LOCUS       NM_001110017            5801 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus DAZ interacting protein 3, zinc finger (Dzip3),
            transcript variant 1, mRNA.
ACCESSION   NM_001110017
VERSION     NM_001110017.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5801)
  AUTHORS   Inoue,D., Aihara,H., Sato,T., Mizusaki,H., Doiguchi,M., Higashi,M.,
            Imamura,Y., Yoneda,M., Miyanishi,T., Fujii,S., Okuda,A.,
            Nakagawa,T. and Ito,T.
  TITLE     Dzip3 regulates developmental genes in mouse embryonic stem cells
            by reorganizing 3D chromatin conformation
  JOURNAL   Sci Rep 5, 16567 (2015)
   PUBMED   26568260
  REMARK    GeneRIF: Dzip3, the E3 ligase of H2AK119, represses
            differentiation-inducible genes in mouse embryonic stem cells.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5801)
  AUTHORS   Zhou,W., Zhu,P., Wang,J., Pascual,G., Ohgi,K.A., Lozach,J.,
            Glass,C.K. and Rosenfeld,M.G.
  TITLE     Histone H2A monoubiquitination represses transcription by
            inhibiting RNA polymerase II transcriptional elongation
  JOURNAL   Mol Cell 29 (1), 69-80 (2008)
   PUBMED   18206970
REFERENCE   3  (bases 1 to 5801)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   4  (bases 1 to 5801)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   5  (bases 1 to 5801)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154447.2.
            
            On Oct 4, 2017 this sequence version replaced NM_001110017.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR6116558.99773.1,
                                           SRR10223970.18614.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-353               AC154447.2         79486-79838
            354-454             AC154447.2         88993-89093
            455-527             AC154447.2         91496-91568
            528-683             AC154447.2         92574-92729
            684-800             AC154447.2         93966-94082
            801-881             AC154447.2         95666-95746
            882-1006            AC154447.2         98081-98205
            1007-1121           AC154447.2         101292-101406
            1122-1241           AC154447.2         112401-112520
            1242-1343           AC154447.2         113872-113973
            1344-1436           AC154447.2         115117-115209
            1437-1489           AC154447.2         115923-115975
            1490-1566           AC154447.2         119825-119901
            1567-2184           AC154447.2         121468-122085
            2185-2217           AC154447.2         123595-123627
            2218-2387           AC154447.2         125052-125221
            2388-2435           AC154447.2         125906-125953
            2436-2461           AC154447.2         128005-128030
            2462-2627           AC154447.2         128700-128865
            2628-2723           AC154447.2         130076-130171
            2724-2851           AC154447.2         131425-131552
            2852-2920           AC154447.2         131908-131976
            2921-3017           AC154447.2         135098-135194
            3018-3121           AC154447.2         136555-136658
            3122-3209           AC154447.2         138042-138129
            3210-3311           AC154447.2         139733-139834
            3312-3437           AC154447.2         142335-142460
            3438-3577           AC154447.2         143873-144012
            3578-3698           AC154447.2         145212-145332
            3699-3824           AC154447.2         145773-145898
            3825-3926           AC154447.2         145985-146086
            3927-5801           AC154447.2         147526-149400
FEATURES             Location/Qualifiers
     source          1..5801
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 30.75 cM"
     gene            1..5801
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /note="DAZ interacting protein 3, zinc finger"
                     /db_xref="GeneID:224170"
                     /db_xref="MGI:MGI:1917433"
     exon            1..353
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            354..454
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     CDS             423..4037
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /EC_number="2.3.2.27"
                     /note="isoform 1 is encoded by transcript variant 1; E3
                     ubiquitin-protein ligase DZIP3; DAZ-interacting protein 3
                     homolog; RING-type E3 ubiquitin transferase DZIP3"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase DZIP3 isoform 1"
                     /protein_id="NP_001103487.1"
                     /db_xref="CCDS:CCDS49866.1"
                     /db_xref="GeneID:224170"
                     /db_xref="MGI:MGI:1917433"
                     /translation="MDSLAEEFFVSGNPDVEEQTKEETEIIAEKPVTQLDKQKMDISA
                     DPEPVNALLEIKKVLNPISALPKGVFPNIEKFIQEDFSFQTMQREVTTHSQTGEEIVP
                     ALTLHFLITQLEMALRNIQASNYTAQQINVGYYLTLLFLYGVALTERAKKEDCIEAEN
                     KFLVMKMVIQESEICENFMCLVYFGRGLLRCAQKRYNGALLEFYKSLQEIGDTDDNWF
                     EVDPTDDEDLPTTFKDSLNNFIKTTESNIMKETICSYLDCERSCEADILKNTNYKGFF
                     QLMCSKSCCIYFHKICWKKFKNLKYPGESDQSFSGQKCLKEGCPGDMVRMLQCDVPGI
                     VKILFEVVRKDEYITIENLGASYKNLMSLELTDTDIRPKFNLKPNTKDEVPIFKLDYN
                     YFYHLLHIIIISGTDMVRQIFDEAMPPTLLKKELLIHKNVLEPYYNHLWTNHPLGGSW
                     HLLYPPNKELPQSKQFDLCLLLALIKHLNVFPAPRKGWDMEPPSSDLSKSADILRLCK
                     YRDILLSEILMNGLTELQFNSIWKKVSDILLRLGMKQDDIDKVKENPIENISLDYHQL
                     SIYLGIPVPEIIQRMLSCYQQGITLQSITGSQRLDVEEFQNDEEDLSPPVMEYNIDVK
                     SNTEIQLAEINKDVASIPSESSTESVKDLQEVKSKTKKKKRTKSNKKDKDSEDEQVSY
                     MVEKDDQLETEQVDVNTLSTYMKTDTSDAQEDSAAEDKFCSLDELHILDMVEQGSSGK
                     ESTDFKETEKERLAHQHQLYKLQYECEDYKRQLKTVTFRWQENQMLIKKKEKIIVSLN
                     QQVAFGINKMSKLQRQIHAKDDEIKNLKDQLSLKRSQWEMEKHNLESTVKTYLNKLNA
                     ETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNLESLQLKAAVDSW
                     NAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEILIQQFLGRPL
                     VKESFFRPILTVPQMPAVCPGVISAAVQPRPPLMPGITWAMPTPIGDTVSPSASLCSE
                     PLMINWERITDRLKTAFPQQTRKELTDFLQQLKDSHGKSVSRLTFDEIVYKISQMIEP
                     KKSESEEKSAQDGNNASPSHTASQPNAPQDPKSAQGSATWEGDKDMDNEEEEEEPCVI
                     CHENLSPENLSVLPCAHKFHSQCIRPWLMQQGTCPTCRLHVLQPEEFPGHPNGQLPKI
                     "
     exon            455..527
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            528..683
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            684..800
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            801..881
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            882..1006
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1121
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1241
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1343
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1436
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            1437..1489
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            1490..1566
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            1567..2184
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            2185..2217
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            2218..2387
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            2388..2435
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            2436..2461
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            2462..2627
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            2628..2723
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            2724..2851
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            2852..2920
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            2921..3017
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            3018..3121
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            3122..3209
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            3210..3311
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            3312..3437
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            3438..3577
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            3578..3698
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            3699..3824
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            3825..3926
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     exon            3927..5801
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5775..5780
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /note="hexamer: AATAAA"
     polyA_site      5797
                     /gene="Dzip3"
                     /gene_synonym="2310047C04Rik; 2A-HUB; 6430549P11Rik;
                     A230104G20"
                     /note="major polyA site"
ORIGIN      
        1 agtctgggag cagcgggtgg gactgcagtc ggtgattggc agggtgggcc tgggttccag
       61 gcgctggggt tgcgggaagg tggcagggag ccatcccctc ccacccccgc cgcagtcccc
      121 ctttggcgga gaggccgcga ggtttcggct ggaggtccgc gaacacgcgg gaatctcgcg
      181 agacgagctc gtgcgggctc attctgtgga gggcttctgg ggcgaacggg ggtctccgtg
      241 ccgcgcgggc tcggtccccg ggccttcctc ggcctgggcg cggcgggctc ggctttccgt
      301 gcgtgcctca gcctctgccc gagacacggc cgctcccccc tagtctagac acgcttttat
      361 gaccatagca aaaatcagtt tgcaggcatt ggaataaatc ttgtaaagga acattgtgca
      421 acatggattc tctagcagaa gaattttttg taagtggaaa tcctgatgtg gaggaacaga
      481 ccaaggaaga aactgagatt atagcagaga aaccagtcac tcagctggac aaacagaaaa
      541 tggatatatc tgctgatcct gagcctgtta acgcactatt agaaataaag aaggtattaa
      601 atccaatcag tgctcttccc aaaggtgtgt tccctaacat tgaaaagttc atacaagaag
      661 atttctcttt ccagactatg cagagggaag ttacaactca tagccagact ggggaagaaa
      721 ttgttcctgc tctaacatta cattttttga taacacaact ggaaatggca cttagaaaca
      781 ttcaagcttc taattatact gcacaacaaa ttaatgttgg ttattatttg acattactat
      841 ttttgtatgg agtggcactc actgaaagag caaagaaaga ggactgcata gaagctgaaa
      901 ataaatttct ggtgatgaag atggtgatcc aagaaagtga gatttgtgaa aactttatgt
      961 gtttagttta ttttggacgt ggtttacttc gatgtgctca gaagagatat aatggagcac
     1021 tactagaatt ttacaaaagc ttacaagaaa taggagatac agatgataat tggtttgaag
     1081 tagatcctac agatgatgaa gatttaccta caaccttcaa agatagtctc aataatttta
     1141 tcaaaacaac tgaaagtaat ataatgaaag agaccatttg cagttatctt gattgtgagc
     1201 gttcttgtga agctgacatt ttaaagaaca ccaattataa gggatttttc cagctaatgt
     1261 gcagtaaaag ttgctgtatt tacttccata aaatttgttg gaaaaagttc aagaacttaa
     1321 agtatccagg agaaagtgat cagagtttta gtgggcaaaa atgtttgaaa gaaggatgtc
     1381 caggtgacat ggtcaggatg ctacaatgtg atgtgcctgg aattgtcaaa attttgtttg
     1441 aagtggtgag aaaggatgaa tatataacca ttgaaaactt aggagcaagt tacaagaatt
     1501 tgatgtctct ggaactaact gacactgata ttagaccgaa attcaattta aaaccaaaca
     1561 caaaagatga agtgcctatc ttcaaacttg attataatta tttctatcat ctgcttcata
     1621 taattattat ttctggtact gacatggtcc ggcaaatatt tgatgaggct atgccaccca
     1681 ctcttttgaa aaaagagctg cttatacaca agaatgtgct ggaaccctac tacaatcatc
     1741 tttggaccaa tcaccctttg ggtggatcat ggcatctgct ttacccccca aacaaggagc
     1801 taccacagtc caaacagttt gacttatgcc tcttattagc gctcattaaa catctgaatg
     1861 tattccctgc acccagaaaa ggctgggata tggaaccacc atcttctgat ctctctaagt
     1921 ctgcagacat tctgaggctc tgcaagtaca gggatatcct tctcagtgag attctgatga
     1981 atggtctcac cgagttacag ttcaattcaa tttggaaaaa agtttctgat attcttctgc
     2041 gccttgggat gaaacaagac gatattgaca aagtcaagga gaatcccatt gagaatatct
     2101 cccttgatta tcatcagctg tccatttatc taggcatacc agtaccagaa atcatccaga
     2161 ggatgttatc ctgctatcaa caaggaatta ctctacagtc aataacaggc agtcagcgtt
     2221 tagatgtaga agagttccag aatgatgaag aagacttgag tccacctgtg atggaatata
     2281 atatcgatgt gaaatcaaac actgagatac agttagcaga gataaataaa gatgtagcct
     2341 cgatacctag tgaatcttca acagaatctg ttaaagatct tcaggaggtc aaaagtaaaa
     2401 caaagaagaa gaaaagaact aagagtaata aaaaggataa ggattcagaa gatgagcaag
     2461 tctcatatat ggtagaaaag gacgaccagc tggagacaga acaagtagac gtgaacacac
     2521 tcagtacata catgaaaact gatacaagtg atgcacaaga agattctgca gctgaggaca
     2581 agttctgtag cctggatgaa ctgcatattc tagatatggt agagcagggc tcatctggaa
     2641 aggaaagtac agacttcaaa gaaactgaaa aggaaaggct tgctcatcaa catcagcttt
     2701 ataaattgca gtatgaatgt gaagattaca aaaggcaact gaaaacagtg acatttcggt
     2761 ggcaggaaaa tcaaatgctg atcaaaaaga aagaaaagat tattgtatct cttaaccaac
     2821 aagtggcttt tgggatcaat aaaatgtcca aattacagcg ccaaatccat gctaaagatg
     2881 atgaaatcaa gaaccttaaa gaccaacttt ccttgaaaag atctcagtgg gaaatggaga
     2941 agcataatct ggaaagcaca gttaaaacat atttaaacaa actaaatgca gaaaccagca
     3001 gagccttaac agccgaggtg tactttttac agtgtcgtag agactttggt ttactacacc
     3061 tcgagcagac agaaaaagag tgcctcaatc agctggccag ggtgacacac atggcagcaa
     3121 gcaacctaga atcacttcaa ctaaaagctg ctgtagatag ttggaatgct attgtggcgg
     3181 atgttcgaaa caagattgca ttcctcagga cacagtacaa tgaacagatc aacaaggtta
     3241 agcaggggtt tgccttgagt accttgcctc cagtccagct tcctccacca ccaccaagtc
     3301 ctgagatact gatacagcaa ttcttaggaa gaccccttgt gaaggaatct ttctttcgac
     3361 ccatacttac tgtccctcaa atgcctgcag tttgccctgg agtcatctct gcagctgtac
     3421 aacctagacc acccctgatg cctggtataa cctgggctat gccaacacct ataggtgata
     3481 ctgtgtcacc gagtgcaagt ctgtgcagtg aacctctcat gataaactgg gagaggatta
     3541 cagacaggct gaaaactgct tttccacaac agacaaggaa agagctaaca gatttcttac
     3601 aacagttaaa ggattctcat ggaaagtccg tgtctcgact gacatttgat gaaattgttt
     3661 acaaaatttc tcaaatgatt gagcccaaga aatctgagag tgaagaaaag tctgctcaag
     3721 atggcaataa tgcttcaccc agccacactg catcacagcc taatgctccc caggacccca
     3781 agtcagcaca aggttctgcc acatgggaag gagacaaaga catggataat gaagaggaag
     3841 aagaggagcc ttgtgtaatc tgtcatgaga atttgtctcc agaaaacctt tcagttttgc
     3901 cttgtgctca caaatttcac tctcagtgca ttagaccatg gttgatgcaa cagggcacat
     3961 gccccacctg cagactccat gttttgcaac cagaagaatt ccctggccac cccaacgggc
     4021 agttacccaa gatctgatac aaggcaggta gctataccta agatcagctt tagacactgg
     4081 gatttagttc tgctttttaa tgagctaatt gtttgaacag tattatgcag cagcatgtgc
     4141 cttgaccagc taatcaaacc aaagctgagt caaagagatt gagacagatc tacagcacgt
     4201 gtaattaaat ggaagagact aaagaacatg gattttattg ctttttgtaa gattttccat
     4261 ctgtaaacac aaggcctgta aacatgacta tcagtatatt tcttagaatg tcctgccttt
     4321 tcagcctttt ttcttccttc ttattctatt gtcttttcct ttctctcaag tatgatatat
     4381 tttattttca tgaaatgagt ttaatagaac aagtagaagg gtaggaaatt tctatagact
     4441 ttagttttct taactttgaa agcttagtat taaaatataa ttattgtaag ttatatttct
     4501 atcttctgaa atggccatac ttgctaagat tatggacttt gacactggtg accatacaat
     4561 ggtttgtaat agcttgggag aggtgattat tatttttcag acagtacaga tcgtttgtca
     4621 acttgttgtt gccatgcaat ttccacaata actatactgt agaaactgca actaagattc
     4681 tcctttcccc caagagctag ttcttaaaaa ttacaccaca agatgtctat attcccaata
     4741 tttagcaaaa taaatataga atgaagttag aatttgaaat caagaggtaa taaaaggggc
     4801 agatatgcaa attaagttat ttgctgggat aagtaattga agttttacat tcctttgtaa
     4861 acatactctt tggttcttag tcatttacat ttggagtaat tagaggtttt tgttgttgct
     4921 gttttgtttt gtcttcgtct ttaaaagtgt ctcctttatg tagttgttct ggggaagaga
     4981 agaagccatt atatgtattg ctgctgctta tgacagagtt gatatccact aaggccagtt
     5041 gtctatcaaa gcttaagttt caattcttag acaataaagc ctattttaaa aactagtgta
     5101 aatacctgta agtattgtac atgcctgtac cttcaaatgt aaagtaagcc acggtacctt
     5161 gtgagacatg tgttccttgt gttccttggt tcatattcac aatctcaact ttattaattt
     5221 ggggggaaag gttttttgac tcagcaacta ttttgtctgt atatttcagt gtaaatgtat
     5281 cttgaagtta ctgtgaatct ctatttaaaa agtcaatgcg tgtaattgta tgctaaactt
     5341 ctttttttat tttgaaatca aactgaaaaa tatgaagaaa aataatttta aaatttcaac
     5401 atctgagggg gtaagttgac ttggcaggta atggtgcttg ttgcagagtt tgctgacctg
     5461 agttctattg ctgggacctg catgctgaaa ggaacaaacc aatagttcac aaattttcca
     5521 ctaactttca tgtgtacatt gtggcttttg tgtgtacatg cacacagtac tcatagatgt
     5581 acaaaagaaa aagaaaagaa agagaatttt ttaaatatgc catttgtcca tatataaaat
     5641 accaacattg tgtttgaatt gcaaaaatct agaacttatg ggacatttaa tcattatgtt
     5701 atcatggtta tgtagcaagt taccttgtaa gatttagttc ttgcttgtaa ttgtaatttc
     5761 atttttatgt ggaaaataaa aatatttctg aattgaatat c
//
