LOCUS       NM_001015681            3720 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus RIKEN cDNA E130308A19 gene (E130308A19Rik), transcript
            variant 2, mRNA.
ACCESSION   NM_001015681 XM_355490
VERSION     NM_001015681.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3720)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK047478.1 and AK081604.1.
            
            On Nov 1, 2013 this sequence version replaced NM_001015681.1.
            
            Transcript Variant: This variant (2) encodes the longer isoform
            (2).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK081604.1, AK087509.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               AK047478.1         2-117
            117-3720            AK081604.1         1-3604
FEATURES             Location/Qualifiers
     source          1..3720
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 32.73 cM"
     gene            1..3720
                     /gene="E130308A19Rik"
                     /note="RIKEN cDNA E130308A19 gene"
                     /db_xref="GeneID:230259"
                     /db_xref="MGI:MGI:2442164"
     exon            1..281
                     /gene="E130308A19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            282..1476
                     /gene="E130308A19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             306..2456
                     /gene="E130308A19Rik"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="uncharacterized protein KIAA1958 homolog isoform
                     2"
                     /protein_id="NP_001015681.1"
                     /db_xref="CCDS:CCDS18223.1"
                     /db_xref="GeneID:230259"
                     /db_xref="MGI:MGI:2442164"
                     /translation="MEDCLHTSSENLSKLVSWAHSHGTICSLIPNLKHLLSEGSHGNL
                     TAMWGCSAGHAYHWPLTATCRAGSQERVCFQDNRSFNSDSPSIIGVPSETQTSPVERY
                     PGRPVKAKLDCNRTRDSCDFSYCSEPSELDEAVEEYEDENTLFDMVCESSVTDEDSDF
                     EPQTQRPQSIARKRPGIVPSSIHSSSQGQMVDECSNDVIIKKIKQEIPEDYYIVANAE
                     LTGGVDGPALSLTQMAKPKPQTHAGPSCVGSAKLIPHVTSAINTELDPHILSASPSVI
                     SRPIIPKTARVSLASPNRGPPGAHGTAHQVTMQMPVSTSHPNKQISIPLSALQLPGQD
                     EQVASEEFLPHLPSQVSSCEVALSPSVNTEPEVSSSQQQPPAAPTITTEATAQCIPAY
                     STKLNKFPVFNINDDLNGLCTSAVSPNTTKATRYALNVWRYWCMTNGLKDHTDITKIP
                     AVKLNELLENFYVTVKKSDGSDFLATSLHAIRRGLDRILKNAGVGFSITSSTFSSSTK
                     KLKEKLWVLSKAGMSGARSRNIVYFSLSDEEEMWQAGCLGDDSPITLLSTVVKYNSQY
                     LNMRTLQEHADLMYGDIELLKDPQNQPYFARTDSVKRESRSGSTRVCHGKIYHEHSRG
                     HKQCPYCLLYKYMYIHRPPTQMEAKSPFYLTARKEATDMGSVWYEEQRMGLRSLRGIV
                     PNLARKVKLENCENFTFVSFTQVSRRLGSHSCCQ"
     exon            1477..1649
                     /gene="E130308A19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1650..3720
                     /gene="E130308A19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2648..2653
                     /regulatory_class="polyA_signal_sequence"
                     /gene="E130308A19Rik"
                     /note="hexamer: TATAAA"
     polyA_site      2669
                     /gene="E130308A19Rik"
                     /note="major polyA site"
ORIGIN      
        1 gctccaagcc gggcgcgcgg agcccggggc gcacggagcg gcgcgcgccg gtggccgagc
       61 caggctggcg cctgcgcccc cccctctcat cgcaccaccg ccgtcacccg ccgcgcagcc
      121 cgtggggcgc ccttcccggt tcaccgactc cggccccggg gcctccggct gtggtgctgc
      181 cgccctccgt cccgccgtcc ctccccgtcc agctcgggcc gccgggctcc cgcaggcccc
      241 accgcccgcg ttcctatgga cagacgcaca gacacctgca ggagagacac tgctgatcct
      301 gtaacatgga ggattgtctt catacctcat ctgagaatct gtccaaattg gtcagctggg
      361 cccacagcca tgggaccatt tgcagcctca ttccaaacct gaaacacttg ctttctgaag
      421 gttcccatgg gaacctgact gcaatgtggg gctgtagtgc cggccatgcg taccactggc
      481 cactaacagc tacttgcaga gctgggtccc aagagagggt ttgtttccag gacaaccgaa
      541 gttttaattc tgatagtccc agtataattg gggtgccttc tgagacacag actagccctg
      601 tggaaaggta ccctgggaga cctgtgaagg caaagctgga ctgtaatcgg accagagact
      661 cttgtgactt ctcttactgc agtgagccct ctgaactgga tgaagctgtc gaggagtatg
      721 aagatgaaaa cacactgttt gacatggttt gcgagtcttc tgttacagat gaggacagtg
      781 actttgaacc ccaaacccag agacctcaaa gcattgctcg caaaaggcca ggaatcgtcc
      841 catcttccat ccattcaagt tcccagggac agatggtcga tgaatgcagt aatgatgtca
      901 tcatcaagaa aatcaagcaa gagattccag aagattatta cattgtggca aatgcagagc
      961 tgactggagg agtggatgga ccagcccttt cattgacaca gatggcaaaa cccaaacccc
     1021 agactcatgc tggtccctcc tgtgtagggt ctgctaaact gattccccat gtaacatctg
     1081 ccatcaacac ggaattagac ccacacattc tgtcagcctc tccctctgtt atctccagac
     1141 cgatcatccc aaagactgct agggtatctc tggcttcacc aaacagagga ccccctggtg
     1201 cccatggcac tgcccaccag gtgaccatgc agatgcctgt gagcacatca catcctaaca
     1261 aacagatcag tatccctttg tctgctctgc agttgcctgg acaggatgag caagttgctt
     1321 cggaggagtt cctgccccac ttgcctagcc aggtctcatc atgtgaggta gccctttctc
     1381 cctctgttaa cacagagcct gaagtgagct ccagtcaaca gcagccccct gctgctccaa
     1441 ccataaccac tgaagccacc gcgcagtgca ttccagctta ttctactaag ctcaacaaat
     1501 ttcctgtatt taatattaat gatgacttga atggtctgtg taccagtgca gtgagcccaa
     1561 acaccaccaa agccacgagg tacgccctaa atgtgtggcg ctactggtgc atgaccaacg
     1621 ggctcaaaga ccacacggac atcaccaaga tccctgcagt gaaactgaat gagctgcttg
     1681 agaactttta tgtcaccgtc aagaagagtg acggctcaga cttcctggct acctcgcttc
     1741 atgccattcg ccgaggcctg gaccgcatcc tgaagaacgc gggtgtgggc ttttccatca
     1801 ccagcagcac cttcagctcc tccaccaaga aactcaagga gaagctgtgg gtcctgagca
     1861 aggcagggat gtcgggggcc cgttcccgca atatcgtcta cttctccctt tctgatgagg
     1921 aggagatgtg gcaggcaggg tgtctagggg atgacagccc aattactctc ctgtccacag
     1981 tggtcaagta caacagccag tatctgaata tgcggactct gcaggaacat gcagatctga
     2041 tgtatggtga catcgagttg ctcaaagatc cgcaaaacca gccctacttt gcccggaccg
     2101 acagtgtcaa gcgggagagc cggagtggtt cgaccagagt gtgccatggg aaaatctacc
     2161 atgagcactc caggggacac aagcagtgtc cttactgcct cctctacaag tacatgtaca
     2221 tccaccggcc acccacccaa atggaggcca agtctccctt ctaccttaca gcccggaagg
     2281 aggccacgga catgggcagc gtgtggtacg aagagcagag aatggggtta cggtctctcc
     2341 ggggaattgt cccaaattta gccaggaagg tcaagctgga aaactgtgag aacttcacct
     2401 tcgtctcctt cactcaggtc tccaggcgac ttggctccca tagctgctgc cagtgagccc
     2461 ccagggccag caggttctga agccgcagag actgatgtcc tcgctccgtg atccagctgg
     2521 tctccgttac tacagccggc cattcctcag acttgagatt cacttttaca tgaaagtcga
     2581 tgactgaata atttggatgt tttatctaaa tgtttgacac cttgttaaat catagaatat
     2641 aacacaatat aaaattacta tatacaaaag tgaagaaatt cattttatct agtgcctttt
     2701 tagcacaggt tttcttggaa aaaaagaaaa gaaaaagaaa aaaaaatgtt ttgagtagtt
     2761 acttaaaaaa tatcccagta gcccagtagc tttagaatgg tatagaatta tatatacttt
     2821 gttggttttc tggggttttt tgtttttccc cacgtaggga cctagagcag gagaggcaga
     2881 catagtagag aaaactctca ctcagcaccc ttgtgttttg ttggggccct ggcagtgggc
     2941 tgcttgcaga aataaaagat acattgttgc tacgctgtct gtccatagag gcagtttggt
     3001 gacaggaaga tcagttctct gaaagggtgt acaggaaaca cggtgtgcag tggactcggt
     3061 ggtgtgcact gtgaggagtt ctagatagcg gagggtggac ttggaaagcc cccgcggccc
     3121 agatgtgaaa cccccccgaa gcagaagtgc ctgcgtctgt ccagttctcc ttagagaaca
     3181 cttgctgttt gaacttcctt ttgtttgttt tgttgtttaa tctgcattgt tacatctcgg
     3241 atttacatct cacagttgtg ttggcaggag tccctggacc tgtgaggcta gcagcgatgc
     3301 ttgactagga gaatcaacag agagagtcac aaggcaaaca ctcccagggc atcttaaggg
     3361 ccctgggaat cctgtaggct ggcactatgt tagggacact gattcaggca gcctgccagg
     3421 aaaccaagcc cggcacaggg acatagttac tggatcagag tgtcacggta ggtcattcct
     3481 gcatttaaaa atcatttcgc attaataaaa gtcaacctga ccatgtgtta cttaaaaagc
     3541 agacttttct agcaactact gtgaatacgt gtttttaaaa tggagcccaa agagtgctaa
     3601 ttaatagtag taatttctac tctattttct attccaggaa agactgctct aattgtacca
     3661 ttatgttctt gtgtatgctt tctaatccca aattaaagcc ccaatgcaca ttcatattgc
//
