LOCUS       NM_144858               2321 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus dihydrouridine synthase 3 like (Dus3l), transcript
            variant 1, mRNA.
ACCESSION   NM_144858 XM_977990 XM_978022 XM_978061 XM_978098 XM_978142
            XM_978180 XM_978219 XM_978263
VERSION     NM_144858.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2321)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   2  (bases 1 to 2321)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY295359.1, DV647483.1, CK387816.1, CX201215.1, BM224665.2,
            AA123957.1 and BI133429.1.
            
            On Aug 1, 2009 this sequence version replaced NM_144858.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660811.184828.1, AY040840.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                BY295359.1         2-22
            22-725              DV647483.1         1-704
            726-1235            CK387816.1         13-522
            1236-1614           CX201215.1         239-617
            1615-2051           BM224665.2         1-437               c
            2052-2298           AA123957.1         346-592
            2299-2321           BI133429.1         1-23                c
FEATURES             Location/Qualifiers
     source          1..2321
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 29.5 cM"
     gene            1..2321
                     /gene="Dus3l"
                     /note="dihydrouridine synthase 3 like"
                     /db_xref="GeneID:224907"
                     /db_xref="MGI:MGI:2147092"
     exon            1..191
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..2019
                     /gene="Dus3l"
                     /EC_number="1.3.1.89"
                     /note="isoform 1 is encoded by transcript variant 1;
                     putative zinc finger protein MA23; mRNA-dihydrouridine
                     synthase DUS3L"
                     /codon_start=1
                     /product="tRNA-dihydrouridine(47) synthase
                     [NAD(P)(+)]-like isoform 1"
                     /protein_id="NP_659107.2"
                     /db_xref="CCDS:CCDS28914.1"
                     /db_xref="GeneID:224907"
                     /db_xref="MGI:MGI:2147092"
                     /translation="MAETAAESGGGGDSGVGACERGVAPIKAQYRTTKERFHEYLDGD
                     KQEGACQEVPTGDPAEPGAKRIRLEDGQENGKTEVAIESRERQVPKRARGQNKSRPHV
                     KPAHYDKDRLCPSFLQEPATPCAFGDRCRFLHDVGRYLETKPADLGPRCVLFETFGRC
                     PFSMTCRFAGAHLGPEGQNLVQEEVVARCAQLPSVRNGLDRALQQQLRKRQVCFERAE
                     QALNRLTQSPMPTVVPETTVAMATPKQNSCHAQLDTVGGAGTPQSSPVPTCGPLTDED
                     VIRLRPCEKKRLDISGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQM
                     SEWALLKRHPCEDIFGVQLEGAFPDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKKG
                     GGCALMNRSAKFQQIVRGVNEVLDVPLTVKMRTGVQERVSLAHRLLPELRDWGVALVT
                     LHGRSREQRYTRLADWPYIEQCAKVASPMPLFGNGDILSFEDANCAMQTGVAGIMVAR
                     GALLKPWLFTEIKEQRHWDISSSERLDILRDFTHYGLEHWGSDTQGVERTRRFLLEWL
                     SFLCRYVPVGLLERPPQRINERPPYYLGRDYLETLMASQQAADWIRISEMLLGPVPPG
                     FVFLPKHKANAYK"
     exon            192..459
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     exon            460..966
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     exon            967..1008
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1161
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1278
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..1344
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1455
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1552
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1553..1628
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1629..1817
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1818..1946
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1947..2304
                     /gene="Dus3l"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2031..2036
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dus3l"
                     /note="hexamer: AATAAA"
     polyA_site      2052
                     /gene="Dus3l"
                     /note="major polyA site"
     regulatory      2285..2290
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dus3l"
                     /note="hexamer: ATTAAA"
     polyA_site      2304
                     /gene="Dus3l"
                     /note="major polyA site"
ORIGIN      
        1 attgctgtag tctgagcgtg cgcatttctt tctgtaggct ccagaggaca cgagcgaccc
       61 ggaagacttt cctgccacac tccagagctg gtgtgagggg catcgatggc ggagacggca
      121 gcggagagcg gtggtggcgg tgactccggg gttggcgcgt gcgaacgggg ggtggcgccc
      181 attaaagctc agtaccgcac aaccaaagaa cggttccacg aatatctgga tggagacaag
      241 caggagggtg catgccagga agtgcccaca ggagacccag ctgagccagg ggccaaaaga
      301 attcgcctgg aagatgggca ggaaaatggg aagacagagg tggcaattga atcccgtgaa
      361 aggcaggtgc ccaagagggc ccgtggccaa aacaaaagcc ggccccatgt gaagccagca
      421 cactacgaca aggacaggct ctgcccgtcc ttcctccagg agccggccac cccatgtgca
      481 tttggagacc gttgccgctt cctgcacgat gtggggcgct acctggagac caaaccggca
      541 gacctgggcc cccgctgcgt gctcttcgaa acctttggcc ggtgcccttt cagcatgacc
      601 tgtcgctttg ctggagcaca cctggggcct gaggggcaga acctggtgca ggaagaggtg
      661 gtggcccgct gtgcacagct cccttcagtg cggaatggct tagacagggc cctgcagcag
      721 cagctgcgga agcgccaagt gtgctttgag cgagctgagc aggccctgaa ccgcctcacc
      781 cagagcccca tgcccactgt tgtccctgag accactgtgg ccatggcgac cccaaagcag
      841 aatagctgcc atgcccagct agataccgta ggaggggctg gcaccccgca gagcagccct
      901 gtgccaacct gtggcccctt gacagacgag gacgtgatcc ggctgcggcc ctgtgagaag
      961 aagcggctag acatcagcgg aaagctgtat ctggctcctt taaccacgtg tggaaaccta
     1021 ccctttcgcc gcatttgcaa gcgctttggc gcggatgtga cctgcggtga gatggccgtg
     1081 tgtacgaacc tgctccaggg acagatgtct gagtgggctt tgctcaagcg ccacccctgt
     1141 gaggacatct ttggggtgca gctggagggc gcgttccctg acaccatgac caaatgtgcc
     1201 gagctcctca accgcaccat tgacgtggac ttcgtggaca tcaacgtggg ctgccccatc
     1261 gacctcgtct acaagaaggg tggtggctgt gcactcatga atcgctccgc caagttccaa
     1321 cagattgtgc ggggcgtgaa tgaggtgttg gacgtcccac tgactgtgaa gatgcgcaca
     1381 ggtgtccagg agcgtgtgag cctggcacac cgactgctgc ccgaactgcg ggactggggt
     1441 gtcgcactgg tcacgctcca tggccgctcc cgggaacagc gctacaccag gctggctgac
     1501 tggccctaca tagaacagtg tgccaaggtg gccagcccca tgcccctgtt tggaaatggg
     1561 gacatccttt cgtttgagga cgccaactgt gccatgcaga caggcgttgc ggggatcatg
     1621 gttgcccgtg gtgccttgct caagccctgg ctgttcacgg agatcaaaga acagaggcac
     1681 tgggacatct cgtcctccga gcgcctggac atcctgaggg acttcactca ctacggttta
     1741 gaacactggg gctccgacac acagggcgtg gagcggaccc ggcgcttcct gcttgagtgg
     1801 ctctcttttc tttgcaggta tgtgcccgtg ggcctgctcg agcgaccccc acagaggatc
     1861 aatgagaggc caccctatta cttaggccgt gactacctgg agacactgat ggccagccag
     1921 caggctgcag actggattcg catcagtgag atgctgcttg gaccagtacc tcctggcttc
     1981 gtcttcctgc ccaagcacaa ggccaatgcc tacaagtagc caatacagac aataaatatt
     2041 attcttctat catttctttt attttgttgg ttttttgaga caagatctcc tgttgtctgg
     2101 gctggccttg aactcctgga atcctaggca ctcaccgtcc atcatacttg gctttttttt
     2161 tttaggtgtc ctgttttgct ggccagtgtc cttgtgactt tggtttttca agacagggtt
     2221 gctctgtgta aaccaggctg gcctcaaact caagagagcc acttgtctgc ctctgaatgc
     2281 tgggattaaa gaagtgtacc accaaaaaaa aaaaaaaaaa a
//
