LOCUS       NM_026598               2077 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus emopamil binding protein-like (Ebpl), mRNA.
ACCESSION   NM_026598
VERSION     NM_026598.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2077)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   2  (bases 1 to 2077)
  AUTHORS   Moebius,F.F., Fitzky,B.U., Wietzorrek,G., Haidekker,A., Eder,A. and
            Glossmann,H.
  TITLE     Cloning of an emopamil-binding protein (EBP)-like protein that
            lacks sterol delta8-delta7 isomerase activity
  JOURNAL   Biochem J 374 (Pt 1), 229-237 (2003)
   PUBMED   12760743
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY349880.1, AK019963.1 and AC154435.2.
            
            On Mar 24, 2009 this sequence version replaced NM_026598.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.1115123.1, AK019963.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 BY349880.1         4-9
            7-435               AK019963.1         2-430
            436-2077            AC154435.2         96914-98555
FEATURES             Location/Qualifiers
     source          1..2077
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 32.72 cM"
     gene            1..2077
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
                     /note="emopamil binding protein-like"
                     /db_xref="GeneID:68177"
                     /db_xref="MGI:MGI:1915427"
     exon            1..226
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..676
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
                     /note="emopamil binding related protein, delta8-delta7
                     sterol isomerase related protein; emopamil-binding-related
                     protein"
                     /codon_start=1
                     /product="emopamil-binding protein-like"
                     /protein_id="NP_080874.2"
                     /db_xref="CCDS:CCDS27183.1"
                     /db_xref="GeneID:68177"
                     /db_xref="MGI:MGI:1915427"
                     /translation="MGEHWALGPEAGSSLLLCSALLAVGCALGLRLGRGRSAVERWVL
                     AWLCYDSLVHFVLEGAFVYLSIVGNVADSQGLIASLWKEYGKADTRWLYSDPTVVSLE
                     ILTVVLDGLLALVLIYAIVKEKYYRHFVQIVLCVCELYGCWMTFFPEWLVGSPSLNTS
                     SWLYLWVYLVFFNGLWVLIPGLLLWQSWVELKKRDSQEANLAKKHK"
     exon            227..296
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
                     /inference="alignment:Splign:2.1.0"
     exon            297..435
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
                     /inference="alignment:Splign:2.1.0"
     exon            436..2077
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      827..832
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
                     /note="hexamer: ATTAAA"
     polyA_site      849
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
                     /note="major polyA site"
     regulatory      1081..1086
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
                     /note="hexamer: AACAAA"
     polyA_site      1097
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
     regulatory      1435..1440
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
                     /note="hexamer: GATAAA"
     polyA_site      1455
                     /gene="Ebpl"
                     /gene_synonym="5730442K12Rik; EBRP"
ORIGIN      
        1 gcccacaaga ggctagctcg caggctcccc gctcgccgtg gtgtgctgtg gagccatggg
       61 ggagcattgg gcgctgggcc cggaggcagg ctcctccttg ctgttgtgct cagcgctgct
      121 ggccgtaggg tgcgcgctgg gcctgcgcct gggccgcggg cggagcgcgg tggagcgttg
      181 ggtgctcgcc tggctctgct acgactcact ggttcacttt gtgctggaag gcgcttttgt
      241 ctacttgtct atagtaggaa atgttgcaga ttcccaaggc ttgattgcat ctttatggaa
      301 agagtatggc aaggctgaca caagatggct gtattctgat cccaccgttg tgtctttgga
      361 aatcctgact gttgtcctag atgggctcct ggcgttggtc ctcatttatg ccatagtcaa
      421 ggagaaatat tacaggcact ttgtacagat tgtcctgtgc gtgtgtgagc tctatggctg
      481 ctggatgacc ttcttccccg agtggctcgt cggaagcccc agcctcaaca ccagcagctg
      541 gctctacctc tgggtctatt tggtgttttt taatggcctg tgggttctga tcccaggcct
      601 gctgctgtgg cagtcatggg tagaactgaa gaagagagat tcccaagagg ctaatttagc
      661 gaagaagcat aaataagttc tcagggcaac ccattctgac gatctgcttt ccgagtcaga
      721 attgaccaga cattccgatc tgtgctcctt ttttacagtg ttttgaagcg gccattacag
      781 atgggctgga agggggcaaa cttggctgtt tgtttttggt tctttgatta aatgatgata
      841 tgaagagaac ttggggtgtg acttagtagt gttgtgcttg tctagcattc acaaggccct
      901 gaattgttcc cttaacacga ctagggggtg ctgagtacgt tctcacctgt cacagatcat
      961 atttaatgag acgctcagtc atggctggca ggctagttat gccgtgttaa taagtgagtg
     1021 tcaaagatac tgtaaggagt agcatcaatg tttactccaa aaaaaaaaaa cccaaaaaac
     1081 aacaaaaatc aaaacccttt ttgcttcagc ttttattctt ctctgtggtc tcggggttag
     1141 tgacggaaac caaaagcaaa aggagttggt tctgtgttat gcctacaaac ttcaaattgc
     1201 ttcaaatttg tgtgcccaac agagaacgat agtggtaatc tggagtagtg gcgtccaggt
     1261 gtacttggga agctgaggcc ggtggggggc ttgaggctcc ttggggcgat attgtaatat
     1321 tcatttgaaa gaaagaggca gaggagggag actcgatgta aggggcagag ggtgggactg
     1381 tggcaacaca caagaaccaa aaaaatgtgg taaatcttaa cagtacaact ataagataaa
     1441 ttccagaaga ttccatgaag tgcagtttgt gccttaacag tctgggtggc tgaggagggg
     1501 gggcgcaagc ttggtacaga atctgtaccc agatggggca ggatcatgct gggtttcaaa
     1561 ccctggttcc aggaagtgac tgccatggtt ctcttacagg tgggagaggg tactcacaat
     1621 acgacttaac ccatccctct gctcaggaga gcacccacac ctggacccac gcccgcttcg
     1681 tggtactggg cactggagcc aggccgctca ctctttgcca gtctggctgc tggtccagtt
     1741 taggtctctc ttccccttca tctcttattc ttggtcgttt tgttaaacgt atgaaggtca
     1801 gtgtctccag catgctaggc aaccactcca gacttgctac ccacaatcct cctgcctcta
     1861 ccttccaggt gctgagattg aggcgtatgc ccaagccgca gtcctaagtt tgggtcttga
     1921 gtgtgttgct catcagccgg tgttgctgaa gcaggagagg cggtcttagg tggggcctgt
     1981 gaggaagttg acacactagg atttgctctt gaagggatgt caagccccgc ctctctgttc
     2041 tttaactttc ccgccgccat gaagtaaata gctttac
//
