LOCUS       XM_006506163            6957 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus dysferlin (Dysf), transcript variant X1,
            mRNA.
ACCESSION   XM_006506163
VERSION     XM_006506163.3
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000072.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_006506163.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6957
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="6"
     gene            1..6957
                     /gene="Dysf"
                     /gene_synonym="2310004N10Rik; D6Pas3"
                     /note="dysferlin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 2 mRNAs, 34 ESTs, 42 long
                     SRA reads, 6 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 5 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:26903"
                     /db_xref="MGI:MGI:1349385"
     CDS             261..6728
                     /gene="Dysf"
                     /gene_synonym="2310004N10Rik; D6Pas3"
                     /codon_start=1
                     /product="dysferlin isoform X1"
                     /protein_id="XP_006506226.1"
                     /db_xref="GeneID:26903"
                     /db_xref="MGI:MGI:1349385"
                     /translation="MLCCLLARASNLPNVKKDRRSDPVASLIFRGVKKRTKVIKNSVN
                     PVWNEGFEWDLKGIPLDQSSELLVVVKDHETMGRNRFLGEAKIPLQEVLATPSLSASF
                     NAPLLDAKQQPTGASLVLQVSYTPPPGAVPLFPPPASLAPSPTLPDMDLVPGGGQSRA
                     ETWSLLSDSTMDTRYSGKKWPVPTDTGGEEDTEDQGLTGDEAEPFLDQSAAVGPGGPT
                     TPRKPPSHPPPHYPGAKRKRSSAPPRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVK
                     VTAAGQTKRTRIQKGNSPLFNETLFFNVFDSPLELFDEPIFITVVDSRSLRTDALLGE
                     FRMDVGTVYREPRHAYLRKWLLLSDPDDFSAGARGYLKASLCVLGPGDEAPLDKKDPS
                     EDKEDIEGNLLRPTGVALRGAHFCLKLFRAEDLPQMDDAVMDNVKQIFGFDSNKKNLV
                     DPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRVMDWDRLTHNDT
                     VATTYLGMSKISATGGEIEEEPAGVLKSPQATDLDDNLGFLPTFGPCYVNLYGSPREF
                     TGFPDPYAELNTGKGEGVAYRGRVLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRR
                     KYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDTTCLPLASTTQYSRAVFDGCHYY
                     YLPWGNVKPVVVLSSYWEDISHRIEIQNQLLRVADRLEANLEQVHLALKAQCSSEDVD
                     ALVAQLTDELLADCSQPLCDIHEIPSATHLDQYLLRLRTRHLSQIKEAALALKLGHSE
                     LSTALEQAEDWLLHLRALAEEPQNSLPDIIIWMLQGDKRVAYQRVPAHEVLFSRRGPS
                     YCGRNCGKLQTIFLKYPMEGMPGARMPVQIRIKLWFGLSVDEKEFNQFAEGKLSVFAE
                     TYENQTKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWAWAGDWFVCPEKTL
                     LHDADAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWED
                     EEWSTDLNRAVDEQGWEYSITIPPDRKPKHWVPVEKMYYTHRRRRWVRLRRRDLSQME
                     ALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFAL
                     EGALGGMVDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYLYQARDLPAMDKD
                     SFSDPYAIVSFLHQSQKTVVEKNTLNPTWDQTLIFYEIEIFGEPASIAEHPPCIVVEL
                     YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPAGELLAAFELIQREKPAIHH
                     IPGFEMHETSRILDELCTPAFFLQGFLRTSTTEDTDLPYPPPQREANIYMVPQNIKPA
                     LQRTAIEILAWGLRNMKSYQMASISSPSLVVECGGQTVQSCVIRNLRKNPNFDVCTLF
                     MEVMLPREDLYCPPIVVKVIDNRQFGRRPVVGQCTIRSLENFLCDPYSAESPSPQGGP
                     DDVSLLSPGEDVLIDIDDKEPLIPVQLTDGLSSLGPTNLTPSPSSPHKILLEEEFIDW
                     WSKFFASVGEREKCGSYLEKDFDTLKVYDTQLENVEAFGGLSDFCNTFKLYRGRTQEE
                     TDDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPK
                     DPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYD
                     LLSKDEKIGETVIDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH
                     RIKAPVYRTDRVTFQDKDYTIEEIEAGRLPNPHLGPVEERLALHVLQQQGLVPEHVES
                     RPLYSPLQPDIEQGKLQMWIDIFPKVLGRPGPPFNITPRKARRFFLRCIIWNTKDVIL
                     DDLSLTGEKMSDIYVKGWMVGFEEHKQKTDVHYRSLGGEGNFNWRFVFPFDYLPAEQV
                     CAVAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAEK
                     CSLDQLDDTFHPEWFVSLFEQKTVKGWWPCVTEEGEKKMLAGKLEMTLEIVAESEHEE
                     RPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRCAIILFIILFILL
                     LFLGVFVYAFPNYAAMKLVKPFR"
ORIGIN      
        1 ccagagtaat tccttgctcc tccttggcca ccgccctgag ggcggaccca ggccgggatg
       61 gaaggaagga tccgccccct gggtgtacct tatcccacgc gcagcctcgc attctaagct
      121 gaccaagtct ccgcggaggc gcagcagaat caactgctct cttggcatag ccatcctgga
      181 tctgaactct ggcagggcag tagtgactga gtcctaagct cctactccct ctccgtccca
      241 cgcgcctggg ctgcggagcc atgctctgtt gcttgctggc aagggccagc aacctcccca
      301 atgtgaagaa ggaccggcgc agcgatccag ttgccagcct gatttttcga ggggtaaaga
      361 agagaaccaa agtcatcaag aacagtgtga accccgtgtg gaatgagggc tttgagtggg
      421 acctcaaagg tattcctcta gatcagagct cagaacttct cgtggtggtc aaggaccatg
      481 agacgatggg aagaaacagg ttcctggggg aagccaagat cccactccag gaggtccttg
      541 ccacccccag cctctctgcc agcttcaacg cacctctgct agacgccaag cagcaaccca
      601 cgggggcctc tctggtcctg caggtgtcct acacgccacc cccaggagct gtgcccctgt
      661 tcccaccacc tgcttctcta gcaccctccc cgacactgcc tgacatggat ctggtgcctg
      721 gtgggggaca gagccgggct gagacttggt ccctgctcag tgacagcacc atggacacga
      781 gatactctgg gaagaagtgg ccggtcccca cggacacagg aggggaggaa gacaccgagg
      841 accagggcct gactggagat gaagctgagc cgttcctgga ccagagtgct gctgtgggcc
      901 cagggggacc gaccacaccc aggaagccac cttcccaccc tcctccccac tatccagggg
      961 caaaaagaaa aagaagctct gccccaccta gaaagctgct gtcagacaag ccacaggact
     1021 tccagatcag agtccaggtg atagaggggc gtcagctgcc tggggtgaat attaagcctg
     1081 tggtcaaggt cacagctgct gggcagacca agcgaactcg gatccagaag ggaaatagcc
     1141 cactcttcaa tgagactctt ttcttcaacg tatttgactc tcccttggag ctgtttgatg
     1201 agcccatctt catcacggtg gtggactcac gctcccttag gacagatgcc ctccttggcg
     1261 agttccggat ggatgtgggc accgtgtaca gagagccccg acacgcttat ctccggaagt
     1321 ggctgctgct ctccgaccct gatgacttct ctgcgggggc cagaggctac ctcaaagcca
     1381 gcctgtgtgt gctagggcct ggagatgaag ctcccctgga caagaaggac ccttctgaag
     1441 acaaagagga cattgaaggc aacctgctta ggcccaccgg tgtggccctt cgaggagccc
     1501 acttctgcct gaagctcttc cgggctgagg acttaccaca gatggacgat gctgtgatgg
     1561 acaacgtcaa gcagatcttt ggctttgaca gcaacaagaa gaacttggtg gatccctttg
     1621 tggaagtcag ctttgctggg aaaatgctct gcagcaagat cctggagaag acagctaacc
     1681 ctcagtggaa ccagaacatc accttgcctg cgatgtttcc ctctatgtgt gaaaaaatga
     1741 ggattcgtgt catggactgg gaccgcctca ctcacaatga cactgtggcc accacctact
     1801 tgggtatgtc gaaaatctct gctactggag gagaaataga agaggagcct gcaggtgtac
     1861 tcaagagtcc acaagccact gacctggacg acaacctggg cttcctcccc acttttgggc
     1921 cctgctatgt gaacctctat ggcagtcccc gagagttcac gggcttccca gatccttatg
     1981 cagagctcaa cacaggaaag ggagaaggtg tggcttatcg aggcagggtt ctgttgtccc
     2041 tggagaccaa actggtggaa cacagtgagc agaaggtgga agaccttcct gctgatgata
     2101 tcctgcgtgt ggagaagtac ctgcggaggc gcaaatattc cctctttgct gccttctact
     2161 cagccacaat gctgcaggat gtggatgacg ccatccagtt cgaggtcagc attgggaact
     2221 acgggaacaa gttcgacacc acctgcctgc ccttggcctc caccacccag tacagccggg
     2281 cggtctttga tggatgccac tactattact tgccttgggg caacgtgaag cccgtggtgg
     2341 tgctgtcctc atactgggaa gacatcagcc atcgaattga gatccaaaac cagctcctca
     2401 gggtcgctga ccgcctggaa gctaacctgg agcaggtcca cttggctctg aaggcacagt
     2461 gttcctccga ggatgtggac gccctggtgg ctcagttgac agatgagctc cttgcagact
     2521 gcagccagcc cctgtgtgac atccacgaga taccttctgc cacccacctt gatcagtacc
     2581 tgctccggct acgcacccgt cacctgagcc agatcaaaga agctgctctg gccttgaagc
     2641 ttggccatag tgagctctcc actgccctgg agcaggccga ggactggctt ctgcatctcc
     2701 gtgccctggc cgaggagccc cagaacagcc tgccggacat catcatctgg atgctgcagg
     2761 gtgacaagcg tgtggcctac cagcgggtgc ctgcccatga agtcctcttc tcccggcggg
     2821 gccccagcta ctgcggcagg aactgtggga agctgcagac catctttctg aaatatccta
     2881 tggaaggtat gcctggggcc cgaatgcccg tgcagattcg gatcaagctc tggttcgggc
     2941 tctctgtgga tgagaaggaa ttcaatcagt ttgctgaggg aaagctctct gtctttgccg
     3001 aaacgtatga gaaccagaca aagctggcac tggtcgggaa ctggggcaca acgggcctca
     3061 cctaccccaa gttttctgat gtcacaggca agatcaaact accaaaggat agcttccgcc
     3121 cctcagctgg ctgggcctgg gcaggagatt ggttcgtgtg tccagagaag accctactcc
     3181 atgatgctga cgctggtcat ctgagcttcg tggaggaggt gttcgagaac cagacccggc
     3241 tccctggggg ccagtggatt tacatgagtg ataactacac agatgtgaat ggggagaagg
     3301 tacttccgaa ggatgatatt gaatgcccgc tgggctggaa gtgggaagat gaagaatggt
     3361 ccacagacct caatcgggct gttgatgaac aaggctggga gtacagcatc accatacccc
     3421 cagaccgaaa gccaaaacac tgggtccctg ttgagaagat gtattacact cacaggcgtc
     3481 gacgctgggt ccgactgcgc aggagggacc tcagccagat ggaagcactg aagaggcaca
     3541 ggcaggcaga ggccgagggc gagggctggg agtatgcctc tctcttcggc tggaagttcc
     3601 acctggagta ccgcaagaca gatgccttcc gccgccgccg ctggcgccgc cgcatggagc
     3661 cgctggagaa gacgggacct gcagctgtgt ttgccctcga gggggccctg ggcggcatgg
     3721 tggatgacaa gagcgaagac tccatgtctg tttctaccct gagctttggc gttaacagac
     3781 ccacaatctc ctgcatcttt gactatggga accgctacca tctgcgctgc tacctgtacc
     3841 aggcccgaga cctgccagcc atggacaagg actccttctc tgatccctac gccatcgtct
     3901 ccttcctgca tcaaagccag aagacagtgg tggagaagaa caccctgaat cccacctggg
     3961 atcaaaccct catcttctat gagattgaga tcttcggcga gccagccagt atcgccgagc
     4021 atccgccctg catcgtggtg gagctctatg accacgacac ctatggtgct gacgagttca
     4081 tgggtcgctg tatttgtcag ccaagcctgg aacggatgcc ccgcctggcc tggttcccac
     4141 tgacccgggg cagccagcct gccggcgagc tgctggcagc gttcgagctt atccagagag
     4201 agaagccagc catccatcac atccctggct ttgagatgca tgaaacttca aggattttgg
     4261 atgagctatg cacgcctgcc ttcttcctgc agggcttcct tcggacgagc acgacggagg
     4321 acacagattt gccttaccca ccacctcaaa gggaggccaa catctacatg gttccccaga
     4381 acattaagcc agctctccaa cgtactgcca ttgagatcct ggcctggggc ctgcggaaca
     4441 tgaagagcta tcagatggcc agcatctctt cccccagcct cgtggtggag tgtggtgggc
     4501 agacagtgca gtcctgtgtc atcagaaacc ttcggaagaa ccccaacttt gatgtctgta
     4561 ctctcttcat ggaagtgatg ttacccagag aggacctcta ctgtccacct attgtggtca
     4621 aggtcattga taatcgccag tttggccgcc ggccagttgt gggtcagtgt accattcgct
     4681 ccctggagaa cttcctgtgc gacccatact cagcagagag tccatcccca cagggtggcc
     4741 cagatgatgt gagcttactc agccccgggg aagatgtgct gattgacatc gatgacaagg
     4801 agcctctcat tcctgtccag cttacagatg ggctgtcaag cttgggcccc actaacctga
     4861 cgccttctcc atccagtcct cataagatcc tcctggagga ggagttcatt gactggtgga
     4921 gcaaattctt tgcttctgtc ggggagaggg aaaagtgtgg ttcctacctg gagaaggatt
     4981 ttgacacctt gaaggtctat gacacacagc tggagaatgt ggaggctttt ggaggcctgt
     5041 ccgacttttg taacaccttc aagctctacc ggggcaggac tcaggaggag acagatgatc
     5101 catctgtcat cggagaattt aagggtctct tcaaaattta tcccctccca gaagatccag
     5161 ccatccccat gcccccgaga caattccatc agctggctgc tcagggtccc caggaatgct
     5221 tggtccgtat ttatatcgtc cgagcatttg gcttacagcc caaggacccc aatggcaagt
     5281 gtgaccctta catcaagatc tccataggga agaaatcagt gagtgaccag gataactaca
     5341 tcccttgcac cctggagcct gtattcggaa agatgtttga actcacctgc actctacctc
     5401 tggagaagga cctgaagatc acactctacg attatgacct gctctccaag gatgagaaga
     5461 ttggggagac ggtcatagac ctggagaaca ggctgctgtc caagtttggg gctcgctgtg
     5521 ggctcccaca gacctactgt gtctctggac caaatcagtg gagagatcag ctccgcccct
     5581 cccagctcct ccacctcttc tgccagcagc acaggatcaa ggcccccgtg taccggacag
     5641 accgagtgac gtttcaggat aaggactaca ccattgagga gatagaggct ggcagactcc
     5701 caaacccaca cctgggccca gtggaggaac gcttagccct gcatgtcctt cagcaacaag
     5761 gcttggttcc tgagcatgtg gagtcacggc ctctttatag tcctctgcag ccagatatcg
     5821 agcaggggaa gctacagatg tggattgaca tatttccaaa ggtgctgggc cggcctggac
     5881 ctcccttcaa catcacccca cggaaagcta gaaggttttt tctgcgttgt attatttgga
     5941 acacaaaaga tgtgatcttg gatgacctca gtctcacggg ggagaagatg agtgacatct
     6001 atgtgaaagg ctggatggtg ggattcgaag aacacaagca gaagacagat gtgcactacc
     6061 gctccctggg tggggagggc aatttcaact ggaggttcgt gtttcccttc gactatctgc
     6121 ctgctgagca agtctgtgct gttgccaaga aggatgcctt ctggagactc gacaagacag
     6181 agagcaagat cccagcacgt gtggtcttcc agatctggga caatgacaaa ttctcttttg
     6241 atgactttct gggctctctg cagctggatc tcaaccgaat gcccaagcca gccaagacgg
     6301 ctgagaagtg ctccttggac cagctggatg acaccttcca cccagaatgg tttgtgtccc
     6361 tttttgagca gaagacagtg aaaggatggt ggccttgtgt gacagaggag ggcgagaaga
     6421 agatgttggc gggcaagctg gaaatgacct tggagattgt tgcagaaagt gaacatgaag
     6481 agcggcctgc tggccaaggt cgggatgaac ccaacatgaa tccgaagcta gaggatccaa
     6541 ggcgccccga tacttctttc ctgtggttca cctccccgta caagaccatg aagttcatct
     6601 tgtggcgacg cttccggtgt gccatcatcc tcttcatcat cctcttcatc ctcctgctct
     6661 tcctgggtgt ctttgtctac gccttcccga actacgctgc catgaagctg gtgaagccct
     6721 ttcgatgaag aagacatctg ctctggagaa gggggtgcag gctgcctcct ggcccaggac
     6781 tagctgctcc tccattgctc tggggcctgg tggtcttgcg catgtccatg gagttcttgg
     6841 gaatcacgtt attttcatct tctctttctc ccctaaccca acactcctct ggataaactc
     6901 ttggctttct cagtataaag cagacagaac cagaaaatat attgctatgt gtctaca
//
