,Y.
  CONSRTM   FANTOM Consortium; RIKEN Genome Exploration Research Group and
            Genome Science Group (Genome Network Project Core Group)
  TITLE     The transcriptional landscape of the mammalian genome
  JOURNAL   Science 309 (5740), 1559-1563 (2005)
   PUBMED   16141072
  REMARK    Erratum:[Science. 2006 Mar 24;311(5768):1713]
REFERENCE   3  (bases 1 to 1000)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   4  (bases 1 to 1000)
  AUTHORS   Okazaki,Y., Furuno,M., Kasukawa,T., Adachi,J., Bono,H., Kondo,S.,
            Nikaido,I., Osato,N., Saito,R., Suzuki,H., Yamanaka,I.,
            Kiyosawa,H., Yagi,K., Tomaru,Y., Hasegawa,Y., Nogami,A.,
            Schonbach,C., Gojobori,T., Baldarelli,R., Hill,D.P., Bult,C.,
            Hume,D.A., Quackenbush,J., Schriml,L.M., Kanapin,A., Matsuda,H.,
            Batalov,S., Beisel,K.W., Blake,J.A., Bradt,D., Brusic,V.,
            Chothia,C., Corbani,L.E., Cousins,S., Dalla,E., Dragani,T.A.,
            Fletcher,C.F., Forrest,A., Frazer,K.S., Gaasterland,T.,
            Gariboldi,M., Gissi,C., Godzik,A., Gough,J., Grimmond,S.,
            Gustincich,S., Hirokawa,N., Jackson,I.J., Jarvis,E.D., Kanai,A.,
            Kawaji,H., Kawasawa,Y., Kedzierski,R.M., King,B.L., Konagaya,A.,
            Kurochkin,I.V., Lee,Y., Lenhard,B., Lyons,P.A., Maglott,D.R.,
            Maltais,L., Marchionni,L., McKenzie,L., Miki,H., Nagashima,T.,
            Numata,K., Okido,T., Pavan,W.J., Pertea,G., Pesole,G.,
            Petrovsky,N., Pillai,R., Pontius,J.U., Qi,D., Ramachandran,S.,
            Ravasi,T., Reed,J.C., Reed,D.J., Reid,J., Ring,B.Z., Ringwald,M.,
            Sandelin,A., Schneider,C., Semple,C.A., Setou,M., Shimada,K.,
            Sultana,R., Takenaka,Y., Taylor,M.S., Teasdale,R.D., Tomita,M.,
            Verardo,R., Wagner,L., Wahlestedt,C., Wang,Y., Watanabe,Y.,
            Wells,C., Wilming,L.G., Wynshaw-Boris,A., Yanagisawa,M., Yang,I.,
            Yang,L., Yuan,Z., Zavolan,M., Zhu,Y., Zimmer,A., Carninci,P.,
            Hayatsu,N., Hirozane-Kishikawa,T., Konno,H., Nakamura,M.,
            Sakazume,N., Sato,K., Shiraki,T., Waki,K., Kawai,J., Aizawa,K.,
            Arakawa,T., Fukuda,S., Hara,A., Hashizume,W., Imotani,K., Ishii,Y.,
            Itoh,M., Kagawa,I., Miyazaki,A., Sakai,K., Sasaki,D., Shibata,K.,
            Shinagawa,A., Yasunishi,A., Yoshino,M., Waterston,R., Lander,E.S.,
            Rogers,J., Birney,E. and Hayashizaki,Y.
  CONSRTM   FANTOM Consortium; RIKEN Genome Exploration Research Group Phase I
            & II Team
  TITLE     Analysis of the mouse transcriptome based on functional annotation
            of 60,770 full-length cDNAs
  JOURNAL   Nature 420 (6915), 563-573 (2002)
   PUBMED   12466851
REFERENCE   5  (bases 1 to 1000)
  AUTHORS   Kawai,J., Shinagawa,A., Shibata,K., Yoshino,M., Itoh,M., Ishii,Y.,
            Arakawa,T., Hara,A., Fukunishi,Y., Konno,H., Adachi,J., Fukuda,S.,
            Aizawa,K., Izawa,M., Nishi,K., Kiyosawa,H., Kondo,S., Yamanaka,I.,
            Saito,T., Okazaki,Y., Gojobori,T., Bono,H., Kasukawa,T., Saito,R.,
            Kadota,K., Matsuda,H., Ashburner,M., Batalov,S., Casavant,T.,
            Fleischmann,W., Gaasterland,T., Gissi,C., King,B., Kochiwa,H.,
            Kuehl,P., Lewis,S., Matsuo,Y., Nikaido,I., Pesole,G.,
            Quackenbush,J., Schriml,L.M., Staubli,F., Suzuki,R., Tomita,M.,
            Wagner,L., Washio,T., Sakai,K., Okido,T., Furuno,M., Aono,H.,
            Baldarelli,R., Barsh,G., Blake,J., Boffelli,D., Bojunga,N.,
            Carninci,P., de Bonaldo,M.F., Brownstein,M.J., Bult,C.,
            Fletcher,C., Fujita,M., Gariboldi,M., Gustincich,S., Hill,D.,
            Hofmann,M., Hume,D.A., Kamiya,M., Lee,N.H., Lyons,P.,
            Marchionni,L., Mashima,J., Mazzarelli,J., Mombaerts,P., Nordone,P.,
            Ring,B., Ringwald,M., Rodriguez,I., Sakamoto,N., Sasaki,H.,
            Sato,K., Schonbach,C., Seya,T., Shibata,Y., Storch,K.F., Suzuki,H.,
            Toyo-oka,K., Wang,K.H., Weitz,C., Whittaker,C., Wilming,L.,
            Wynshaw-Boris,A., Yoshida,K., Hasegawa,Y., Kawaji,H., Kohtsuki,S.
            and Hayashizaki,Y.
  CONSRTM   RIKEN Genome Exploration Research Group Phase II Team and the
            FANTOM Consortium
  TITLE     Functional annotation of a full-length mouse cDNA collection
  JOURNAL   Nature 409 (6821), 685-690 (2001)
   PUBMED   11217851
REFERENCE   6  (bases 1 to 1000)
  AUTHORS   Shibata,K., Itoh,M., Aizawa,K., Nagaoka,S., Sasaki,N., Carninci,P.,
            Konno,H., Akiyama,J., Nishi,K., Kitsunai,T., Tashiro,H., Itoh,M.,
            Sumi,N., Ishii,Y., Nakamura,S., Hazama,M., Nishine,T., Harada,A.,
            Yamamoto,R., Matsumoto,H., Sakaguchi,S., Ikegami,T., Kashiwagi,K.,
            Fujiwake,S., Inoue,K. and Togawa,Y.
  TITLE     RIKEN integrated sequence analysis (RISA) system--384-format
            sequencing pipeline with 384 multicapillary sequencer
  JOURNAL   Genome Res 10 (11), 1757-1771 (2000)
   PUBMED   11076861
REFERENCE   7  (bases 1 to 1000)
  AUTHORS   Carninci,P., Shibata,Y., Hayatsu,N., Sugahara,Y., Shibata,K.,
            Itoh,M., Konno,H., Okazaki,Y., Muramatsu,M. and Hayashizaki,Y.
  TITLE     Normalization and subtraction of cap-trapper-selected cDNAs to
            prepare full-length cDNA libraries for rapid discovery of new genes
  JOURNAL   Genome Res 10 (10), 1617-1630 (2000)
   PUBMED   11042159
REFERENCE   8  (bases 1 to 1000)
  AUTHORS   Carninci,P. and Hayashizaki,Y.
  TITLE     High-efficiency full-length cDNA cloning
  JOURNAL   Methods Enzymol 303, 19-44 (1999)
   PUBMED   10349636
REFERENCE   9  (bases 1 to 1000)
  AUTHORS   Bonaldo,M.F., Lennon,G. and Soares,M.B.
  TITLE     Normalization and subtraction: two approaches to facilitate gene
            discovery
  JOURNAL   Genome Res 6 (9), 791-806 (1996)
   PUBMED   8889548
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC115541.2 and BE956299.1.
            
            On Jan 5, 2007 this sequence version replaced NM_025462.1.
            
            Summary: This gene encodes a member of the lysine-specific
            methyltransferase (KMT) family. The encoded enzyme catalyzes the
            methylation of lysine-36 of the eukaryotic translation elongation
            factor 1 alpha. Methylation by this enzyme may affect endoplasmic
            reticulum-related processes. [provided by RefSeq, Jul 2017].
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-981               BC115541.2         3-983
            982-1000            BE956299.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16"
     gene            1..1000
                     /gene="Eef1akmt4"
                     /note="EEF1A lysine methyltransferase 4"
                     /db_xref="GeneID:110599566"
                     /db_xref="MGI:MGI:5903914"
     exon            1..220
                     /gene="Eef1akmt4"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..792
                     /gene="Eef1akmt4"
                     /EC_number="2.1.1.-"
                     /note="eukaryotic translation elongation factor 1 alpha
                     lysine specific methyltransferase 4"
                     /codon_start=1
                     /product="EEF1A lysine methyltransferase 4"
                     /protein_id="NP_079738.2"
                     /db_xref="CCDS:CCDS37290.1"
                     /db_xref="GeneID:110599566"
                     /db_xref="MGI:MGI:5903914"
                     /translation="MASPRTPVSPPELPEKNFQYRQVQYWDQRYKDAADSGPYEWFGD
                     FASFRALLEPELCPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSPVVVAAMQVRYA
                     HVPSLRWETMDVRALDFPSGSFDVVLEKGTLDAMLAGEPDPWNVSSEGVHTVDQVLSE
                     VSRLLVPGGRFISMTSAGPHFRIRHYAQSRYDWSLRHTTYSSGFHFHFYIMHKGRALS
                     VSQLALGAQILSSPSPPASPCFLQDSDNEDFLSAIQL"
     exon            221..504
                     /gene="Eef1akmt4"
                     /inference="alignment:Splign:2.1.0"
     exon            505..984
                     /gene="Eef1akmt4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      950..955
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Eef1akmt4"
                     /note="hexamer: AATACA"
     polyA_site      972
                     /gene="Eef1akmt4"
                     /note="major polyA site"
ORIGIN      
        1 cctggctgcg gcgctgccct gagcatggcc tctccccgga ctccggtgtc ccctccggag
       61 ttaccggaga agaacttcca gtaccgccaa gtccagtact gggaccagcg ctacaaagac
      121 gcggccgact ctggacccta cgagtggttc ggagacttcg cttccttccg tgccctccta
      181 gagccggagc tgtgtcctga ggaccgtatc ctcgtgctag gttgcgggaa cagtgccttg
      241 agctatgagc tgttccttgg aggcttccct aatgtgacca gtgtggatta ctctccagta
      301 gtggtggcag ccatgcaagt tcgctatgcc catgtaccca gtctacgctg ggagaccatg
      361 gatgttcgag cactggactt ccctagtggg tcttttgatg ttgtcctcga gaagggtact
      421 ctggatgcca tgctggctgg ggagccagat ccctggaatg tatcttctga aggtgtccac
      481 actgtggacc aggtgctgag tgaggtaagc cggttgctag ttcctggagg ccgattcatc
      541 tcaatgactt ctgcaggtcc ccactttagg atcagacact atgctcaatc ccgttatgac
      601 tggtcactga ggcatacaac ctatagcagt ggttttcatt tccactttta catcatgcat
      661 aagggcagag cgctcagtgt gtcccagctg gccctggggg cccaaatcct ctcatccccc
      721 agccctcctg cctcaccctg cttcctccaa gactcagaca acgaggactt cctcagtgcc
      781 attcagctgt gagactggaa gtgtgatctc caagtcctcc ctgcctttgt gcattaggct
      841 cctagggagt tggaattccc agtttggggc tggggattgg ttgctgggta ctcaaatcca
      901 gaggtcttgt gcataaaaca gtgccagtgg gatcaagccc atgtgaacca atacagtgtg
      961 agtccaacta aatcccagat cccaaaaaaa aaaaaaaaaa
//
