LOCUS       NM_026526                852 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus EEF1A alpha lysine methyltransferase 1 (Eef1akmt1),
            mRNA.
ACCESSION   NM_026526
VERSION     NM_026526.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 852)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 852)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   4  (bases 1 to 852)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154675.2.
            
            On Feb 15, 2019 this sequence version replaced NM_026526.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC051925.1, AK012083.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164142
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                AC154675.2         191897-191936       c
            41-203              AC154675.2         186276-186438       c
            204-286             AC154675.2         178388-178470       c
            287-567             AC154675.2         170716-170996       c
            568-852             AC154675.2         169949-170233       c
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 30.1 cM"
     gene            1..852
                     /gene="Eef1akmt1"
                     /gene_synonym="2510005D08Rik; Ayu21-96; Gt(pU21)96Imeg;
                     GtAyu21-96; N6amt2"
                     /note="EEF1A alpha lysine methyltransferase 1"
                     /db_xref="GeneID:68043"
                     /db_xref="MGI:MGI:1915293"
     exon            1..40
                     /gene="Eef1akmt1"
                     /gene_synonym="2510005D08Rik; Ayu21-96; Gt(pU21)96Imeg;
                     GtAyu21-96; N6amt2"
                     /inference="alignment:Splign:2.1.0"
     exon            41..203
                     /gene="Eef1akmt1"
                     /gene_synonym="2510005D08Rik; Ayu21-96; Gt(pU21)96Imeg;
                     GtAyu21-96; N6amt2"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..704
                     /gene="Eef1akmt1"
                     /gene_synonym="2510005D08Rik; Ayu21-96; Gt(pU21)96Imeg;
                     GtAyu21-96; N6amt2"
                     /note="n(6)-adenine-specific DNA methyltransferase 2;
                     Gt(Ayu21)96Imeg; protein-lysine N-methyltransferase
                     N6amt2; N-6 adenine-specific DNA methyltransferase 2
                     (putative); eukaryotic translation elongation factor 1
                     alpha lysine methyltransferase 1"
                     /codon_start=1
                     /product="EEF1A lysine methyltransferase 1"
                     /protein_id="NP_080802.2"
                     /db_xref="CCDS:CCDS27157.2"
                     /db_xref="GeneID:68043"
                     /db_xref="MGI:MGI:1915293"
                     /translation="MSESEDDDIPQLSSHTLAALQEFYAEQKQSVNPRGDDKYNVGVI
                     EENWQLSQFWYSQDTALRLAREAIDAAGEGGRIACVSAPSVYQKLRELCREDSSVYIF
                     EYDRRFAIYGDEFIFYDYNHPLELPERIAAHSFDLVVADPPYLSEECLRKTSETIQFL
                     TRGKILLCTGAIMEEQAAQLLGVKMCKFIPEHSRNLANEFRCYTNYDSGLDCEA"
     exon            204..286
                     /gene="Eef1akmt1"
                     /gene_synonym="2510005D08Rik; Ayu21-96; Gt(pU21)96Imeg;
                     GtAyu21-96; N6amt2"
                     /inference="alignment:Splign:2.1.0"
     exon            287..567
                     /gene="Eef1akmt1"
                     /gene_synonym="2510005D08Rik; Ayu21-96; Gt(pU21)96Imeg;
                     GtAyu21-96; N6amt2"
                     /inference="alignment:Splign:2.1.0"
     exon            568..852
                     /gene="Eef1akmt1"
                     /gene_synonym="2510005D08Rik; Ayu21-96; Gt(pU21)96Imeg;
                     GtAyu21-96; N6amt2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      831..836
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Eef1akmt1"
                     /gene_synonym="2510005D08Rik; Ayu21-96; Gt(pU21)96Imeg;
                     GtAyu21-96; N6amt2"
                     /note="hexamer: AATAAA"
     polyA_site      851
                     /gene="Eef1akmt1"
                     /gene_synonym="2510005D08Rik; Ayu21-96; Gt(pU21)96Imeg;
                     GtAyu21-96; N6amt2"
                     /note="major polyA site"
ORIGIN      
        1 accccacccc cgcactgtga cgactgcgca tgcgtcagtg gtcgcagaca ctttgtgaaa
       61 tgagtgagtc agaagacgac gacatacccc agctctcttc ccatacctta gcagctctcc
      121 aggagtttta tgctgagcag aagcaatccg tcaaccccag aggggatgat aaatataacg
      181 ttggggtaat agaggagaac tggcagctga gccagttctg gtacagtcag gacactgctt
      241 tgcgacttgc acgggaagcg atcgatgctg ctggagaagg aggcagaatc gcgtgtgtga
      301 gcgcgccaag cgtgtaccag aagctccggg agctctgtag ggaagacagc tctgtctaca
      361 tctttgaata cgacagaaga ttcgccatat atggggatga atttatcttc tatgattaca
      421 accatccact ggagttgcct gagagaatcg ctgcgcatag ctttgacctt gtggttgcag
      481 accctcctta cctgtctgag gaatgtctca ggaagacatc tgaaacgatc cagtttctga
      541 ctcggggcaa gattctgctg tgcacaggag ccatcatgga agagcaggca gctcagctcc
      601 tgggtgtgaa gatgtgcaag tttattccgg aacactcccg aaacttggcc aatgagttcc
      661 gctgttacac gaactatgac tctgggctgg actgtgaagc ctaaattcac atggcagcag
      721 ttccatagag gactccacat tcatttccca gttctcgttc tgtggaaaca ttgtgacctc
      781 cccctttctc tgccctggct gggactcccc tggcttattt ttcaaaataa aataaaactt
      841 ctccatgctg at
//
