LOCUS       NM_010106               1790 bp    mRNA    linear   ROD 08-OCT-2024
DEFINITION  Mus musculus eukaryotic translation elongation factor 1 alpha 1
            (Eef1a1), mRNA.
ACCESSION   NM_010106 XM_203909
VERSION     NM_010106.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1790)
  AUTHORS   Wang,Y., Luan,T., Wang,L., Feng,D., Dong,Y., Li,S., Yang,H.,
            Chen,Y., Fei,Y., Lin,L., Pan,J., Zhong,Z. and Zhao,W.
  TITLE     N-Acetylcysteine Inhibits Coxsackievirus B3 Replication by
            Downregulating Eukaryotic Translation Elongation Factor 1 Alpha 1
  JOURNAL   Viruses 16 (9), 1503 (2024)
   PUBMED   39339978
  REMARK    GeneRIF: N-Acetylcysteine Inhibits Coxsackievirus B3 Replication by
            Downregulating Eukaryotic Translation Elongation Factor 1 Alpha 1.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1790)
  AUTHORS   Yang,E.J., Frolinger,T., Iqbal,U., Estill,M., Shen,L.,
            Trageser,K.J. and Pasinetti,G.M.
  TITLE     The role of the Toll like receptor 4 signaling in sex-specific
            persistency of depression-like behavior in response to chronic
            stress
  JOURNAL   Brain Behav Immun 115, 169-178 (2024)
   PUBMED   37838079
REFERENCE   3  (bases 1 to 1790)
  AUTHORS   Davies,F.C.J., Marshall,G.F., Pegram,E., Gadd,D. and Abbott,C.M.
  TITLE     Endogenous epitope tagging of eEF1A2 in mice reveals early
            embryonic expression of eEF1A2 and subcellular compartmentalisation
            of neuronal eEF1A1 and eEF1A2
  JOURNAL   Mol Cell Neurosci 126, 103879 (2023)
   PUBMED   37429391
  REMARK    GeneRIF: Endogenous epitope tagging of eEF1A2 in mice reveals early
            embryonic expression of eEF1A2 and subcellular compartmentalisation
            of neuronal eEF1A1 and eEF1A2.
REFERENCE   4  (bases 1 to 1790)
  AUTHORS   Sun,H., Lin,W., Tang,Y., Tu,H., Chen,T., Zhou,J., Wang,D., Xu,Q.,
            Niu,J., Dong,W., Liu,S., Ni,X., Yang,W., Zhao,Y., Ying,L.,
            Zhang,J., Li,X., Mohammadi,M., Shen,W.L. and Huang,Z.
  TITLE     Sustained remission of type 2 diabetes in rodents by centrally
            administered fibroblast growth factor 4
  JOURNAL   Cell Metab 35 (6), 1022-1037 (2023)
   PUBMED   37167965
REFERENCE   5  (bases 1 to 1790)
  AUTHORS   Wu,Q., Sacomboio,E., Valente de Souza,L., Martins,R., Kitoko,J.,
            Cardoso,S., Ademolue,T.W., Paixao,T., Lehtimaki,J., Figueiredo,A.,
            Norden,C., Tharaux,P.L., Weiss,G., Wang,F., Ramos,S. and
            Soares,M.P.
  TITLE     Renal control of life-threatening malarial anemia
  JOURNAL   Cell Rep 42 (2), 112057 (2023)
   PUBMED   36735532
REFERENCE   6  (bases 1 to 1790)
  AUTHORS   Whiteheart,S.W., Shenbagamurthi,P., Chen,L., Cotter,R.J. and
            Hart,G.W.
  TITLE     Murine elongation factor 1 alpha (EF-1 alpha) is
            posttranslationally modified by novel amide-linked
            ethanolamine-phosphoglycerol moieties. Addition of
            ethanolamine-phosphoglycerol to specific glutamic acid residues on
            EF-1 alpha
  JOURNAL   J Biol Chem 264 (24), 14334-14341 (1989)
   PUBMED   2569467
REFERENCE   7  (bases 1 to 1790)
  AUTHORS   Lu,X.A. and Werner,D.
  TITLE     The complete cDNA sequence of mouse elongation factor 1 alpha (EF 1
            alpha) mRNA
  JOURNAL   Nucleic Acids Res 17 (1), 442 (1989)
   PUBMED   2911475
REFERENCE   8  (bases 1 to 1790)
  AUTHORS   Reddy,N.S., Roth,W.W., Bragg,P.W. and Wahba,A.J.
  TITLE     Isolation and mapping of a gene for protein synthesis initiation
            factor 4A and its expression during differentiation of murine
            erythroleukemia cells
  JOURNAL   Gene 70 (2), 231-243 (1988)
   PUBMED   3215517
REFERENCE   9  (bases 1 to 1790)
  AUTHORS   Rao,T.R. and Slobin,L.I.
  TITLE     Structure of the amino-terminal end of mammalian elongation factor
            Tu
  JOURNAL   Nucleic Acids Res 14 (5), 2409 (1986)
   PUBMED   3960725
  REMARK    Erratum:[Nucleic Acids Res 1986 Aug 11;14(15):6344]
REFERENCE   10 (bases 1 to 1790)
  AUTHORS   Brands,J.H., Maassen,J.A., van Hemert,F.J., Amons,R. and Moller,W.
  TITLE     The primary structure of the alpha subunit of human elongation
            factor 1. Structural aspects of guanine-nucleotide-binding sites
  JOURNAL   Eur J Biochem 155 (1), 167-171 (1986)
   PUBMED   3512269
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158987.3.
            
            On Feb 22, 2007 this sequence version replaced NM_010106.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK141243.1, SRR1660815.147408.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164133
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                AC158987.3         121218-121303       c
            87-264              AC158987.3         120090-120267       c
            265-444             AC158987.3         119820-119999       c
            445-741             AC158987.3         119431-119727       c
            742-892             AC158987.3         119203-119353       c
            893-1149            AC158987.3         118857-119113       c
            1150-1384           AC158987.3         118537-118771       c
            1385-1790           AC158987.3         118032-118437       c
FEATURES             Location/Qualifiers
     source          1..1790
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 43.65 cM"
     gene            1..1790
                     /gene="Eef1a1"
                     /note="eukaryotic translation elongation factor 1 alpha 1"
                     /db_xref="GeneID:13627"
                     /db_xref="MGI:MGI:1096881"
     exon            1..86
                     /gene="Eef1a1"
                     /inference="alignment:Splign:2.1.0"
     exon            87..264
                     /gene="Eef1a1"
                     /inference="alignment:Splign:2.1.0"
     exon            265..444
                     /gene="Eef1a1"
                     /inference="alignment:Splign:2.1.0"
     exon            445..741
                     /gene="Eef1a1"
                     /inference="alignment:Splign:2.1.0"
     exon            742..892
                     /gene="Eef1a1"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1149
                     /gene="Eef1a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1384
                     /gene="Eef1a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1385..1790
                     /gene="Eef1a1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1670
                     /gene="Eef1a1"
                     /note="major polyA site"
ORIGIN      
        1 ttcccgaggg tgggggagaa cggtatataa gtgcggcagt cgccttggac gttctttttc
       61 gcaacgggtt tgccgtcaga acgcaggtgt tgtgaaaacc accgctaatt caaagcaaaa
      121 atgggaaagg aaaagactca catcaacatc gtcgtaatcg gacacgtaga ttccggcaag
      181 tccaccacaa ccggccacct gatctacaaa tgtggtggaa tcgacaagcg aaccatcgaa
      241 aagtttgaga aggaggctgc tgagatggga aagggctcct tcaagtacgc ctgggtctta
      301 gacaaactga aagctgagcg tgagcgtggt atcactattg acatctccct gtggaaattc
      361 gagaccagca aatactatgt gaccatcatt gatgccccag gacacagaga cttcatcaaa
      421 aacatgatta caggcacatc ccaggctgac tgtgctgtcc tgattgttgc tgctggtgtt
      481 ggtgaatttg aagctggtat ctccaagaac gggcagaccc gcgagcatgc tcttctggct
      541 tacaccctgg gtgtgaaaca gctgattgtt ggtgtcaaca aaatggattc caccgagcca
      601 ccatacagtc agaagagata cgaggaaatc gttaaggaag tcagcaccta cattaagaaa
      661 attggctaca accctgacac agtagcattt gtgccaattt ctggttggaa tggtgacaac
      721 atgctggagc caagtgctaa tatgccttgg ttcaagggat ggaaagtcac ccgcaaagat
      781 ggcagtgcca gtggcaccac gctgctggaa gctttggatt gtatcctacc accaactcgt
      841 ccaactgaca agcccctgcg actgcccctc caggatgtct ataaaattgg aggcattggc
      901 actgtccctg tgggccgagt ggagactggt gttctcaagc ctggcatggt ggttaccttt
      961 gctccagtca atgtaacaac tgaagtcaag tctgttgaaa tgcaccatga agctttgagt
     1021 gaagctcttc ctggggacaa tgtgggcttc aatgtaaaga acgtgtcggt caaagatgtt
     1081 agacgaggca atgttgctgg tgacagcaaa aacgacccac caatggaagc agctggcttc
     1141 actgctcagg tgattatcct gaaccatcca ggccaaatca gtgctggcta cgctcctgtt
     1201 ctggattgtc acacagccca catagcatgc aagtttgctg agcttaaaga aaagatcgat
     1261 cgtcgttctg gtaagaagct ggaagatggc cccaagttcc tgaagtctgg cgatgctgcc
     1321 attgttgata tggtccctgg caagcccatg tgtgttgaga gcttctctga ctaccctcca
     1381 cttggtcgct ttgctgttcg tgacatgagg cagacagttg ctgtgggtgt catcaaagct
     1441 gtggacaaga aggctgctgg agctggcaaa gtcaccaagt ctgcccagaa agctcagaag
     1501 gctaaatgaa tattacccct aacacctgcc accccagtct taatcagtgg tggaagaacg
     1561 gtctcagaac tgtttgtctc aattggccat ttaagtttaa tagtaaaaga ctggttaatg
     1621 ataacaatgc atcgtaaaac cttcagaagg aaagaatgtt gtggaccatt ttttttgtgt
     1681 gtggcagttt taagttatta gttttcaaaa tcagtacttt ttaatggaaa caacttgacc
     1741 aaaaatctgt cacagaattt tgagaccatt aaaacaagtt taatgagaaa
//
