LOCUS       NM_001417930            2605 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus dihydrouridine synthase 1 like (Dus1l), transcript
            variant 10, mRNA.
ACCESSION   NM_001417930
VERSION     NM_001417930.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2605)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL663090.15.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17253011.2123898.1,
                                           SRR17784645.169526.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-177               AL663090.15        41948-42124         c
            178-424             AL663090.15        41206-41452         c
            425-533             AL663090.15        40632-40740         c
            534-584             AL663090.15        39997-40047         c
            585-697             AL663090.15        39563-39675         c
            698-780             AL663090.15        38757-38839         c
            781-884             AL663090.15        38420-38523         c
            885-1029            AL663090.15        38084-38228         c
            1030-1126           AL663090.15        37760-37856         c
            1127-1215           AL663090.15        37584-37672         c
            1216-1361           AL663090.15        36934-37079         c
            1362-1399           AL663090.15        35572-35609         c
            1400-1475           AL663090.15        35386-35461         c
            1476-1558           AL663090.15        35206-35288         c
            1559-2605           AL663090.15        33288-34334         c
FEATURES             Location/Qualifiers
     source          1..2605
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 84.54 cM"
     gene            1..2605
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /note="dihydrouridine synthase 1 like"
                     /db_xref="GeneID:68730"
                     /db_xref="MGI:MGI:1915980"
     exon            1..177
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            178..424
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             188..1909
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /EC_number="1.3.1.88"
                     /note="isoform 3 is encoded by transcript variant 10"
                     /codon_start=1
                     /product="tRNA-dihydrouridine(16/17) synthase
                     [NAD(P)(+)]-like isoform 3"
                     /protein_id="NP_001404859.1"
                     /db_xref="GeneID:68730"
                     /db_xref="MGI:MGI:1915980"
                     /translation="MPKLQGFEFWSRTLGGARHVVAPMVDQSELAWRLLSRRHGAQLC
                     YTPMLHAQVFVRDANYRKENLYCDVCPEDRPLIVQFCANDPEVFVQAALLAQDYCDAI
                     DLNLGCPQMIAKRGHYGAFLQEEWDLLQRMILLAHERLSVPVTCKIRVFPEIDKTVRY
                     AQMLEKAGCQLLTVHGRTKEQKGPMAGTASWEHIKAVRKAVGIPVFANGNIQCLQDVE
                     RCIQDTGVQGVMSAEGNLHNPALFEGRSPAVWELAEEYLDIVRQHPCPLSYVRAHLFK
                     LWHHTLQVHQQLREELAKVKTLEGVAAVSQALKLRCQEDMSRQQEGVRPADNLPAFHW
                     ICQPYIRPGPREGSKENSGGRSKRALEEEEGSMEGLSKNKLKKQLRNPHKTFDPSLKP
                     KYAKCDQCGNPKGNRCVFNLCRGCCKKRAFRETADCPGHGLLFKTKLEKSLAWKGTQP
                     GLQEAQQALHLDMDLVAEHSCSQNHSFGTSLEFLAHQQGLLKGGATLIHISSIQYLDK
                     MRRLRTAQGASTPHTRQSQPRGPTLLCESMRALIRPSRMSCVSSSSRAATVVLKAAAI
                     LCISADT"
     exon            425..533
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            534..584
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            585..697
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            698..780
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            781..884
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            885..1029
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1126
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1215
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1361
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1362..1399
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1475
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1558
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1559..2605
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2581..2586
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /note="hexamer: CATAAA"
     polyA_site      2605
                     /gene="Dus1l"
                     /gene_synonym="1110032N12Rik"
                     /note="major polyA site"
ORIGIN      
        1 acttccggcg gcgttgcgct gagtctgagc cacggcgctt ggcggctccc gccgccttcg
       61 tgcgggtcct gctggcggcg ccgcgggtca ggcagaggct acggggcctt gtgtgcccct
      121 ttctttggag cgtgcccgca gtcacagacc ttcatcgagc cctggccaac tccgacgtgt
      181 ggagaggatg cccaaactgc agggttttga gttttggagc cgcaccttgg ggggtgcccg
      241 acatgtggtg gcacccatgg tggaccagag tgagctagct tggagacttc tgagccgccg
      301 ccatggagcc cagctatgct acacccctat gctacatgcc caggtcttcg ttagagatgc
      361 taactaccgc aaagagaact tgtattgtga tgtgtgcccc gaggacaggc ctctcattgt
      421 gcagttctgt gccaatgacc cagaggtgtt tgtccaggcg gctctcctag cacaagatta
      481 ctgtgatgcc attgacctga acttgggctg cccacagatg atagccaaga gaggtcacta
      541 tggtgctttt ctgcaggagg agtgggacct tcttcaaaga atgattctgt tggctcatga
      601 gcgactctct gttcctgtca cgtgcaaaat tcgtgtcttc ccagaaattg acaagacagt
      661 gaggtacgcc cagatgctgg agaaggctgg ctgtcagctg ctgactgtgc atgggcgcac
      721 caaggagcag aaggggccca tggcaggaac agcctcctgg gaacacatca aggccgttcg
      781 gaaggctgtg ggaatccctg tgtttgccaa tgggaacatc caatgcctgc aggatgtgga
      841 gcggtgcatc caggacaccg gcgtgcaggg agtcatgagt gcagagggga acctgcacaa
      901 ccctgccctc tttgagggcc ggagtcctgc tgtgtgggag ctggccgagg agtacctgga
      961 cattgtgcgg caacaccctt gtccactatc gtatgtccgg gcccatctct tcaaactgtg
     1021 gcaccacacg ctacaggtac atcagcaact tcgagaagag ctggccaaag tgaagaccct
     1081 ggagggcgtg gctgctgtga gccaggcgct aaagcttcgg tgtcaggagg acatgtctag
     1141 gcagcaagaa ggagtgaggc cagctgacaa cttacctgct ttccattgga tctgccagcc
     1201 gtacatccgg ccaggaccta gggaagggag caaggagaat agtggtggtc gaagcaagcg
     1261 ggctctggag gaagaagaag gcagcatgga gggcttgtcc aagaataagc tgaagaaaca
     1321 actgaggaac cctcacaaaa cctttgaccc ttccctgaaa cccaaatatg ccaagtgtga
     1381 ccagtgtgga aatccaaagg gcaataggtg tgtgtttaat ctgtgccgtg gctgctgcaa
     1441 gaagcgagct ttcagagaga cagcagattg cccaggtcat ggattgcttt ttaagaccaa
     1501 attagagaag tctttggcct ggaaagggac ccagcctgga ctgcaggaag cccagcaggc
     1561 tcttcacctt gacatggatc tggttgcgga gcacagctgc tctcagaatc atagctttgg
     1621 cacgtcgttg gaattccttg cccatcagca gggacttctc aaaggtggtg ctacgctgat
     1681 ccacatctcg agcatacagt atctggacaa gatgagaagg ctcagaacag cccaaggggc
     1741 ctccacacca cacactcggc agtcccaacc ccgtggaccc accttgctgt gtgagtcgat
     1801 gcgggcatta ataaggccct ccagaatgag ctgtgtcagc tcatcttcca gagctgcaac
     1861 tgttgtgttg aaggctgcag ccatcttgtg catatcagct gacacatagg ggctgaagta
     1921 ctacaggaca gaagccacaa gctgtccact gctcctcaga aggtctgcat tccacacagc
     1981 cctaaccatc caagccccct tgccccaaca ccgacgctta cttggataag agcccggtta
     2041 cgaatctggg tgtacagtgt cctgacgtga ggggccaggt acatgtccag gagcaggtta
     2101 tcctgcagag gagagctggt cagagacccc cgaggtgtgc acacctagct cagttccagt
     2161 gtgccttacc cttgcgcctt accttcatct cgtccagcat cttcaagcat gaggcatact
     2221 tggattcata gaatttgaag atgatgtctc tgacctgtgg ctccagctcc aggaacagct
     2281 tgaaggaact gaggatacca caatgctcaa ctaagaaggg acggaagggc ctggctggac
     2341 aagagaaggt gggagcccac tacccaactt acctgctgga gatgacattt cgttgcagct
     2401 cctgccggtc aaaggtggct aaggcacaca ggccaccata gacagccaca ttgctggggg
     2461 acagcagctg ggaggcagaa ggggaagtgg gtccagaaac ctggggtcct gggccattga
     2521 cgggcacaca gaccaaggag gaagcccaaa gttggggcct actctacctt tcccactacc
     2581 cataaagacg atgcttagac cctca
//
