LOCUS       NM_029297                515 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus dynein light chain roadblock-type 2 (Dynlrb2), mRNA.
ACCESSION   NM_029297
VERSION     NM_029297.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 515)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 515)
  AUTHORS   Pina,J.O., Raju,R., Roth,D.M., Winchester,E.W., Chattaraj,P.,
            Kidwai,F., Faucz,F.R., Iben,J., Mitra,A., Campbell,K., Fridell,G.,
            Esnault,C., Cotney,J.L., Dale,R.K. and D'Souza,R.N.
  TITLE     Multimodal spatiotemporal transcriptomic resolution of embryonic
            palate osteogenesis
  JOURNAL   Nat Commun 14 (1), 5687 (2023)
   PUBMED   37709732
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 515)
  AUTHORS   He,S., Gillies,J.P., Zang,J.L., Cordoba-Beldad,C.M., Yamamoto,I.,
            Fujiwara,Y., Grantham,J., DeSantis,M.E. and Shibuya,H.
  TITLE     Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate
            mitotic and male meiotic spindle bipolarity
  JOURNAL   Nat Commun 14 (1), 1715 (2023)
   PUBMED   36973253
  REMARK    GeneRIF: Distinct dynein complexes defined by DYNLRB1 and DYNLRB2
            regulate mitotic and male meiotic spindle bipolarity.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 515)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 515)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 515)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   7  (bases 1 to 515)
  AUTHORS   Alten,L., Schuster-Gossler,K., Beckers,A., Groos,S., Ulmer,B.,
            Hegermann,J., Ochs,M. and Gossler,A.
  TITLE     Differential regulation of node formation, nodal ciliogenesis and
            cilia positioning by Noto and Foxj1
  JOURNAL   Development 139 (7), 1276-1284 (2012)
   PUBMED   22357932
REFERENCE   8  (bases 1 to 515)
  AUTHORS   Beckers,A., Alten,L., Viebahn,C., Andre,P. and Gossler,A.
  TITLE     The mouse homeobox gene Noto regulates node morphogenesis,
            notochordal ciliogenesis, and left right patterning
  JOURNAL   Proc Natl Acad Sci U S A 104 (40), 15765-15770 (2007)
   PUBMED   17884984
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17554]
REFERENCE   9  (bases 1 to 515)
  AUTHORS   Pfister,K.K., Fisher,E.M., Gibbons,I.R., Hays,T.S., Holzbaur,E.L.,
            McIntosh,J.R., Porter,M.E., Schroer,T.A., Vaughan,K.T.,
            Witman,G.B., King,S.M. and Vallee,R.B.
  TITLE     Cytoplasmic dynein nomenclature
  JOURNAL   J Cell Biol 171 (3), 411-413 (2005)
   PUBMED   16260502
REFERENCE   10 (bases 1 to 515)
  AUTHORS   Nikulina,K., Patel-King,R.S., Takebe,S., Pfister,K.K. and King,S.M.
  TITLE     The Roadblock light chains are ubiquitous components of cytoplasmic
            dynein that form homo- and heterodimers
  JOURNAL   Cell Motil Cytoskeleton 57 (4), 233-245 (2004)
   PUBMED   14752807
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK005789.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005789.1, BY705942.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..515
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 63.07 cM"
     gene            1..515
                     /gene="Dynlrb2"
                     /gene_synonym="1700009A04Rik; Dncl2b; DNLC2B"
                     /note="dynein light chain roadblock-type 2"
                     /db_xref="GeneID:75465"
                     /db_xref="MGI:MGI:1922715"
     exon            1..35
                     /gene="Dynlrb2"
                     /gene_synonym="1700009A04Rik; Dncl2b; DNLC2B"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..323
                     /gene="Dynlrb2"
                     /gene_synonym="1700009A04Rik; Dncl2b; DNLC2B"
                     /note="dynein, cytoplasmic, light chain 2B; dynein,
                     cytoplasmic, light polypeptide 2B; dynein light chain 2B,
                     cytoplasmic"
                     /codon_start=1
                     /product="dynein light chain roadblock-type 2"
                     /protein_id="NP_083573.1"
                     /db_xref="CCDS:CCDS40487.1"
                     /db_xref="GeneID:75465"
                     /db_xref="MGI:MGI:1922715"
                     /translation="MTEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAG
                     LLHQLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPDKEYLLIVIQNPCE"
     exon            36..111
                     /gene="Dynlrb2"
                     /gene_synonym="1700009A04Rik; Dncl2b; DNLC2B"
                     /inference="alignment:Splign:2.1.0"
     exon            112..279
                     /gene="Dynlrb2"
                     /gene_synonym="1700009A04Rik; Dncl2b; DNLC2B"
                     /inference="alignment:Splign:2.1.0"
     exon            280..515
                     /gene="Dynlrb2"
                     /gene_synonym="1700009A04Rik; Dncl2b; DNLC2B"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      515
                     /gene="Dynlrb2"
                     /gene_synonym="1700009A04Rik; Dncl2b; DNLC2B"
                     /note="putative"
ORIGIN      
        1 agacttgagc caggagctgt cccacaggcg cgatgacaga agtggaggaa accctcaaga
       61 gaatccagag tcacaaaggg gtcatcggaa cgatggtggt caatgcagaa ggcattccaa
      121 tccgaacaac cctggacaac tccacaacgg ttcagtatgc gggtcttctc caccagctga
      181 ccatgaaagc caagagcaca gtcagggata ttgaccccca gaacgacctg acttttctta
      241 ggatcagatc gaagaaacat gaaatcatgg tagccccaga taaggaatat cttctgattg
      301 tcattcagaa cccatgtgag tagacctgct gtgaccaacc ctgtcctcct gacgatacct
      361 ggaagccctt ccctccacga atccatgata ttgtaccctg actgagtcca gagatgtgtt
      421 ctcctgtttt gacaatggaa ctgcactact tgcttcccta agtccccttt gaattgtgat
      481 cttgtacttt tgctgtataa taaaaaaatt ctgct
//
