LOCUS       NM_133643               8103 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus EDAR associated via death domain (Edaradd), mRNA.
ACCESSION   NM_133643 NM_175746
VERSION     NM_133643.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8103)
  AUTHORS   Wang,Q., Zeng,S., Liang,Y., Zhou,R. and Wang,D.
  TITLE     ASH2L Mediates Epidermal Differentiation and Hair Follicle
            Morphogenesis through H3K4me3 Modification
  JOURNAL   J Invest Dermatol 144 (11), 2406-2416 (2024)
   PUBMED   38582368
REFERENCE   2  (bases 1 to 8103)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 8103)
  AUTHORS   Fan,X., Wang,D., Burgmaier,J.E., Teng,Y., Romano,R.A., Sinha,S. and
            Yi,R.
  TITLE     Single Cell and Open Chromatin Analysis Reveals Molecular Origin of
            Epidermal Cells of the Skin
  JOURNAL   Dev Cell 47 (1), 21-37 (2018)
   PUBMED   30220568
  REMARK    Erratum:[Dev Cell. 2018 Oct 8;47(1):133. doi:
            10.1016/j.devcel.2018.09.019.. PMID: 30300587]
REFERENCE   4  (bases 1 to 8103)
  AUTHORS   Azar,A., Piccinelli,C., Brown,H., Headon,D. and Cheeseman,M.
  TITLE     Ectodysplasin signalling deficiency in mouse models of hypohidrotic
            ectodermal dysplasia leads to middle ear and nasal pathology
  JOURNAL   Hum Mol Genet 25 (16), 3564-3577 (2016)
   PUBMED   27378689
  REMARK    GeneRIF: Mouse models with HED also carry Eda, Edar or Edaradd
            mutations and have defects that map to the same structures.We
            report that otitis media, rhinitis and nasopharyngitis occur at
            high frequency in Eda and Edar mutant mice and explore the
            pathogenic mechanisms related to glandular function, microbial and
            immune parameters in these lines
REFERENCE   5  (bases 1 to 8103)
  AUTHORS   Keen,C.L. and Hurley,L.S.
  TITLE     Developmental patterns of copper and zinc concentrations in mouse
            liver and brain: evidence that the gene crinkled (cr) is associated
            with an abnormality in copper metabolism
  JOURNAL   J Inorg Biochem 11 (3), 269-277 (1979)
   PUBMED   512661
REFERENCE   6  (bases 1 to 8103)
  AUTHORS   Keen,C.L. and Hurley,L.S.
  TITLE     Superoxide dismutase activity in the crinkled mutant mouse:
            ameliorative effects of dietary copper supplementation
  JOURNAL   Proc Soc Exp Biol Med 162 (1), 152-156 (1979)
   PUBMED   504225
REFERENCE   7  (bases 1 to 8103)
  AUTHORS   Sofaer,J.A.
  TITLE     Additive effects of the genes tabby and crinkled on tooth size in
            the mouse
  JOURNAL   Genet Res 33 (2), 169-174 (1979)
   PUBMED   478295
REFERENCE   8  (bases 1 to 8103)
  AUTHORS   Mayer,T.C., Miller,C.K. and Green,M.C.
  TITLE     Site of action of the crinkled (cr) locus in the mouse
  JOURNAL   Dev Biol 55 (2), 397-401 (1977)
   PUBMED   320066
REFERENCE   9  (bases 1 to 8103)
  AUTHORS   Hurley,L.S.
  TITLE     Interaction of genes and metals in development
  JOURNAL   Fed Proc 35 (11), 2271-2275 (1976)
   PUBMED   133823
  REMARK    Review article
REFERENCE   10 (bases 1 to 8103)
  AUTHORS   FALCONER,D.S., FRASER,A.S. and KING,J.W.
  TITLE     The genetics and development of 'crinkled', a new mutant in the
            house mouse
  JOURNAL   J Genet 50 (2), 324-344 (1951)
   PUBMED   24539712
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY766445.1, AK041545.1, BC030683.1, CT954220.7 and AC154221.3.
            
            On Mar 29, 2011 this sequence version replaced NM_133643.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK148351.1, AK075786.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849375,
                                           SAMN00849377 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                BY766445.1         2-68
            68-424              AK041545.1         2-358
            425-1733            BC030683.1         1-1309
            1734-3997           CT954220.7         7600-9863           c
            3998-8103           AC154221.3         1-4106
FEATURES             Location/Qualifiers
     source          1..8103
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 4.77 cM"
     gene            1..8103
                     /gene="Edaradd"
                     /gene_synonym="1810032E07Rik; 5830469M23Rik; A630043P06;
                     cr"
                     /note="EDAR associated via death domain"
                     /db_xref="GeneID:171211"
                     /db_xref="MGI:MGI:1931001"
     exon            1..533
                     /gene="Edaradd"
                     /gene_synonym="1810032E07Rik; 5830469M23Rik; A630043P06;
                     cr"
                     /inference="alignment:Splign:2.1.0"
     CDS             503..1129
                     /gene="Edaradd"
                     /gene_synonym="1810032E07Rik; 5830469M23Rik; A630043P06;
                     cr"
                     /note="ectodysplasin-A receptor-associated adapter
                     protein; EDAR-associated death domain protein; crinkled;
                     EDAR (ectodysplasin-A receptor)-associated death domain"
                     /codon_start=1
                     /product="ectodysplasin-A receptor-associated adapter
                     protein isoform 1"
                     /protein_id="NP_598398.3"
                     /db_xref="CCDS:CCDS36593.1"
                     /db_xref="GeneID:171211"
                     /db_xref="MGI:MGI:1931001"
                     /translation="MASPDDPLRSDHMAKEPVEDTDPSTLSFAMSDKYPIQDTGLPKA
                     KECDTVNSNCPPNSDDQPQGEENDFPDSTKDPLSGVSRNQPCKDGKGSCSCPSCSPRA
                     PTISDLLNDQDLLDTIRIKLDPCHPTVKNWRNFASKWGMPYDELCFLEQRPQSPTLEF
                     LFRNSQRTVGQLMELCRLYHRADVEKILRRWVDEEWPHRGHSDSSMHF"
     exon            534..592
                     /gene="Edaradd"
                     /gene_synonym="1810032E07Rik; 5830469M23Rik; A630043P06;
                     cr"
                     /inference="alignment:Splign:2.1.0"
     exon            593..632
                     /gene="Edaradd"
                     /gene_synonym="1810032E07Rik; 5830469M23Rik; A630043P06;
                     cr"
                     /inference="alignment:Splign:2.1.0"
     exon            633..691
                     /gene="Edaradd"
                     /gene_synonym="1810032E07Rik; 5830469M23Rik; A630043P06;
                     cr"
                     /inference="alignment:Splign:2.1.0"
     exon            692..737
                     /gene="Edaradd"
                     /gene_synonym="1810032E07Rik; 5830469M23Rik; A630043P06;
                     cr"
                     /inference="alignment:Splign:2.1.0"
     exon            738..8103
                     /gene="Edaradd"
                     /gene_synonym="1810032E07Rik; 5830469M23Rik; A630043P06;
                     cr"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6658..6663
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Edaradd"
                     /gene_synonym="1810032E07Rik; 5830469M23Rik; A630043P06;
                     cr"
                     /note="hexamer: ATTAAA"
     polyA_site      6680
                     /gene="Edaradd"
                     /gene_synonym="1810032E07Rik; 5830469M23Rik; A630043P06;
                     cr"
                     /note="major polyA site"
ORIGIN      
        1 gtctcagccc gggcctgtgc aaggagcacg ctgggagtgc tttggtgtcc cagctgagga
       61 cgagattagg agccgggaaa gccacccgcg cgtgcggcag ccaggggaag gctagctgaa
      121 aggctctccc agttgcgatc gcgtgggacc tccgtggtaa gaccagggtt ctacgcccta
      181 ggtaccagca gggcaagtgc tccgggggcc cctcggtgtc ctctcgtgcc caaccgcaac
      241 ccacggaatc ctctccagag ttctggagag actcgcgccg ggaaggggct ttgctaattg
      301 caggaagtga gcacgaggaa gaagtggcag agatcaagaa gaggaaaggg aggaggagga
      361 gcagcagcag cagcagggca gagcgcagac agagtcgcgc attaccacgc aagaggttgg
      421 gtccctgcga tcctgctgtt ctcaggggtc ctagagactg tccacccctg ctcggacact
      481 catctgtcct ctcctggtct tcatggcttc tccggacgac cctctgcgct cagatcacat
      541 ggcaaaggag ccagtggagg acacggaccc cagcacttta tcctttgcca tgtcagacaa
      601 gtatcccatt caagacaccg gcctccctaa agctaaagag tgtgatacag tcaattccaa
      661 ctgtccacca aattctgatg accaacctca gggagaagaa aatgactttc cagacagcac
      721 caaagatccc ctttcaggtg tcagcagaaa ccagccctgt aaggacggga agggcagctg
      781 ctcttgccct tcctgctccc cccgggcccc caccatcagc gacttgctca acgatcagga
      841 cttgctagat acgatcagga taaagctgga tccatgtcac ccaaccgtga agaactggag
      901 gaattttgcc agcaaatggg gcatgcccta tgatgaactg tgcttcctgg aacagaggcc
      961 ccagagcccc acgctggagt tcttattccg aaacagccag aggactgtgg gccaactgat
     1021 ggagctctgc cggctgtacc acagggccga tgtggagaag atcctgcgca ggtgggtgga
     1081 tgaggagtgg ccccaccggg gacactccga cagctccatg cacttctaga atcccctctc
     1141 ctctggcatt ggccctactg ctcgttggac cagcatggct cctgcggaga gcgtacctgc
     1201 tcctaaggtt ttcaggataa ggtgtgggca gtggtcgtcc ccgaagctgg cagcttttgg
     1261 aaagacacgt tgtttggatg gcaggtatcc gtttcctttt gcacatttgt tttaatttaa
     1321 tatttgagcc tgggattggg gaagaatatt tggtaggtca cacagggcca aagcctgtgg
     1381 acagagacat gccaacatgg aaagaaaatg acaccctctt taaatactgc caaagattgc
     1441 agcgggatcc caaaatatca atgtctttgg acatgtccgc atacagaatc ccatacagaa
     1501 tctctgcagt cctggccaga ggatggcagg gagaagtcat cccggccggt tcactgtcac
     1561 tgtttctgtt gaaaaaggct caggagagca aaaggatact actgtataat gtggcccagg
     1621 tatatgggct cttttttttt taatcaaata cttttgtaat ctataggcta tcaatactgt
     1681 cattgaattt agcattttta aaagaaatac aaaatatatg gtttgtagga gaagagagtg
     1741 tcttgggagt ggcattgaca aagaatagtg ctcagttcgg cctttgggaa gctagggagg
     1801 tagctcagtg attacggtgc cctccacata aagcatggga ccagagtctg ggtccccaga
     1861 acccacataa gtgaggggag gctgtggtag cccacctgtg atcccagcac tcagaaggca
     1921 gaggtggcgg cgatcccaga gcaagctggc tagctacacc tggcacatgg atgaactctg
     1981 ggttcaactg agactctttc tccatgaaca atgtgcagag tgattgagga aaactttcaa
     2041 catcaacttt ggaagtctat atgcacacac atgtacatgc acatctgcat acatgtgcaa
     2101 caacaacaac aacaaacaca cacgcgcaca tcttttaaaa tgccctttgg gaaggctgag
     2161 gacatgggcc aatgagcgca cacataatag ccagacgtgg cagcatgtgc ctgtaactcc
     2221 agtactgggg agcaaggtcc aggaactccc tggccagcca gatagccaaa ttggcaaggt
     2281 ttttgttcag ggagagaccc tgtctcaaaa aaggaaagtg aagaataact aaggaagata
     2341 cctgagggac aacctttgac ctaaacacac acacacacat atacttgctt gttatgcatg
     2401 cctttaaaaa aaaaaaaaaa aagcagggcc aggactctac cactgagcga gctacacctg
     2461 cacctctgtt attaatgggt tttattttta tgagaaccca caaaaaaaaa aaaaaagctg
     2521 ggcatggtgg tttatacttt taactctggc taggagacag gtggatccct ggggctcctc
     2581 tgccagccag cctagcctat gtgctgagct acaagctgat gagagatcct gtctcaaaaa
     2641 accaaggagc aacatcagag ttgttctctg gcttccccat gcacatgtgc acgcaagctc
     2701 gcaggcccat gtacatgtgc accaattaaa gtaaacagaa aggaagaatg tatactggct
     2761 gtatagcaca gagatagtaa gaggaacgca aaagaaggtg attttctaaa ccactttttt
     2821 tttctcataa cagttagatt tccccttagg cggttggtag gtaaagccag cttcccacac
     2881 agcgtgaact ccaatcaaca acgtctacag tgagacttgc ccatcagttc tggttcactg
     2941 ttaatcacac cagcgtccac tttattgcca gatatattta aagtgggagc tgatgattaa
     3001 atgcagacgt cctagtgttt tttagatgta tttgtatgaa tgttttccct gtgtgcatgg
     3061 tacctgcagt ggttgaaagg cgtcggatcc cctagaactg gagttgcaaa tgtctgtcca
     3121 tcaatctcca tgtgggtgct gggaacacat ctgcaagagc agctagtgca cccaacggca
     3181 gagcccgtct ccctagcccc tagacgcaga tatttttata agtagcttct caggaaagtc
     3241 agatgttgtg agcatcatga gcgtgatcta ggcttctagc agaacctgtg ggcatgttgt
     3301 ggggagctct aaacattgcg cagatgtgat tggttgccta ctttctcatt aagctctcca
     3361 tggcgtgatc tggctggttt tcacagggtc tcctagccca aggtgctctc actctcattc
     3421 tgtagcagag gatggcccag aatttccgat cgcctgcttc tgccttccaa gtgctgggcc
     3481 accacacgtg gtttagctct cacttcttag agcagaggcg actgtaggga aacgagaggg
     3541 gctttggaaa tcactttgca ggaaggaact cagaaggtga ggctcagaga tagaggaatg
     3601 atggagcatt gggaaatgcc agccctagct ttccaatgta tgccagaact tgagttccgt
     3661 acattacaaa catccagagt gagtactgct catgactggc ctggggtagc caatcctttc
     3721 acccatcgct ttcacaggaa gtgtttcaca ggaagtaagt gtttcacagg aagtgtttca
     3781 caggaagtgt tgccagtact tcagcctcta cgcaactggt caggatgcag ctccagaaca
     3841 cagctgtgct tgtaagtgtt cactgaattc accttccggg cattgggtca aaactgtgaa
     3901 gcggggctag ggggatggct cagcacttaa gaacacttgc tgctcttgag ctaagtttca
     3961 agtacccaca tggggtgagt catgactagc tcctggggat ccgacaccct cttctagtct
     4021 ccaagggcac tcgtacatac atggcataca cttacacaca cacacacaca cacacgcaaa
     4081 tccctaaaag aatgtcaagc ttggcctgag aatgcagctc agttgttaga gtccttgcct
     4141 agtgagccaa agtttggtcc ccagcattgc ataaaccact gtgatgatac acgtcccact
     4201 tccagcactc gggggtagaa gtagaggatc agaaattcaa agttatcctt agctacaacg
     4261 tgagtttgag gccagccttc catatatgag accctgcttc aaaaagaaaa cagaatgtca
     4321 tgcaagccat gtgtgctgct ccgtgactgt caccccagca tttaccttgt gagcgtttct
     4381 aattataata ggatcgtgaa atcagcagag aagtactgaa agatgtccgg aaattaactc
     4441 tgactataag tgtaagatga cttggatctg tgttgtacaa agaaagccaa ggattattct
     4501 cagctacagt acaaaccagc ttattgaaag gtagcttata gccagtgggt tctactgaaa
     4561 catagataga taccctggaa cttcacagag gtgaggccag gggggaggag gtcactttat
     4621 gaccaactga ttaattattg aaagcttagt catcactttt taaatattcg atcattttta
     4681 atcacatgtc tctgtgtgag gtgtgcacgt gagtataggt gtttgtagag acctgaggtg
     4741 tcagattccc ccagagacgg agttgctaga catgggtgtt gggaactgaa ctcatgtcct
     4801 ctataagagt agtgtgagat cttacctgat gagccatttc tccaccccat catcattaac
     4861 ccttaagagc tttctgtcct ggacacccat attaaagtga actgctcggg aatgaggttg
     4921 gtttcctatt aaaatgttga aatctgctta gctatgtttc ccaaagtatt tttctttaag
     4981 agaaatttcc atctgtaaag gtctatgatg aggccatata taggatgcat tttatttggg
     5041 tgcagtagtg gagagtcaaa cgaaagggag ggactcaaag tcacactgga cagccgtata
     5101 cacagggaca gatgacacac tcctggggac ccataccaga gtgtcgggca aaaacacggc
     5161 atgcaatatt agcacagtga ggttttttaa ttagttaggg cttgaagctg tgctaggatg
     5221 tccaacctgt gcctcttaaa acaaacaaac aaacaaacaa acacctctgt acaaagtagc
     5281 cacctacttg tgtagcactt tgtaataata cagaaaatct ggccctcccg aacagtaatt
     5341 tatgtgatgc tgccccctgc tggaggatac agagtctggc ttggttaggc gccttccaag
     5401 gaggccccac taagacagaa agagaaaggg tatgttttct ctgtgacttg gcagacgaag
     5461 gcactataca gtgatggagg ctcatgtctc caggatgtgc ccagcacagt ggcctggtac
     5521 tcatctgtca gcactgatgc acttgcctcc tcgggtctct tgggtctctt cctctcccag
     5581 ttaagcaccc aaggatgctg ggatgcagca gtctcattta cactacaaaa agacgtgctt
     5641 ctaaagacag gattaacaac agaggccaaa cagatttttc tcttctggcc tctcctatgt
     5701 aaggcagtta agcagatctc atttggtttt gagcaaagac tttcccccag gtcttttttt
     5761 tttttttttt ttttaatcaa ccctattgtc cctgctttat aatttccctc ccatttgaag
     5821 ccgtgatatt gctgtctaca ccacttgctc agagcgagct gtatgcatat ctcaaatcgt
     5881 cttcctcccc cggccaacag tattcccctc tctgagctgg cagcaaacat ctgcttcgtg
     5941 ttgccacgtg tacacacaga aacaacaatg ccatcgatgt agcaatgcca aaccactctg
     6001 ccccgggtgc tacaaaacca aaggcagaga gaggcacaca cctccggaag cacactgaga
     6061 gatatttgca gttttgtcgc ctgcctggga ctcagacccc accctgggac tcctgggccc
     6121 ttggttatag atgcacaagg aaggggggaa tcttagcttt gctgtgttta gagagaatca
     6181 aagccaagat gctgggccga gtgctggggc tattgaagtc tcagcatcag tggatggagc
     6241 accagtgggt tcccaagacc tagacttgaa ggaccttggt ggaacagggt gtgcttcctt
     6301 ccggaggctg tggagggcta tggctctggg agggaatccc tgggtggtca cgtggactga
     6361 agaccctgga gtggtcagtg atacaactgg aaatgaaatg atggaactgc ccagatctct
     6421 tggacatgga agaggatgtt gcattttgtg tgaccgtcca gtctgtcctc tgcagcatcc
     6481 ctctgggaac ttacgcagac atttcagcct gcgaaggcaa agcttccgaa agccctgctt
     6541 cctcggaatg ccatccgtac accttggtgc tatccttttg aaactgtcta cattttcacc
     6601 tcctctgtga ttctgttttt ggaaagattt tataactgta ataatgggtg ctacaacatt
     6661 aaagactgat gtcaactgca gttctagtgg gtgcctcatt ttcttgaaat gtatatgcat
     6721 ttctgggaag gggcgttttg catgtacgcg aatgcgtgta gaggcaggag gacacccttg
     6781 gatgtcaggc acacaaacat accattcaca gattttgaga caaggtctgc cattggccta
     6841 gaactcatga attacaccag gctagctggc catgagaccc aagaggtctt cctatgtctg
     6901 gctcctcagt gtgaaaataa caagtgttat ttgctcagca ttttcacata ggttgtgtgt
     6961 cctcatgctt gaataaaagg cactttcttg actgggccat cccctaatac ctactttgta
     7021 tggactctag catggtcatc agctcatagg tcctgtagcc catcatctat ttctgttact
     7081 tgagtactct gtggttttct gaaatgagtc ccagatgctg aagatgctga gacaaacagc
     7141 ccaaccattc actccaggag ctgtcgacag acagtcactg caggtaaggg ctgataagac
     7201 tagggaatgt gggcaaaggt ggtccaggaa taggcccaag atgcgctgag caggaggaaa
     7261 agcgagcagt tagccttccg agagggtctc cagtgtactg tgtctgtatg tgaagggtca
     7321 tttcactatt cctacctgct tctcccgacc cagtccatcc tctaggtatc tgtgggttgc
     7381 cctctctgac aggaacactt cagactcacc tgttccatga ctaatcctcg cagcttcgtg
     7441 acctgctgga gttttctgtg tcaatcatct accagcagct tcagcatcct taagactctt
     7501 cttcctggtc tatttccctc tttgggctgt ttttgttatc actgtctctg tgtatggggt
     7561 gtgtgtgtgt gtggtacata caagaacaca gatatacatg agagtacata gtatgggggt
     7621 atacatgcct gtggaagtta ctggccaatc tccagttctc cagcatctcc tctggtgcca
     7681 cccaccttga ttttttttga gacaggatct ctctctggct tggttctcag gttttggact
     7741 gaggtgactg gctagcaagc cacacacaca cacacacaca cacacacaca cggatgccca
     7801 tgtttgccta gagtcactag gatccccaca tctctccacg cagtgtatct agctgctctg
     7861 tgttggaaac tgcccctttc aattcacttc gctccacatc tcatctttca cgcacgcgac
     7921 tgctcgagcc acccagaatc aaaaccaaac aagttgttac ctgcttgaat tcctcgttct
     7981 gccatctcat ccaaacataa ccatctctgt cagtttaaac gaggagactc tttgtgactc
     8041 taccttgaaa ttatcatggc atttgaaaat agcattagca ataaagtctt atcatggcta
     8101 ctt
//
