LOCUS       NM_178115               5284 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus erythroid differentiation regulatory factor 1 (Edrf1),
            transcript variant 1, mRNA.
ACCESSION   NM_178115
VERSION     NM_178115.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5284)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 5284)
  AUTHORS   Friedel,R.H., Seisenberger,C., Kaloff,C. and Wurst,W.
  TITLE     EUCOMM--the European conditional mouse mutagenesis program
  JOURNAL   Brief Funct Genomic Proteomic 6 (3), 180-185 (2007)
   PUBMED   17967808
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127348.4.
            
            On Jun 8, 2022 this sequence version replaced NM_178115.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC072596.1, AK144179.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-231               AC127348.4         151862-152092       c
            232-440             AC127348.4         150670-150878       c
            441-507             AC127348.4         149039-149105       c
            508-633             AC127348.4         148366-148491       c
            634-758             AC127348.4         146013-146137       c
            759-915             AC127348.4         145636-145792       c
            916-1017            AC127348.4         142694-142795       c
            1018-1139           AC127348.4         142319-142440       c
            1140-1251           AC127348.4         141488-141599       c
            1252-1399           AC127348.4         139360-139507       c
            1400-1508           AC127348.4         139176-139284       c
            1509-1620           AC127348.4         138650-138761       c
            1621-1881           AC127348.4         137592-137852       c
            1882-1953           AC127348.4         135827-135898       c
            1954-2104           AC127348.4         135378-135528       c
            2105-2293           AC127348.4         133102-133290       c
            2294-2494           AC127348.4         132617-132817       c
            2495-2713           AC127348.4         131141-131359       c
            2714-2937           AC127348.4         129491-129714       c
            2938-3096           AC127348.4         127844-128002       c
            3097-3246           AC127348.4         127555-127704       c
            3247-3400           AC127348.4         126271-126424       c
            3401-3516           AC127348.4         123802-123917       c
            3517-3668           AC127348.4         122094-122245       c
            3669-5284           AC127348.4         116804-118419       c
FEATURES             Location/Qualifiers
     source          1..5284
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 77.18 cM"
     gene            1..5284
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /note="erythroid differentiation regulatory factor 1"
                     /db_xref="GeneID:214764"
                     /db_xref="MGI:MGI:1919831"
     exon            1..231
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..3843
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     erythroid differentiation-related factor 1"
                     /codon_start=1
                     /product="erythroid differentiation-related factor 1
                     isoform 1"
                     /protein_id="NP_835216.3"
                     /db_xref="CCDS:CCDS21932.2"
                     /db_xref="GeneID:214764"
                     /db_xref="MGI:MGI:1919831"
                     /translation="MMGDPKEAGAEASPSGAAARGGLSLLSQADSEEPSAQGSALFLG
                     GNEVKSRAVVKYSSAPPRTAFARLEEKTDLKLPPANWLRESAKLGPAGTTILGNSKKS
                     KPFSSFGMAYDFIDSVGNDVDVVSDSENIKKLLKIPYSKSHVSMAVHRIGRTLLLDEL
                     DIQELFMRSSQTGDWTWLKEFYQRLIDQKWQRKKKSKEHWYQKAILSKFLYYSINGDG
                     AAQPVPSPAEQEESSSSQQTHESEGAAWPAPFEMPSSVSEDPSASSQGREPLEPSCIV
                     GHVASAPKEQNLTTLFNDGENSQGLKNDFVRNILWTFEDIHMLVGSNMPIFGGGRYPA
                     VSLRLRDNNKPINVLTGIDYWLDNLICNVPELVMCFHVNGIVQKYEMIKTEEIPNLEN
                     SNFSTKVIKDIAQNILSFLKSNCTKEGHTYWLFKASGSDIVKLYDLTTLCEETEDKYQ
                     NPFTMPVAILLYKVACNMMMKKNQNKKHYGTIRTLLLNCVKLLDKSRHPQIIASANYM
                     LSELFQLDEPKKEESSDSPLNENSDESYSEEEEEMADSDENGSYSTSSDPADDNKAVA
                     IIKSVGELSVPEKYKSIHQIRPSCAFPVCHDTEERCRLVLSYVLEGLKSVDSSIKKES
                     DLPAADPSTPIPLKYEDESTRGGPEGLEKQMALFLDKMGSIQKGSCSGQSGMTPGSWQ
                     HKMKLQLILKSSKAYYILSDAAMSLQKYGRALRYIKLALQSHDTYCCLCTNMLSEVLL
                     FLSQYLTLCGDIQLMLAQNANNRAAHLEEFNYQTKEDQEILHSLHRESSCQGFAWATD
                     LSTDLESQLSVSCKCYEAANEILQFSDLKSQNPEHYVQVLKRMGNIRNEIGVFYMNQA
                     AALQGERVVSKSVSAAEQQLWKKSFSCFEKGIHNFESIDDATNAALLLCNTGRLMRVC
                     AQAHCGAEDEFKREFSPEEGLYYSKAVDYYLKALRSLGTRDMHPIVWDSVNWELSTTY
                     FTMATLQQDYAPLSRKAQEQIEKEVSEAMMKSLKHCDVDSATARQPLCQYRAATIHHR
                     LASMYHSCLRNQVGDEHLRKQHRVLADLHYSKAAKLFQLLKDAPCELLRVQLERVAFA
                     EFQMSSQNSNVGKLKTLSGALDIMVRTEHAFQLIRKELVEECDQPKNDEATPAADSSP
                     NLNREEVIKLLSIFESRLSFLLLQSIKLMSSSKRKMSSNAEEDIVLQTNKQIYSQLLR
                     ATANRNSTLLERIEVVICLLEQLASGSSRSSGSAVP"
     exon            232..440
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            441..507
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            508..633
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            634..758
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            759..915
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1017
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1139
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1140..1251
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1399
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1508
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..1620
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..1881
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1882..1953
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1954..2104
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2105..2293
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2294..2494
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2495..2713
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2714..2937
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2938..3096
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3097..3246
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3247..3400
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3401..3516
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3517..3668
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3669..5284
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3924..3929
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3949
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
     regulatory      4463..4468
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /note="hexamer: AATAAG"
     polyA_site      4484
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /note="major polyA site"
     regulatory      5255..5260
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5284
                     /gene="Edrf1"
                     /gene_synonym="2700050L05Rik"
ORIGIN      
        1 ggaagtgcga gccgctgagt gtccgagtcg ctcgctctga ggttctcctg cgactctggg
       61 cccgcgttcc tgtcgccgcc tccagggctc gcgcgtctgg tcgcctcccc agggtcggaa
      121 atgatggggg accccaagga agcaggagcc gaggcttctc cttcaggggc ggccgcccga
      181 ggagggctca gcctcctgtc ccaggcggac tccgaggagc cttctgcaca gggatcggcc
      241 ttatttcttg gaggcaacga agtgaaaagc agagctgtgg taaaatactc ttctgcccct
      301 cctcgaacag cgtttgcacg tctcgaagaa aaaacagact tgaaactccc acctgccaac
      361 tggttacgag agagtgccaa actagggcca gcaggaacca ccattcttgg caatagtaag
      421 aaaagcaagc cgttttcaag tttcggcatg gcgtatgact tcattgactc ggtgggaaat
      481 gatgtggatg tcgtctccga ctcagaaaac ataaaaaagc tcctgaagat tccctacagc
      541 aagtcccacg tgagcatggc tgtgcaccgc ataggaagga ccctcttact agatgagctg
      601 gacattcaag aactctttat gaggtcatct cagactggtg attggacatg gttgaaagag
      661 ttctatcaaa gactgatcga tcagaagtgg cagaggaaga agaaaagcaa ggagcactgg
      721 tatcagaagg ctattctttc caagttcttg tactacagca tcaatggtga tggagctgcg
      781 cagcctgtcc cgtctcctgc agaacaagaa gagtcatcga gttctcagca gacacatgag
      841 tctgaagggg ccgcctggcc tgctcccttt gaaatgccct cttccgtgtc tgaggatccc
      901 agtgcttcca gtcagggcag ggagcctctt gagccctcat gcatagtggg gcatgtggcc
      961 tcagcaccta aagagcaaaa ccttactact ttgttcaatg acggggagaa cagtcagggt
     1021 cttaaaaatg atttcgtccg gaatatcctg tggacttttg aagatattca tatgctagtt
     1081 gggtctaaca tgcctatatt tggtggaggc agatatccag cagttagctt acgtctcagg
     1141 gataacaaca aaccgattaa cgtgttaact ggaatagact attggttgga caacctgata
     1201 tgcaatgttc cagagctcgt gatgtgcttc catgttaacg ggatcgtaca gaaatatgaa
     1261 atgataaaga cagaagaaat ccccaatttg gaaaactcta atttttctac caaagttata
     1321 aaagacattg cacaaaatat tttatcattt cttaaatcta attgtaccaa agaagggcat
     1381 acctattggc tctttaaagc aagcggcagt gatattgtga aactctacga cctcacgact
     1441 ctgtgtgaag aaactgaaga caagtaccag aacccattca caatgccagt ggctatcctc
     1501 ttatacaagg ttgcttgtaa catgatgatg aagaaaaatc aaaacaagaa acactatgga
     1561 actattagaa cattgcttct caactgtgtt aagttgttgg acaaaagcag acatcctcaa
     1621 attattgctt cagccaacta catgctttca gagcttttcc agctggatga gcctaaaaag
     1681 gaggaaagtt cagactcccc tttaaatgag aattcggatg aaagctacag tgaagaggag
     1741 gaggagatgg cagacagtga tgagaatgga tcctacagca ccagctctga cccagcagat
     1801 gacaacaagg cagtggctat cattaagtct gttggagaac tgtcagtacc ggaaaaatac
     1861 aagtcgattc atcagatcag acccagttgt gcatttcccg tttgccatga cacagaagag
     1921 cgctgtcgac tcgtccttag ctatgtgttg gagggtttaa aatctgtaga tagtagcatc
     1981 aaaaaagaaa gcgaccttcc agcagctgac cccagcactc ctatcccctt aaaatatgaa
     2041 gatgaatcca caaggggtgg ccctgagggg ctggagaagc agatggcctt gttcctggac
     2101 aaaatgggct ccattcagaa gggcagttgt tctgggcagt ctggaatgac ccctggttct
     2161 tggcaacata aaatgaaact tcagctgatt ctcaagtcat caaaggccta ctacattttg
     2221 tcagatgctg ccatgagtct tcagaagtat ggaagagcat tgagatacat taagctagct
     2281 ctacagagcc atgatactta ctgctgcctc tgcaccaaca tgctttctga agtgctgctg
     2341 ttcctctctc aatacctgac actttgcggc gacatccaac tcatgctggc ccagaatgca
     2401 aataaccgag cagcacacct cgaggagttt aattaccaaa caaaagaaga ccaggagatc
     2461 ctccacagtc tccacagaga gtccagctgc cagggatttg catgggcaac agatctatct
     2521 acagacttag aaagtcaact ctcagttagt tgtaaatgtt atgaggctgc taatgaaatc
     2581 ttgcaattca gcgacttaaa aagtcagaat ccagaacact atgtacaggt gttgaagaga
     2641 atgggaaaca ttagaaatga aatcggtgta ttctacatga atcaggctgc tgcactgcag
     2701 ggtgagcgag tagtgagcaa atctgtgtct gctgcagagc aacaattgtg gaaaaaaagc
     2761 ttttcttgtt ttgaaaaggg gattcacaac tttgagtcga ttgatgatgc tacaaatgct
     2821 gcccttctgc tgtgcaacac gggaagactc atgcgggtct gtgcgcaggc gcactgcggt
     2881 gcagaggatg agttcaaacg ggagttctct ccagaggagg gcttgtatta cagcaaggcc
     2941 gttgattact atttgaaggc tctgaggtca ttgggaacga gagacatgca cccaattgtt
     3001 tgggattctg tgaactggga attgtccact acatacttca ccatggcgac tctgcagcaa
     3061 gattatgctc cattatccag aaaagctcag gagcagattg agaaagaagt gagcgaggct
     3121 atgatgaagt ccctgaagca ctgcgatgtt gactcagcaa ctgctcggca gcccctctgt
     3181 cagtaccgag ctgcgaccat ccatcacagg ctggcttcca tgtaccacag ctgtctgagg
     3241 aaccaggttg gtgatgagca tcttaggaag cagcaccgag tgctggcaga tctccactac
     3301 agcaaagctg cgaagctctt tcagcttctc aaagacgctc cctgtgaact gcttagagtg
     3361 cagctagaaa gggtggcatt tgcagaattt cagatgagca gtcagaatag caatgttgga
     3421 aagttaaaaa cattatctgg ggcacttgat atcatggtga gaacggagca tgcgttccag
     3481 ctcatccgga aggagcttgt agaggaatgt gaccagccca agaatgatga ggctacaccg
     3541 gctgctgatt cttcacctaa tcttaatcga gaagaagtga tcaaactcct tagtatattt
     3601 gaatctcgtc tgtcattcct tctccttcaa tccatcaaac tgatgtcgtc atctaaaagg
     3661 aaaatgagca gtaacgctga agaagacata gtcctccaaa ccaacaagca gatttactcc
     3721 cagcttttga gagcgactgc caacagaaac tcaactctgc tggaaagaat tgaagtcgtc
     3781 atctgtttgc tggagcagct tgcctccggt agcagccgat cgagtggcag tgctgtcccc
     3841 tgactgcagt ggtactggag gactgtcttg tcagtgcctt cccgtcctgg agctgtctgt
     3901 ctgtccactc ggtgctgaga cttattaaat atgaggacat agcgtttaat caggtccaca
     3961 gtggatactt gcttcccatg gcaggcagag gatgtggggt ggttcggctt cttgtgaagg
     4021 tgagaaacta taatggaacc gaaagctttg taaatgtatt tcctcgagaa gtacatggtt
     4081 ccttagtgat aacacctcct gcgatgtcgc gagacttaaa atattcttga cgttaaaaca
     4141 cttaggtgta agatgcgatt attttggata aaatgttact ctggccaagg gaactcttat
     4201 tcaagtgatt tcatggattc aaatggcatg tagaaacagt gcgcatcagc gtctacttct
     4261 aagtgacaca aaagtgtccc ctttccaagc tgtggtgtgc gcgggaggtt ttgacgactg
     4321 agaattgtgc aggtctcctt tcagtgcatg ctctgaagag actccttctc tgactgtgta
     4381 tgacattggt aaagaatagg tactatcact ttctcatttt aaacttgaaa ctgtgaataa
     4441 ggtaagagaa ttattttgaa taaataagct atttatttaa aataccttgg tagttcccac
     4501 ttgcattctt cacactgctg tgatttgatc tgcttgctta tgatatcaaa cctttacaaa
     4561 gtacatggct cctaattttc aaggcaaagg tttcccctac attcctgctc ctgggacatt
     4621 ctgctgtgcc ctgctgctct ggggatcttg tccagtgccc actgcatgtg gggccgtcaa
     4681 gctgtcacta acagttgcaa ggaagtccag catttgcacc aggcagactc ttgatatctg
     4741 gtatctggcc acagttacat ccccttccac accagcccca cttacagatg tgggtttctg
     4801 tcactggagc aagcaggtct ccattgcaac aaagcagatt attctctcac tatttgtcta
     4861 gttccttgtt tggtttgcat tgttgtcatt ggaacaaatt tgcacctgtt tacaagagtt
     4921 aatcattgca acccttaaaa cgttggtgaa actgtaaagc tttgagccag ctcctcagcc
     4981 tccttttagg acgcctgtgt ccttagccct gcagcaagtg tgcacacagt accacagccc
     5041 ttccttcctc cactggaggg ccctgtggaa caggcgaact catcaggatt cccgtgctgc
     5101 cctagaaaga ggctggagtg ttaggactac ttgtctccaa gcccctctcc ttagctgaaa
     5161 agccttctga taggaaaatg gattttaagc aaggaagtag aaattttggc tctttctctt
     5221 gtcatagcaa taacatgaaa atttctgcag gagaaataaa agatacttct caaatatgtt
     5281 gtaa
//
