LOCUS       NM_172381               8737 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus Ecm29 proteasome adaptor and scaffold (Ecpas),
            transcript variant 2, mRNA.
ACCESSION   NM_172381
VERSION     NM_172381.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8737)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8737)
  AUTHORS   Sato,B., Kim,J., Morohoshi,K., Kang,W., Miyado,K., Tsuruta,F.,
            Kawano,N. and Chiba,T.
  TITLE     Proteasome-Associated Proteins, PA200 and ECPAS, Are Essential for
            Murine Spermatogenesis
  JOURNAL   Biomolecules 13 (4), 586 (2023)
   PUBMED   37189334
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8737)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8737)
  AUTHORS   Lee,M., Liu,Y.C., Chen,C., Lu,C.H., Lu,S.T., Huang,T.N., Hsu,M.T.,
            Hsueh,Y.P. and Cheng,P.L.
  TITLE     Ecm29-mediated proteasomal distribution modulates excitatory GABA
            responses in the developing brain
  JOURNAL   J Cell Biol 219 (2) (2020)
   PUBMED   31910261
  REMARK    GeneRIF: Ecm29-mediated proteasomal distribution modulates
            excitatory GABA responses in the developing brain.
REFERENCE   5  (bases 1 to 8737)
  AUTHORS   Gorbea,C., Goellner,G.M., Teter,K., Holmes,R.K. and Rechsteiner,M.
  TITLE     Characterization of mammalian Ecm29, a 26 S proteasome-associated
            protein that localizes to the nucleus and membrane vesicles
  JOURNAL   J Biol Chem 279 (52), 54849-54861 (2004)
   PUBMED   15496406
REFERENCE   6  (bases 1 to 8737)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK041579.1, BC058684.1, AK030369.1, AK054077.1, AL806535.7,
            BG079097.2, BE648557.1 and AW123771.1.
            
            On Sep 25, 2017 this sequence version replaced NM_172381.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058684.1, SRR10223969.4491.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-24                AK041579.1         3-26
            25-5925             BC058684.1         1-5901
            5926-6280           AK030369.1         1331-1685
            6281-7446           AK054077.1         1-1166
            7447-7447           AL806535.7         27034-27034
            7448-8351           AK054077.1         1168-2071
            8352-8355           BG079097.2         213-216
            8356-8721           BE648557.1         1-366
            8722-8737           AW123771.1         1-16                c
FEATURES             Location/Qualifiers
     source          1..8737
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 32.35 cM"
     gene            1..8737
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /note="Ecm29 proteasome adaptor and scaffold"
                     /db_xref="GeneID:230249"
                     /db_xref="MGI:MGI:2140220"
     exon            1..274
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     CDS             253..5775
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /note="isoform 2 is encoded by transcript variant 2;
                     proteasome-associated protein ECM29 homolog; ecm29;
                     proteasome adapter and scaffold protein ECM29"
                     /codon_start=1
                     /product="proteasome adapter and scaffold protein ECM29
                     isoform 2"
                     /protein_id="NP_759013.2"
                     /db_xref="CCDS:CCDS18214.1"
                     /db_xref="GeneID:230249"
                     /db_xref="MGI:MGI:2140220"
                     /translation="METGSDSDQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSST
                     QEGVRKKVMELLVHLNKRIKSRPKIQLPVETLLVQYQDPAAVSFVTNFTIIYVKMGYP
                     RLPVEKQCELAPTLLTAMEGKPQPQQDSLMHLLIPTLFHMKYPAESSKSASPFNLAEK
                     PKTVQLLLDFMLDVLLMPYGYVLNESQSRQNSSSSSQGSSSNSGGGSGIPQPPPGMSF
                     YAAKRVIGDNPWTPEQLEQCKLGIVKFIEAEQVPELEAVLHLVIASSDTRHSVATAAD
                     LELKSKQSLIDWNNPAIINKMYKVYLGDIPLKTKEGAVLKPELKRDPVSTRVKLKIVP
                     HLLRSRQAAETFPANIQVVYDGLFGTNTNSKLRTLSLQFVHHICLTCPEIKIKPLGPM
                     LLNGLTKLINEYKEDPKLLSMAYSAVGKLSSRMPHLFTKDIALVQQLFEALCKEEPET
                     RLAIQEALSMMVGAYSTLEGAQRTLMEALVASYLIKPEVQVRQVAVKFASTVFPSDHI
                     PSRYLLLLAAGDPREEVHGEAQRVLRCLPGRNKKESASKQMPSFPEMVYYIQEKASHR
                     MKTPVKYMTGTTVLPFNPAAFGEIVLYLRMCLAHSAGVVPTSQSLADMQDHAPAIGRY
                     IRALMSSSQATASSSNKSGETNPVQIYTGLLQQLLAGVGGLPVMYCLLEAVSVYPEKL
                     ATKFVDKTEWIKSLMSSSKEEMRELAALFYSVVVSTVSGIELKSMIEQLIKATKDNHS
                     PEVQHGSLLALGFTVGRYLAKKRVRMAEQHDLETDADLLPEQEEIIRSATETIGSFLD
                     STSPLLAIAACTALGEIGRNGPLPIPSEGSGFTKLHLVESLLNRIPSSKETNKMKERA
                     IQTLGYFPVGDGVFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAAIGTNSVAARDA
                     WLVTEEEYIPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLSLVRKLSTHR
                     EVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGNEQDQQELVSTLVETLMTG
                     KRVKHEVSGETVVFQGGGLGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNLANHHA
                     MWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVT
                     DKSMVDKYLKEILQDLIKNLTSNMWRVRESSCLALNDLLRGRPLDDVIDKLPEMWETL
                     FRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGAAGQRTIAVLLPCLLDKGMMSPV
                     TEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQEKD
                     VMDSARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLGTKGGCASVI
                     VSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQ
                     KLNGWYMEKDEPVYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSE
                     KEECNMWTEVWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASISKQ
                     TSSLVPPYLGMILSALMQGLAGRTWAGKEELLKAIACVVTACSTELEKSVPNQPTTNE
                     ILQAVLKECCKENLKYKIVAISCAADVLKATKEDRFQEFSDIVIPLIKKNSLESMGVR
                     TTKAEDENEKERELQLESLLGAFESLGKAWPRNPDTQRCYRQELCKLMCERLRLSTWK
                     VQLGVLQSMNAFFQGLMLLEEEHADPEALAEILLETCKSITYSLENKTYSSVRTEALS
                     VVELLLKKLEEAKQWESLTAECRGLLIESLATMETDNRPELQEKASVLKKTLESLE"
     exon            275..405
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            406..522
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            523..641
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            642..791
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            792..963
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1103
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            1104..1185
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1305
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            1306..1391
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            1392..1470
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            1471..1520
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            1521..1587
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            1588..1710
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            1711..1814
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            1815..1938
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            1939..2019
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            2020..2242
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            2243..2334
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            2335..2469
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            2470..2632
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            2633..2805
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            2806..2907
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            2908..3031
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            3032..3177
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            3178..3232
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            3233..3347
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            3348..3416
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            3417..3534
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            3535..3702
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            3703..3782
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            3783..3888
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            3889..3936
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            3937..4058
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            4059..4209
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            4210..4275
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            4276..4365
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            4366..4432
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            4433..4524
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            4525..4591
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            4592..4783
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            4784..4992
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            4993..5036
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            5037..5229
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            5230..5368
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            5369..5474
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            5475..5563
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            5564..5635
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     exon            5636..8722
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5909..5914
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /note="hexamer: AAGAAA"
     polyA_site      5926
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /note="major polyA site"
     regulatory      7023..7028
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /note="hexamer: AATAAA"
     polyA_site      7045
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
     regulatory      8693..8698
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
                     /note="hexamer: AATAAA"
     polyA_site      8713
                     /gene="Ecpas"
                     /gene_synonym="mKIAA0368"
ORIGIN      
        1 gattcgagcc ccgctctact tttccgagtc cgcgtctctt cctccgtccg ggcgcgtgtt
       61 cctccagctc cgaccaggcg gacgtgacag ccgcagacct ttaacgccac agcccggggc
      121 ggggaagctc tccgcggcag ccaggacagc ccggctccgc tcggccgcac gcaggctcct
      181 ccggagcggc cgcgcgtctc ctcgggcccg gcccgtcctc cacctcgctg ggtcgccgca
      241 gcatcccggg ctatggagac cggctccgac tcagatcagc tcgaacgggt ctttttacga
      301 cttggccatg ctgaaacaga tgaacagtta caaaatatta tatctaaatt ccttcctcct
      361 gttctgctca aactgtccag cacccaagaa ggagtacgga aaaaagtaat ggaactgctg
      421 gtccatctga ataaacgtat aaaaagccgc cccaaaatac agcttccagt agaaacacta
      481 ttggttcagt accaggaccc tgctgcagtt tcctttgtca cgaattttac tataatttat
      541 gttaagatgg gctatcctcg cctgccagtg gaaaaacaat gtgagctggc ccctacgctt
      601 cttactgcca tggaagggaa acctcagcca cagcaggata gcttaatgca tcttttaata
      661 ccaactcttt ttcacatgaa gtacccggct gaatcatcaa agtcagcttc tccttttaat
      721 cttgctgaga aaccaaagac tgtgcagctg ctcttggact ttatgctaga tgtccttctg
      781 atgccttacg gatatgtgtt aaatgaatcc cagagtcgcc aaaattcatc atcatcatca
      841 cagggttctt cttcaaacag tgggggaggt tctggaatcc cacagcctcc cccaggaatg
      901 agcttttatg cagctaaacg agttattggt gacaacccgt ggacacctga acagttggaa
      961 cagtgcaaat tgggtatagt gaagttcata gaagctgagc aggtgcctga acttgaagct
     1021 gttctccacc tggtgattgc ttctagtgac acacgccata gtgtcgcgac agccgcagac
     1081 ctggagttga aaagcaagca gagcttaatt gactggaata accctgccat cattaataag
     1141 atgtacaagg tgtaccttgg ggatatacca ctgaaaacaa aagagggagc agttctaaag
     1201 ccggagctga aaagagaccc agtcagtact agagtgaagt taaagattgt tcctcatctc
     1261 ctgcgctcta gacaagctgc tgaaacgttc ccagctaaca ttcaggtggt atatgatgga
     1321 ctttttggta caaatacaaa ctcaaagtta agaacactgt ccctgcaatt tgtacatcac
     1381 atttgtttaa cttgcccaga aatcaagatt aaaccactag gtcctatgct tttgaatggt
     1441 ctcactaagc taataaatga atataaagag gaccctaaac tactgtcaat ggcatattca
     1501 gctgttggga aactctccag tcgaatgccc catttattca ctaaggatat agctcttgtg
     1561 cagcagctct ttgaagccct ctgtaaggaa gaaccggaga ctcggcttgc tattcaggaa
     1621 gcgttatcta tgatggttgg agcttacagt accttagaag gagcacagag aactttaatg
     1681 gaggcacttg tagcttcata cttaataaag cctgaagttc aagttcggca agttgcagtg
     1741 aaatttgcca gcacggtgtt tccctcagat catatacctt ccagatactt gctcctacta
     1801 gctgcaggag acccacgaga agaagtccat ggtgaagcac agcgcgtatt acgatgtctt
     1861 cctggtagaa ataaaaagga aagtgcttct aagcagatgc catcttttcc agaaatggta
     1921 tattacattc aagaaaaggc ttcccatcga atgaaaactc cagtcaaata tatgaccgga
     1981 accacagtcc ttccatttaa tccagcagca tttggagaga tagttctgta cttgcgcatg
     2041 tgcctggctc atagtgcagg ggtggtaccc acttcccaga gtttggctga tatgcaagat
     2101 catgctccgg ctattggacg gtacatacgg gctttgatgt caagcagcca ggcgacagct
     2161 tcatcttcta ataagagtgg agaaaccaac cctgttcaga tctacactgg cctgcttcaa
     2221 cagctgctag cgggggttgg aggtttgcca gtcatgtact gtctattgga agctgtgtca
     2281 gtgtatccag aaaaattggc taccaaattt gtagacaaaa cagaatggat caagagtctg
     2341 atgagtagca gtaaagaaga aatgcgtgaa ttggcggctt tgttttattc tgtggttgtg
     2401 tctacagtgt ccggaattga gttaaagtca atgatagaac agctgataaa ggccacaaaa
     2461 gacaatcata gccctgaggt tcaacatgga tcgttgcttg ccttgggatt cactgttgga
     2521 agatacttgg ctaagaagag agtgaggatg gccgagcagc atgacctaga gacagatgct
     2581 gacctcttgc ctgagcaaga ggagatcatt cggagtgcta cagaaacaat aggttcattt
     2641 ttagacagta catcacctct gttagcaatt gctgcctgta cagccttggg tgaaatcggc
     2701 agaaatggtc ctcttccgat ccccagtgaa gggtctggat ttactaaact gcacctcgta
     2761 gaaagcttac tcaatagaat tccgtctagt aaagaaacaa acaagatgaa agaacgagca
     2821 atccaaacac tgggctattt tcctgttgga gatggggttt ttccccacca gaaactcctt
     2881 ttgcaaggtc tgatggattc tgtggaggcc aagcagattg agcttcagtt cactattggt
     2941 gaagccatta ccagtgctgc aataggaact aactctgtgg ctgcccgaga tgcctggctg
     3001 gtgactgaag aagaatatat acctcctgct ggtgccaaag tgaatgatgt tgtcccatgg
     3061 gttttagatg ttattttaaa taaacatatc atcagcccca acccacatgt caggcaagca
     3121 gcctgcatct ggcttctttc tcttgtgaga aaactaagta cccacagaga agtgaagtcc
     3181 catcttaaag aaattcagag cgcatttgtt tcagttctgt cagaaaatga tgaactcagc
     3241 caagatgttg cctcaaaggg gcttgggttg gtttatgagc tgggcaatga acaagatcaa
     3301 caagaattgg tgtctacact tgtagaaaca cttatgactg gcaaaagagt caaacatgaa
     3361 gtttctggag agacagtggt atttcaaggg ggtggccttg gcaaaacacc tgatggtcag
     3421 ggcctttcta cttacaagga gctttgctct ctggcaagtg atctcagtca gccagatctg
     3481 gtatataaat ttatgaatct ggcaaatcat catgcaatgt ggaactccag gaagggtgct
     3541 gcttttggtt ttaatgtaat tgctaccaga gctggagaac aactggctcc ttttctgcct
     3601 caactagttc ctcgccttta tcgataccag tttgatccca accttggaat tcgacaagct
     3661 atgacaagca tttggaatgc attggtcact gacaagtcaa tggtggataa atatttgaag
     3721 gaaattcttc aagatttgat taaaaacctt accagcaaca tgtggagagt tcgagaatcc
     3781 agctgtttag ctctgaatga tttattgaga ggaagacctt tagatgacgt cattgacaaa
     3841 cttccagaaa tgtgggaaac actttttaga gtacaagatg atattaagga gtctgtacgg
     3901 aaggcagcag aactggctct gaaaactctg agcaaggttt gtgtgaaaat gtgtgaccct
     3961 gccaaaggag cagctggcca gagaaccatt gctgtcctcc tgccctgcct tctggacaaa
     4021 ggaatgatga gtcctgtgac ggaagtccga gccctcagca ttaacactct tgtgaagatc
     4081 agcaaaagtg caggagccat gttgaaacca cacgcaccca aactcatacc agcactctta
     4141 gagtccttaa gtgtgttgga gcctcaagtt ctcaattatt tgagtctccg ggctacagaa
     4201 caagaaaagg atgtaatgga cagtgctcga ctcagtgctg ccaaatcctc tcccatgatg
     4261 gagacaatca acatgtgcct gcaatatctt gatgtttcgg tgctaggtga actagttcct
     4321 aggctatgtg agctgatcag aagtggtgta ggtcttggga ctaagggggg ctgtgccagt
     4381 gtcatcgtgt ctttaactac tcagtgtccc caggacctga caccttactc aggtaaactt
     4441 atgagtgctt tgcttagtgg tctgacagat cggaacagtg taattcagaa atcctgtgca
     4501 tttgccatgg gccatttagt tcggacttca cgggatagca gcactgagaa actgctacag
     4561 aagctcaatg gctggtacat ggagaaagat gaacctgtct ataagacgtc ttgtgctttg
     4621 acaattcatg caattggaag atacagccca gatgtattga agaaccatgc taaagaagtt
     4681 ctgcccttag catttctagg catgcatgaa attgctgatg aggagaaatc tgaaaaagaa
     4741 gagtgtaata tgtggactga agtgtggcag gaaaatgtac ctggctcctt tggaggtatt
     4801 cgattgtacc tgcaggaatt gattactatt acccagaagg ctttacaatc acaatcttgg
     4861 aaaatgaaag cccagggtgc aattgctatg gcatcaattt caaaacaaac aagctctctt
     4921 gtacctcctt acctggggat gatcctgagt gcattgatgc aaggcctggc tggaagaaca
     4981 tgggcaggaa aggaagaact attgaaagcc attgcctgtg tagtgacggc ttgcagtaca
     5041 gagttggaaa agtctgtgcc caatcaaccc accacaaatg aaattcttca ggctgtcttg
     5101 aaggagtgtt gcaaagagaa tctcaaatat aagattgttg caatcagctg tgcagctgat
     5161 gttttgaaag ccaccaaaga agacagattc caggagtttt ctgacattgt catacccctc
     5221 atcaagaaga actcacttga aagtatggga gtccgtacca ccaaagctga agatgaaaat
     5281 gagaaggaaa gagagctgca gctggagtct ctactgggcg cctttgagag cctgggcaaa
     5341 gcatggccca ggaacccaga cacccaacgt tgttatcggc aggagctgtg caaactgatg
     5401 tgtgagcggc taagactcag cacgtggaaa gtgcagctag gtgtcctcca gtcaatgaac
     5461 gcctttttcc aggggttaat gcttctggaa gaggaacacg cagatcctga agctctggct
     5521 gagattcttc tcgaaacatg caaatcaatt acttactctt tagaaaataa gacctactca
     5581 tctgtgagaa cagaagcttt atctgtggta gaattactgc ttaaaaaact tgaagaagct
     5641 aaacaatggg aaagtttgac agcagaatgc agaggacttc tgattgagtc tttagctact
     5701 atggagacag acaacagacc agagctgcag gagaaagcct cagtattgaa gaaaacactt
     5761 gaaagtctgg aatgaatgag aaggggaaga aacaaacaag tgccatgttc ttttgggatt
     5821 ggaaatggtg gtatttaaaa aaaaaaaaac caagtggggg aaagtaaagg ttactctgta
     5881 gcatgcatca ttccgtggct gaaataaaaa gaaaaaaagc cttaaatttt gctccttatt
     5941 agctttattt tacttgtctt taaagtctgt gggtaagcga gcttattaac ttgggttttt
     6001 gatatgtctg gcaaccatca ttgctaaaag aactgaaact actataaatg aaatacagga
     6061 caaacaggat taacatctta gaactacatc catgttaaaa tccgtgtagt cagggatcct
     6121 gtaagtcact ccctatgaag caggattggg gatgacaaag cagctttctg aggccaggag
     6181 ccaaggccac agacccaaag tttaatatcc tgtcttggat attttctcaa cctgttacca
     6241 aaccagtgtt tactctgccc ctatcctaga aactcccaaa gtgaggtaca tttagggagt
     6301 catacaatac ttcctatact agagctaaac tgaccctaat cactggattc ttgaagtcac
     6361 atgctctgca tttctcgtgc atataggtgg tcaattttta ggaaatggtt gttcaggatg
     6421 tttataggtt gagaataatt tgagttccat aaaattttga cagatgtcct tttactggaa
     6481 gatgaaaata gattggagca agattagagc aagtctgtct gtatttgtga tcatgtattt
     6541 ttccaaaatc taaaacagca gtaaaaatta gagattacct tgatttagac cacttaaaaa
     6601 tcttaaaact gtaacagtaa cttaacattt tctactccta actgtcatgc atacagtgtg
     6661 acttggaagg acagatggaa agtcttttag ataactgaga atttctgttt tttaagtgcc
     6721 cgctctcaaa ttagcatgat accacttcaa gtaaactgtt gttgccaggg tctttttcct
     6781 gctttctgct gctcctgtac ctgctgaagg gtgcagggtt ggtttaactt aggtgtctat
     6841 agtaagctaa aaactctagc ttgtcttttt ggagcacaag actgatttat atattcaata
     6901 ctatctcctt gatgacatca acacctggaa tctttatgtt cactattttt ggtagaaact
     6961 ccatgtttag tttggtagtc tccagacgag tgtatttcaa aaaattttta actgtgactc
     7021 acaataaaaa taacttaaca tttgattcat aatgtgtgtg tgtctgtgtg tgtgagtgtt
     7081 ggtgtatgta tgtgtgaatg taaaaccttt aactgaaatg tttcatgaag aaatgcttag
     7141 ttgctaagtt tgatagactt tcatctctgt gtctcactgt tgtaaatgtt cttcagactc
     7201 actaaatcat ttcctgattc acaaactagg ttgctattta agtttgaata atactgccac
     7261 tgataatacc taaacttcta ctgtatttga gactgtttct gattgaaaaa ggctttctaa
     7321 ctaaaatgtt cattgctcac tcagtatcat cttggctgat actgggctgt agtagtgagt
     7381 ttgtagaaca tcatgaattt taaagaatct gttgtagaat tgcatttaag aatggctttc
     7441 gctttagtga aaaacaaatg gcttcaaatg ttttttagaa agctctggcc tctcgggata
     7501 tgatgggttt tggaccagca ttggatgcac taaggaccta cctgacttta attgttgtat
     7561 ccaggatgct tccttggcaa ggatgcagtg caggtcaagt tgttgttgaa gatgagaggg
     7621 taagggcaag aataatgtac ttggtttgta gcaagtgttg aaacctcatc aaattttatg
     7681 cttttatagt ttcttgttat ttaacattgg gggtttccct tggtgctgag atggtgctaa
     7741 gacacctgaa ccttagtgca attgcattac atttctttta cgttcctgag cactaattat
     7801 atacttaata cttaattata tacttaatta catacttaat accttcatgt tcgccagccc
     7861 catcattttc acagctagta atgaatgctg tgttactgtt tcaaatacag tttatgtttg
     7921 cgatacatat atatgtttat tttaatcagg actctctaat tgtggaacac gtggtaaaag
     7981 tacctgtaca tgcatatatc atcagtcctt atttgccaaa gctatctcga atgacttgat
     8041 ttcctctctc tattcatttc tgtttgccat acaaatataa ctagtttgga ggacttgttc
     8101 cttattcctg ccattagtgc agtaactgta tctttattga gacatggaaa agatacctgg
     8161 attgtagcag ttggattaac catgaaaatg gtctacagtt ttggtggtca agagtagctg
     8221 tttgattgaa tgtttgtgtc ttatttatag ttcctagggg attttgtcta taacacagtc
     8281 cacttaagta aaagggtacc aaatccccat tgctttgtcc ttcttttttt tttttttttt
     8341 tttttttttt tttttaactc atgtatttac agtaagaaaa agaataaaga tgtgacctca
     8401 ctggttggtg ccctatcagc agttgtgctg tgtgagcact acctgccctt gtggaacatt
     8461 tctacctgct gctgtcacag taattcatgc tgcttgttaa gttcagggag ttattttgac
     8521 attggcactt actgaactgt gcaatctgtc attaaatgga tgtatatgta acagattttt
     8581 gtattttata tgcaacttca tagatcctct gcaatatgta cttagctacc taagcatgaa
     8641 atagacttac tggaaagaaa aaaacctcac tccccaaaga tattaaatgg taaataaaag
     8701 ctgcatgacc tggtgttttg aaaaaaaaaa aaaaaaa
//
