LOCUS       NM_001205036             699 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus EEF1A lysine methyltransferase 3 (Eef1akmt3), mRNA.
ACCESSION   NM_001205036 XM_003085736
VERSION     NM_001205036.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 699)
  AUTHORS   Malecki,J., Aileni,V.K., Ho,A.Y.Y., Schwarz,J., Moen,A.,
            Sorensen,V., Nilges,B.S., Jakobsson,M.E., Leidel,S.A. and
            Falnes,P.O.
  TITLE     The novel lysine specific methyltransferase METTL21B affects mRNA
            translation through inducible and dynamic methylation of Lys-165 in
            human eukaryotic elongation factor 1 alpha (eEF1A)
  JOURNAL   Nucleic Acids Res 45 (8), 4370-4389 (2017)
   PUBMED   28108655
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134329.3.
            
            On Mar 18, 2011 this sequence version replaced XM_003085736.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-177               AC134329.3         43602-43778
            178-289             AC134329.3         43897-44008
            290-699             AC134329.3         51682-52091
FEATURES             Location/Qualifiers
     source          1..699
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 74.5 cM"
     gene            1..699
                     /gene="Eef1akmt3"
                     /gene_synonym="EG546486; Fam119b; Gm16109; Mettl21b"
                     /note="EEF1A lysine methyltransferase 3"
                     /db_xref="GeneID:100504608"
                     /db_xref="MGI:MGI:3645330"
     CDS             1..699
                     /gene="Eef1akmt3"
                     /gene_synonym="EG546486; Fam119b; Gm16109; Mettl21b"
                     /EC_number="2.1.1.-"
                     /note="Methyltransferase-like protein 21B; Protein-lysine
                     methyltransferase METTL21B; methyltransferase like 21B;
                     family with sequence similarity 119, member B"
                     /codon_start=1
                     /product="EEF1A lysine methyltransferase 3"
                     /protein_id="NP_001191965.1"
                     /db_xref="CCDS:CCDS56752.1"
                     /db_xref="GeneID:100504608"
                     /db_xref="MGI:MGI:3645330"
                     /translation="MASSRTDPETEPESVFPREIRLFTDSYSESSRFCFCGHELSITQ
                     NFGSRLGVAARVWDAALSLCDYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTI
                     TDLPVALEQIQDNVHANVPPGGRARVCALSWGIDQHVFPGNYDLVLGADIVYLEPTFP
                     LLLGTLRHLCGPHGTIYLASKMRAEHGAETFFRRLLPQHFHLELAQRDEDVNVNIYRA
                     RHREVAPAGQHPFC"
     exon            1..177
                     /gene="Eef1akmt3"
                     /gene_synonym="EG546486; Fam119b; Gm16109; Mettl21b"
                     /inference="alignment:Splign:2.1.0"
     exon            178..289
                     /gene="Eef1akmt3"
                     /gene_synonym="EG546486; Fam119b; Gm16109; Mettl21b"
                     /inference="alignment:Splign:2.1.0"
     exon            290..699
                     /gene="Eef1akmt3"
                     /gene_synonym="EG546486; Fam119b; Gm16109; Mettl21b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggccagct ctcgcaccga tccggaaact gagcccgaat ccgtgttccc acgggagatc
       61 cggctcttca cagactctta ctcagagagc agccggttct gcttctgtgg gcacgagctg
      121 agcatcacgc agaactttgg gtcgcgcctt ggggtggcgg cacgcgtgtg ggatgcggct
      181 ctgagcctgt gtgactattt cgagagtcaa aatgtggatt ttcgaggcaa gaaggtgatc
      241 gaactgggcg cggggacggg catcgtggga atcttggcgg cgctgcaggg gggggatgtt
      301 accatcactg atttgccagt ggcactagag caaatccagg ataacgtcca cgccaatgtg
      361 ccacccggag gccgggctcg ggtgtgcgcc ttgtcctggg gaattgacca gcatgtcttt
      421 cctggaaact atgacttggt gctgggggcg gatatcgtgt acctggaacc taccttcccg
      481 ctactgttgg ggactctccg acacctgtgt gggccccacg gcaccatcta cctggcctcc
      541 aagatgagag cagaacacgg ggcagagacc ttctttcggc gcctcctgcc ccagcacttc
      601 cacctggagc tggcccagcg ggatgaggat gtgaatgtca acatctatag ggccaggcac
      661 agggaggtgg cacctgccgg acagcacccc ttctgttga
//
