LOCUS       NM_001374075            1321 bp    mRNA    linear   ROD 08-FEB-2025
DEFINITION  Mus musculus dual specificity phosphatase 13B (Dusp13b), transcript
            variant 3, mRNA.
ACCESSION   NM_001374075 XM_011245080
VERSION     NM_001374075.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1321)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1321)
  AUTHORS   Celaya,A.M., Sanchez-Perez,I., Bermudez-Munoz,J.M., Rodriguez-de la
            Rosa,L., Pintado-Berninches,L., Perona,R., Murillo-Cuesta,S. and
            Varela-Nieto,I.
  TITLE     Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1)
            accelerates progressive hearing loss
  JOURNAL   Elife 8, e39159 (2019)
   PUBMED   30938680
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1321)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 1321)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 1321)
  AUTHORS   Roma-Mateo,C., Rios,P., Tabernero,L., Attwood,T.K. and Pulido,R.
  TITLE     A novel phosphatase family, structurally related to
            dual-specificity phosphatases, that displays unique amino acid
            sequence and substrate specificity
  JOURNAL   J Mol Biol 374 (4), 899-909 (2007)
   PUBMED   17976645
REFERENCE   6  (bases 1 to 1321)
  AUTHORS   Chen,H.H., Luche,R., Wei,B. and Tonks,N.K.
  TITLE     Characterization of two distinct dual specificity phosphatases
            encoded in alternative open reading frames of a single gene located
            on human chromosome 10q22.2
  JOURNAL   J Biol Chem 279 (40), 41404-41413 (2004)
   PUBMED   15252030
  REMARK    GeneRIF: expression of both MDSP and TMDP proteins was markedly
            increased at the 3rd week after birth and continued to increase
            gradually into adulthood, implying that the physiological functions
            of both DSPs are specific to the mature/late-developing organs
REFERENCE   7  (bases 1 to 1321)
  AUTHORS   Almind,K., Kulkarni,R.N., Lannon,S.M. and Kahn,C.R.
  TITLE     Identification of interactive loci linked to insulin and leptin in
            mice with genetic insulin resistance
  JOURNAL   Diabetes 52 (6), 1535-1543 (2003)
   PUBMED   12765967
REFERENCE   8  (bases 1 to 1321)
  AUTHORS   Aoki,N., Aoyama,K., Nagata,M. and Matsuda,T.
  TITLE     A growing family of dual specificity phosphatases with low
            molecular masses
  JOURNAL   J Biochem 130 (1), 133-140 (2001)
   PUBMED   11432789
REFERENCE   9  (bases 1 to 1321)
  AUTHORS   Nakamura,K., Shima,H., Watanabe,M., Haneji,T. and Kikuchi,K.
  TITLE     Molecular cloning and characterization of a novel dual-specificity
            protein phosphatase possibly involved in spermatogenesis
  JOURNAL   Biochem J 344 Pt 3 (Pt 3), 819-825 (1999)
   PUBMED   10585869
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC151533.3.
            
            On Sep 10, 2019 this sequence version replaced XM_011245080.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.90104.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-469               AC151533.3         90356-90824
            470-643             AC151533.3         91577-91750
            644-864             AC151533.3         96738-96958
            865-1321            AC151533.3         98003-98459
FEATURES             Location/Qualifiers
     source          1..1321
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 11.85 cM"
     gene            1..1321
                     /gene="Dusp13b"
                     /gene_synonym="Dusp13; DUSP13A; Gm1203; LMW-DSP6; MDSP;
                     TMDP; TS-DSP6"
                     /note="dual specificity phosphatase 13B"
                     /db_xref="GeneID:27389"
                     /db_xref="MGI:MGI:1351599"
     exon            1..469
                     /gene="Dusp13b"
                     /gene_synonym="Dusp13; DUSP13A; Gm1203; LMW-DSP6; MDSP;
                     TMDP; TS-DSP6"
                     /inference="alignment:Splign:2.1.0"
     exon            470..643
                     /gene="Dusp13b"
                     /gene_synonym="Dusp13; DUSP13A; Gm1203; LMW-DSP6; MDSP;
                     TMDP; TS-DSP6"
                     /inference="alignment:Splign:2.1.0"
     exon            644..864
                     /gene="Dusp13b"
                     /gene_synonym="Dusp13; DUSP13A; Gm1203; LMW-DSP6; MDSP;
                     TMDP; TS-DSP6"
                     /inference="alignment:Splign:2.1.0"
     exon            865..1321
                     /gene="Dusp13b"
                     /gene_synonym="Dusp13; DUSP13A; Gm1203; LMW-DSP6; MDSP;
                     TMDP; TS-DSP6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1299..1304
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dusp13b"
                     /gene_synonym="Dusp13; DUSP13A; Gm1203; LMW-DSP6; MDSP;
                     TMDP; TS-DSP6"
                     /note="hexamer: AATAAA"
     polyA_site      1321
                     /gene="Dusp13b"
                     /gene_synonym="Dusp13; DUSP13A; Gm1203; LMW-DSP6; MDSP;
                     TMDP; TS-DSP6"
                     /note="major polyA site"
ORIGIN      
        1 gctttaggac tgttccactc agcctgcccc tgcacctagt cccccattcc tggccccaga
       61 ccatgcccta ggtaggtggc aggccactca gcctgccaga gaggtcacag agggggatga
      121 gggagaaagg ccggccctct cttccaccca gctcatcatc cactggctgg gtgagtgtgg
      181 ccaagccagt ggcctcctgg gtgcccatct ctttttctgg ttttggcagt gcctgccaga
      241 gggaaaaggc attctaccca gtctgtacct actcgagtta ctctttgagg ggaccagggg
      301 tagttgacca aggtaggttc cccttccctc taaggtacca ggctcaggtt ctggtgcctc
      361 tgacacctca gctctgcaag ggcccagatg gactaagcca gatgactcca gacataaccc
      421 actccttccg ggtgaggcct gtacaggtgt actggcctga accacaagga atggactcgc
      481 tacagaagca ggaacttcgg aggccaaaga ttcatggggc agtccaggtg tccccctacc
      541 agccacccac actggcctct ctgcagcgat tgctgtgggt ccgtcggact gccacactga
      601 cccacatcaa tgaggtctgg cccaaccttt tcttgggaga tgcgtatgct gccagagaca
      661 agggtcgtct aatccagctg ggcattaccc atgttgtgaa tgtggctgcg ggcaagttcc
      721 aggtggacac aggtgccaag ttctaccgtg gaacacctct ggagtactat ggcattgagg
      781 ctgatgacaa ccccttcttt gacctcagcg tccactttct gcctgttgct cgttacatca
      841 gagatgccct caatattccc cgaagccgag tgctggtcca ctgcgctatg ggggtgagtc
      901 gctctgccac aattgtcttg gccttcctca tgatcttcga gaacatgaca ctggtagatg
      961 ccatccagac ggtgcaggcc caccgagata tctgtcccaa ctcaggcttc ctccgacagc
     1021 tccaggttct ggacaacagg ctgaggcggg aaacaggaag actctgaatt agggagcacc
     1081 tgaggccctg acccctccat ccagcgtggc ctaacctgac ctacctggcc ctgggaatgg
     1141 tagcctctgc tgtttccaga gatcctgaga tggcaccagc aagtcagggc tccgctgagg
     1201 cagaggcagg gtgggctggg tggcacccct cagcaagtgg agtcccctga cacagtacag
     1261 aaactcttta tacagaagaa atttcagact gtctctataa taaaaggttc atcataataa
     1321 a
//
