LOCUS       NM_001418869            1169 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus dual specificity phosphatase 29 (Dusp29), transcript
            variant 2, mRNA.
ACCESSION   NM_001418869 XM_006519217
VERSION     NM_001418869.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1169)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1169)
  AUTHORS   Cooper,L.M., West,R.C., Hayes,C.S. and Waddell,D.S.
  TITLE     Dual-specificity phosphatase 29 is induced during neurogenic
            skeletal muscle atrophy and attenuates glucocorticoid receptor
            activity in muscle cell culture
  JOURNAL   Am J Physiol Cell Physiol 319 (2), C441-C454 (2020)
   PUBMED   32639872
REFERENCE   3  (bases 1 to 1169)
  AUTHORS   Geng,T., Liu,Y., Xu,Y., Jiang,Y., Zhang,N., Wang,Z.,
            Carmichael,G.G., Taylor,H.S., Li,D. and Huang,Y.
  TITLE     H19 lncRNA Promotes Skeletal Muscle Insulin Sensitivity in Part by
            Targeting AMPK
  JOURNAL   Diabetes 67 (11), 2183-2198 (2018)
   PUBMED   30201684
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC151533.3 and AC148978.3.
            
            On Mar 24, 2023 this sequence version replaced XM_006519217.5.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384,
                              SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-99                AC151533.3         128531-128629
            100-324             AC151533.3         128750-128974
            325-545             AC151533.3         145019-145239
            546-1169            AC148978.3         3843-4466
FEATURES             Location/Qualifiers
     source          1..1169
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 11.82 cM"
     gene            1..1169
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
                     /note="dual specificity phosphatase 29"
                     /db_xref="GeneID:435391"
                     /db_xref="MGI:MGI:3647127"
     exon            1..99
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
                     /inference="alignment:Splign:2.1.0"
     exon            100..324
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..775
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
                     /EC_number="3.1.3.16"
                     /EC_number="3.1.3.48"
                     /note="dual specificity phosphatase DUPD1; dual
                     specificity phosphatase and pro isomerase domain
                     containing 1"
                     /codon_start=1
                     /product="dual specificity phosphatase 29"
                     /protein_id="NP_001405798.1"
                     /db_xref="GeneID:435391"
                     /db_xref="MGI:MGI:3647127"
                     /translation="MASGDTKTSVKHAHLCAERLSVREEEGDAEDYCTPGAFELERLF
                     WKGSPQYTHVNEVWPRLHIGDEATALDRYGLQKAGFTHVLNAAHGRWNVDTGPDYYRD
                     MAIEYHGVEADDVPTFDLSIFFYSAAAFIDSALRDDHSKILVHCAMGRSRSATLVLAY
                     LMIHKNMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQLVKQRRQAGPGDSDLGL"
     exon            325..545
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
                     /inference="alignment:Splign:2.1.0"
     exon            546..1169
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1086..1091
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
                     /note="hexamer: ATTAAA"
     polyA_site      1106
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
                     /note="major polyA site"
     regulatory      1124..1129
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
                     /note="hexamer: TATAAA"
     regulatory      1140..1145
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
                     /note="hexamer: AATAGA"
     polyA_site      1143
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
     polyA_site      1169
                     /gene="Dusp29"
                     /gene_synonym="Dupd1; EG435391"
                     /note="major polyA site"
ORIGIN      
        1 gcttacgctt cctgagggtt tgctgtgtga acactggaat gttggggagt gtcgattaac
       61 tgtcatcctg gcctttctca cttacccgtg tgtcttgaga aaggaaagaa cctcccttgg
      121 ctccaaaatg gcatcaggag atacaaagac aagcgtcaaa catgcccacc tctgtgctga
      181 gaggctgtcc gtgcgggagg aggagggaga tgctgaggac tactgtaccc ctggagcctt
      241 cgagctggag cgtctcttct ggaagggcag tccccagtat acacacgtca atgaggtctg
      301 gcctcggctc cacattggtg atgaggccac ggcgctggac cgctatgggc tgcagaaggc
      361 gggtttcacg cacgtgctga acgcggcgca cggccgctgg aatgtggaca ccgggccgga
      421 ctactaccga gacatggcca tcgagtacca cggcgtcgag gccgacgacg tgcccacctt
      481 cgacctcagc atctttttct actccgctgc ggccttcatc gactcggcac tccgagatga
      541 ccacagtaag atcctggttc actgtgccat gggccgaagt cggtcagcaa ctctggtcct
      601 ggcctacctg atgatccaca agaacatgac tttggtggac gccattcaac aagtggctaa
      661 gaaccgctgt gtcctgccca accggggctt cttgaagcaa ctccgagagc tggacaagca
      721 gctggtgaag cagcggcgac aggccgggcc aggggacagt gacctagggc tgtagggggc
      781 ctcctcagag aggatcagag accctggcac ccagagcaga aggctgaagc acgtctgcaa
      841 ggaggctttg gtgggcaggg agatgagaca gtgaaaccaa aggctgggcg cagcagggag
      901 gatgcccgct gtctcctcca gtctagttct ttgcctcatg gtaggccaag tcagctgcag
      961 ggggatctgg gtaaggaaaa ggtaccgctc tccacaatct cctgtcttta agttggaagc
     1021 aaaaaaaggt ttcctttgtt tgggctgttt tttgttttgt tttaatgtgt gggtactgtg
     1081 ttgtgattaa atgcttggct ctgaaaggga aaaatcatgt tattataaaa agataaaaaa
     1141 atagagcttg attttttttt tcaaccaca
//
