LOCUS       NM_026854               3145 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus DTW domain containing 2 (Dtwd2), transcript variant 1,
            mRNA.
ACCESSION   NM_026854 XM_355059 XM_911856 XM_991344
VERSION     NM_026854.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3145)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB868459.1, AK004450.1, AK144689.1, AK033232.1 and AC112984.21.
            
            On Jan 14, 2010 this sequence version replaced NM_026854.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK144689.1, BC139347.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                BB868459.1         2-27
            27-1291             AK004450.1         2-1266
            1292-1292           AK144689.1         1268-1268
            1293-1816           AK004450.1         1267-1790
            1817-1862           AK033232.1         62-107
            1863-2501           AK033232.1         110-748
            2502-2502           AC112984.21        84287-84287         c
            2503-2912           AK033232.1         749-1158
            2913-2913           AC112984.21        83876-83876         c
            2914-3145           AK033232.1         1160-1391
FEATURES             Location/Qualifiers
     source          1..3145
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 27.09 cM"
     gene            1..3145
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
                     /note="DTW domain containing 2"
                     /db_xref="GeneID:68857"
                     /db_xref="MGI:MGI:1916107"
     exon            1..281
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..960
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
                     /EC_number="2.5.1.25"
                     /note="isoform 1 is encoded by transcript variant 1; DTW
                     domain-containing protein 2; tRNA-uridine
                     aminocarboxypropyltransferase 2"
                     /codon_start=1
                     /product="tRNA-uridine aminocarboxypropyltransferase 2
                     isoform 1"
                     /protein_id="NP_081130.1"
                     /db_xref="CCDS:CCDS37815.1"
                     /db_xref="GeneID:68857"
                     /db_xref="MGI:MGI:1916107"
                     /translation="MEPQAEERTLGEPAPPPSGALASPTPDEEERTEGGAPPTATPAG
                     ASGDSTSADGLWGLPVEHAERRPECGRCSRPQKVCLCPYLPVRPLQISTHLYIIQHPA
                     EESRVLRTVPLLAACLPPDRCTVKIGRRFSEERDVELATVCRDSGTLILYPGAEATNL
                     EEFILDSPVYPSTIILIDGTWSQAKDIFYKNSLFRLPKQVQLKTSVCSQYVIRMQPTN
                     RCLSTLECAAVALSILEKNNCIQETLLRPLQALCSFQLQHGAQIRLSKEYLLRNGLYP
                     KPMPKNKRKLRKMELLMNSVKI"
     exon            282..372
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            373..467
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            468..660
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            661..789
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            790..3145
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1794..1799
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1819
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
                     /note="major polyA site"
     regulatory      2459..2464
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2478
                     /gene="Dtwd2"
                     /gene_synonym="1190002H09Rik; 8030470C17Rik"
ORIGIN      
        1 gcgtggcgcc ccccggcggc ggcggcgctc cttccatgcg agggcctgac tctaccacca
       61 cccatggagc cgcaggccga ggagcgaact ctcggggagc ctgcgcctcc gccttctggc
      121 gccttggcgt caccgacgcc ggacgaagag gagcggaccg agggcggcgc accgccgacg
      181 gcgactcccg cgggcgcatc gggggacagc acgagtgcag acgggctctg ggggctgccg
      241 gtggagcacg cggagcgcag gcccgagtgc ggccgctgca gccggcccca gaaagtgtgc
      301 ttatgtccat atctcccagt gcgcccactc cagatctcta cccacttgta cataatccag
      361 catccagcag aggaaagcag agtgttgcgc acagtccctc tgctagcagc atgccttccc
      421 ccagacagat gcacagtcaa gattggccgc cgcttcagtg aagagcgaga tgttgaactt
      481 gcaactgttt gccgggactc tggtacatta atattatatc caggggctga agctactaat
      541 ttggaagaat ttatattaga ttctcctgtt tatccttcca caatcatcct cattgatggt
      601 acatggagcc aggctaagga cattttctat aagaattcct tgttccgact tcccaaacag
      661 gtgcagttaa aaactagcgt ttgtagtcag tatgtaattc ggatgcaacc aacaaacagg
      721 tgcctttcta ccctggagtg cgctgctgtt gctctttcca tcttggagaa aaacaattgc
      781 atacaagaga ccctgctccg cccccttcaa gctctgtgtt ctttccagct tcagcatggc
      841 gctcagattc gcctcagcaa ggaatatctt ctgagaaacg gattgtatcc caagccaatg
      901 ccaaagaaca aacgcaaact caggaagatg gagctgttga tgaacagtgt taaaatttag
      961 cacgtctgtc cctgtggtgc tagtttacct gtcactggct gacaagactg tgttacatct
     1021 tcccagtcta ggctttcgct ctgaagaatc gttggcccat tcttgtgctg aaggacgagg
     1081 gctgctccac agcgccttat ggttcacttc cgttgactgt gaaaagcagt ttcacactgc
     1141 ctctcgtttt gtttttgttt ttgtttttgt tgtttttgtt ttttcaatac aaggtttctc
     1201 tgtgtagcct gtagaccagg ctggcctcaa actcagagat ctggctgctt ctgcctccca
     1261 agttctgggc tgaaaagcat gccccacctc tgtctagctt ctgtatttgc ttttaaacat
     1321 gtgcttccaa tacttttttt ttttttttaa agaatctatt caaaatacga ttagtctaga
     1381 gtaaggagct gttgtttgta aaatgaggaa aattgtgtct gggaacatgt tcccgtcagt
     1441 gtttataggt atgtaggtgt agatcactga tggaatatac cccgtgaaac taatgtttca
     1501 gcctagtgaa tgaaattata agtgtgaagt aagtgacaca gagggcagtt tatgtcatta
     1561 agtagtgtaa gggaataggg agacgttact gtttacagtt gtactcggac tcagctaatg
     1621 tgactcacgt cttctgttag catctgaatt cctgtggaga catataattt tgaaataacc
     1681 tgcattctct atgggggatg ctgtgcataa ctttcagtgt tcactgagca agctaactgg
     1741 tggtaagagg tttttgatga agtttctaca tggaaatgac tgaagtaaat tataataaag
     1801 ctatcatttt aagaacatat ttctataagt agctctactt actttttttt tttttttttt
     1861 ttaaagaaaa acaactttca atgtggaaga tacatgccct taccttattt ggagaatatt
     1921 tactgatatt ttgtatagaa aaagagaaat ttatacattt tatatttata tccaatttac
     1981 agttaagcat acactttggc aagatcacga tgtttcattt tgactgttgt tcacaattgc
     2041 taaggtttcc taaattcagg gtgacagtgg aagggagagt caagcatgac ttagtttgtg
     2101 atctttagtt gtgattttga taaatacctc tgtgtgtggc atgaacacac accagtttct
     2161 gattattttt atgctttttt tgtttgtttg ttattgggtt agatcagaca ctcattaaga
     2221 acttggctgg tcctaattag aatgctaaca gatatgtagc atgttacaga aagatattaa
     2281 aatttaggtt tgtcttaagt tgctgactta tatttgcatt taaaaataag tcggtctttt
     2341 ataacctaaa tgtctagtat caattgaata tttatataat aatgaaatag tagtattatg
     2401 tataatggtt tcttaaggaa tgagttaaaa tcatctcata ataatttttt atgttgaaaa
     2461 taaactttat aaaatctttt gagtgctatg attgctcttt aagaacaatc tgacaaatga
     2521 tactatttat atttccaaac atcaatttgt gtttaccatt tagaataact tttatgtttt
     2581 aaacataata cttaaatact taaagtttat tactttggct acatattttt tctttctttc
     2641 ttttttaaga agatatatct agatagaaga aagatggcag agttgagata cttggcactt
     2701 tgatgcatct gtgaatccta acagcatcag atacatggct acagggtgtg gggagtgaca
     2761 tgtaaagtca ggagtttagc agcagacaga gattaggcaa atccagaaaa accagaagtt
     2821 tagatttgtt gaagaaattg gaccctaagg tggtatgtgt tgggagccgc ccccacattc
     2881 gccgtcacaa gatggcgcta acatcctgtg ttctaagtgg tatacaaata atctgcgcat
     2941 gtgccaagag taattttcca ctacatgtac tctgccttta ctcggccatg ggctgcagcc
     3001 aatcagggag tgatgcgtcc taggcgaagg ataactctcc taaataggga cagggtttcg
     3061 ctttcgtttt tgggggcttt cgtttttggg cttggggctt gcgctcctgg ctcctgaaga
     3121 tgtaagcaat aaagttttgc cgcag
//
