LOCUS       NM_028002               1782 bp    mRNA    linear   ROD 27-JUL-2024
DEFINITION  Mus musculus dihydrouridine synthase 4 like (Dus4l), transcript
            variant 1, mRNA.
ACCESSION   NM_028002
VERSION     NM_028002.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1782)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC119950.14.
            
            On Mar 14, 2023 this sequence version replaced NM_028002.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.3588842.1, AK010138.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               AC119950.14        121960-122105       c
            147-297             AC119950.14        119561-119711       c
            298-419             AC119950.14        116036-116157       c
            420-537             AC119950.14        113891-114008       c
            538-660             AC119950.14        110034-110156       c
            661-887             AC119950.14        108772-108998       c
            888-1782            AC119950.14        107320-108214       c
FEATURES             Location/Qualifiers
     source          1..1782
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 13.68 cM"
     gene            1..1782
                     /gene="Dus4l"
                     /gene_synonym="2310069P03Rik; 2700089B10Rik; Pp35"
                     /note="dihydrouridine synthase 4 like"
                     /db_xref="GeneID:71916"
                     /db_xref="MGI:MGI:1919166"
     exon            1..146
                     /gene="Dus4l"
                     /gene_synonym="2310069P03Rik; 2700089B10Rik; Pp35"
                     /inference="alignment:Splign:2.1.0"
     exon            147..297
                     /gene="Dus4l"
                     /gene_synonym="2310069P03Rik; 2700089B10Rik; Pp35"
                     /inference="alignment:Splign:2.1.0"
     CDS             182..1156
                     /gene="Dus4l"
                     /gene_synonym="2310069P03Rik; 2700089B10Rik; Pp35"
                     /EC_number="1.3.1.90"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="tRNA-dihydrouridine(20a/20b) synthase
                     [NAD(P)+]-like isoform 1"
                     /protein_id="NP_082278.1"
                     /db_xref="CCDS:CCDS25865.1"
                     /db_xref="GeneID:71916"
                     /db_xref="MGI:MGI:1919166"
                     /translation="MRSDSLPTTICQERKKDPIEMFHSGQLVKVCAPMVRYSKLAFRT
                     LVRKYSCDLCYTPMIIAADFVRSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAALL
                     VCPYANGIDINCGCPQRWAMADGYGACLINKPELVHDMVRQVRNRVESPRFSVSIKIR
                     IHDDLARTIDLCRKAEATGVSWITVHGRTVEERHQPVHYDAIKMIKENVSIPIVANGD
                     IRSLKEAENVWQMTGTDGVMVARGLLTNPAMFAGYEETPLKCIWDWVDISLELGTPFM
                     CFHQHLMYMMEKITSRQEKRVFNALSSTSAVLDYLTDHYGDESLSKSL"
     exon            298..419
                     /gene="Dus4l"
                     /gene_synonym="2310069P03Rik; 2700089B10Rik; Pp35"
                     /inference="alignment:Splign:2.1.0"
     exon            420..537
                     /gene="Dus4l"
                     /gene_synonym="2310069P03Rik; 2700089B10Rik; Pp35"
                     /inference="alignment:Splign:2.1.0"
     exon            538..660
                     /gene="Dus4l"
                     /gene_synonym="2310069P03Rik; 2700089B10Rik; Pp35"
                     /inference="alignment:Splign:2.1.0"
     exon            661..887
                     /gene="Dus4l"
                     /gene_synonym="2310069P03Rik; 2700089B10Rik; Pp35"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1782
                     /gene="Dus4l"
                     /gene_synonym="2310069P03Rik; 2700089B10Rik; Pp35"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1761..1766
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dus4l"
                     /gene_synonym="2310069P03Rik; 2700089B10Rik; Pp35"
                     /note="hexamer: AATAAA"
     polyA_site      1782
                     /gene="Dus4l"
                     /gene_synonym="2310069P03Rik; 2700089B10Rik; Pp35"
                     /note="major polyA site"
ORIGIN      
        1 gcagaatcaa ggcgccgccc cacctgcccg gcccgggttg cgtttgggaa cctaagtact
       61 acaatcctac gtgcaaggaa agacaggtcg ccgccggggc cttctcccat tccgctccgg
      121 acgcagccac cgcgccgatc tccaacactg tctttttcag acttgaaact aacctgtaca
      181 catgagaagt gactccttac caaccacaat atgtcaagaa agaaaaaaag acccgataga
      241 aatgtttcat tctggacagc tggtaaaagt ctgtgccccg atggttcgat attcaaagtt
      301 agcttttaga acattagtaa gaaaatactc ttgtgacctg tgttacacac caatgataat
      361 tgctgctgat tttgtcagat ctataaaagc cagagacagt gaatttacca caaaccaagg
      421 tgattgcccg ttgattgttc agtttgctgc taatgatgca agacttttat ctgatgctgc
      481 cctgctagtc tgtccctatg caaatggaat agatattaac tgtggttgcc ctcagaggtg
      541 ggcgatggcg gacggttatg gagcttgctt gatcaacaag ccagagcttg ttcacgatat
      601 ggtgagacaa gtgagaaatc gggtggaaag cccaaggttt tcagtttcca ttaagataag
      661 gatccacgat gacctggcaa gaaccataga tctttgccgg aaggctgaag caacaggagt
      721 gtcctggatt acagttcatg gaaggacagt tgaagaaaga caccagccag tccactacga
      781 tgccattaaa atgataaagg aaaatgtgtc tatacccata gttgctaatg gagacataag
      841 aagcttaaaa gaagcagaaa atgtgtggca gatgactggg acagatggtg tgatggttgc
      901 aagaggactt ttaacaaacc cagctatgtt tgctggatat gaagaaaccc cactgaaatg
      961 tatctgggac tgggttgaca tctctcttga acttggaact ccttttatgt gcttccatca
     1021 gcatctgatg tacatgatgg aaaagataac gtcaaggcag gagaagagag tatttaatgc
     1081 cttgtcaagc acatcagcag tcctggacta ccttacggac cattatggtg atgagtcgct
     1141 ttctaaatct ttgtagtagg tacttcttac ctacatggaa ccacatgagg ttacagcctc
     1201 gtatttcttt taagtctatg gcttttaaca tcagtacaac agcaatccct ggggccagac
     1261 atggcggcac atgtctttta tccagctact cagaaaacta aaggaagagg tttggaaatt
     1321 ctaggccagc aaaactttat ctgaaagaat aaacggaact tttccataac caagaactca
     1381 aacctgggac tgtagagatg gctcaccagt taaaacctcg ctgctcttct acaggacctg
     1441 agctccagtt ccaggggatt caacaggctt ttcaggcctc ctcaggcacc agctaagcac
     1501 aatgtgtaca gacagccatg caagcaaaac attcatacac ataaaactag caacaatggc
     1561 cacaaaaatc cgcccggtac tccgtcctca tggattcagt agattgtgag cagacccaga
     1621 agttgtaaag aactccggag ttttgaccat ccaataatcc cagatcaaat attgaaaacc
     1681 tctgcttcta atctttatgg gtgtgcggga tgggtgggga tgggagtttt actaaaggta
     1741 ttctgttttt aagtgtttta aataaaactt ttctaatagc aa
//
