LOCUS       NM_013642               1952 bp    mRNA    linear   ROD 01-OCT-2024
DEFINITION  Mus musculus dual specificity phosphatase 1 (Dusp1), mRNA.
ACCESSION   NM_013642
VERSION     NM_013642.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1952)
  AUTHORS   Gao,J., Wang,Z., Lin,S., Tian,Y., Wu,H., Li,Z. and Liu,F.
  TITLE     CCR7/DUSP1 signaling Axis mediates iCAF to regulates head and neck
            squamous cell carcinoma growth
  JOURNAL   Cell Signal 122, 111305 (2024)
   PUBMED   39067836
  REMARK    GeneRIF: CCR7/DUSP1 signaling Axis mediates iCAF to regulates head
            and neck squamous cell carcinoma growth.
REFERENCE   2  (bases 1 to 1952)
  AUTHORS   Huang,S., Reed,C., Ilsley,M., Magor,G., Tallack,M., Landsberg,M.,
            Mitchell,H., Gillinder,K. and Perkins,A.
  TITLE     Mutations in linker-2 of KLF1 impair expression of membrane
            transporters and cytoskeletal proteins causing hemolysis
  JOURNAL   Nat Commun 15 (1), 7019 (2024)
   PUBMED   39147774
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1952)
  AUTHORS   Kesarwani,M., Kincaid,Z., Azhar,M. and Azam,M.
  TITLE     Enhanced MAPK signaling induced by CSF3R mutants confers dependence
            to DUSP1 for leukemic transformation
  JOURNAL   Blood Adv 8 (11), 2765-2776 (2024)
   PUBMED   38531054
  REMARK    GeneRIF: Enhanced MAPK signaling induced by CSF3R mutants confers
            dependence to DUSP1 for leukemic transformation.
REFERENCE   4  (bases 1 to 1952)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 1952)
  AUTHORS   Walter,M.N., Montoya-Durango,D., Rodriguez,W., Wang,Y., Zhang,J.,
            Chariker,J.H., Rouchka,E.C., Maldonado,C., Bennett,A.,
            McClain,C.J., Barve,S. and Gobejishvili,L.
  TITLE     Hepatocyte-specific mitogen-activated protein kinase phosphatase 1
            in sexual dimorphism and susceptibility to alcohol induced liver
            injury
  JOURNAL   Front Immunol 15, 1316228 (2024)
   PUBMED   38370409
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1952)
  AUTHORS   Schwan,W.R., Kugler,S., Schuller,S., Kopecko,D.J. and Goebel,W.
  TITLE     Detection and characterization by differential PCR of host
            eukaryotic cell genes differentially transcribed following uptake
            of intracellular bacteria
  JOURNAL   Infect Immun 64 (1), 91-99 (1996)
   PUBMED   8557379
REFERENCE   7  (bases 1 to 1952)
  AUTHORS   Sun,H., Charles,C.H., Lau,L.F. and Tonks,N.K.
  TITLE     MKP-1 (3CH134), an immediate early gene product, is a dual
            specificity phosphatase that dephosphorylates MAP kinase in vivo
  JOURNAL   Cell 75 (3), 487-493 (1993)
   PUBMED   8221888
REFERENCE   8  (bases 1 to 1952)
  AUTHORS   Carrasco,D. and Bravo,R.
  TITLE     Expression of the nontransmembrane tyrosine phosphatase gene erp
            during mouse organogenesis
  JOURNAL   Cell Growth Differ 4 (10), 849-859 (1993)
   PUBMED   8274454
REFERENCE   9  (bases 1 to 1952)
  AUTHORS   Noguchi,T., Metz,R., Chen,L., Mattei,M.G., Carrasco,D. and Bravo,R.
  TITLE     Structure, mapping, and expression of erp, a growth
            factor-inducible gene encoding a nontransmembrane protein tyrosine
            phosphatase, and effect of ERP on cell growth
  JOURNAL   Mol Cell Biol 13 (9), 5195-5205 (1993)
   PUBMED   8355678
REFERENCE   10 (bases 1 to 1952)
  AUTHORS   Charles,C.H., Abler,A.S. and Lau,L.F.
  TITLE     cDNA sequence of a growth factor-inducible immediate early gene and
            characterization of its encoded protein
  JOURNAL   Oncogene 7 (1), 187-190 (1992)
   PUBMED   1741163
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK159251.1 and U19515.1.
            
            On Jan 3, 2009 this sequence version replaced NM_013642.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC006967.1, AK152324.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1939              AK159251.1         2-1940
            1940-1952           U19515.1           360-372
FEATURES             Location/Qualifiers
     source          1..1952
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 13.28 cM"
     gene            1..1952
                     /gene="Dusp1"
                     /gene_synonym="3CH134; erp; mkp-1; MKP1; Ptpn16"
                     /note="dual specificity phosphatase 1"
                     /db_xref="GeneID:19252"
                     /db_xref="MGI:MGI:105120"
     exon            1..516
                     /gene="Dusp1"
                     /gene_synonym="3CH134; erp; mkp-1; MKP1; Ptpn16"
                     /inference="alignment:Splign:2.1.0"
     exon            517..662
                     /gene="Dusp1"
                     /gene_synonym="3CH134; erp; mkp-1; MKP1; Ptpn16"
                     /inference="alignment:Splign:2.1.0"
     exon            663..882
                     /gene="Dusp1"
                     /gene_synonym="3CH134; erp; mkp-1; MKP1; Ptpn16"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1942
                     /gene="Dusp1"
                     /gene_synonym="3CH134; erp; mkp-1; MKP1; Ptpn16"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1919..1924
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dusp1"
                     /gene_synonym="3CH134; erp; mkp-1; MKP1; Ptpn16"
                     /note="hexamer: AATAAA"
     polyA_site      1942
                     /gene="Dusp1"
                     /gene_synonym="3CH134; erp; mkp-1; MKP1; Ptpn16"
                     /note="major polyA site"
ORIGIN      
        1 agtgaaggac tggcgggagg aaagcgcggt gaagccagat taggagcagc gagcacttgg
       61 ggacttaggg ccacaggaca ccgcacaaga tcgaccgact ttttctggag aaccgcagaa
      121 cgggcacgct ggggtcgctg gggctggcca tggtgatgga ggtgggcatc ctggacgccg
      181 gggggctgcg cgcgctgctg cgagagggcg ccgcgcagtg cctgttgttg gattgtcgct
      241 ccttcttcgc tttcaacgcc ggccacatcg cgggctcagt gaacgtgcgc ttcagcacca
      301 tcgtgcggcg ccgcgccaag ggcgccatgg gcctggagca tatcgtgccc aacgctgaac
      361 tgcgtggccg cctgctggcc ggagcctacc acgccgtggt gctgctggac gagcgcagcg
      421 cctccctgga cggcgccaag cgcgacggca ccctggccct ggccgcgggc gcgctctgcc
      481 gagaggcgcg ctccactcaa gtcttctttc tccaaggagg atatgaagcg ttttcggctt
      541 cctgccctga gctgtgcagc aaacagtcca cccccacggg gctcagcctc cccctgagta
      601 ctagtgtgcc tgacagtgca gaatccggat gcagctcctg tagtacccct ctctacgatc
      661 aggggggccc agtggagatc ctgtccttcc tgtacctggg cagtgcctat cacgcttctc
      721 ggaaggatat gcttgacgcc ttgggcatca ccgccttgat caacgtctca gccaattgtc
      781 ctaaccactt tgagggtcac taccagtaca agagcatccc tgtggaggac aaccacaagg
      841 cagacatcag ctcctggttc aacgaggcta ttgacttcat agactccatc aaggatgctg
      901 gagggagagt gtttgttcat tgccaggccg gcatctcccg gtcagccacc atctgccttg
      961 cttacctcat gaggactaac cgggtaaagc tggacgaggc ctttgagttt gtgaagcaga
     1021 ggcggagtat catctccccg aacttcagct tcatgggcca gctgctgcag tttgagtccc
     1081 aagtgctagc ccctcactgc tctgctgaag ctgggagccc tgccatggct gtccttgacc
     1141 ggggcacctc tactaccaca gtcttcaact tccctgtttc catccccgtc caccccacga
     1201 acagtgccct gaactacctt aaaagcccca tcaccacctc tccaagctgc tgaagggcaa
     1261 ggggaggtgt ggagtttcac ttgccaccgg gtcgccactc ctcctgtggg aggagcaatg
     1321 caataactct gggagaggct catgggagct ggtccttatt tatttaacac ccccctcacc
     1381 ccccaactcc tcctgagttc cactgagttc ctaagcagtc acaacaatga cttgaccgca
     1441 agacatttgc tgaactcggc acattcggga ccaatatatt gtgggtacat caagtccctc
     1501 tgacaaaaca gggcagaaga gaaaggactc tgtttgaggc agtttcttcg cttgcctgtt
     1561 tttttttttc tagaaacttc atgcttgaca cacccaccag tattaaccat tcccgatgac
     1621 atgcgcgtat gagagttttt acctttattt atttttgtgt aggtcggtgg tctgccttca
     1681 caaatgtcat tgtctactca tagaagaacc aaatacctca attttgtgtt tgcgtactgt
     1741 actatcttgt aaatagaccc agagcaggtt tgctttcggc actgacagac aaagccagtg
     1801 taggtttgta gctttcagtt atcgacagtt gtatgtttgt ttatttatga tctgaagtaa
     1861 tatatttctt cttctgagaa gacattttgt tactgggatg acttttttta tacaacagaa
     1921 taaattatga cgtttctatt gaaaaaaaaa aa
//
