LOCUS       NM_007883               5771 bp    mRNA    linear   ROD 16-JAN-2024
DEFINITION  Mus musculus desmoglein 2 (Dsg2), mRNA.
ACCESSION   NM_007883 XM_904481 XM_918851
VERSION     NM_007883.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5771)
  AUTHORS   Chen D, Wirth KM, Kizy S, Muretta JM, Markowski TW, Yong P, Sheka
            A, Abdelwahab H, Hertzel AV, Ikramuddin S, Yamamoto M and Bernlohr
            DA.
  TITLE     Desmoglein 2 Functions as a Receptor for Fatty Acid Binding Protein
            4 in Breast Cancer Epithelial Cells
  JOURNAL   Mol Cancer Res 21 (8), 836-848 (2023)
   PUBMED   37115197
  REMARK    GeneRIF: Desmoglein 2 Functions as a Receptor for Fatty Acid
            Binding Protein 4 in Breast Cancer Epithelial Cells.
REFERENCE   2  (bases 1 to 5771)
  AUTHORS   Chen L, Liu Y, Xu Y, Afify SM, Gao A, Du J, Liu B, Fu X, Liu Y, Yan
            T, Zhu Z and Seno M.
  TITLE     Up-regulation of Dsg2 confered stem cells with malignancy through
            wnt/beta-catenin signaling pathway
  JOURNAL   Exp Cell Res 422 (1), 113416 (2023)
   PUBMED   36375513
  REMARK    GeneRIF: Up-regulation of Dsg2 confered stem cells with malignancy
            through wnt/beta-catenin signaling pathway.
REFERENCE   3  (bases 1 to 5771)
  AUTHORS   Schinner C, Xu L, Franz H, Zimmermann A, Wanuske MT, Rathod M,
            Hanns P, Geier F, Pelczar P, Liang Y, Lorenz V, Studle C, Maly PI,
            Kauferstein S, Beckmann BM, Sheikh F, Kuster GM and Spindler V.
  TITLE     Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy
            by Involving an Integrin-alphaVbeta6/TGF-beta Signaling Cascade
  JOURNAL   Circulation 146 (21), 1610-1626 (2022)
   PUBMED   36268721
REFERENCE   4  (bases 1 to 5771)
  AUTHORS   Myo Min KK, Rojas-Canales D, Penko D, DeNichilo M, Cockshell MP,
            Ffrench CB, Thompson EJ, Asplund O, Drogemuller CJ, Prasad RB,
            Groop L, Grey ST, Thomas HE, Loudovaris T, Kay TW, Mahoney MG,
            Jessup CF, Coates PT and Bonder CS.
  TITLE     Desmoglein-2 is important for islet function and beta-cell survival
  JOURNAL   Cell Death Dis 13 (10), 911 (2022)
   PUBMED   36309486
  REMARK    GeneRIF: Desmoglein-2 is important for islet function and beta-cell
            survival.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5771)
  AUTHORS   Qiu Z, Zhao Y, Tao T, Guo W, Liu R, Huang J and Xu G.
  TITLE     Activation of PPARalpha Ameliorates Cardiac Fibrosis in
            Dsg2-Deficient Arrhythmogenic Cardiomyopathy
  JOURNAL   Cells 11 (20), 3184 (2022)
   PUBMED   36291052
  REMARK    GeneRIF: Activation of PPARalpha Ameliorates Cardiac Fibrosis in
            Dsg2-Deficient Arrhythmogenic Cardiomyopathy.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5771)
  AUTHORS   Kieffer-Combeau S, Meyer JM and Lesot H.
  TITLE     Cell-matrix interactions and cell-cell junctions during epithelial
            histo-morphogenesis in the developing mouse incisor
  JOURNAL   Int J Dev Biol 45 (5-6), 733-742 (2001)
   PUBMED   11669375
REFERENCE   7  (bases 1 to 5771)
  AUTHORS   Gallicano GI, Kouklis P, Bauer C, Yin M, Vasioukhin V, Degenstein L
            and Fuchs E.
  TITLE     Desmoplakin is required early in development for assembly of
            desmosomes and cytoskeletal linkage
  JOURNAL   J Cell Biol 143 (7), 2009-2022 (1998)
   PUBMED   9864371
REFERENCE   8  (bases 1 to 5771)
  AUTHORS   Fausser JL, Schlepp O, Aberdam D, Meneguzzi G, Ruch JV and Lesot H.
  TITLE     Localization of antigens associated with adherens junctions,
            desmosomes, and hemidesmosomes during murine molar morphogenesis
  JOURNAL   Differentiation 63 (1), 1-11 (1998)
   PUBMED   9615388
REFERENCE   9  (bases 1 to 5771)
  AUTHORS   King IA, Angst BD, Hunt DM, Kruger M, Arnemann J and Buxton RS.
  TITLE     Hierarchical expression of desmosomal cadherins during stratified
            epithelial morphogenesis in the mouse
  JOURNAL   Differentiation 62 (2), 83-96 (1997)
   PUBMED   9404003
REFERENCE   10 (bases 1 to 5771)
  AUTHORS   Ruiz P, Brinkmann V, Ledermann B, Behrend M, Grund C, Thalhammer C,
            Vogel F, Birchmeier C, Gunthert U, Franke WW and Birchmeier W.
  TITLE     Targeted mutation of plakoglobin in mice reveals essential
            functions of desmosomes in the embryonic heart
  JOURNAL   J Cell Biol 135 (1), 215-225 (1996)
   PUBMED   8858175
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC132091.3, AK029320.1 and
            BG092030.1.
            
            [WARNING] On Jan 17, 2024 this sequence was replaced by
            NM_007883.4.
            
            On Jan 30, 2016 this sequence version replaced NM_007883.2.
            
            Summary: This gene encodes a member of the cadherin family of
            proteins that forms an integral transmembrane component of
            desmosomes, the multiprotein complexes involved in cell adhesion,
            organization of the cytoskeleton, cell sorting and cell signaling.
            The encoded preproprotein undergoes proteolytic processing to
            generate a mature, functional protein. Mice lacking the encoded
            protein die in utero. Mutant mice lacking a part of the
            extracellular adhesive domain of the encoded protein develop
            cardiac fibrosis and dilation. This gene is located in a cluster of
            desmosomal cadherin genes on chromosome 18. [provided by RefSeq,
            Jan 2016].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB072269.1, BC131653.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-271               AC132091.3         34470-34740
            272-307             AC132091.3         49885-49920
            308-442             AC132091.3         51336-51470
            443-604             AC132091.3         55436-55597
            605-749             AC132091.3         55730-55874
            750-916             AC132091.3         56908-57074
            917-1054            AC132091.3         59104-59241
            1055-1240           AC132091.3         59333-59518
            1241-1506           AC132091.3         66344-66609
            1507-1649           AC132091.3         68230-68372
            1650-1877           AC132091.3         68668-68895
            1878-1958           AC132091.3         70460-70540
            1959-3209           AK029320.1         1-1251
            3210-3210           AC132091.3         78361-78361
            3211-5547           AK029320.1         1252-3588
            5548-5771           BG092030.1         2-225               c
FEATURES             Location/Qualifiers
     source          1..5771
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 11.42 cM"
     gene            1..5771
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /note="desmoglein 2"
                     /db_xref="GeneID:13511"
                     /db_xref="MGI:MGI:1196466"
     exon            1..271
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     CDS             212..3580
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /codon_start=1
                     /product="desmoglein-2 preproprotein"
                     /protein_id="NP_031909.2"
                     /db_xref="CCDS:CCDS29084.1"
                     /db_xref="GeneID:13511"
                     /db_xref="MGI:MGI:1196466"
                     /translation="MARSPGDRCALLLLVQLLAVVCLDFGNGLHLEVFSPRNEGKPFP
                     KHTHLVRQKRAWITAPVALREGEDLSRKNPIAKIHSDLAEEKGIKITYKYTGKGITEP
                     PFGIFVFDRNTGELNITSILDREETPYFLLTGYALDSRGNNLEKPLELRIKVLDINDN
                     EPVFTQEVFVGSIEELSAAHTLVMKITATDADDPETLNAKVSYRIVSQEPANSHMFYL
                     NKDTGEIYTTSFTLDREEHSSYSLTVEARDGNGQITDKPVQQAQVQIRILDVNDNIPV
                     VENKMYEGTVEENQVNVEVMRIKVTDADEVGSDNWLANFTFASGNEGGYFHIETDTQT
                     NEGIVTLVKEVDYEEMKKLDLSIIVTNKAAFHKSILSKYKATPIPITVKVKNVVEGIH
                     FKSSVVSFRASEAMDRSSLSRSIGNFQVFDEDTGQAAKVTYVKVQDTDNWVSVDSVTS
                     EIKLVKIPDFESRYVQNGTYTAKVVAISKEHPQKTITGTIVITVEDVNDNCPVLVDSV
                     RSVCEDEPYVNVTAEDLDGAQNSAPFSFSIIDQPPGTAQKWKITHQESTSVLLQQSER
                     KRGRSEIPFLISDSQGFSCPERQVLQLTVCECLKGGGCVAAQYDNYVGLGPAAIALMI
                     LALLLLLLVPLLLLICHCGGGAKGFTPIPGTIEMLHPWNNEGAPPEDKVVPSLLVADH
                     AESSAVRGGVGGAMLKEGMMKGSSSASVTKGQHELSEVDGRWEEHRSLLTAGATHHVR
                     TAGTIAANEAVRTRATGSSRDMSGARGAVAVNEEFLRSYFTEKAASYNGEDDLHMAKD
                     CLLVYSQEDTASLRGSVGCCSFIEGELDDLFLDDLGLKFKTLAEVCLGRKIDLDVDIE
                     QRQKPVREASVSAASGSHYEQAVTSSESAYSSNTGFPAPKPLHEVHTEKVTQEIVTES
                     SVSSRQSQKVVPPPDPVASGNIIVTETSYAKGSAVPPSTVLLAPRQPQSLIVTERVYA
                     PTSTLVDQHYANEEKVLVTERVIQPNGGIPKPLEVTQHLKDAQYVMVRERESILAPSS
                     GVQPTLAMPSVAAGGQNVTVTERILTPASTLQSSYQIPSETSITARNTVLSSVGSIGP
                     LPNLDLEESDRPNSTITTSSTRVTKHSTMQHSYS"
     exon            272..307
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            308..442
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            443..604
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            605..749
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            750..916
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1054
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1240
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1506
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            1507..1649
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            1650..1877
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            1878..2105
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            2106..2227
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            2228..2557
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
     exon            2558..5771
                     /gene="Dsg2"
                     /gene_synonym="D18Ertd293e"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgcctcgta cctccccgcg gagcgaacac attcccctcc tccatctagg ctgtggcccg
       61 gcccaaggct accctttctg acccgggcac acctggaacc gcaccccggg tcccgcagag
      121 tcagagaagg gcggccccgg gagggacctg cccaggagga tccgcagggc gccggcgagg
      181 cccggaggcg agggcgcggc ggatcgaggc gatggcgcgg agcccgggtg accggtgcgc
      241 cctgctgctg ctggtgcagc tgctggcggt ggtctgcttg gactttggaa acggacttca
      301 cttagaggtc ttcagcccaa gaaatgaagg caaaccgttc cctaagcaca ctcacttggt
      361 tcgtcaaaag agggcctgga tcactgcccc tgtggctctg cgggagggcg aagacctgtc
      421 cagaaagaac ccgattgcca agatacactc tgaccttgca gaagaaaaag ggataaaaat
      481 cacgtacaag tacactggga agggaattac agaaccgcct ttcggcatat tcgtctttga
      541 tagaaacaca ggagaactga acatcactag cattcttgac cgggaagaaa caccatattt
      601 tctgctgaca ggctatgcat tggactccag aggaaacaac ctggaaaagc ccttggaact
      661 acgcatcaaa gttctggaca tcaatgacaa cgagccagtg ttcacacagg aggtctttgt
      721 tgggtccatt gaggaattga gtgcagcaca tacacttgtg atgaaaatca ccgccacaga
      781 tgcagatgac ccggagactc tgaatgctaa agtctcctac agaattgtct ctcaggagcc
      841 tgcaaatagt catatgttct acctaaataa agacacgggg gagatctata cgaccagttt
      901 tactttggac agagaggaac acagcagcta ttccttgacg gtggaagcaa gagatggtaa
      961 cgggcagata acagacaagc cagtccagca agctcaagtt cagatccgta tattggatgt
     1021 caatgacaat atacctgtgg tagaaaacaa aatgtatgag gggacagtgg aagaaaacca
     1081 ggtcaatgta gaagtcatgc ggatcaaagt gaccgatgca gatgaagtgg gctctgataa
     1141 ctggctagca aactttacat ttgcatcagg aaatgaaggg ggctatttcc acattgagac
     1201 tgacacacag actaatgaag ggattgtgac ccttgtcaag gaagtggact atgaagaaat
     1261 gaagaagcta gacttgagca tcattgtcac taacaaagca gctttccaca agtccattct
     1321 gagcaagtac aaggccacgc ccattcccat cactgtcaag gtcaagaacg tggttgaagg
     1381 cattcatttc aagagcagcg tagtctcttt ccgagctagt gaggcaatgg atagatccag
     1441 cctcagcagg tcgattggaa attttcaagt ttttgatgaa gacactggtc aagcagctaa
     1501 agtaacatat gtaaaagtgc aagacactga caactgggtc tctgtggact ccgtcacttc
     1561 agagattaag cttgtaaaga ttcctgactt tgaatctaga tatgtccaaa atggtaccta
     1621 cactgcaaag gttgtggcca tatccaaaga acatcctcaa aaaaccatca ctggcaccat
     1681 cgttatcact gttgaagacg tcaatgacaa ttgtcccgtg ctggtggact ctgtacggag
     1741 tgtctgtgag gatgaaccat atgtgaatgt cactgcagag gatttggatg gggcccagaa
     1801 cagtgcgcca ttcagcttct ccatcattga ccagcctcct ggaacggcac agaagtggaa
     1861 aataacgcac caggaaagta ccagtgtgct gctgcagcag agcgagcgga aacgcgggag
     1921 aagtgagatt cccttcctca tttccgacag ccagggcttc agctgccccg aaaggcaggt
     1981 ccttcagctc actgtatgcg agtgtctgaa gggcggtggc tgtgtggctg cacagtatga
     2041 caactacgtc gggttgggcc ctgccgccat cgctctcatg attctagcac tcctgctcct
     2101 gctcctggtg ccgctcttgc tgttgatatg ccactgtgga gggggcgcca aaggcttcac
     2161 ccccattcct gggacaatag agatgctgca cccttggaat aatgaagggg cacctcctga
     2221 ggacaaggtg gtgccatcgc ttctggtggc cgatcatgca gagagctcgg cagtgagagg
     2281 cggcgtagga ggtgcgatgc tcaaggaagg catgatgaaa ggcagcagct cagcttccgt
     2341 taccaaaggg cagcatgagc tgtctgaggt tgacggaaga tgggaagaac acagaagcct
     2401 cctcaccgct ggggccactc accatgtaag gacagcagga accatcgctg ccaacgaagc
     2461 cgtaaggaca agagccacgg ggtcttccag agacatgagt ggggctcgag gagccgttgc
     2521 cgtgaatgag gaattcttaa gaagttactt cacagagaaa gcggcctcct acaatgggga
     2581 agacgacctt cacatggcca aagactgcct tctcgtttac tctcaggaag acacggcctc
     2641 cctccgaggc tcggtcgggt gctgcagttt catcgaggga gaactcgatg acctgttcct
     2701 ggatgatctt ggccttaaat tcaagaccct agctgaagtt tgcctaggtc gaaagatcga
     2761 tctggatgtg gacattgaac agaggcagaa gccggtcaga gaagcgagcg tgagtgcagc
     2821 ttctggctcg cactatgagc aagcggtaac cagctcagag agcgcgtact cctctaacac
     2881 cggcttcccc gcccccaaac ctctgcacga agtgcacaca gagaaagtca cacaggaaat
     2941 cgtcactgag agctctgtat cttccaggca gagtcagaag gtagtaccgc cacctgatcc
     3001 tgtggcttct ggtaatatta tagtgacgga aacttcctat gccaaaggct cagcagtgcc
     3061 acccagcact gtgctcctgg ctcccagaca gccacagagc ctgatcgtga cagagagggt
     3121 gtatgctcca acctccacct tggtggatca gcattatgcc aatgaagaaa aagtccttgt
     3181 taccgaacga gtgatccagc ctaatggggg catccctaag ccccttgagg tcacccagca
     3241 tctgaaagat gcacagtatg taatggtgag ggaaagagag agcatccttg ctcccagctc
     3301 aggcgtgcag cccactctgg caatgcccag cgtggcagca ggaggacaga atgtcaccgt
     3361 gacagaaaga atactaactc ctgcttccac tctgcagtcc agctaccaga ttcccagtga
     3421 aacctccatc acggctagga acactgtgct ctctagtgtg ggaagcatag gtcctctgcc
     3481 caatttagat ctagaggaat ctgatcgtcc caattctact ataaccacat cttccaccag
     3541 ggtcaccaag catagcacca tgcaacattc ttactcctaa agagaagcca gccgcagtcg
     3601 gatctggacc ttaactagca tccactggat gtgtgtgtcc atgcccctaa tgttataaca
     3661 gccacacaag acttgcacat tggaaaaact tattgacatg ccaaacaaag acaccatgtc
     3721 tcaggtaggg ttgtatttca gcaatgctct gtgattattg ggggatggag ttaagatgct
     3781 agttcctcag tgccttttag agtactgtgc aagcaatact cgcaaacagg acatgtaaaa
     3841 ttgagttcca agaacttaca aaactaaagc agggtatcta attcatcagg tccaggaggc
     3901 tgggtctctg cacaatgcat tgatattcag cagggacagt tccacccctt atattacaga
     3961 gccacacagg ttataggtac caaatagctc atccacccag agacacatct ccactctttc
     4021 atctccactg gaaccctgag tacaccagag ggaagaaaga aagaaagaaa gagagagaga
     4081 gagagagaga gagagagaga gagagagaac actggagccc tttttaactg tctaaagttg
     4141 acagacttta gaacactgtc aggataagaa tacatagtgt gtatttctct gcacatacca
     4201 tgtcctgtga gctgaaaaaa aaaatgactt catatttttc ctcacttacc aaaggtccta
     4261 aaaatattga gcatttcaaa ttagttttat aatctaacta atcatgatag ccaggtgtgg
     4321 tggtgcaggc ctttagtcca gaactcaaga agcaggcaaa tctctccggg ttcgaggcca
     4381 atctggtgta tataaagggt tccaggacac ccagggctac atagaaaaac cctgtctcaa
     4441 aaaagcaagc aaaacaaaca acaacaaata ctagtaatcc aggataaaat tcctagttaa
     4501 cttttctgca atgtgatggc agtctatgaa ggaaacgtct tcatagatct gtttcctatc
     4561 tacaagttca tgcacttagg ggctgcacaa atgaccgagt ggctaagagc acattactga
     4621 ctgctcttgc agagaaccct acttcagttt ctgacaacta catactatgg ctcacaacca
     4681 cctctaattc caactcaagg gatctgatgc tctctaatgg actccaaaga cattgcactc
     4741 acagttgagt ggttagtgag cagccgagtt ccactcttgc atcctcagtg cctctcacag
     4801 ccgccatatc cccctcttgc cattgaccga cttccatcct cagtgcctct cacagaaccc
     4861 cagccattat ctatggcaca agataagttc cacaaaccac tcttttacaa ttagtcaaat
     4921 atcaagaaga ctcagtagtt cagtaattct gaattatgaa ctttaccatc ttgatatctg
     4981 acataattgg ctggtcatga gttgatatgc atgaagtaaa tactttatca taaaaaccct
     5041 tgagtaactg gcccaatttc attcaacttc cttgccttga ttctttcaag aagttgtttg
     5101 gattctacag aacatcaatg gaaaatatta cataacaaaa atttgcttct aaaaaataat
     5161 gtttcaaaac ctatgtatat atcagtcata atttatatcc atgtatctca cccaaaaaat
     5221 gttaagagcc atcaaatttc tggatatttt gctaggaaaa tgaaattcta cacttatttt
     5281 ttgtagactt tttttaaatg ctgtttacat gaattgtatt ttggaaaaaa tattatactg
     5341 tgcaccctgt gatgcatgaa gtgattttat gtatggtctg ctatgtgggc agaggtcacc
     5401 ttattcctat gatctggaat tgtttacttt ctacaaagta agctttgtgg ggattttgct
     5461 ttcattttct ttgtagctga tgttatttta ccaggtgtgc agcaggaatt acaccactgt
     5521 gtggaattat aaatacatcc catgtgcaaa aaaaaacaaa aaaaacaaaa aaaaaaaaac
     5581 ctacaactca gtcttgcgcg ccccctgggt ggctttgagg ctccactgct cttttgtgca
     5641 gagtaccatc ttccttgttt ccccaaaggg tgatttgcat tcgtttttac atttgttcct
     5701 tgggaggttt gcatttgtgt gtgtatccat gtaaaatatt ttaataaaaa ggccaccttc
     5761 tttcagagta a
//
