LOCUS       NM_026728               1323 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus enoyl Coenzyme A hydratase domain containing 2
            (Echdc2), transcript variant 1, mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_026728 NM_027252
VERSION     NM_026728.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1323)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1323)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   3  (bases 1 to 1323)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL844206.20, AK166965.1 and AI839329.1.
            
            On Dec 16, 2011 this sequence version replaced NM_026728.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK166965.1, AK153878.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-59                AL844206.20        127246-127304
            60-1304             AK166965.1         2-1246
            1305-1323           AI839329.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..1323
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 50.3 cM"
     gene            1..1323
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /note="enoyl Coenzyme A hydratase domain containing 2"
                     /db_xref="GeneID:52430"
                     /db_xref="MGI:MGI:1289238"
     exon            1..225
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..983
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; enoyl-CoA hydratase domain-containing protein
                     2, mitochondrial"
                     /codon_start=1
                     /product="enoyl-CoA hydratase domain-containing protein 2,
                     mitochondrial isoform 1 precursor"
                     /protein_id="NP_081004.2"
                     /db_xref="CCDS:CCDS18447.2"
                     /db_xref="GeneID:52430"
                     /db_xref="MGI:MGI:1289238"
                     /translation="MLRVLPRALRLPCSWRFSGARDCASHATTRTPEIQVQALTGPNQ
                     GITEILMNRPNARNALGNVFVSELLEALAQLREDQQVRVLLFRSAVKGVFCAGADLKE
                     REQMSDVEVGTFVQRLRGLMSEIAAFPVPTIAAMDGFALGGGLELALACDLRIAASSA
                     VMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLNGAQARELGLVNHAVAQN
                     EEGNAAYHRALALAQEILPQAPIAVRLGKVAIDRGMEVDIASGMAIEQMCYAQNIPTQ
                     DRLEGMAAFREKRAPKFVGK"
     exon            226..293
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /inference="alignment:Splign:2.1.0"
     exon            294..381
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /inference="alignment:Splign:2.1.0"
     exon            382..468
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /inference="alignment:Splign:2.1.0"
     exon            469..561
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /inference="alignment:Splign:2.1.0"
     exon            562..618
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /inference="alignment:Splign:2.1.0"
     exon            619..806
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /inference="alignment:Splign:2.1.0"
     exon            807..857
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /inference="alignment:Splign:2.1.0"
     exon            858..905
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /inference="alignment:Splign:2.1.0"
     exon            906..1307
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1286..1291
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /note="hexamer: AATAAA"
     polyA_site      1307
                     /gene="Echdc2"
                     /gene_synonym="1300017C12Rik; 2610009M20Rik; D4Ertd765e"
                     /note="major polyA site"
ORIGIN      
        1 cttggcgagg cctcgcccgc cccggaacta cgattttcca gctctgccga ggaggtcccg
       61 ttctccgcgc caccttgccg gcctgctccc cgatgctacg cgtactgccc cgcgcgctgc
      121 gcctcccgtg ctcctggagg ttctcggggg cccgggactg cgcctctcac gcgacgacca
      181 ggacacccga aatccaagtg caggctctga caggtcccaa ccaaggaatc actgagattc
      241 tgatgaacag acctaatgcc cgcaatgcct tggggaatgt gtttgttagt gagctgctgg
      301 aagctctggc ccagcttcgg gaagaccagc aagtccgggt cctgctcttc agaagtgcgg
      361 tgaagggagt gttctgtgca ggtgcagacc tgaaggagcg ggagcagatg agtgatgtgg
      421 aggtggggac ctttgtccag cggctccgag gcctgatgag tgagatcgca gccttccctg
      481 tgcccaccat tgcagccatg gatgggtttg ccttaggcgg gggcttggaa cttgccctgg
      541 cctgtgacct ccgaatagca gcttcttcgg ctgtcatggg gctaattgag accactcgag
      601 gacttctccc aggagcagga gggactcaga ggctgcctcg ctgcctgggc gtggccctag
      661 cgaaggagct catcttcaca ggccggcgac tgaacggggc acaggcccgt gagttgggcc
      721 tggtaaatca tgccgtggct cagaatgagg agggtaacgc tgcctaccac cgggccctgg
      781 cactggcaca ggagatcctg ccccaggctc ccattgctgt gcgcctgggc aaagttgcca
      841 tcgacagagg aatggaggtg gacattgcat cagggatggc catagaacag atgtgctatg
      901 cccagaacat cccaacccag gacaggctgg aaggaatggc agccttcagg gagaaacgag
      961 ctcccaaatt tgtgggcaag tgacccagct aactttaagc acacaccata aagtctagat
     1021 catccagaga accaaggtac tgaccatgca gtgcactgcc accttccata ctgctcacct
     1081 tggctagtga ctggactctc tgcattcaaa aacttcgggt ctttgtcatt ggctctgatc
     1141 accatggata gagcaatgag gacttactta ctctcacaga gtttctttga gttagtgtca
     1201 ggagccctcc agctctctgt aacgcaaggg gaattctgga caaactattt aacctctcta
     1261 tcagtctctc tgatatccct gtgttaataa acatgctgca actgttaaaa aaaaaaaaaa
     1321 aaa
//
