LOCUS       NM_001410071            3453 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus enhancer of mRNA decapping 3 (Edc3), transcript
            variant 2, mRNA.
ACCESSION   NM_001410071 XM_011242760
VERSION     NM_001410071.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3453)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3453)
  AUTHORS   Zhou,Z., Shirakawa,T., Ohbo,K., Sada,A., Wu,Q., Hasegawa,K.,
            Saba,R. and Saga,Y.
  TITLE     RNA Binding Protein Nanos2 Organizes Post-transcriptional Buffering
            System to Retain Primitive State of Mouse Spermatogonial Stem Cells
  JOURNAL   Dev Cell 34 (1), 96-107 (2015)
   PUBMED   26120033
REFERENCE   3  (bases 1 to 3453)
  AUTHORS   Larance,M., Rowland,A.F., Hoehn,K.L., Humphreys,D.T., Preiss,T.,
            Guilhaus,M. and James,D.E.
  TITLE     Global phosphoproteomics identifies a major role for AKT and 14-3-3
            in regulating EDC3
  JOURNAL   Mol Cell Proteomics 9 (4), 682-694 (2010)
   PUBMED   20051463
  REMARK    GeneRIF: Induction of 14-3-3 binding to EDC3 causes morphological
            changes in processing body structures, inhibition of
            microRNA-mediated mRNA post-transcriptional regulation, and
            alterations in the protein- protein interactions of EDC3.
REFERENCE   4  (bases 1 to 3453)
  AUTHORS   McDaniel,A.H., Li,X., Tordoff,M.G., Bachmanov,A.A. and Reed,D.R.
  TITLE     A locus on mouse Chromosome 9 (Adip5) affects the relative weight
            of the gonadal but not retroperitoneal adipose depot
  JOURNAL   Mamm Genome 17 (11), 1078-1092 (2006)
   PUBMED   17103052
REFERENCE   5  (bases 1 to 3453)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   6  (bases 1 to 3453)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122515.5.
            
            On Jul 27, 2022 this sequence version replaced XM_011242760.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422600.436557.1,
                                           SRR13422598.724331.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849388, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               AC122515.5         74020-74164         c
            146-241             AC122515.5         70244-70339         c
            242-422             AC122515.5         69158-69338         c
            423-742             AC122515.5         66452-66771         c
            743-1078            AC122515.5         55198-55533         c
            1079-1232           AC122515.5         42676-42829         c
            1233-1450           AC122515.5         37917-38134         c
            1451-3453           AC122515.5         32556-34558         c
FEATURES             Location/Qualifiers
     source          1..3453
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 31.37 cM"
     gene            1..3453
                     /gene="Edc3"
                     /gene_synonym="Lsm16; Yjdc"
                     /note="enhancer of mRNA decapping 3"
                     /db_xref="GeneID:353190"
                     /db_xref="MGI:MGI:2142951"
     exon            1..145
                     /gene="Edc3"
                     /gene_synonym="Lsm16; Yjdc"
                     /inference="alignment:Splign:2.1.0"
     exon            146..241
                     /gene="Edc3"
                     /gene_synonym="Lsm16; Yjdc"
                     /inference="alignment:Splign:2.1.0"
     exon            242..422
                     /gene="Edc3"
                     /gene_synonym="Lsm16; Yjdc"
                     /inference="alignment:Splign:2.1.0"
     exon            423..742
                     /gene="Edc3"
                     /gene_synonym="Lsm16; Yjdc"
                     /inference="alignment:Splign:2.1.0"
     exon            743..1078
                     /gene="Edc3"
                     /gene_synonym="Lsm16; Yjdc"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1232
                     /gene="Edc3"
                     /gene_synonym="Lsm16; Yjdc"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..1450
                     /gene="Edc3"
                     /gene_synonym="Lsm16; Yjdc"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..3453
                     /gene="Edc3"
                     /gene_synonym="Lsm16; Yjdc"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3423..3428
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Edc3"
                     /gene_synonym="Lsm16; Yjdc"
                     /note="hexamer: AATAAA"
     polyA_site      3453
                     /gene="Edc3"
                     /gene_synonym="Lsm16; Yjdc"
                     /note="major polyA site"
ORIGIN      
        1 aggccgagac gcgggggcgt ttccggcgga ggtggcggct gcttctgtgt ctgtggcggt
       61 gggcgtgaag cccctcggtg gggttttggc gagcgaggtc gtcttggtgt gctgtgcagc
      121 gcaggcgggg gcaggcggcg gggagtacct aaggagtcca gaagagggcg tcagactctc
      181 tggaactgga gtcacccaca tgtgtgtgat gggaatggaa ccaggatcct atagaagagc
      241 gtgattcaca tctgagacat ggctatggat tggctaggca gtattgtgtc catcaactgt
      301 ggagatagcc tgggcgtcta ccagggaaga gtatcagcag tggatcaggt cagccagacc
      361 atttctctta ctcggccctt ccacaatggg gtgaagtgtc ttgtaccaga agtcaccttt
      421 cgggcaggtg atattacaga attaaaaatt ttggagatac caggtcctgg agacaaccag
      481 caggttggag accttcatca gacagaatta ggcccttctg gtgttgggta ccaaatgagt
      541 atcagtcaga atggaacagg caaggtggtc aagaagccag cctcttccag tagtgcccct
      601 cagagcatcc ctaagaggac agatgtgaag agccaggatg ttgccatttc tcctcagcag
      661 cagcagtgct caaagagtta tgtggacagg cacatggaat ctttgagtca gtccaaaagc
      721 ttccgtcgtc ggcacaactc ctggtcatct agtagcaggc acccaaacca ggcaactcca
      781 aagaaaagtg gtttaaaaaa tggccagatg aagaataaag atgacgagtg ctttggagac
      841 gatatcgagg agctcccaga cacggacttt gactttgagg ggaacctggc cctgtttgac
      901 aaggcggctg tgtttgagga gatcgacact tacgagagga gaagtggctc ccgttctcgg
      961 ggtgtcccaa atgaacgtcc tgctaggtac cgccatgatg aaaacatcct ggaatcggag
     1021 ccgattgtgt accgtaggat cacagtacca cacagcgtga gcaaggagtt ctgcacggac
     1081 tctggcctgg tagtcccaag tgtttcctat gagctacata aaaagctgtt gtctgtggct
     1141 gagaagcatg ggctgacctt agagcggaga cttgagatga ctggtgtgtg tgccagtcag
     1201 atggcgctga ctctccttgg aggacccaac aggttgaatc ctaagaatgt ccaccagagg
     1261 cccacagtag ctctcttgtg cggcccccat gtgaaggggg ctcagggcat cagttgtggg
     1321 aggcacctcg ccaaccatga tgtgcaagtc atcctcttcc tgcccaactt tgtcaagatg
     1381 ctggagtcta ttaccaacga gctgtctctc ttcagcaaga cccaagggca gcaagtgtct
     1441 agcctaagag atctccctgc tagccctgtg gacctggtta tcaactgcct ggattgtcct
     1501 gagaatgcct tcctgcggga tcagccctgg tacaaggcag ctgtggcctg ggccaaccag
     1561 aaccgggcac cagtgctcag catagaccct cctgtgcatg aagttgaaca gggcattgat
     1621 gccaaatggt ccctggcact gggcctgcct ctgccactcg gggagcacgc aggccgagtc
     1681 tatttgtgtg acattggcat tccccagcaa gtcttccagg aggttggcat caactaccat
     1741 tcaccttttg gctgcaaatt tgtcattccc ctacactctg cctagagggg ctctgggcag
     1801 ctggaccctg tattccctgc actcctgcag ccaaacccac tatgggacgc cttaaggatg
     1861 tgaggctttg tggaccttgt agactatctc ttgggtttat ttcttctgtg agagaacaaa
     1921 acatacttca aacttgcctg ccaccttccc ttaaccaggg aaggctttcc cactggcatg
     1981 tatgtcaggg gtggaccagt ggctccaggc atctttcaat cctaccctgc ctccattaaa
     2041 ctggagcttt gtttacagac ataggcagct ctaagactgt gtcaggttta cagccactgg
     2101 gtgtgggctg gcacattgcg gggatgggcc agaacctgtt agggcctcca gccactctta
     2161 tttcagaagg ctttatgtct cctatgcttc ctttggccct gcaaccaggc agcccacttg
     2221 tcctgtaatc attagatcag gctgcatggc agctatccag aagacaaacc cgtgtgtgtc
     2281 tctgcttccc cccaaggcta ccagagtttg tttggaaact ttggaccctc ctcagatgtt
     2341 ccaattttat gttgggactt ttcctgagga gtgtgtcagg atgactgtgg taaagacttt
     2401 ggactggctg ctctgctgtc atcagcagtt ttgtgcctgt caagctacaa tgcccatctc
     2461 ctagttagga accagacctt catgatacag cttttcagta ttggggagac cttggaggag
     2521 cttggtgctt ctaccatcat ttcctacctc cttgtccata aatacgcctc cgtctgcccc
     2581 tctgtctctg gaaatggccg ttttcagcta tcccaggaca ggttacatgt cccccatcct
     2641 gccatggctt cactccagtt cttatgttta ggctttaatc ctttatagtt gccctcctca
     2701 ggtgtatagt tggaactagt ggcctgtctc aaacatgcca aaaatgagcc cagttctaga
     2761 tgacagtagt gggattcagc catgcgaaca tcgcactgct caggtcctac ctagggcatt
     2821 atcctcagga tcttcctagg cttgggtcct tcaggttagg agggtaggac catgcctgga
     2881 gcctcagcag agacctttgt aaaggtcttg tactttgaag ctttctactg tgcccagcac
     2941 tggttgaggg gtataggtgg acaggcaggt gggcttgcta aaatgtttgg gtacagagta
     3001 aaccctagta ccatgaattt ttcaggctgc ttccttgtag gaacagatga tgatagcctt
     3061 tccgtctctt ctcttcagtt atctccagct ccaggaaaga ggccagagga ctgggagcct
     3121 cagctgcacg acagaacttt agcttttaag ctggacctct ttttctaaag gcggggttac
     3181 aattgggaca gcaggcagcc actacaggct actagacaca cataagatgg tagaactctg
     3241 gtcctgaaga tggttagcat tcggcagttc tccctgctct tggcctggac ctgcctagag
     3301 ttgaaagtgt gttactccta cctgcagctc tttttggaag tttctgctca atggctggtt
     3361 tcagtcaggt ggtcatattt gtcactaatg catgcagctc ttgggaaacc caaagccagc
     3421 acaataaagt gacagaaacc tgtgctatct aaa
//
