LOCUS       NM_024176                999 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus DR1 associated protein 1 (Drap1), transcript variant
            2, mRNA.
ACCESSION   NM_024176 XM_908371 XM_920806 XM_920811
VERSION     NM_024176.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Trask,M.C., Tremblay,K.D. and Mager,J.
  TITLE     Yin-Yang1 is required for epithelial-to-mesenchymal transition and
            regulation of Nodal signaling during mammalian gastrulation
  JOURNAL   Dev Biol 368 (2), 273-282 (2012)
   PUBMED   22669107
REFERENCE   2  (bases 1 to 999)
  AUTHORS   Iratni,R., Yan,Y.T., Chen,C., Ding,J., Zhang,Y., Price,S.M.,
            Reinberg,D. and Shen,M.M.
  TITLE     Inhibition of excess nodal signaling during mouse gastrulation by
            the transcriptional corepressor DRAP1
  JOURNAL   Science 298 (5600), 1996-1999 (2002)
   PUBMED   12471260
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122861.4 and AK087456.1.
            
            On Mar 22, 2014 this sequence version replaced NM_024176.1.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site, compared to variant 1. The encoded isoform (2) is
            shorter than isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC002090.1, AK010152.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-174               AC122861.4         159311-159484       c
            175-977             AK087456.1         1-803
            978-999             AC122861.4         157309-157330       c
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 4.32 cM"
     gene            1..999
                     /gene="Drap1"
                     /gene_synonym="2310074H19Rik; NC2-alpha"
                     /note="DR1 associated protein 1"
                     /db_xref="GeneID:66556"
                     /db_xref="MGI:MGI:1913806"
     exon            1..307
                     /gene="Drap1"
                     /gene_synonym="2310074H19Rik; NC2-alpha"
                     /inference="alignment:Splign:2.1.0"
     CDS             266..883
                     /gene="Drap1"
                     /gene_synonym="2310074H19Rik; NC2-alpha"
                     /note="isoform 2 is encoded by transcript variant 2;
                     dr1-associated corepressor; Dr1 associated protein 1
                     (negative cofactor 2 alpha)"
                     /codon_start=1
                     /product="dr1-associated corepressor isoform 2"
                     /protein_id="NP_077138.1"
                     /db_xref="CCDS:CCDS29462.1"
                     /db_xref="GeneID:66556"
                     /db_xref="MGI:MGI:1913806"
                     /translation="MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALEL
                     FLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDMQGDGEDNHV
                     DGDKGPRRGRKPGSSGRKNGGTGSKGKDKKLSGTDSEQEDESEDTDTDGEEETPQLPP
                     QASHPPAHFQSPPTPFIPFTSPLPLPPAPPGPSAADAEDEEDYDS"
     exon            308..380
                     /gene="Drap1"
                     /gene_synonym="2310074H19Rik; NC2-alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            381..474
                     /gene="Drap1"
                     /gene_synonym="2310074H19Rik; NC2-alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            475..594
                     /gene="Drap1"
                     /gene_synonym="2310074H19Rik; NC2-alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            595..688
                     /gene="Drap1"
                     /gene_synonym="2310074H19Rik; NC2-alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            689..777
                     /gene="Drap1"
                     /gene_synonym="2310074H19Rik; NC2-alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            778..999
                     /gene="Drap1"
                     /gene_synonym="2310074H19Rik; NC2-alpha"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttgggggg cgggtgggcg tggcgggcga gcccggggaa ggacgcgcac cgccccagag
       61 gatccgaagc ccagcgctcg agtttgggga gctgcttgtc tacgggcggc actaggaccc
      121 tgcgggaagt ggtgtaggcg gagtaaacgg caccaggacc cggggagggt gggggggggg
      181 accgcggcgg gccggcggcg gacaggcccg gggccgggag gctgcgggcg gcggcgctgg
      241 gcccggcgca acgagaggcc ccgagatgcc aagcaagaag aagaagtata acgcgcggtt
      301 tccgccggcg cggatcaaaa agatcatgca gacggacgaa gagattggga aggtggcggc
      361 agctgtgcct gtcatcatct cccgggccct tgagctcttc ctggagtccc tgttgaagaa
      421 ggcttgccag gtgacccagt ctcgaaatgc caaaaccatg accacgtccc acctgaagca
      481 gtgcattgaa ctcgagcagc agtttgactt cttgaaagac ttggtggcat cagtgcctga
      541 catgcagggg gatggggagg acaaccacgt ggatggggac aagggtcctc gaaggggccg
      601 gaaaccgggc agcagcggca ggaagaacgg aggcacggga agcaaaggca aagacaagaa
      661 gctgtccggg acagactctg agcaggagga tgagtctgag gatacagata ctgatgggga
      721 agaagagaca ccacagcttc caccccaagc cagtcaccct cctgcccact ttcagagccc
      781 tccaactccc ttcataccct tcacatctcc cctgcctttg ccaccagcac cccccggccc
      841 ctcagcagcc gatgcagagg atgaagagga ttatgactcc tagcgccctg tgcccctgta
      901 ccccagccat gctctcttct agttagtatt aattgctttg gggagaggag aaaggtggga
      961 ttgttcttaa atttattaaa aaaaaaaaaa aaaaaggat
//
