LOCUS       NM_025975               2153 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus dynein light chain Tctex-type 3 (Dynlt3), mRNA.
ACCESSION   NM_025975
VERSION     NM_025975.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2153)
  AUTHORS   He,S., Gillies,J.P., Zang,J.L., Cordoba-Beldad,C.M., Yamamoto,I.,
            Fujiwara,Y., Grantham,J., DeSantis,M.E. and Shibuya,H.
  TITLE     Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate
            mitotic and male meiotic spindle bipolarity
  JOURNAL   Nat Commun 14 (1), 1715 (2023)
   PUBMED   36973253
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2153)
  AUTHORS   Aktary,Z., Conde-Perez,A., Rambow,F., Di Marco,M., Amblard,F.,
            Hurbain,I., Raposo,G., Delevoye,C., Coscoy,S. and Larue,L.
  TITLE     A role for Dynlt3 in melanosome movement, distribution, acidity and
            transfer
  JOURNAL   Commun Biol 4 (1), 423 (2021)
   PUBMED   33772156
  REMARK    GeneRIF: A role for Dynlt3 in melanosome movement, distribution,
            acidity and transfer.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2153)
  AUTHORS   Karataeva,A.R., Klaassen,R.V., Stroder,J., Ruiperez-Alonso,M.,
            Hjorth,J.J., van Nierop,P., Spijker,S., Mansvelder,H.D. and
            Smit,A.B.
  TITLE     C-terminal interactors of the AMPA receptor auxiliary subunit
            Shisa9
  JOURNAL   PLoS One 9 (2), e87360 (2014)
   PUBMED   24498314
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2153)
  AUTHORS   Huang,X., Wang,H.L., Qi,S.T., Wang,Z.B., Tong,J.S., Zhang,Q.H.,
            Ouyang,Y.C., Hou,Y., Schatten,H., Qi,Z.Q. and Sun,Q.Y.
  TITLE     DYNLT3 is required for chromosome alignment during mouse oocyte
            meiotic maturation
  JOURNAL   Reprod Sci 18 (10), 983-989 (2011)
   PUBMED   21693773
  REMARK    GeneRIF: Data suggest that DNYLT3 is required for chromosome
            alignment and homologous segregation during mouse oocyte meiosis.
REFERENCE   5  (bases 1 to 2153)
  AUTHORS   Banks,G.T., Haas,M.A., Line,S., Shepherd,H.L., Alqatari,M.,
            Stewart,S., Rishal,I., Philpott,A., Kalmar,B., Kuta,A., Groves,M.,
            Parkinson,N., Acevedo-Arozena,A., Brandner,S., Bannerman,D.,
            Greensmith,L., Hafezparast,M., Koltzenburg,M., Deacon,R.,
            Fainzilber,M. and Fisher,E.M.
  TITLE     Behavioral and other phenotypes in a cytoplasmic Dynein light
            intermediate chain 1 mutant mouse
  JOURNAL   J Neurosci 31 (14), 5483-5494 (2011)
   PUBMED   21471385
REFERENCE   6  (bases 1 to 2153)
  AUTHORS   Duguay,D., Belanger-Nelson,E., Mongrain,V., Beben,A.,
            Khatchadourian,A. and Cermakian,N.
  TITLE     Dynein light chain Tctex-type 1 modulates orexin signaling through
            its interaction with orexin 1 receptor
  JOURNAL   PLoS One 6 (10), e26430 (2011)
   PUBMED   22028875
REFERENCE   7  (bases 1 to 2153)
  AUTHORS   Lo,K.W., Kogoy,J.M. and Pfister,K.K.
  TITLE     The DYNLT3 light chain directly links cytoplasmic dynein to a
            spindle checkpoint protein, Bub3
  JOURNAL   J Biol Chem 282 (15), 11205-11212 (2007)
   PUBMED   17289665
  REMARK    GeneRIF: subpopulation of dynein, containing the DYNLT3 light
            chain, may be important for chromosome congression, in addition to
            having a role in the transport of checkpoint proteins from the
            kinetochore to the spindle pole
REFERENCE   8  (bases 1 to 2153)
  AUTHORS   Sacksteder,C.A., Qian,W.J., Knyushko,T.V., Wang,H., Chin,M.H.,
            Lacan,G., Melega,W.P., Camp,D.G. 2nd, Smith,R.D., Smith,D.J.,
            Squier,T.C. and Bigelow,D.J.
  TITLE     Endogenously nitrated proteins in mouse brain: links to
            neurodegenerative disease
  JOURNAL   Biochemistry 45 (26), 8009-8022 (2006)
   PUBMED   16800626
REFERENCE   9  (bases 1 to 2153)
  AUTHORS   Pfister,K.K., Fisher,E.M., Gibbons,I.R., Hays,T.S., Holzbaur,E.L.,
            McIntosh,J.R., Porter,M.E., Schroer,T.A., Vaughan,K.T.,
            Witman,G.B., King,S.M. and Vallee,R.B.
  TITLE     Cytoplasmic dynein nomenclature
  JOURNAL   J Cell Biol 171 (3), 411-413 (2005)
   PUBMED   16260502
REFERENCE   10 (bases 1 to 2153)
  AUTHORS   Li,K., Zhang,Q., Johnson,J.L. and Aguirre,G.D.
  TITLE     Comparative analysis, gene organization and expression of canine
            TCTE1L
  JOURNAL   Gene 303, 207-212 (2003)
   PUBMED   12559582
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL671118.30.
            
            On Apr 29, 2007 this sequence version replaced NM_025975.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK088277.1, BC030032.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-115               AL671118.30        167783-167897       c
            116-157             AL671118.30        165894-165935       c
            158-281             AL671118.30        161955-162078       c
            282-359             AL671118.30        161294-161371       c
            360-2153            AL671118.30        159184-160977       c
FEATURES             Location/Qualifiers
     source          1..2153
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 4.47 cM"
     gene            1..2153
                     /gene="Dynlt3"
                     /gene_synonym="2310075M16Rik; Tcte1l"
                     /note="dynein light chain Tctex-type 3"
                     /db_xref="GeneID:67117"
                     /db_xref="MGI:MGI:1914367"
     exon            1..115
                     /gene="Dynlt3"
                     /gene_synonym="2310075M16Rik; Tcte1l"
                     /inference="alignment:Splign:2.1.0"
     CDS             86..436
                     /gene="Dynlt3"
                     /gene_synonym="2310075M16Rik; Tcte1l"
                     /note="protein 91/23"
                     /codon_start=1
                     /product="dynein light chain Tctex-type 3"
                     /protein_id="NP_080251.3"
                     /db_xref="CCDS:CCDS30011.1"
                     /db_xref="GeneID:67117"
                     /db_xref="MGI:MGI:1914367"
                     /translation="MEGYQRPCDEVGFNADEAHNIVKECVDGVLGGNDYNENNINQWT
                     ASIVEQSITHLVKLGKAYKYIVTCAVVQRSPYGFHTASSCFWDTTSDGTCTIRWENRT
                     MNCIVNVFAVAIVL"
     exon            116..157
                     /gene="Dynlt3"
                     /gene_synonym="2310075M16Rik; Tcte1l"
                     /inference="alignment:Splign:2.1.0"
     exon            158..281
                     /gene="Dynlt3"
                     /gene_synonym="2310075M16Rik; Tcte1l"
                     /inference="alignment:Splign:2.1.0"
     exon            282..359
                     /gene="Dynlt3"
                     /gene_synonym="2310075M16Rik; Tcte1l"
                     /inference="alignment:Splign:2.1.0"
     exon            360..2153
                     /gene="Dynlt3"
                     /gene_synonym="2310075M16Rik; Tcte1l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaggcgggg cctccccaga ggccagtgcg cagctgagga cctggacaga aggcttgctc
       61 cgcccccagg actcagaaag ccaccatgga ggggtaccaa cggccctgcg atgaggttgg
      121 cttcaatgct gatgaagccc ataatatagt caaagagtgt gttgatggag ttttgggtgg
      181 taacgattat aatgagaata acatcaacca atggactgca agcatagtgg aacagtctat
      241 aacacatttg gtcaaactgg ggaaagctta caagtacatt gtgacctgtg cagtggtcca
      301 gaggagcccg tatggatttc acacagccag ctcctgtttt tgggatacaa catctgatgg
      361 aacctgtacc atcagatggg agaaccgtac catgaactgc atcgtgaatg tttttgcagt
      421 tgcgattgtc ctgtagcctg taatgcacta aaaaatgtgt tgggttaagg ccattaactt
      481 aagtttgtga gtgtatcctt tctaaaaaga gttacaacta cttattaatg tgctagatga
      541 caagtgtgca atatgcttca aagctatcaa cagagaactg aatattgtaa gcagaagtct
      601 aataggaagt tggcagaatt atctcgtatt ctatacagca tcatttaagg atataaaatg
      661 ttagttaaca attaatgcag aaatatggct gacctaaact tagaatcttc tacttataca
      721 agcctttcac tggcattatg ttcccccaga gatggggaaa tctatttaga tactaacatt
      781 atcattaact agaaaacaca acagggagaa atatatgaac aaaaactaca aggagaaatg
      841 cagagaaaat gacatgaagt acctaatacc tttctggttt aagttttatt cctttgttga
      901 attgcatata gtagttcata gagagtaatt tgacacacat acacccgccc catctaacta
      961 gttttctttt cctgagaact ggcaaatcca ttgatttttt ttttgtttgt tttaatgcca
     1021 gtttcttaca tttacacttg aggtggaatt aaatatgatc gaccagattt cctgggtgaa
     1081 caaaattagt aaagtatatg atcaacagta tatgactcag acaactgcct tacaatccat
     1141 tgcttccatg agagatgggc aggtacctat cggatgtgtg ctctgcatgt ttctctccag
     1201 gcagacagct cttaacgtgg tgttcacgtg gcattcacat ggcgttcacc tggcaggttg
     1261 gttttggcag ttattcagtt ggaaaaacca gtgtttatgt ttgagggaga ataaaagaaa
     1321 gaaaggaaaa gagtctggtc ctccgtggaa aattaaccag aaggagagcg ctaattggtg
     1381 acagaattat agatacagtt tttaagggtt gcttcccaga aagtaataca tcaaatatgc
     1441 aactcttact gaaaggcctt attagtagtc ttagctatac aatgataaat tttattgaat
     1501 tagtttcaac tgtgtgtgac taatttaaaa atacttatgt agagttagga caaatggggt
     1561 agaatataca ttaaaagtga acaatcatta gcaggttatc taatatctca gggcttatga
     1621 aatatagttc aatttattta aaaaaatcaa aaataaatat tcggatacac agctggccac
     1681 caaatgcaaa gtcagtctgc catttaacct tcaaaatgaa ctcgatttca catcttacca
     1741 ttgccacgca atccatgtaa acactggaat cacgtgccat tgaagtttta ggggaaggaa
     1801 acgtttagta gtaatggcaa caacattaag acaggatcct catatgagga ccatgtgcat
     1861 ggttgacatt ttgcagaata actctaatga caagaatgca aagatggggt ttaatgaggt
     1921 gacctgtagc tttggcacgt ccagagttct ttgtcattac ctttatgtta ctttatgctg
     1981 ctggctcttg taccttggga gattgtaaca gtgaccaaat tatctgtgca tttaaggctt
     2041 actctttgat tgttgttgtt gaaggctcat tttcaaagta tcaaatcata cctcgtgagc
     2101 ttgctatctg ctgtttctag ttaaaaatat aataaagact atcttattgt gct
//
