LOCUS       NM_203508               1393 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus epididymal protein 3B (Eddm3b), mRNA.
ACCESSION   NM_203508 XM_127698
VERSION     NM_203508.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1393)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1393)
  AUTHORS   Sun,J., Lu,Y., Nozawa,K., Xu,Z., Morohoshi,A., Castaneda,J.M.,
            Noda,T., Miyata,H., Abbasi,F., Shawki,H.H., Takahashi,S.,
            Devlin,D.J., Yu,Z., Matzuk,R.M., Garcia,T.X., Matzuk,M.M. and
            Ikawa,M.
  TITLE     CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or
            epididymis-enriched genes individually dispensable for male
            reproductiondagger
  JOURNAL   Biol Reprod 103 (2), 183-194 (2020)
   PUBMED   32588039
REFERENCE   3  (bases 1 to 1393)
  AUTHORS   Grassmeyer,J., Mukherjee,M., deRiso,J., Hettinger,C., Bailey,M.,
            Sinha,S., Visvader,J.E., Zhao,H., Fogarty,E. and Surendran,K.
  TITLE     Elf5 is a principal cell lineage specific transcription factor in
            the kidney that contributes to Aqp2 and Avpr2 gene expression
  JOURNAL   Dev Biol 424 (1), 77-89 (2017)
   PUBMED   28215940
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163664.3.
            
            On Jan 23, 2019 this sequence version replaced NM_203508.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC031737.1, AK136724.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-158               AC163664.3         116512-116669       c
            159-1393            AC163664.3         113307-114541       c
FEATURES             Location/Qualifiers
     source          1..1393
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 26.38 cM"
     gene            1..1393
                     /gene="Eddm3b"
                     /gene_synonym="Fam12; Gm75"
                     /note="epididymal protein 3B"
                     /db_xref="GeneID:219026"
                     /db_xref="MGI:MGI:2684921"
     exon            1..158
                     /gene="Eddm3b"
                     /gene_synonym="Fam12; Gm75"
                     /inference="alignment:Splign:2.1.0"
     exon            159..1393
                     /gene="Eddm3b"
                     /gene_synonym="Fam12; Gm75"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..608
                     /gene="Eddm3b"
                     /gene_synonym="Fam12; Gm75"
                     /note="epididymal secretory protein 3; family with
                     sequence similarity 12"
                     /codon_start=1
                     /product="epididymal secretory protein E3-beta precursor"
                     /protein_id="NP_987104.1"
                     /db_xref="CCDS:CCDS27036.1"
                     /db_xref="GeneID:219026"
                     /db_xref="MGI:MGI:2684921"
                     /translation="MSLVPALMSSLKAWALLLLLLCLQHSLLAQSTSRRQFMEHHHLS
                     PNKMFSDYNCDVLMTDKAVKPKLSHMFVYMTWYKVEHICIGSNWRDRYKNMYIWAQTP
                     IKVLRCQWESLKNRYTERRSYSYVQFHCNADGYVDSIEDIKALEPIL"
ORIGIN      
        1 ggtgtagtcc tggctgtcct ggaactcagg tcattctttt tactgctgtg gactttcccc
       61 ggaaagtttc ttaggagctc tgaaaaggac tcagactcta cccttcagat ctccatacct
      121 ctgtacccac tgtaaccagc gacgggtgca ctgattagat gtccttggtg cctgctctga
      181 tgtcctctct aaaagcctgg gccctgcttc tgctcctgct gtgcctgcag catagcctac
      241 ttgcccaaag cacttccagg aggcagttca tggaacacca tcacctgagt ccaaacaaaa
      301 tgttcagtga ctataactgt gatgtcctca tgacagataa agccgtgaaa cccaagctct
      361 cacacatgtt tgtttatatg acatggtaca aagttgaaca tatatgcatt ggtagcaact
      421 ggagagatcg ctacaaaaat atgtatattt gggcccagac tcccattaag gtcctcaggt
      481 gccagtggga gagtttgaaa aatagatata cagagagaag gagttacagc tacgttcagt
      541 tccattgcaa tgctgatggg tatgtcgaca gcatagagga cataaaggct ctagagccca
      601 tcctgtagaa agtctcatca cctctggatg gttctgaaag agcagtgaat agttctcaag
      661 tgtcaacctc cttcacccac ccctcactct cccacccacc cccaatcctc cacccttcac
      721 ccctaccctc caccccactt acccttcacc ctccaccccc tgcttacaat agttactgtt
      781 acttctgctt tgcaattgtc tgtcagtatt ttgcaatcaa tcacattgat tcttggtatt
      841 acaatcgtgt ttatgggttg tctgcctgca ataacattct tcccttgttt acctactttt
      901 attcccattt ttcatgactc ggctctctgc tactgtgaca aaatgtttga gagaaagcat
      961 tcaaaggagg gtttatttgc ctcctaatct ctgggctggt ctgtagtctg ctggctctgt
     1021 tgtcctcagg gaagagttag gcagagcatt gtggtgggga aatgtggaaa gtagacagag
     1081 aaggaaggag aagagtatag ggacaagata agacaatggc agctccagtg acatacctcc
     1141 tctaggtggg ccttcagatc cactcagcta tgaattcatc aatggattaa tccactgcca
     1201 aaataattac agctttcatg acccaactgt caaataaacc ttcaacacag gagcccatgg
     1261 gaggacattg gacagccaaa ccatgccagc atcttctctt gacttatcca ggatttttgc
     1321 tgatatcatc atctttatgc ctattcaaac taaatgatct tcccttccca gaataaattg
     1381 ttattccatt gtg
//
