LOCUS       NM_028258               4811 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus DAZ interacting protein 1-like (Dzip1l), transcript
            variant 1, mRNA.
ACCESSION   NM_028258
VERSION     NM_028258.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4811)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4811)
  AUTHORS   Wang,C., Li,J., Takemaru,K.I., Jiang,X., Xu,G. and Wang,B.
  TITLE     Centrosomal protein Dzip1l binds Cby, promotes ciliary bud
            formation, and acts redundantly with Bromi to regulate ciliogenesis
            in the mouse
  JOURNAL   Development 145 (6) (2018)
   PUBMED   29487109
  REMARK    GeneRIF: Dzip1l promotes ciliary bud formation and is required for
            the integrity of the transition zone.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4811)
  AUTHORS   Lu,H., Galeano,M.C.R., Ott,E., Kaeslin,G., Kausalya,P.J.,
            Kramer,C., Ortiz-Bruchle,N., Hilger,N., Metzis,V., Hiersche,M.,
            Tay,S.Y., Tunningley,R., Vij,S., Courtney,A.D., Whittle,B.,
            Wuhl,E., Vester,U., Hartleben,B., Neuber,S., Frank,V., Little,M.H.,
            Epting,D., Papathanasiou,P., Perkins,A.C., Wright,G.D.,
            Hunziker,W., Gee,H.Y., Otto,E.A., Zerres,K., Hildebrandt,F.,
            Roy,S., Wicking,C. and Bergmann,C.
  TITLE     Mutations in DZIP1L, which encodes a ciliary-transition-zone
            protein, cause autosomal recessive polycystic kidney disease
  JOURNAL   Nat Genet 49 (7), 1025-1034 (2017)
   PUBMED   28530676
  REMARK    GeneRIF: Dzip1L knockout mice (wpy mutants) display progressive
            cystic kidney disease and hepatic defects as well as polydactyly,
            facial clefts, and other embryonic malformations.
REFERENCE   4  (bases 1 to 4811)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157949.1.
            
            On Jul 24, 2015 this sequence version replaced NM_028258.3.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099950.1, SRR11927934.7239283.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               AC157949.1         157214-157352       c
            140-715             AC157949.1         148961-149536       c
            716-800             AC157949.1         146985-147069       c
            801-919             AC157949.1         145031-145149       c
            920-1081            AC157949.1         144189-144350       c
            1082-1210           AC157949.1         139668-139796       c
            1211-1273           AC157949.1         137266-137328       c
            1274-1414           AC157949.1         135829-135969       c
            1415-1445           AC157949.1         131993-132023       c
            1446-1499           AC157949.1         131252-131305       c
            1500-1642           AC157949.1         127108-127250       c
            1643-1826           AC157949.1         125778-125961       c
            1827-2043           AC157949.1         123726-123942       c
            2044-2234           AC157949.1         123167-123357       c
            2235-2374           AC157949.1         121029-121168       c
            2375-4811           AC157949.1         116808-119244       c
FEATURES             Location/Qualifiers
     source          1..4811
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 51.93 cM"
     gene            1..4811
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /note="DAZ interacting protein 1-like"
                     /db_xref="GeneID:72507"
                     /db_xref="MGI:MGI:1919757"
     exon            1..139
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            140..715
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             215..2539
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein DZIP1L; DAZ-interacting protein 1-like
                     protein; protein warpy; DAZ-interacting zinc finger
                     protein 1-like; cilium assembly protein DZIP1L"
                     /codon_start=1
                     /product="cilium assembly protein DZIP1L isoform 1"
                     /protein_id="NP_082534.2"
                     /db_xref="CCDS:CCDS23436.1"
                     /db_xref="GeneID:72507"
                     /db_xref="MGI:MGI:1919757"
                     /translation="MQYPAATAEGLSGPLSGAYTLPAFKFQPRRESIDWRRISAVDVD
                     RVARELDVATLQENIAGVTFCNLDGEVCNHCRQPVDPVLLKVLRLAQLIIEYLLHCQD
                     CLSASVAQLEARLQASLGQQQRGQQELGRQADELKGVREESRRRRKMISTLQQLLLQT
                     SAHSYHTCHLCDKTFMNATFLRGHIQRRHAGMADVGKQKQEQPLGEVLEELRAKLKWT
                     QGELEAQREAERQRQVQELEMARQREMEAKKKFDEWKEKERSKLYGEIDKLKQLFWDE
                     FKTVANQNSTLEEKLKALQSYSMTESHLGSLRDEESEERLKHAQEVQALQEKMEVQKT
                     EWKRKMKALHEERAAERRQLQEENERLHVSLSQDQKKAAAQSQRHINALRAQLQEQAR
                     LIESQEETIQTLSLRKVEEVQEMPKAVATEEDSSEEELEASLEERQEQRKVLAALRKN
                     PTWLKQFRPILEDTLEEKLEGLGIKRDTKGISAQTVRRLEPLLRTQREQIARSFREFP
                     SLREKLNKEVSSRVKQRWESTTQPDGQPPVKSQRVTLATREVRPKTRTLTVALPSKPA
                     EPSTPTLQGHSSHGPGLTQVSTPIPRPRVHGPSSTPVSPGSGLSSTPPFSSEEEPEGD
                     VVQRVSLQPPKVLPRSAAKPEDNWGWSDSETSEESAQPPGKGSGGLASSGTLVQSIVK
                     NLEKQLETPAKKPSGGVNMFLRPNAALQRASTPARKSQLSEDESDVEISSLEDLSQDL
                     GQKGKPKPLSHSKLPEKFDVSPWSSGSRPRIPGW"
     exon            716..800
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            801..919
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1081
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1082..1210
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1273
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1414
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1415..1445
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1499
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1500..1642
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1826
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1827..2043
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2044..2234
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2235..2374
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2375..4811
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3598..3603
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3621
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
     regulatory      3967..3972
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /note="hexamer: AATATA"
     polyA_site      3992
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /note="major polyA site"
     regulatory      4765..4770
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
                     /note="hexamer: AATAGA"
     polyA_site      4807
                     /gene="Dzip1l"
                     /gene_synonym="2610524A10Rik"
ORIGIN      
        1 ggggtagggg ttggggtggg aagcaccgca gaccccaggc ctgagctact ggcggggaga
       61 gacgcgtagg gtccgcgcgg ctggcagcat cctcgggctg cactgtagga gatggagtga
      121 gtctggactt gcggatgggg tcctctttca gctccttggc ccgtggtcct ggtggcattc
      181 tacccctgtg gtcagcccag agcctcttct gcccatgcag tacccagcag ccactgcgga
      241 aggccttagt ggcccgctgt ccggggccta cacgcttccc gccttcaagt tccagcctcg
      301 ccgtgaaagc atagactgga gacgaatcag tgccgtggac gtggaccgtg tggcccggga
      361 gctggacgtg gccacactgc aggagaacat tgctggcgtc accttctgta acctggacgg
      421 ggaggtgtgc aaccactgta ggcagccggt ggacccggtg ctgctcaagg tactgcgcct
      481 ggcacagctc atcattgagt acctgctgca ttgccaggac tgcctgagtg ccagcgtggc
      541 acagctggaa gcacggctgc aggccagcct gggccagcag cagcgtggcc agcaggagct
      601 gggtcgccag gccgatgagc tcaagggcgt tcgggaggag agccggcgta ggcgaaagat
      661 gatcagcacc ctgcagcagc tgcttctgca gacgagtgcc catagctacc acacgtgcca
      721 cttgtgtgac aagaccttca tgaatgccac ctttctccgg ggccacatcc aacgcagaca
      781 tgcaggcatg gcagatgtcg gaaagcagaa gcaggaacag ccactggggg aggtgctgga
      841 ggagcttcgg gccaagctca agtggaccca aggggagctg gaagcccaga gggaggctga
      901 gcggcagcgg caggtccagg aattagagat ggctcgtcag cgggaaatgg aagctaaaaa
      961 aaagttcgat gaatggaaag aaaaagaacg cagcaagctt tatggagaga tagacaagct
     1021 gaaacagctg ttttgggatg aattcaaaac tgttgccaac cagaactcca cgttagaaga
     1081 gaaactgaag gcactgcagt cctacagcat gacggagtct caccttgggt ctctgcggga
     1141 tgaagagtca gaggagagac tcaagcatgc ccaggaggtc caggcccttc aagaaaagat
     1201 ggaagtccag aaaacagagt ggaagaggaa aatgaaggcc ctgcatgaag agcgggcagc
     1261 tgagaggaga cagctgcagg aggagaatga gaggctccac gtgtccctgt ctcaggacca
     1321 gaagaaagca gctgcccagt ctcagcgcca tatcaatgcc ctccgtgccc agcttcaaga
     1381 acaagccagg cttatcgagt cccaggagga gacgatccag actttgtccc tcaggaaggt
     1441 ggaggaagtc caagagatgc caaaggctgt ggccacagag gaggactctt ctgaagaaga
     1501 gctcgaggcc tcccttgagg agcggcagga gcaacggaag gtgttagcag ctctcaggaa
     1561 aaaccccact tggctgaagc agttccggcc catcctggag gacaccctgg aagagaagct
     1621 ggagggcctg gggatcaaga gggacacaaa gggaatttct gctcagactg tccgacgtct
     1681 ggagcccctg ctgagaaccc aaagggagca gatagcccga agcttccgag agtttcccag
     1741 tctgagggaa aagctcaaca aggaagtgag cagcagggtg aagcaaagat gggagagtac
     1801 gacccagcca gatggccagc ctccagtcaa aagccagcgg gtcacactgg ccacaaggga
     1861 ggtccggcca aagaccagga ccttgactgt ggccctgcca tccaaaccag cagaaccttc
     1921 aacgccaact cttcagggcc acagcagcca tggccccggc ctcacccagg tgtccacccc
     1981 cattccacgc cccagagtgc atggaccctc cagtacccct gtttcccctg ggtccgggct
     2041 gagcagcacc ccgcctttta gttctgaaga agagccagag ggagatgtcg tgcaacgtgt
     2101 gtcccttcag cctcctaaag ttctccctag gtcagcggcc aagcctgagg acaactgggg
     2161 ctggtctgat tccgagacct cagaggagag tgcccaacct cctgggaagg gctcaggcgg
     2221 gctggcttct tcaggaacac tggtgcagtc aattgtcaaa aaccttgaga agcagcttga
     2281 aacgccagcc aagaagcctt ccggaggggt caatatgttc ttaaggccca acgctgccct
     2341 ccagagggct tccacaccag caaggaagtc tcagctttca gaagatgaga gtgacgtgga
     2401 gatctcgtct ttggaagatc tctcccaaga cctgggccag aaaggaaagc caaagccttt
     2461 gtcccactca aagctcccag aaaagtttga tgtcagccct tggagctcgg ggtcacgacc
     2521 caggattcct ggctggtgat tctcttatgt ttgccagagg gcttagcctt gtttcttggc
     2581 tggtctcacc caaatggaag aggccgtcag gcctcccgct ctcactagca gccaagaaat
     2641 ctttcccttg aagagaagca gggtaggaga cagacagaac ctctatccac cccccgaccg
     2701 ctaccccaaa aggctggctc ctggtgctgg gtcttgtgta aatgtgagag ggattgtaac
     2761 aggacttcct agtgtttctt ccatgatccc catgtccagc ccagactgaa agtagttact
     2821 ctttctaagt ttttgtaatc tgcaggtcaa cgtggagttg ggttctgagt cagttaccag
     2881 ttaggtagtc tatggtggac tctctagctt ttcactactg aattggggtg cagacagagg
     2941 taagaggtac aacgtgcttg ctaccagggc caggcatagt aatcgagtgc tagcctgcta
     3001 ccagggccag gcatagtaat cgagtgctag cctgctacca gggccaggca tagtaatcga
     3061 gtactaggca ttagagtgtt gggatggcat ggttgaggct ggctgcccta ctttcatttc
     3121 tgttgctgtg ataaacactc cgaccaaaag caccttagag gaagaaaggc tttgttagtc
     3181 tatgactgca aggagatgaa ggctggacca tgaaggtaga cctgcttgct gttccacaca
     3241 gcactacctc tgaccaagta attcacttca cagccaaaga aacatgttag gaaccctaga
     3301 ggatactgct tgctaactgc agctgtgtgc tagctctttt tatacagttc aggacctcct
     3361 gcctagggat ggtactgccc acagtaggct gggttctcct acatccgtga acaatctaga
     3421 caatccctca cagacattgc cctcaaagca cttcctctga ggaggctctc ctcttggaca
     3481 gttctcagtt gtgacaaatg gatatttaaa actaaccaga acaccattcc acccagtcca
     3541 ggatgaccct ggagaaagcc ccagagttgt gttgtgtggt ggagcttggt catgggcaat
     3601 aaaaagagca atctggatga agcctcttgt ccccaataga accataaatt taatttttga
     3661 gattgtttct gaatgagatt tttttatata tattgactgt atttttgggc agagaggggt
     3721 tgggttttaa aaatattttt atttattatt attttttatt tttttatttt ttttgagaca
     3781 gggtttccct gtgtggccct ggctgttctg gaactctctc tacagcctag gctgctcttg
     3841 aactcagaga tctgcctgcc tctgcctcct gagtgctgag attaaagatg tccatggtgg
     3901 cacgtagctt acattgtatt tttttttttt agtgtgaaaa catttattta ttatactgaa
     3961 catttaaata taatgatgta tacacctctt tattatgtcg ttctttgtta tttttttcaa
     4021 gctttgtggc gactgagggt ggtgaagagg gagtgaagca gcttccacct cagttgtacc
     4081 agcttagggc ctttgggatg cagtgatcga ggtgtggtaa gacagccagt tttactgagg
     4141 tgctttacct gggcaaggta aaggtggctg aaatggggtc tgacagcgga agattgcaga
     4201 gtggaaaaat ggaaaggcat gttctagtca gtgctctatt gctgtgaaca gacaccatga
     4261 ttgtggccag tcttataaag gcaaacattt aagtagagct ggcttacagt ttcagaggtt
     4321 cagtccattg ccatcatgga ggggagcatg ggcacacagg cagacatggt tcaggcagca
     4381 ggaagagaga gatactggtc ctggcttggg ctctgaaact tcaaagccca cccccagtga
     4441 cacacttcct ctaacaaggc cacacctcca ccaacaaggc cacactccat aatcctttca
     4501 aatagtgcca ctccctggtg accaagcatt caaatctgtg tgcctgtagg ggccatgctt
     4561 attcaaacta ccacaaggca gaaacaggga gaacccagac agcaatgcag ggctctcaca
     4621 ggagagctac agagtcagga ctgcctactg tagtgtcccc aaacctttgt tactgcactg
     4681 tgctttatca ttggctgggg gatcctgggg tcgcatgaga cctcagctgt gaactctgtc
     4741 agccaattat attccttgca tttgaataga gactttaata tcctaagaga aaaatagtca
     4801 tcttaaacgc t
//
