LOCUS       NM_025329                854 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus dynein light chain Tctex-type 2B (Dynlt2b), transcript
            variant 1, mRNA.
ACCESSION   NM_025329 NM_025552
VERSION     NM_025329.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 854)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 854)
  AUTHORS   Rutkowski,T.P., Purcell,R.H., Pollak,R.M., Grewenow,S.M.,
            Gafford,G.M., Malone,T., Khan,U.A., Schroeder,J.P., Epstein,M.P.,
            Bassell,G.J., Warren,S.T., Weinshenker,D., Caspary,T. and
            Mulle,J.G.
  TITLE     Behavioral changes and growth deficits in a CRISPR engineered mouse
            model of the schizophrenia-associated 3q29 deletion
  JOURNAL   Mol Psychiatry 26 (3), 772-783 (2021)
   PUBMED   30976085
REFERENCE   3  (bases 1 to 854)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 854)
  AUTHORS   Shimoda,Y., Okada,S., Yamada,E., Pessin,J.E. and Yamada,M.
  TITLE     Tctex1d2 Is a Negative Regulator of GLUT4 Translocation and Glucose
            Uptake
  JOURNAL   Endocrinology 156 (10), 3548-3558 (2015)
   PUBMED   26200093
  REMARK    GeneRIF: Tctex1d2 is a novel syntaxin 4 binding protein that
            functions as a negative regulator of GLUT4 plasma membrane
            translocation through inhibition of the Doc2b-syntaxin 4
            interaction
            Erratum:[Endocrinology. 2017 Apr 1;158(4):1048. doi:
            10.1210/en.2017-00141.. PMID: 28380631]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC059716.1 and BE990920.1.
            
            On Mar 19, 2018 this sequence version replaced NM_025329.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY703100.1, CB193829.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-631               BC059716.1         2-632
            632-854             BE990920.1         1-223               c
FEATURES             Location/Qualifiers
     source          1..854
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 22.69 cM"
     gene            1..854
                     /gene="Dynlt2b"
                     /gene_synonym="0610012D17Rik; 2410011K15Rik; Tctex1d2"
                     /note="dynein light chain Tctex-type 2B"
                     /db_xref="GeneID:66061"
                     /db_xref="MGI:MGI:1913311"
     exon            1..226
                     /gene="Dynlt2b"
                     /gene_synonym="0610012D17Rik; 2410011K15Rik; Tctex1d2"
                     /inference="alignment:Splign:2.1.0"
     exon            227..360
                     /gene="Dynlt2b"
                     /gene_synonym="0610012D17Rik; 2410011K15Rik; Tctex1d2"
                     /inference="alignment:Splign:2.1.0"
     exon            361..430
                     /gene="Dynlt2b"
                     /gene_synonym="0610012D17Rik; 2410011K15Rik; Tctex1d2"
                     /inference="alignment:Splign:2.1.0"
     exon            431..494
                     /gene="Dynlt2b"
                     /gene_synonym="0610012D17Rik; 2410011K15Rik; Tctex1d2"
                     /inference="alignment:Splign:2.1.0"
     exon            495..838
                     /gene="Dynlt2b"
                     /gene_synonym="0610012D17Rik; 2410011K15Rik; Tctex1d2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      611..616
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dynlt2b"
                     /gene_synonym="0610012D17Rik; 2410011K15Rik; Tctex1d2"
                     /note="hexamer: AACAAG"
     polyA_site      637
                     /gene="Dynlt2b"
                     /gene_synonym="0610012D17Rik; 2410011K15Rik; Tctex1d2"
                     /note="major polyA site"
     regulatory      813..818
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dynlt2b"
                     /gene_synonym="0610012D17Rik; 2410011K15Rik; Tctex1d2"
                     /note="hexamer: AATAAA"
     polyA_site      838
                     /gene="Dynlt2b"
                     /gene_synonym="0610012D17Rik; 2410011K15Rik; Tctex1d2"
ORIGIN      
        1 cacacgtcac gtgtgagacc cgttgcccta gcgacctgtg ccgggatctt cggagccgca
       61 accgaccaca cttccttcta gagatctgtt ggaccagacg cagggatatg gctgtgtcct
      121 tccgcggcct gtccttatcg gctcactccg agggcttgag tgaggtcgac aagaactcag
      181 gggagcctga gaacacctac attctgaggc ccattttcca gcaaaggttt agaccctctg
      241 tggttaaaga ctgcatccat actgtgctca aggaagaatt ggcaagtgct gaatattctc
      301 cagatgaaat gcctcaactc acaaaacgtc tatcagaaat gattaaagat aagctaaaag
      361 aattgggata tgaccggtat aaaatggtgg tgcaagtggt gattggagag cagaggggtg
      421 aaggagtatt catggctgct cgctgtttct gggatgcaga cacggacaac tacactcacg
      481 atgttttcat gaacgacagc ttattctgtg tggtggcagc atttgggtgt ttctactatt
      541 gaatcgttgg gaagtgtgac ttcaaggaac cttaactttt ttatattgtt aaatttcctg
      601 accaaataaa aacaagttgg cactttggta cctaaaatct gttaagttgt atatgtttaa
      661 atggcttgat tttattatgt tatctctgcc ctttctacat ttggaaaata tagagaaaaa
      721 ggggaaaatt cattttaata tgtcagatga ctagatactt gggtatattt tctattcatt
      781 gttccttata agatgtaaaa aaatatttat aaaataaatt gtgtgttttc accccttaaa
      841 aaaaaaaaaa aaaa
//
