LOCUS       NM_024208               1812 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus enoyl Coenzyme A hydratase domain containing 3
            (Echdc3), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_024208
VERSION     NM_024208.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1812)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1812)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK009166.1.
            
            On Apr 6, 2007 this sequence version replaced NM_024208.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK009166.1, AK004218.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1812              AK009166.1         2-1813
FEATURES             Location/Qualifiers
     source          1..1812
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 3.62 cM"
     gene            1..1812
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
                     /note="enoyl Coenzyme A hydratase domain containing 3"
                     /db_xref="GeneID:67856"
                     /db_xref="MGI:MGI:1915106"
     exon            1..204
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..937
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
                     /note="enoyl-CoA hydratase domain-containing protein 3,
                     mitochondrial"
                     /codon_start=1
                     /product="enoyl-CoA hydratase domain-containing protein 3,
                     mitochondrial precursor"
                     /protein_id="NP_077170.2"
                     /db_xref="CCDS:CCDS15672.1"
                     /db_xref="GeneID:67856"
                     /db_xref="MGI:MGI:1915106"
                     /translation="MAVVAGLRAFGVKWPSWLRRNPWAPLSAGFCSPGSAGPAGSESE
                     PRLTSTRQQDGIRNIVLSNPRRRNALSLAMLKSLRSDILHEAESEDLKVIIISAEGPV
                     FSSGHDLKELTDAQGRDYHAEVFQTCSEVMMLIRNHPVPILAMVNGLATAAGCQLVAS
                     CDIAVASDKSSFATPGVNVGLFCSTPAVALGRAVPRKVALEMLFTGEPISAQEALRHG
                     LISKVVPEEQLEAETMRIAKKISSLSRSVVALGKATFYKQLPQDLRTAYFLASQAMVD
                     NLALQDGQEGIEAFIQKRKPIWSH"
     exon            205..326
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            327..424
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            425..625
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            626..1812
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1069
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
     regulatory      1440..1445
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1458
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
                     /note="major polyA site"
     regulatory      1681..1686
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1701
                     /gene="Echdc3"
                     /gene_synonym="2310005D12Rik"
ORIGIN      
        1 gcttgcacag tcaaccttgc ttttcttggc tgcaatggct gtggtcgcag gccttcgggc
       61 ctttggggtg aagtggccca gctggctcag gcgcaaccca tgggcccctc tctccgccgg
      121 cttctgcagc ccagggtcag caggacctgc ggggtcggag tcagagccaa ggctcaccag
      181 cacgcgacag caggacggaa tcaggaacat tgtcttaagc aatcccagga ggaggaatgc
      241 gctgtcactg gccatgctga aatctctccg aagtgacatt cttcacgaag ctgaaagtga
      301 agacctgaaa gtcattataa tttcagccga gggccctgtg ttttcatctg gacatgattt
      361 gaaagagctg acagatgcac aaggccgtga ttatcacgct gaggtatttc agacctgttc
      421 tgaggtcatg atgctgatcc ggaaccaccc ggtccccatc cttgccatgg tcaatggctt
      481 ggccacagct gcaggctgcc agctcgtggc cagctgtgat attgctgtgg caagtgacaa
      541 gtcttctttt gcaactcctg gagtgaatgt tggacttttc tgctccaccc ccgcggtcgc
      601 cctggggaga gcagtgccca gaaaggtggc cctggagatg ctctttactg gggagcccat
      661 ttctgcccag gaggccttgc gccatggcct tatcagcaaa gtggtaccag aggaacagct
      721 ggaggcagag accatgagaa tagcaaagaa gatttcctct ttgagccgct ctgtggtggc
      781 gttgggcaag gccacctttt acaaacagct gccacaagac cttagaaccg cctacttcct
      841 cgcctcccag gccatggtag acaacctggc cttgcaggat gggcaggaag gaattgaagc
      901 cttcatccag aagagaaagc ccatctggtc acactgagcc cgcatgagga gtgctgagtt
      961 aatggtcagc cctagctgac ccccagccct cccatctcct cctctcaacc caaccatata
     1021 ctgccacctc ttgattgtaa gagaacattg ccagcctttc taacttggat gttggtttct
     1081 cagtgtgtga tctgtattga atgccatggt tctgtgggaa atgaatacag gggagggaac
     1141 gacttgctag gtcagtgggc aggttaatat gcactggggt gtgcaggctg tgacagaaac
     1201 cccagtaccc aacggagcct gaagtgaggt gctgcccata cagaggacag tcaagtgaag
     1261 cgtgaaggaa gggtgccgcc cccatgcttc tgcagtgtcc ttcaggcaca gtccgttctg
     1321 gttgttcatg gcaagttgaa cagttcaaat ctccatgaga ccatctcccc actgaaaaat
     1381 ttcttgattc taccaggaaa tcatcacacc tgtagtttgg aataatctta tgtgatttga
     1441 ataaattaaa tatttataga gctgggtcat ttcatttcta acccaccgca agctaagaaa
     1501 agaaaagaga gaatattctc tttgtatgtc cactctgatg ggcacaaagc aagggccttg
     1561 ccctcactac taaaccagag gataaaagct gcccagaaca gggcaaggac ccagagcaga
     1621 ccccatccaa tgagagtcgc ttcctcagga cacagttcag aactgtgctc agcttctggt
     1681 aataaaccca gactaaactc atatttagac ctagtcatat ttttttggca tctggtctaa
     1741 tgtagcccaa agagtgttca aattttctgt gcctgtaaac ttgaccataa atcaatatcc
     1801 atctatcctc ct
//
